CN103623196A - Traditional Chinese medicine composition for treating yin-deficiency and fire-excess type periodontitis - Google Patents

Traditional Chinese medicine composition for treating yin-deficiency and fire-excess type periodontitis Download PDF

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CN103623196A
CN103623196A CN201310725018.3A CN201310725018A CN103623196A CN 103623196 A CN103623196 A CN 103623196A CN 201310725018 A CN201310725018 A CN 201310725018A CN 103623196 A CN103623196 A CN 103623196A
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chinese medicine
medicine composition
deficiency
yin
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CN103623196B (en
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韩月红
李文东
崔绍俭
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Qidong Feng Wu Agricultural Cooperatives
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Abstract

The invention discloses a traditional Chinese medicine composition for treating yin-deficiency and fire-excess type periodontitis. The traditional Chinese medicine composition is prepared from garcinia multiflora bark, laricifomes officinalis, rhizoma anemarrhenae, barberry, herba andrographitis, bulbophyllum kwangtungense schltr, cape jasmine leaves, polygonum multiflorum, sweet wormwood and taurodont. The traditional Chinese medicine composition can be clinically used for treating the yin-deficiency and fire-excess type periodontitis.

Description

A kind of Chinese medicine composition for the treatment of type of hyperactivity of fire caused by deficiency of YIN periodontitis
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of type of hyperactivity of fire caused by deficiency of YIN periodontitis.
Background technology
Periodontitis is one of department of stomatology common disease, often with general malaise symptom, affects patient's feed, language, daily life, and its sickness rate is always high clinically.The principal character of periodontitis is that periodontal pocket forms and inflammation, frontal resorption and the tooth of bag wall become flexible gradually, and it is the main cause that causes adult's loss of tooth.Doctor trained in Western medicine traditional remedies is to use metronidazole, penicillin, can comparatively fast eliminate acute inflammation symptom, but its untoward reaction is also apparent, as anaphylaxis, and erythra, GI irritation disease.Through inventor's long-term practice, draw, Chinese medicine is controlled type of hyperactivity of fire caused by deficiency of YIN periodontitis and is had better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide the Chinese medicine composition of the treatment type of hyperactivity of fire caused by deficiency of YIN periodontitis that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt skin of Fructus Garciniae oblongifoliae, bitter white hoof, the Rhizoma Anemarrhenae, Radix Berberidis, Herba Andrographis, the blue bean of wide stone, Folium Gardeniae, Radix Polygoni Multiflori, Herba Artemisiae Annuae, Dens Bovis seu Bubali according to certain compatibility requirement, through being processed into.
Preparing Chinese medicine composition of the present invention is made by following raw material medicaments: skin of Fructus Garciniae oblongifoliae 30-40 part, bitter white hoof 20-30 part, Rhizoma Anemarrhenae 20-30 part, Radix Berberidis 15-25 part, Herba Andrographis 15-25 part, the blue bean 15-25 of wide stone part, Folium Gardeniae 15-25 part, Radix Polygoni Multiflori 15-25 part, Herba Artemisiae Annuae 8-15 part, Dens Bovis seu Bubali 3-5 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 35 parts of skin of Fructus Garciniae oblongifoliae, 25 parts of bitter white hoof, 25 parts of the Rhizoma Anemarrhenaes, 20 parts of Radix Berberidis, 20 parts of Herba Andrographis, 20 parts of the blue beans of wide stone, 20 parts of Folium Gardeniae, 20 parts of Radix Polygoni Multiflori, 12 parts of Herba Artemisiae Annuaes, 4 parts of Dens Bovis seu Bubali.
The pharmacological action of Chinese medicine of the present invention is as follows:
Skin of Fructus Garciniae oblongifoliae: bitter, acid, cool.Heat-clearing and toxic substances removing, convergence granulation promoting.Clinical in peptic ulcer, enteritis, stomatitis, periodontitis, ulcer of the lower limb, eczema, the diseases such as scald.
Bitter white hoof: sweet, bitter, warm, nontoxic.Relieving cough and asthma, expelling wind and removing dampness, reducing swelling and alleviating pain, diuresis, antidotes against snake bite.Clinical in cough, asthma, chronic rheumatic arthritis, stomachache, laryngopharynx swelling and pain, periodontitis, lithangiuria, edema, the diseases such as venom.
The Rhizoma Anemarrhenae: sweet, bitter, cold, return lung, stomach, kidney channel.Clearing away heat-fire is nourshing Yin and drynsessmoistening prescription.For calentura excessive thirst, cough due to lung-heat.
Radix Berberidis: bitter, cold.Return liver, stomach, large intestine channel.Heat clearing away, dampness, eliminating fire and detoxication.Cure mainly dysentery due to damp-heat profit, diarrhoea, jaundice, eczema, skin infection, aphtha, conjunctival congestion, pharyngalgia.
Herba Andrographis: bitter, cold.GUIXIN, lung, large intestine, urinary bladder channel.Heat-clearing and toxic substances removing, pathogenic fire purging, dampness.Clinical in anemopyretic cold, epidemic febrile disease heating, cough due to lung-heat, pertussis, lung abscess, laryngopharynx swelling and pain, jaundice due to damp-heat, stranguria, erysipelas, skin infection carbuncle, eczema, venom etc.
The blue bean of wide stone: sweet, light, cool.Heat clearing away, YIN nourishing, detumescence.For wind heat pharyngalgia, cough due to lung-heat, yin asthenia generating intrinsic heat, calentura is thirsty, rheumatic arthralgia, traumatic injury, mastitis etc.
Folium Gardeniae: bitter, puckery, cold.Return lung, liver, kidney channel.Promoting blood circulation and detumescence, heat-clearing and toxic substances removing.For traumatic injury, furunculosis, hemorrhoid, primary sore etc.
Radix Polygoni Multiflori: bitter, sweet, puckery, warm.Return liver, kidney channel.Nourishing the blood and yin, loosening bowel to relieve constipation, preventing the attack (or recurrence) of malaria, dispels the wind, removing toxic substances.Clinical in blood deficiency Light-headedness, cardiopalmus, insomnia, the soreness of the waist and knees of the hepatic and renal YIN deficiency, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body is empty, rubella pruritus, carbuncle sore, scrofula, the diseases such as hemorrhoid.
Herba Artemisiae Annuae: bitter, micro-pungent, cold.Return liver, gallbladder meridian.Heat clearing away, expelling summer-heat, except steaming, preventing the attack (or recurrence) of malaria.For summer-heat, heat-damp in summer, fever due to yin deficiency, malaria, the diseases such as jaundice.
Dens Bovis seu Bubali: puckery, cool.Pericardium channel.Relieving convulsion, teeth consolidating, sore.Clinically for tooth, shake the diseases such as carbuncle on the back malignant boil.
TCM Document has detailed description to the cause of disease of periodontal disease, pathology, symptom, treatment etc., is referred to as gingival atrophy, bleeding from the gum, and dental bed swells and ache, and tooth shakes etc.Skin of Fructus Garciniae oblongifoliae heat-clearing and toxic substances removing in the present invention, convergence granulation promoting, is monarch drug, bitter white hoof reducing swelling and alleviating pain, Rhizoma Anemarrhenae clearing away heat-fire, nourshing Yin and drynsessmoistening prescription, is ministerial drug, Radix Berberidis heat clearing away, eliminating fire and detoxication, Herba Andrographis heat-clearing and toxic substances removing, pathogenic fire purging, the blue bean heat clearing away of wide stone, YIN nourishing, detumescence, Folium Gardeniae promoting blood circulation and detumescence, heat-clearing and toxic substances removing, Radix Polygoni Multiflori nourishing the blood and yin, Herba Artemisiae Annuae heat clearing away, Dens Bovis seu Bubali teeth consolidating.All medicines share, and play altogether heat-clearing and toxic substances removing, nourishing YIN to lower pathogenic fire, detumescence teeth consolidating.Through clinical practice, find that type of hyperactivity of fire caused by deficiency of YIN periodontitis is had to unique curative effect, reach the object for the treatment of type of hyperactivity of fire caused by deficiency of YIN periodontitis.
Chinese medicine composition of the present invention was in 2010 to 2013 clinical observation type of hyperactivity of fire caused by deficiency of YIN periodontitis 87 routine patients, and clinical report is as follows:
1, physical data
In 87 routine patients, age 22-61 year, the course of disease is many at 20 days to 1 year, 41 years old mean age.
2, diagnostic criteria
The < < traditional Chinese medical science disease Standardization of diagnosis and curative effect > > issuing according to State Administration of Traditional Chinese Medicine:
Gingiva presents inflammation in various degree, as red swelling of gingiva, hemorrhage, gingiva pyorrhea, stippling disappearance etc., periodontal pocket forms, pyorrhea in bag, there is in various degree loosening in tooth, the surrounding of suffering from tooth can be checked through paathogenic factor, as bacterial plaque, tartar, food impaction, traumatic gritting one's teeth, closes and bad dummy etc., and x-ray shows that alveolar bone has absorbing phenomenon in various degree.Type of hyperactivity of fire caused by deficiency of YIN periodontal disease is shown in that symptom is shown in that to have gingiva slight red and swollen or light red, gingival atrophy, tooth or dental caries dull pain, odontoseisis, the visible diastema broadening of x-ray, xerostomia is wish drink not, have a dizzy spell, Hiccough and deaf, soreness of the waist and knees, dysphoria with feverish sensation in the chest palms and soles; oliguria with yellow urine; defecate partially dry, the few tongue of red tongue, thready and rapid pulse.
3, Therapeutic Method
3.1 prescriptions: skin of Fructus Garciniae oblongifoliae 35g, bitter white hoof 25g, Rhizoma Anemarrhenae 25g, Radix Berberidis 20g, Herba Andrographis 20g, the blue bean 20g of wide stone, Folium Gardeniae 20g, Radix Polygoni Multiflori 20g, Herba Artemisiae Annuae 12g, Dens Bovis seu Bubali 4g.
3.2 methods of preparation and use: said medicine routinely technique is made decoction, every day 2 times, 10 days were 1 course for the treatment of at 1 dose of every day.
4, therapeutic outcome:
4.1 formulate with reference to < < Chinese medicine Clinical Researches of New Drugs guideline > >:
Recovery from illness: inflammation disappears, gingival swelling and pain disappears, and without inflammatory exudate, periodontal pocket disappears or shoal (<4 mm), and frontal resorption is silent oscillation, and tooth mobility II0 turns I0, and masticatory function is improved, and General Symptoms is removed;
Effective: inflammation disappears, gingival swelling and pain disappears substantially, and substantially without inflammatory exudate, periodontal pocket shoals, and frontal resorption situation is stable, and tooth mobility alleviates, and masticatory function makes moderate progress, and General Symptoms alleviates;
Invalid: symptom, sign slightly alleviate or the person of not being any change.
4.2 results: in 87 routine patients, clinical cure 45 examples (51.7%), effective 31 examples (35.6%), invalid 11 examples (12.7%), total effective rate is 87.3%.
5, model case
5.1 Lee, man, 31 years old, the red swelling of gingiva of visiting, touch hemorrhage, lower front tooth gingival enlargement, the II degree touching is loosening, the halitosis of news, has a dizzy spell, Hiccough and deaf, soreness of the waist and knees, dysphoria with feverish sensation in the chest palms and soles, oliguria with yellow urine, thready and rapid pulse.Take medicine of the present invention, treat 1 course for the treatment of, symptom obviously alleviates, and continues to take 3 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.
5.2 Zhao, female, 42 years old, red swelling of gingiva was congested, and that touches is hemorrhage, depth of pocket 3mm, pyorrhea, odontoseisis, knocking pain, implication heat is smelly, constipation, yellowish or reddish urine, the few tongue of red tongue.Take medicine of the present invention, 1 dose of every day, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.
Embodiment 1, and a kind of Chinese medicine composition for the treatment of type of hyperactivity of fire caused by deficiency of YIN periodontitis is to be made by skin of Fructus Garciniae oblongifoliae 30g, bitter white hoof 20g, Rhizoma Anemarrhenae 20g, Radix Berberidis 15g, Herba Andrographis 15g, the blue bean 15g of wide stone, Folium Gardeniae 15g, Radix Polygoni Multiflori 15g, Herba Artemisiae Annuae 8g, Dens Bovis seu Bubali 3g.
Embodiment 2, treating a Chinese medicine composition for type of hyperactivity of fire caused by deficiency of YIN periodontitis, is to be made by skin of Fructus Garciniae oblongifoliae 35g, bitter white hoof 25g, Rhizoma Anemarrhenae 25g, Radix Berberidis 20g, Herba Andrographis 20g, the blue bean 20g of wide stone, Folium Gardeniae 20g, Radix Polygoni Multiflori 20g, Herba Artemisiae Annuae 12g, Dens Bovis seu Bubali 4g.
Embodiment 3, treating a Chinese medicine composition for type of hyperactivity of fire caused by deficiency of YIN periodontitis, is to be made by skin of Fructus Garciniae oblongifoliae 40g, bitter white hoof 30g, Rhizoma Anemarrhenae 30g, Radix Berberidis 25g, Herba Andrographis 25g, the blue bean 25g of wide stone, Folium Gardeniae 25g, Radix Polygoni Multiflori 25g, Herba Artemisiae Annuae 15g, Dens Bovis seu Bubali 5g.

Claims (2)

1. treat a Chinese medicine composition for type of hyperactivity of fire caused by deficiency of YIN periodontitis, it is characterized in that it is to be made by following raw material medicaments:
Skin of Fructus Garciniae oblongifoliae 30-40 part, bitter white hoof 20-30 part, Rhizoma Anemarrhenae 20-30 part, Radix Berberidis 15-25 part, Herba Andrographis 15-25 part, the blue bean 15-25 of wide stone part, Folium Gardeniae 15-25 part, Radix Polygoni Multiflori 15-25 part, Herba Artemisiae Annuae 8-15 part, Dens Bovis seu Bubali 3-5 part.
2. Chinese medicine composition according to claim 1, is characterized in that it is to be made by following raw material medicaments:
35 parts of skin of Fructus Garciniae oblongifoliae, 25 parts of bitter white hoof, 25 parts of the Rhizoma Anemarrhenaes, 20 parts of Radix Berberidis, 20 parts of Herba Andrographis, 20 parts of the blue beans of wide stone, 20 parts of Folium Gardeniae, 20 parts of Radix Polygoni Multiflori, 12 parts of Herba Artemisiae Annuaes, 4 parts of Dens Bovis seu Bubali.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104288488A (en) * 2014-09-26 2015-01-21 江苏奇力康皮肤药业有限公司 Medicine for treating swelling and aching of gum and preparation method of medicine
CN105535277A (en) * 2016-01-19 2016-05-04 中山百鸥医药科技有限公司 Traditional Chinese herbal medicine decoction for treating periodontitis and preparation method of traditional Chinese herbal medicine decoction

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104288488A (en) * 2014-09-26 2015-01-21 江苏奇力康皮肤药业有限公司 Medicine for treating swelling and aching of gum and preparation method of medicine
CN105535277A (en) * 2016-01-19 2016-05-04 中山百鸥医药科技有限公司 Traditional Chinese herbal medicine decoction for treating periodontitis and preparation method of traditional Chinese herbal medicine decoction

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Address after: The 9 group and the Yin Yang Zhen Feng Cun Qidong, Jiangsu city of Nantong province 226200

Patentee after: Qidong Feng Wu agricultural cooperatives

Address before: The 262600 Shandong city of Weifang province Linqu County Road No. 21 people's Hospital of Linqu County

Patentee before: Han Yuehong

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