CN102600287B - Compound medicine for treating toothache - Google Patents
Compound medicine for treating toothache Download PDFInfo
- Publication number
- CN102600287B CN102600287B CN201210077002.1A CN201210077002A CN102600287B CN 102600287 B CN102600287 B CN 102600287B CN 201210077002 A CN201210077002 A CN 201210077002A CN 102600287 B CN102600287 B CN 102600287B
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- CN
- China
- Prior art keywords
- medicine
- parts
- ibuprofen
- toothache
- compound medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000003814 drug Substances 0.000 title claims abstract description 29
- 208000004371 toothache Diseases 0.000 title claims abstract description 13
- 150000001875 compounds Chemical class 0.000 title claims abstract description 10
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 claims abstract description 17
- 229960001680 ibuprofen Drugs 0.000 claims abstract description 17
- 241000628997 Flos Species 0.000 claims description 6
- 229940079593 drug Drugs 0.000 claims description 6
- 239000002775 capsule Substances 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 239000000706 filtrate Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 238000010992 reflux Methods 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 5
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 241000758794 Asarum Species 0.000 abstract 1
- 244000246386 Mentha pulegium Species 0.000 abstract 1
- 235000016257 Mentha pulegium Nutrition 0.000 abstract 1
- 235000004357 Mentha x piperita Nutrition 0.000 abstract 1
- 241000972673 Phellodendron amurense Species 0.000 abstract 1
- 241000246044 Sophora flavescens Species 0.000 abstract 1
- 235000001050 hortel pimenta Nutrition 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 210000004072 lung Anatomy 0.000 description 5
- 230000001717 pathogenic effect Effects 0.000 description 4
- 239000003440 toxic substance Substances 0.000 description 3
- 208000002193 Pain Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 235000008216 herbs Nutrition 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 238000010926 purge Methods 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 231100000167 toxic agent Toxicity 0.000 description 2
- 210000003932 urinary bladder Anatomy 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 206010016807 Fluid retention Diseases 0.000 description 1
- 206010018286 Gingival pain Diseases 0.000 description 1
- 206010018291 Gingival swelling Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 239000003907 antipyretic analgesic agent Substances 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to a compound medicine for treating toothache, in particular to a compound medicine prepared by Chinese medicine and western medicine. The compound medicine is prepared by the following raw materials in parts by weight: 3-10 parts of honeysuckle, 35-45 parts of amur corktree bark, 5-10 parts of asarum, 9-30 parts of fructus gardeniae, 9-15 parts of peppermint, 25-35 parts of sophora flavescens and 8-12 parts of ibuprofen. The compound medicine can be used for treating toothache, has remarkable treatment effect and does not have toxic and side effects.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of toothache, particularly relate to a kind of compound medicine being prepared from by Chinese medicine and western medicine.
Background technology
Toothache is commonly encountered diseases, frequently-occurring disease, in clinical treatment generally with treatment by Chinese herbs or western medicine, the general effect for the treatment of by Chinese herbs is slower, and the time is longer, and patient's the time that bears the pain is longer, and western medicine is generally used analgesic and antibiotic medicine, side effect is large and cure the symptoms, not the disease.
Summary of the invention
In order to address the above problem, the invention provides a kind of compound medicine for the treatment of toothache, both can alleviate fast patient's clinical disease, also can reach treating both the principal and secondary aspects of a disease, thoroughly the object for the treatment of toothache.
Technical scheme of the present invention is as follows
Treat a compound medicine for toothache, by the crude drug of following weight portion, be prepared from: Flos Lonicerae 3-10 part, Cortex Phellodendri 35-45 part, Herba Asari 5-10 part, Fructus Gardeniae 9-30 part, Herba Menthae 9-15 part, Radix Sophorae Flavescentis 25-35 part, ibuprofen 8-12 part.
Preparation method:
Take by weight ratio medicine, get outer all the other Six-elements of ibuprofen, add 8 times of water gaging reflux, extract, 2 times, each 2 hours, filter, merging filtrate, 80 ℃ of concentrating under reduced pressure are to 1.20-1.30, add ibuprofen after cooling, mix, and dry, pulverize, and fill capsule.
The present invention can also utilize modern pharmaceutical technology to adopt other reasonable effective method preparations, also can add the adjuvant pharmaceutically allowing, and makes other suitable dosage forms.
In side, Flos Lonicerae is sweet cold, returns lung, the heart, stomach warp.Function cures mainly heat-clearing and toxic substances removing, dispelling wind and heat pathogens.
Cortex Phellodendri is bitter, cold.Return kidney, urinary bladder channel.Function cures mainly heat clearing and damp drying, and pathogenic fire purging is except steaming, detoxification sore treatment.
Herba Asari is pungent, temperature.GUIXIN, lung, kidney channel.Function cures mainly, expelling wind and cold, and wind-expelling pain-stopping, sensible, warming the lung to resolve fluid-retention.
Fructus Gardeniae is bitter, cold.GUIXIN, lung, tri-jiao channel.Function cures mainly pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.
Herba Menthae is pungent, cool.Return lung, Liver Channel.Function cures mainly dispelling wind and heat pathogens.
Radix Sophorae Flavescentis is bitter, cold.GUIXIN, liver, stomach, large intestine, urinary bladder channel.Function cures mainly heat clearing and damp drying.
Ibuprofen is nonsteroidal antipyretic analgesic, has antipyretic-antalgic antiinflammatory action.
All medicines share above, play altogether clearing away heat-fire, the effect of removing pathogenic heat from blood and toxic substance from the body, the aphtha of the mouth and tongue that is mainly used in being caused by exuberant lung-stomach heat, gingival swelling and pain.
Clinical data
Toothache case 100 examples that the Drug therapy of the embodiment of the present invention 3 preparation causes because of exuberant lung-stomach heat are taken in clinical observation, and obvious effective rate is 70 examples, is effectively 24 examples, and total effective rate is 94%, has statistical significance.In medication process, do not find that this medicine has obvious adverse reaction, test shows this invention treatment toothache, evident in efficacy, has no side effect.
The specific embodiment
Below in conjunction with embodiment, the present invention is described further.
Embodiment 1
Take the crude drug of following weight: Flos Lonicerae 3g, Cortex Phellodendri 35g, Herba Asari 5g, Fructus Gardeniae 9g, Herba Menthae 9g, Radix Sophorae Flavescentis 25g, ibuprofen 8g, get outer all the other Six-elements of ibuprofen, add 8 times of water gaging reflux, extract, 2 times, each 2 hours, filter, merging filtrate, 80 ℃ are evaporated to 1.20, after cooling, add ibuprofen, mix, dry, pulverize, dress capsule, makes into 100.
Embodiment 2
Take the crude drug of following weight parts: Flos Lonicerae 10g, Cortex Phellodendri 45g, Herba Asari 10g, Fructus Gardeniae 30g, Herba Menthae 15g, Radix Sophorae Flavescentis 35g, ibuprofen 12g, get outer all the other Six-elements of ibuprofen, add 8 times of water gaging reflux, extract, 2 times, each 2 hours, filter merging filtrate, 80 ℃ of concentrating under reduced pressure to 1.30, after cooling, add ibuprofen, mix, dry, pulverize, dress capsule, makes into 100.
Embodiment 3
Take the material medicine of following weight portion: Flos Lonicerae 7g, Cortex Phellodendri 40g, Herba Asari 8g, Fructus Gardeniae 18g, Herba Menthae 12g, Radix Sophorae Flavescentis 30g, ibuprofen 10g, get outer all the other Six-elements of ibuprofen, add 8 times of water gaging reflux, extract, 2 times, each 2 hours, filter merging filtrate, 80 ℃ of concentrating under reduced pressure to 1.25, after cooling, add ibuprofen, mix, dry, pulverize, dress capsule, makes into 100.
Claims (1)
1. a compound medicine for the treatment of toothache, is characterized in that, is prepared from: Flos Lonicerae 3-10 part, Cortex Phellodendri 35-45 part, Herba Asari 5-10 part, Fructus Gardeniae 9-30 part, Herba Menthae 9-15 part, Radix Sophorae Flavescentis 25-35 part, ibuprofen 8-12 part by the crude drug of following weight portion;
The recurrence medicine of described treatment toothache is adopted preparation with the following method: take by weight ratio medicine, get outer all the other Six-elements of ibuprofen, add 8 times of water gaging reflux, extract, 2 times, each 2 hours, filter, merging filtrate, 80 ℃ of concentrating under reduced pressure are to 1.20-1.30, add ibuprofen after cooling, mix, dry, pulverize dress capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210077002.1A CN102600287B (en) | 2012-03-22 | 2012-03-22 | Compound medicine for treating toothache |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210077002.1A CN102600287B (en) | 2012-03-22 | 2012-03-22 | Compound medicine for treating toothache |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102600287A CN102600287A (en) | 2012-07-25 |
| CN102600287B true CN102600287B (en) | 2014-02-12 |
Family
ID=46518306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210077002.1A Active CN102600287B (en) | 2012-03-22 | 2012-03-22 | Compound medicine for treating toothache |
Country Status (1)
| Country | Link |
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| CN (1) | CN102600287B (en) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1234389C (en) * | 2003-06-18 | 2006-01-04 | 薛永新 | Chinese traditional medicine for treating oral disease and its preparing process |
| CN1480190A (en) * | 2003-07-10 | 2004-03-10 | 姜延德 | Medication for treating toothache |
| RU2352351C1 (en) * | 2008-01-11 | 2009-04-20 | Сергей Владимирович Сирак | Dental elixir for prevention of teeth caries |
| CN101757216A (en) * | 2008-12-19 | 2010-06-30 | 贾姗姗 | Traditional Chinese medicine for treating toothache |
| CN101444565A (en) * | 2008-12-31 | 2009-06-03 | 内蒙古永业生物技术有限责任公司 | Method for preparing seed of lightyellow sophora oral bacteriostasis dropping liquid |
| CN101647936B (en) * | 2009-07-23 | 2011-07-06 | 杭州六易科技有限公司 | Manufacture method of mouth care lozenges |
| CN102048880A (en) * | 2009-11-05 | 2011-05-11 | 天津开发区太人生物科技有限公司 | Externally applied ointment for adjuvant therapy of pharyngitis and canker sore and preparation method thereof |
| KR20120022493A (en) * | 2010-09-02 | 2012-03-12 | (주)바이오믹스 | An edible composition for prevention and treatment of periodontal disease containing lonicera japonica extract and the manufacturing method |
| CN102139030B (en) * | 2011-03-18 | 2012-08-22 | 王磊 | Oral Chinese herbal preparation for treating gingivitis and preparation method thereof |
-
2012
- 2012-03-22 CN CN201210077002.1A patent/CN102600287B/en active Active
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| Publication number | Publication date |
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| CN102600287A (en) | 2012-07-25 |
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| C14 | Grant of patent or utility model | ||
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Owner name: NANTONG FANGDU HIGH-TECH VENTURE PARK SERVICE CO., Free format text: FORMER OWNER: LI CUIRONG Effective date: 20140417 |
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| C41 | Transfer of patent application or patent right or utility model | ||
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Free format text: CORRECT: ADDRESS; FROM: 250012 JINAN, SHANDONG PROVINCE TO: 226112 NANTONG, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20140417 Address after: 226112, Jiangsu, Nantong Haimen town Sanxing village 15 groups Patentee after: Nantong Textile Science and Technology Pioneer Park Service Co.,Ltd. Address before: 250012 Department of oral surgery, Qilu Hospital,, 107 west Wenhua Road, Lixia District, Shandong, Ji'nan Patentee before: Li Cuirong |
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Address after: 226112, Jiangsu, Nantong Haimen town Sanxing village 15 groups Patentee after: Nantong textile Capital Management Co.,Ltd. Address before: 226112, Jiangsu, Nantong Haimen town Sanxing village 15 groups Patentee before: Nantong Textile Science and Technology Pioneer Park Service Co.,Ltd. |
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| CP01 | Change in the name or title of a patent holder | ||
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| TR01 | Transfer of patent right |
Effective date of registration: 20200619 Address after: Sanxing Zhen Nan Cun, Haimen City, Nantong City, Jiangsu Province Patentee after: Jiangsu Dieshiqiao Investment Co.,Ltd. Address before: 226112, Jiangsu, Nantong Haimen town Sanxing village 15 groups Patentee before: Nantong textile Capital Management Co.,Ltd. |