CN102872346A - Traditional Chinese medicine composition for treating xerostomia - Google Patents

Traditional Chinese medicine composition for treating xerostomia Download PDF

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CN102872346A
CN102872346A CN2012103290454A CN201210329045A CN102872346A CN 102872346 A CN102872346 A CN 102872346A CN 2012103290454 A CN2012103290454 A CN 2012103290454A CN 201210329045 A CN201210329045 A CN 201210329045A CN 102872346 A CN102872346 A CN 102872346A
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radix
chinese medicine
medicine composition
traditional chinese
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王先忠
董艳丽
王军红
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王先忠
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Abstract

The invention relates to a traditional Chinese medicine composition for treating xerostomia, which is composed of the following traditional Chinese medicine raw materials in parts by weight: 5 to 25 parts of fructus lycii, 5 to 25 parts of radix rehmanniae, 5 to 25 parts of rehmannia glutinosa, 5 to 20 parts of cortex moutan radicis, 10 to 30 parts of rhizoma anemarrhenae, 10 to 40 parts of radix ophiopogonis, 10 to 40 parts of radix scrophulariae, 10 to 30 parts of radix adenophorae, 10 to 30 parts of taraxacum, 5 to 25 parts of herba ecliptae, 5 to 25 parts of fructus ligustri lucidi, 5 to 25 parts of mrlberrt fruit, 5 to 25 parts of dendrobium nobile, 5 to 25 parts of radix polygonati officinalis, 5 to 25 parts of cornus officinalis, 5 to 25 parts of radix asparagi and 5 to 25 parts of flos chrysanthemi. The traditional Chinese medicine composition provided by the invention has the effects on nourishing the liver and the kidney, clearing heat and moistening dryness, nourishing and replenishing blood and helping produce saliva and slake thirst, and the efficacy of the traditional Chinese medicine composition on treatment of xerostomia is remarkable and the effect is reliable. The traditional Chinese medicine composition provided by the invention is wide in component medicinal herbs resource, simple to prepare, moderate in property of the medicine, and free from toxic and side effects.

Description

A kind of Chinese medicine composition for the treatment of xerostomia
Technical field
The present invention relates to a kind of medicinal preparation of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of xerostomia.
Background technology
Xerostomia is the caused a kind of symptom of aptyalism in the oral cavity.The minimizing of salivation in the oral cavity causes the variation of local environment in the oral cavity; The tooth body is owing to lacking self-cleaning action, and the antibacterial efficacy that saliva essence has descends, and easily causes rampant caries or periodontal disease; Oral mucosa is dry, atrophy.Deep red tongue, tongue fur reduces, and rill appears in back, and burn feeling is arranged.Most xerostomia patients' the sense of taste is affected, and can affect the function of whole digestive system.Xerostomia is higher with old people's sickness rate clinically.The treatment of xerostomia can only symptomatic treatment clinically, to alleviate the xerostomia symptom as main.For example, be drug-induced, can change prescription or adjust dosage; Salivary gland occurs unusually in this way, but still can salivate, and can take the medicine that promotes salivation; Can't eliminate the reason that causes xerostomia in this way, can use the oral cavity wetting agent, such as saliva substitute etc.
The traditional Chinese medical science thinks, xerostomia is many to be caused by the hepatic and renal YIN deficiency, body fluid cannot flow upwards, or by consumption of body fluid caused by intense heat, fry in shallow oil due to the body fluid that burns.
According to theory of Chinese medical science, for the pathogeny of xerostomia, take nourishing the liver and kidney, QI invigorating moisturize, clearing away heat and promoting production of body fluid is as the rule for the treatment of, carries out dialectical composition of prescription, to reach the healing purpose.
Summary of the invention
Can only relief of symptoms and the deficiency that can not effect a permanent cure in order to overcome the existing xerostomia for the treatment of clinically, the invention provides a kind ofly prepare conveniently, cost is low, evident in efficacy, the Chinese medicine composition of short treating period, the treatment xerostomia that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition of xerostomia is characterized in that: its raw material of Chinese medicine by following weight portion forms: 5~25 parts of Fructus Lyciis, 5~25 parts in the Radix Rehmanniae, 5~25 parts in Radix Rehmanniae Preparata, 5~20 parts of Cortex Moutans, 10~30 parts of the Rhizoma Anemarrhenaes, 10~40 parts of Radix Ophiopogonis, 10~40 parts of Radix Scrophulariaes, 10~30 parts of Radix Adenophorae (Radix Glehniae), 10~30 parts of Herba Taraxacis, 5~25 parts of Herba Ecliptaes, 5~25 parts of Fructus Ligustri Lucidi, 5~25 parts of Fructus Mori, 5~25 parts of Herba Dendrobiis, 5~25 parts of Rhizoma Polygonati Odorati, 5~25 parts of Fructus Corni, 5~25 parts of Radix Asparagi, 5~25 parts of Flos Chrysanthemis.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition of xerostomia is characterized in that: its raw material of Chinese medicine by following weight portion forms: 15 parts of Fructus Lyciis, 15 parts in the Radix Rehmanniae, 15 parts in Radix Rehmanniae Preparata, 10 parts of Cortex Moutans, 20 parts of the Rhizoma Anemarrhenaes, 30 parts of Radix Ophiopogonis, 30 parts of Radix Scrophulariaes, 20 parts of Radix Adenophorae (Radix Glehniae), 20 parts of Herba Taraxacis, 15 parts of Herba Ecliptaes, 12 parts of Fructus Ligustri Lucidi, 15 parts of Fructus Mori, 12 parts of Herba Dendrobiis, 15 parts of Rhizoma Polygonati Odorati, 15 parts of Fructus Corni, 15 parts of Radix Asparagi, 15 parts of Flos Chrysanthemis.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription, treating both the principal and secondary aspects of a disease.In Chinese medicine composition of the present invention, Fructus Lycii has the effect of nourishing the liver and kidney, nourishing the liver to improve visual acuity, strengthening the body resistance, spermatogenesis benefit marrow, enriching yin and nourishing kidney, benefiting vital QI for tranquillizing; The Radix Rehmanniae has the effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, pain relieving regulating menstruation; Radix Rehmanniae Preparata has the effect of the yin nourishing of enriching blood, life essence-filling, marrow-benefitting; Cortex Moutan has the effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; The Rhizoma Anemarrhenae has clearing away heat-fire, the effect of promoting the production of body fluid and moisturizing; Has the effect that YIN nourishing and the production of body fluid promoting, lung moistening clear away heart-fire Radix Ophiopogonis; Radix Scrophulariae has the effect of removing heat from blood YIN nourishing, eliminating fire and detoxication; Radix Adenophorae (Radix Glehniae) has the effect that nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid, QI invigorating are reduced phlegm; Herba Taraxaci has the effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Herba Ecliptae has the effect of liver-nourishing kidney-boosting, cooling blood for hemostasis; Fructus Ligustri Lucidi has the merit that nourishing the liver and kidney, tonifying YIN nourish blood; Fructus Mori has nourishing YIN and supplementing blood, the effect of the intestine moistening of promoting the production of body fluid; Herba Dendrobii has the effect of reinforcing stomach reg fluid, nourishing YIN and clearing away heat; Rhizoma Polygonati Odorati has the effect of nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst; Fructus Corni has the effect of liver and kidney tonifying, essence astringing and desertion stemming; That Radix Asparagi has is nourshing Yin and drynsessmoistening prescription, the effect of lung heat clearing pathogenic fire reducing; Flos Chrysanthemi has that dispelling wind and heat pathogens, suppressing the hyperactive liver make eye bright, the effect of heat-clearing and toxic substances removing.This compositions is coordinated mutually, combined effect, play altogether nourishing the liver and kidney, clearing heat and moistening dryness, nourish blood enrich blood, the effect of promoting the production of body fluid to quench thirst.The component of the present composition all adopts natural raw material of Chinese medicine, and preparation is simple, and the medicine source is wide, and used raw material of Chinese medicine cost is low.
The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the usefulness that is decocted in water for oral dose.Through the clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, toxic and side effects do not occur, and total effective rate reaches 95.5%, cure rate 70%.
The specific embodiment
The present invention will be further described below in conjunction with embodiment.
Embodiment 1
A kind of Chinese medicine composition of xerostomia, its raw material of Chinese medicine by following weight portion forms: Fructus Lycii 15g, Radix Rehmanniae 15g, Radix Rehmanniae Preparata 15g, Cortex Moutan 10g, Rhizoma Anemarrhenae 20g, Radix Ophiopogonis 30g, Radix Scrophulariae 30g, Radix Adenophorae (Radix Glehniae) 20g, Herba Taraxaci 20g, Herba Ecliptae 15g, Fructus Ligustri Lucidi 12g, Fructus Mori 15g, Herba Dendrobii 12g, Rhizoma Polygonati Odorati 15g, Fructus Corni 15g, Radix Asparagi 15g, Flos Chrysanthemi 15g.
Embodiment 2
A kind of Chinese medicine composition of xerostomia, its raw material of Chinese medicine by following weight portion forms: Fructus Lycii 20g, Radix Rehmanniae 10g, Radix Rehmanniae Preparata 5g, Cortex Moutan 15g, Rhizoma Anemarrhenae 25g, Radix Ophiopogonis 40g, Radix Scrophulariae 20g, Radix Adenophorae (Radix Glehniae) 10g, Herba Taraxaci 30g, Herba Ecliptae 10g, Fructus Ligustri Lucidi 20g, Fructus Mori 25g, Herba Dendrobii 20g, Rhizoma Polygonati Odorati 5g, Fructus Corni 25g, Radix Asparagi 5g, Flos Chrysanthemi 20g.
Embodiment 3
A kind of Chinese medicine composition of xerostomia, its raw material of Chinese medicine by following weight portion forms: Fructus Lycii 25g, Radix Rehmanniae 5g, Radix Rehmanniae Preparata 20g, Cortex Moutan 20g, Rhizoma Anemarrhenae 15g, Radix Ophiopogonis 20g, Radix Scrophulariae 10g, Radix Adenophorae (Radix Glehniae) 30g, Herba Taraxaci 25g, Herba Ecliptae 5g, Fructus Ligustri Lucidi 10g, Fructus Mori 5g, Herba Dendrobii 25g, Rhizoma Polygonati Odorati 10g, Fructus Corni 20g, Radix Asparagi 25g, Flos Chrysanthemi 5g.
Embodiment 4
A kind of Chinese medicine composition of xerostomia, its raw material of Chinese medicine by following weight portion forms: Fructus Lycii 5g, Radix Rehmanniae 20g, Radix Rehmanniae Preparata 25g, Cortex Moutan 12g, Rhizoma Anemarrhenae 10g, Radix Ophiopogonis 10g, Radix Scrophulariae 25g, Radix Adenophorae (Radix Glehniae) 15g, Herba Taraxaci 10g, Herba Ecliptae 25g, Fructus Ligustri Lucidi 5g, Fructus Mori 10g, Herba Dendrobii 5g, Rhizoma Polygonati Odorati 25g, Fructus Corni 12g, Radix Asparagi 25g, Flos Chrysanthemi 12g.
Embodiment 5
A kind of Chinese medicine composition of xerostomia, its raw material of Chinese medicine by following weight portion forms: Fructus Lycii 10g, Radix Rehmanniae 25g, Radix Rehmanniae Preparata 10g, Cortex Moutan 5g, Rhizoma Anemarrhenae 30g, Radix Ophiopogonis 15g, Radix Scrophulariae 40g, Radix Adenophorae (Radix Glehniae) 25g, Herba Taraxaci 15g, Herba Ecliptae 12g, Fructus Ligustri Lucidi 25g, Fructus Mori 20g, Herba Dendrobii 15g, Rhizoma Polygonati Odorati 12g, Fructus Corni 5g, Radix Asparagi 10g, Flos Chrysanthemi 25g.
Chinese medicine composition in embodiment of the invention decocting method is routinely produced medicament, concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soaked 15~20 minutes, add again water and do not have approximately 10 centimetres of powder, once decoct, at a simmer the front intense fire that adopts decocts, and boils rear with slow fire boiling 20~30 minutes; Decoct for the second time, add water and do not have approximately 8 centimetres of powder, carry out secondary and decoct, the water rear decoction 15~20 minutes of boiling.Decoct approximately 400ml of extracting juice for twice, merge.
A kind of Chinese medicine composition for the treatment of xerostomia, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied to clinical treatment observation case 90 examples, male 56 examples wherein, women 34 examples, 35~70 years old its age.
Two, clinical manifestation: thirsty fidgety, dimly red tongue, constipation with dry stool, anorexia, whole body lassitude and weak.
Three, usage and dosage and points for attention: during clinical practice, take the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.This Chinese medicine composition potion on the one, twice extracting juice of decocting divides early, takes for late twice.Six days is a course for the treatment of.
Four, criterion of therapeutical effect:
Recovery from illness: symptom all disappears.
Effectively: symptom obviously alleviates.
Invalid: symptom such as front, without improving.
Five, therapeutic effect: in this clinical treatment observation case, take medicine 1~5 course for the treatment of 63 examples of fully recovering, effective 23 examples, invalid 4 examples.Have no toxic and side effects during the treatment.
Six, model case:
Case 1
Left certain, man, 60 years old.The main suit: more than xerostomia January, play drinking-water night 4~6 times, giddy is not hungry does not eat malaise, yellowish urine, red tongue.Through looking into: yellow and thin fur and few Tianjin, sublingual vein green grass or young crops is general.Take course for the treatment of of medicament of present composition preparation, xerostomia subtracts, and night, drinking-water reduced to 1~2 time; Continue to take medicine a course for the treatment of, the xerostomia symptom is eliminated, and recovery from illness is followed up a case by regular visits to and had no recurrence half a year.
Case 2
Jin, woman, 62 years old.Dispute is dry and astringent when medical, and very then tongue body rotates ineffectively, and more so need drink every night and gargle 4~5 times night, and general fatigue is unable.Take two courses for the treatment of of medicament of present composition preparation, conscious xerostomia symptom makes moderate progress, and the tongue body activity turns spirit, and drink was gargled 1~2 time and got final product night; Continue to take medicine two courses for the treatment of, xerostomia, weak symptom all disappear, recovery from illness.

Claims (2)

1. the Chinese medicine composition of an xerostomia, it is characterized in that: its raw material of Chinese medicine by following weight portion forms: 5~25 parts of Fructus Lyciis, 5~25 parts in the Radix Rehmanniae, 5~25 parts in Radix Rehmanniae Preparata, 5~20 parts of Cortex Moutans, 10~30 parts of the Rhizoma Anemarrhenaes, 10~40 parts of Radix Ophiopogonis, 10~40 parts of Radix Scrophulariaes, 10~30 parts of Radix Adenophorae (Radix Glehniae), 10~30 parts of Herba Taraxacis, 5~25 parts of Herba Ecliptaes, 5~25 parts of Fructus Ligustri Lucidi, 5~25 parts of Fructus Mori, 5~25 parts of Herba Dendrobiis, 5~25 parts of Rhizoma Polygonati Odorati, 5~25 parts of Fructus Corni, 5~25 parts of Radix Asparagi, 5~25 parts of Flos Chrysanthemis.
2. the Chinese medicine composition of a kind of xerostomia according to claim 1, it is characterized in that: its raw material of Chinese medicine by following weight portion forms: 15 parts of Fructus Lyciis, 15 parts in the Radix Rehmanniae, 15 parts in Radix Rehmanniae Preparata, 10 parts of Cortex Moutans, 20 parts of the Rhizoma Anemarrhenaes, 30 parts of Radix Ophiopogonis, 30 parts of Radix Scrophulariaes, 20 parts of Radix Adenophorae (Radix Glehniae), 20 parts of Herba Taraxacis, 15 parts of Herba Ecliptaes, 12 parts of Fructus Ligustri Lucidi, 15 parts of Fructus Mori, 12 parts of Herba Dendrobiis, 15 parts of Rhizoma Polygonati Odorati, 15 parts of Fructus Corni, 15 parts of Radix Asparagi, 15 parts of Flos Chrysanthemis.
CN2012103290454A 2012-09-07 2012-09-07 Traditional Chinese medicine composition for treating xerostomia Pending CN102872346A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103933392A (en) * 2014-04-10 2014-07-23 青岛市口腔医院 Pharmaceutical composition for treating xerostomia and application thereof
CN105250725A (en) * 2015-10-31 2016-01-20 王金环 Traditional Chinese medicine for treating xerostomia
CN105639592A (en) * 2016-02-25 2016-06-08 和县鸡笼山调味品有限责任公司 Wheat-containing soy sauce with kidney protecting and qi tonifying efficacy and preparation method of wheat-containing soy sauce
CN105661468A (en) * 2016-02-25 2016-06-15 和县鸡笼山调味品有限责任公司 Wheat sauce with effect of nourishing Yin and clearing fire and preparation method thereof
CN106491988A (en) * 2016-11-29 2017-03-15 湖南灼华生物科技有限公司 For improving Chinese medicine composition and the preparation method and applications of syndrome of yin deficiency of liver and kidney xerostomia dry pharynx

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103933392A (en) * 2014-04-10 2014-07-23 青岛市口腔医院 Pharmaceutical composition for treating xerostomia and application thereof
CN105250725A (en) * 2015-10-31 2016-01-20 王金环 Traditional Chinese medicine for treating xerostomia
CN105639592A (en) * 2016-02-25 2016-06-08 和县鸡笼山调味品有限责任公司 Wheat-containing soy sauce with kidney protecting and qi tonifying efficacy and preparation method of wheat-containing soy sauce
CN105661468A (en) * 2016-02-25 2016-06-15 和县鸡笼山调味品有限责任公司 Wheat sauce with effect of nourishing Yin and clearing fire and preparation method thereof
CN106491988A (en) * 2016-11-29 2017-03-15 湖南灼华生物科技有限公司 For improving Chinese medicine composition and the preparation method and applications of syndrome of yin deficiency of liver and kidney xerostomia dry pharynx

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Application publication date: 20130116