CN102631554B - Traditional Chinese medicinal composition for treating periodontitis - Google Patents
Traditional Chinese medicinal composition for treating periodontitis Download PDFInfo
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- CN102631554B CN102631554B CN2012101376200A CN201210137620A CN102631554B CN 102631554 B CN102631554 B CN 102631554B CN 2012101376200 A CN2012101376200 A CN 2012101376200A CN 201210137620 A CN201210137620 A CN 201210137620A CN 102631554 B CN102631554 B CN 102631554B
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Abstract
The invention discloses a Chinese medicinal composition for treating periodontitis. The Chinese medicinal composition is prepared from raw gypsum, dahurian patrinia herbs, Japanese honeysuckle stems, Indian Iphigenia bulbs, roots of rehmannia, cortex moutan, coastal glehnia roots, platycodon grandiflorum, Manchurian wild gingers and astragalus. The Chinese medicinal composition can be clinically used for treating the periodontitis.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of periodontitis.
Background technology
Periodontitis is the chronic destructive disease of invading gingiva and periodontal support tissue, and its principal character is the inflammation of periodontal pocket formation and bag wall, frontal resorption and odontoseisis, and the companion sees the symptoms such as red swelling of gingiva is hemorrhage simultaneously.Treatment periodontitis, doctor trained in Western medicine adopt Perorally administrable antimicrobial anti-inflammation drugs and local periodontal surgery and local medicine-feeding etc. more.If alone anti-inflammation drugs, usually can not obtain gratifying effect, especially systemic administration can produce more untoward reaction, as Effect of Oral Metronidazole, can cause the symptoms such as erythra, anaphylaxis, GI irritation, nausea and vomiting.Through inventor's long-term practice, draw, Chinese medicine is controlled periodontitis and is had better effect, obtains good effect.
Summary of the invention
The Chinese medicine composition of the treatment periodontitis that the object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Gypsum Fibrosum, Herba Patriniae, Caulis Lonicerae, Pseudobulbus Cremastrae Seu Pleiones, the Radix Rehmanniae, Cortex Moutan, Radix Glehniae, Radix Platycodonis, Herba Asari, the Radix Astragali according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention and make Gypsum Fibrosum 20-40 part, Herba Patriniae 10-30 part, Caulis Lonicerae 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 10-30 part, Radix Rehmanniae 10-20 part, Cortex Moutan 10-20 part, Radix Glehniae 10-20 part, Radix Platycodonis 10-20 part, Herba Asari 8-15 part, Radix Astragali 8-15 part by following raw material medicaments.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 30 parts of Gypsum Fibrosum, 20 parts of Herba Patriniae, 20 parts of Caulis Loniceraes, 20 parts of Pseudobulbus Cremastrae Seu Pleioness, 15 parts, the Radix Rehmanniae, 15 parts of Cortex Moutans, 15 parts of Radix Glehniaes, 15 parts of Radix Platycodoniss, 10 parts of Herba Asaris, 10 parts of the Radixs Astragali.
The pharmacological action of Chinese medicine of the present invention is as follows:
Gypsum Fibrosum: hot, sweet, cold, nontoxic.Attach to the lung and stomach meridians.Expelling pathogenic factors from muscles for clearing heat, relieving restlessness is quenched the thirst.For the calentura high fever, do not move back vexed coma, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach-fire headache, toothache due to stomach-fire, aphtha of the mouth and tongue, the burning hot wound of soup etc.
Herba Patriniae: hot, bitter, be slightly cold, return stomach, large intestine, Liver Channel.Heat-clearing and toxic substances removing, the eliminating carbuncle evacuation of pus.For abdominalgia with intestinal abscess, carbuncle sore tumefacting virus.
Caulis Lonicerae: sweet, cold.GUIXIN, lung meridian.Heat-clearing and toxic substances removing, dredging collateral.For epidemic febrile disease heating, ulcer sore pain, acute appendicitis, acute mastitis, toxic-heat and blood stasis, rheumatic arthralgia etc.
Pseudobulbus Cremastrae Seu Pleiones: sweet, micro-suffering, cold in nature.Return liver, stomach, lung meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For the carbuncle malignant boil, scrofula tuberculosis, pharyngalgia sore throat, Serpentis, insect bite wound etc.
The Radix Rehmanniae: sweet, bitter, cold.GUIXIN, liver, kidney channel.Clearing away heat and cooling blood, promote the production of body fluid and moisturize.For acute calenture, excessive thirst is hindered in Tianjin, the haematemesis of bleeding due to blood-heat, epistaxis, metrorrhagia, aphtha of the mouth and tongue, laryngopharynx swelling and pain, consumptive fever cough, traumatic pain, carbuncle etc.
Cortex Moutan: arduous, cool, be slightly cold.GUIXIN, sweet, kidney, lung meridian.Heat clearing away, promoting blood circulation to remove blood stasis.For the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, tell nosebleed, deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus, fall and flutter the pain of injury, rheumatism pyretic arthralgia etc.
Radix Glehniae: sweet, micro-hardship, be slightly cold, attach to the lung and stomach meridians.Nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.For the lung-heat type cough of deficiency of lung-YIN, the few expectorant of dry cough, deficiency of stomach-YIN or thermal burn stomach-Yin, the thirsty and dry pharynx of deficiency of body fluid etc.
Radix Platycodonis: bitter, hot, flat.Attach to the lung and stomach meridians.Lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus.For cough with copious phlegm, laryngopharynx swelling and pain, lung abscess vomiting pus, the full hypochondriac pain of born of the same parents, dysentery stomachache etc.
Herba Asari: suffering, temperature, mild toxicity.Return lung, kidney, the heart, liver but, spleen channel.Cold expelling dispels the wind, pain relieving, warming the lung to resolve fluid-retention.For exterior syndrome due to wind-cold, headache, toothache, rheumatic arthralgia etc.
The Radix Astragali: sweet, warm, return lung, spleen channel.Benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening.For diarrhea due to hypofunction of the spleen, wait the card of all Qi and blood deficiencies.
Periodontitis belongs to the traditional Chinese medical science " gingival atrophy " category, and sick position is at gums, close with the Zang-Fu relationship such as stomach spleen kidney large intestine, and surfeit is pungent processs rich, excessive drinking surfeit or exhaustion due to sexual indulgence and too wait can cause on stomach-fire and steam, the tooth that the disappears gum that burns; Or deficiency of kidney-YIN, hyperactivity of deficient fire, burning gingiva and sending out is primary disease; Prolonged illness causes QI and blood deficiency, and tooth loses and to moisten fosterly, and tooth loses moist and sees that teeth are loosening, the diseases such as gingival atrophy.Gypsum Fibrosum, Herba Patriniae, Caulis Lonicerae, Pseudobulbus Cremastrae Seu Pleiones dispelling wind to relieve the exterior syndrome, clearing away heat and cooling blood in the present invention, the Radix Rehmanniae, Cortex Moutan, Radix Glehniae, Radix Platycodonis kidney tonifying tonifying the lung, removing heat from blood yin nourishing, Herba Asari, Radix Angelicae Dahuricae wind-expelling pain-stopping, Radix Astragali warming the kidney to activate YANG, benefiting QI for strengthening the superficies.Through clinical practice, find that periodontitis is had to unique curative effect.
Chinese medicine composition of the present invention was in 2006 to 2011 the routine patients of clinical observation periodontitis 120, and clinical report is as follows:
1, physical data
In 120 routine patients, age 15-63 year, the course of disease is many at 20 days to 2 years, 43 years old mean age.
2, diagnostic criteria
" traditional Chinese medical science disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:
Gingiva presents inflammation in various degree, as red swelling of gingiva, hemorrhage, the gingiva pyorrhea, stippling disappearance etc., periodontal pocket forms, pyorrhea in bag, in various degree loosening appears in tooth, suffer from tooth around can be checked through paathogenic factor, as bacterial plaque, tartar, food impaction, traumatic gritting one's teeth, close and bad dummy etc., x-ray shows that alveolar bone has absorbing phenomenon in various degree.
3, Therapeutic Method
3.1 prescription: Gypsum Fibrosum 30g, Herba Patriniae 20g, Caulis Lonicerae 20g, Pseudobulbus Cremastrae Seu Pleiones 20g, Radix Rehmanniae 15g, Cortex Moutan 15g, Radix Glehniae 15g, Radix Platycodonis 15g, Herba Asari 10g, Radix Astragali 10g.
3.2 method of preparation and use: said medicine technique is routinely made decoction, and 1 dose of every day, every day 2 times, 5 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":
Recovery from illness: inflammation disappears, and gingival swelling and pain disappears, and without inflammatory exudate, periodontal pocket disappears or shoals, and frontal resorption is silent oscillation, and tooth mobility II0 turns I0, and masticatory function is improved, and General Symptoms is removed;
Produce effects: inflammation disappears, and gingival swelling and pain disappears substantially, and substantially without inflammatory exudate, periodontal pocket shoals, and the frontal resorption situation is stable, and tooth mobility alleviates, and masticatory function makes moderate progress, and General Symptoms alleviates;
Invalid: symptom, sign slightly alleviate or the person of not being any change.
4.2 result: in 120 routine patients, clinical cure 83 examples (69.2%), produce effects 31 examples (25.8%), invalid 6 examples (5%), total effective rate is 95%.
5, model case
5.1 grandson, the man, 42 years old, the red swelling of gingiva of visiting, touch hemorrhage, the lower front tooth gingival enlargement, the II degree touched is loosening, the halitosis of newss, dry stool greatly, red tongue, yellow fur is thick.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and continues to take 3 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.
5.2 Liu, the female, 28 years old, red swelling of gingiva hyperemia, that touches is hemorrhage, depth of pocket 3mm, pyorrhea, odontoseisis, knocking pain, implication heat is smelly, constipation, yellowish or reddish urine.Take medicine of the present invention, 1 dose of every day, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment, and following this embodiment does not only limit the present invention be used to the present invention is described.
Embodiment 1, and a kind of Chinese medicine composition for the treatment of periodontitis is to be made by Gypsum Fibrosum 20g, Herba Patriniae 10g, Caulis Lonicerae 10g, Pseudobulbus Cremastrae Seu Pleiones 10g, Radix Rehmanniae 10g, Cortex Moutan 10g, Radix Glehniae 10g, Radix Platycodonis 10g, Herba Asari 8g, Radix Astragali 8g.
Embodiment 2, and a kind of Chinese medicine composition for the treatment of periodontitis is to be made by Gypsum Fibrosum 30g, Herba Patriniae 20g, Caulis Lonicerae 20g, Pseudobulbus Cremastrae Seu Pleiones 20g, Radix Rehmanniae 15g, Cortex Moutan 15g, Radix Glehniae 15g, Radix Platycodonis 15g, Herba Asari 10g, Radix Astragali 10g.
Embodiment 3, and a kind of Chinese medicine composition for the treatment of periodontitis is to be made by Gypsum Fibrosum 40g, Herba Patriniae 30g, Caulis Lonicerae 30g, Pseudobulbus Cremastrae Seu Pleiones 30g, Radix Rehmanniae 20g, Cortex Moutan 20g, Radix Glehniae 20g, Radix Platycodonis 20g, Herba Asari 15g, Radix Astragali 15g.
Claims (2)
1. Chinese medicine composition for the treatment of periodontitis is characterized in that it is to be made by following raw material medicaments:
Gypsum Fibrosum 20-40 part, Herba Patriniae 10-30 part, Caulis Lonicerae 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 10-30 part, Radix Rehmanniae 10-20 part, Cortex Moutan 10-20 part, Radix Glehniae 10-20 part, Radix Platycodonis 10-20 part, Herba Asari 8-15 part, Radix Astragali 8-15 part.
2. Chinese medicine composition according to claim 1 is characterized in that it is to be made by following raw material medicaments:
30 parts of Gypsum Fibrosum, 20 parts of Herba Patriniae, 20 parts of Caulis Loniceraes, 20 parts of Pseudobulbus Cremastrae Seu Pleioness, 15 parts, the Radix Rehmanniae, 15 parts of Cortex Moutans, 15 parts of Radix Glehniaes, 15 parts of Radix Platycodoniss, 10 parts of Herba Asaris, 10 parts of the Radixs Astragali.
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| CN102178833A (en) * | 2011-01-14 | 2011-09-14 | 丁盘武 | Medicine for treating toothache |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102178833A (en) * | 2011-01-14 | 2011-09-14 | 丁盘武 | Medicine for treating toothache |
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| 尹冰等.中西医结合治疗牙周炎临床分析.《吉林大学学报(医学版)》.2007,(第04期),715. |
| 牙周合剂的制备与临床应用;赵满靖;《中国中医药科技》;20080520(第03期) * |
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Effective date of registration: 20140909 Address after: 226200 chemical industry park, Nantong, Jiangsu, Qidong Patentee after: NANTONG HONGCI PHARMACEUTICAL CO., LTD. Address before: 262500 Shandong province Qingzhou City Linglong Mountain Road No. 3888 Qingzhou Invalides hospital Patentee before: Hao Kaijun |