CN103800689A - Traditional Chinese medicine composition for treating diabetes mellitus - Google Patents

Traditional Chinese medicine composition for treating diabetes mellitus Download PDF

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Publication number
CN103800689A
CN103800689A CN201410057749.XA CN201410057749A CN103800689A CN 103800689 A CN103800689 A CN 103800689A CN 201410057749 A CN201410057749 A CN 201410057749A CN 103800689 A CN103800689 A CN 103800689A
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parts
radix
chinese medicine
medicine composition
rhizoma
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丁常燕
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Abstract

The invention relates to a traditional Chinese medicine composition for treating diabetes mellitus. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-30 parts of rehmannia root, 5-25 parts of dogwood, 10-30 parts of cortex lycii radicis, 5-25 parts of radix paeoniae alba, 5-20 parts of radix bupleuri, 5-25 parts of scutellaria baicalensis, 5-20 parts of capillary artemisia, 5-25 parts of cortex phellodendri, 5-20 parts of fructus aurantii, 5-25 parts of rhizoma alismatis, 5-20 parts of rhizoma corydalis, 5-25 parts of radix scrophulariae, 5-20 parts of poria, 5-25 parts of dendrobe, 10-30 parts of glossy privet fruits, 5-25 parts of eclipta alba, 5-20 parts of felwort, 5-20 parts of rhizoma atractylodis macrocephalae an 5-15 parts of liquorice. The traditional Chinese medicine composition disclosed by the invention has the effects of nourishing the liver and kidneys, purging fire for removing toxin, nourishing yin and clearing heat, cooling and nourishing blood, and is significant in curative effect on the diabetes mellitus, and reliable in action.

Description

A kind of Chinese medicine composition for the treatment of diabetes
Technical field
The present invention relates to a kind of pharmaceutical product of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of diabetes.
Background technology
Diabetes (diabetes) are to act on that body causes hypoinsulinism, insulin resistant etc. and a series of metabolism disturbance syndromes such as the sugar that causes, protein, fat, power and water Xie Zhi by various virulence factors such as inherited genetic factors, immunologic function disorder, infected by microbes and toxin thereof, free radical toxin, Nervous and Mental Factors, are classified as one of " three is large " killer of the mankind by the World Health Organization (WHO).Clinically take hyperglycemia as main feature, the performances such as polyuria, polydipsia, polyphagia can appear in model case, become thin, i.e. " three-many-one-little " symptom, diabetes (blood glucose) are once control and badly can cause complication, cause the exhaustion pathological changes at the positions such as kidney, eye, foot, and cannot cure.For many years, medical circle is devoted to the research to diabetes always, once this is that body immunity reduces because suffer from diabetes, easily infects by flu, pneumonia, caused various the catching of pulmonary tuberculosis, and is difficult for curing.
Along with increasing of taking in of the quickening of the raising of living standards of the people, rhythm of life and nutrition is even superfluous, the sickness rate of China's diabetes is constantly soaring, and number of patients has become a startling numeral.Diabetes and complication thereof just China people's healthy and life security in serious harm.The main medicines such as oral antidiabetic drug, euglycemic agent of applying are treated at present, most of Western medicine action pathway are single, very easily cause patient's hypoglycemia, islet beta cell function exhaustion and other are as the side effect such as edema, liver injury, the possibility that long-term taking needs dosage and has secondary to lose efficacy, Western medicine can not be controlled chronic complicating diseases effectively in addition.
The traditional Chinese medical science thinks, diabetes are mainly due to the plain body deficiency of YIN, eating and drinking without temperance, obesity, disorder of emotion, depression of liver-QI, diseases caused by exogenous pathogenic factor six climate exopathogens, due to the evil infringement of poison.
According to theory of Chinese medical science, for the pathogeny of diabetes, adopt the method for the treatment of of nourishing the liver and kidney, eliminating fire and detoxication, nourishing YIN and clearing away heat, carry out dialectical prescription compatibility, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Can only relief of symptoms and can not effect a permanent cure and exist the deficiency of side effect in order to overcome prior art integrative therapy diabetes, the invention provides a kind of prepare easy, cost is low, the Chinese medicine composition of evident in efficacy, the treatment diabetes that have no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of diabetes, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Rehmanniae 10-30 part, Fructus Corni 5-25 part, Cortex Lycii 10-30 part, Radix Paeoniae Alba 5-25 part, Radix Bupleuri 5-20 part, Radix Scutellariae 5-25 part, Herba Artemisiae Scopariae 5-20 part, Cortex Phellodendri 5-25 part, Fructus Aurantii 5-20 part, Rhizoma Alismatis 5-25 part, Rhizoma Corydalis 5-20 part, Radix Scrophulariae 5-25 part, Poria 5-20 part, Herba Dendrobii 5-25 part, Fructus Ligustri Lucidi 10-30 part, Herba Ecliptae 5-25 part, Radix Gentianae 5-20 part, Rhizoma Atractylodis Macrocephalae 5-20 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of diabetes, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 20 parts, the Radix Rehmanniae, 15 parts of Fructus Corni, 20 parts of Cortex Lycii, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Bupleuri, 15 parts of Radix Scutellariaes, 10 parts of Herba Artemisiae Scopariaes, 15 parts of Cortex Phellodendris, 10 parts of Fructus Aurantiis, 15 parts of Rhizoma Alismatis, 10 parts of Rhizoma Corydalis, 15 parts of Radix Scrophulariaes, 10 parts of Poria, 15 parts of Herba Dendrobiis, 20 parts of Fructus Ligustri Lucidi, 15 parts of Herba Ecliptaes, 10 parts of Radix Gentianaes, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: the Radix Rehmanniae has effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, pain relieving regulating menstruation; Fructus Corni has effect of liver and kidney tonifying, essence astringing and desertion stemming; Cortex Lycii has removing heat from blood effect except steaming, lung heat clearing pathogenic fire reducing; The Radix Paeoniae Alba has effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Radix Bupleuri have evacuate bring down a fever, effect of yang invigorating soothing liver-QI; Radix Scutellariae has effect of heat clearing and damp drying, eliminating fire and detoxication, arresting bleeding and miscarriage prevention; Herba Artemisiae Scopariae has effect of clearing away heat-damp and promoting diuresis, hepatic cholagogic; Cortex Phellodendri has heat clearing and damp drying, pathogenic fire purging except steaming, effect of detoxification sore treatment; Fructus Aurantii has effect of regulating the flow of QI to ease the stomach, the stagnant relieving distension of row; Rhizoma Alismatis has promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil; Rhizoma Corydalis has effect of promoting blood circulation to remove blood stasis, promoting the circulation of QI pain relieving; Radix Scrophulariae has effect of removing heat from blood YIN nourishing, eliminating fire and detoxication; Poria has benefiting vital QI for tranquillizing, invigorating the spleen and regulating the stomach, dispels effect damp and hot, row water stopping leak; Herba Dendrobii has effect of reinforcing stomach reg fluid, nourishing YIN and clearing away heat; Fructus Ligustri Lucidi has effect that nourishing the liver and kidney, tonifying YIN nourish blood; Herba Ecliptae has effect of liver-nourishing kidney-boosting, cooling blood for hemostasis; Radix Gentianae has effect of heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire; The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, the antiabortive effect of hidroschesis; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component is through dialectical compatibility, helps using mutual assistant, plays altogether effect that nourishing the liver and kidney, eliminating fire and detoxication, nourishing YIN and clearing away heat, removing heat from blood nourish blood, and the treatment of diabetes is reached to treating both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, does not occur toxic and side effects, and effective percentage reaches 89%, cure rate 41%.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described.
embodiment 1
Treat a Chinese medicine composition for diabetes, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 20g, Fructus Corni 15g, Cortex Lycii 20g, Radix Paeoniae Alba 15g, Radix Bupleuri 10g, Radix Scutellariae 15g, Herba Artemisiae Scopariae 10g, Cortex Phellodendri 15g, Fructus Aurantii 10g, Rhizoma Alismatis 15g, Rhizoma Corydalis 10g, Radix Scrophulariae 15g, Poria 10g, Herba Dendrobii 15g, Fructus Ligustri Lucidi 20g, Herba Ecliptae 15g, Radix Gentianae 10g, Rhizoma Atractylodis Macrocephalae 10g, Radix Glycyrrhizae 10g.
embodiment 2
Treat a Chinese medicine composition for diabetes, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 15g, Fructus Corni 25g, Cortex Lycii 10g, Radix Paeoniae Alba 20g, Radix Bupleuri 5g, Radix Scutellariae 25g, Herba Artemisiae Scopariae 12g, Cortex Phellodendri 20g, Fructus Aurantii 5g, Rhizoma Alismatis 20g, Rhizoma Corydalis 12g, Radix Scrophulariae 25g, Poria 5g, Herba Dendrobii 20g, Fructus Ligustri Lucidi 10g, Herba Ecliptae 25g, Radix Gentianae 5g, Rhizoma Atractylodis Macrocephalae 20g, Radix Glycyrrhizae 12g.
embodiment 3
Treat a Chinese medicine composition for diabetes, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 25g, Fructus Corni 5g, Cortex Lycii 30g, Radix Paeoniae Alba 10g, Radix Bupleuri 15g, Radix Scutellariae 20g, Herba Artemisiae Scopariae 12g, Cortex Phellodendri 25g, Fructus Aurantii 12g, Rhizoma Alismatis 10g, Rhizoma Corydalis 20g, Radix Scrophulariae 5g, Poria 15g, Herba Dendrobii 10g, Fructus Ligustri Lucidi 25g, Herba Ecliptae 10g, Radix Gentianae 15g, Rhizoma Atractylodis Macrocephalae 12g, Radix Glycyrrhizae 5g.
embodiment 4
Treat a Chinese medicine composition for diabetes, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 10g, Fructus Corni 20g, Cortex Lycii 15g, Radix Paeoniae Alba 25g, Radix Bupleuri 12g, Radix Scutellariae 5g, Herba Artemisiae Scopariae 15g, Cortex Phellodendri 10g, Fructus Aurantii 20g, Rhizoma Alismatis 5g, Rhizoma Corydalis 15g, Radix Scrophulariae 10g, Poria 20g, Herba Dendrobii 5g, Fructus Ligustri Lucidi 15g, Herba Ecliptae 20g, Radix Gentianae 12g, Rhizoma Atractylodis Macrocephalae 5g, Radix Glycyrrhizae 8g.
embodiment 5
Treat a Chinese medicine composition for diabetes, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 30g, Fructus Corni 10g, Cortex Lycii 25g, Radix Paeoniae Alba 5g, Radix Bupleuri 20g, Radix Scutellariae 10g, Herba Artemisiae Scopariae 20g, Cortex Phellodendri 5g, Fructus Aurantii 15g, Rhizoma Alismatis 25g, Rhizoma Corydalis 5g, Radix Scrophulariae 20g, Poria 12g, Herba Dendrobii 25g, Fructus Ligustri Lucidi 30g, Herba Ecliptae 5g, Radix Gentianae 20g, Rhizoma Atractylodis Macrocephalae 15g, Radix Glycyrrhizae 15g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and cover powder, soak 15~20 minutes, then add water and do not have approximately 6 centimetres of powder, decoct for the first time, adopt intense fire to decoct before at a simmer, after boiling with slow fire boiling 20~30 minutes; Decoct for the second time, add water and do not have approximately 4 centimetres of powder, after water boils, decoct 15~20 minutes.Decoct extracting juice twice, merge.
The present invention, with the given a kind of Chinese medicine composition for the treatment of diabetes of embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 100 examples, male 48 examples, female's 52 examples, 45~75 years old age.
Two, clinical manifestation: all patients all have blood sugar content on an empty stomach high and have xerostomia in various degree, the symptom such as thirsty, fatigue is weak, lower limb are aching and limp, light red, the thin fur of lumbago, night urine increased frequency, palm of the hand dysphoria with smothery sensation, body of the tongue, thready and rapid pulse.
Three, diagnosis basis:
(1) thirsty polydipsia, polyorexia, urinary micturition, emaciated physique;
(2) from the beginning of can " more than three " symptom not showing.Sick Chang Bingfa is dizzy for a long time, pulmonary tuberculosis, the thoracic obstruction, apoplexy, nyctalopia, furuncle etc.The visible excessive thirst of severe patient, headache, vomiting, stomachache, short of breath, the de-crisis even stupor is fainted;
(3) look on an empty stomach, 2 hours after the meal glucoses in urine and blood glucose, specific gravity of urine, glucose tolerance test.The ketoboidies that has urine examined if desired, blood urea nitrogen, creatinine, CO2 combining power, CO2 CP and blood potassium, sodium, calcium, chloride etc.
Three, usage and dosage: when clinical practice, potion on the one, the about 400ml of twice extracting juice of decocting, point morning, late twice empty stomach decoction being taken warmly.It within five days, is a course for the treatment of.
Four, criterion of therapeutical effect: the diabetes curative effect standard of formulating with reference to " new Chinese medicine guideline of clinical investigations ":
(1) recovery from illness: sings and symptoms improves completely, and living and diet is normal, in high spirits; Lab testing is repeatedly normal;
(2) effective: sings and symptoms significantly improves, living and diet is normal, and spirit is good greatly; Relevant lab testing has clear improvement;
(3) effective: sings and symptoms makes moderate progress, random thoughts are uncomfortable, but can accept; Relevant lab testing is improved;
(4) invalid; Sings and symptoms is all not improved, and symptom is as front; Lab testing is unchanged.
Five, therapeutic effect: in this clinical observation case, take medicine 2-10 the course for the treatment of, recovery from illness 41 examples, follow up a case by regular visits to and have no recurrence; Effective 27 examples, effective 21 examples, invalid 11 examples.During treatment, there is not toxic and side effects.
Six, model case:
Case 1: grandson, female, 48 years old.Patient's readme: feel in the recent period weak, breathe hard, spontaneous perspiration, moving increase the weight of dry mouth and tougue, polydipsia polyuria, constipation, soreness of the waist and knees.Examine and see: red tongue is dark, indentations at the margin of the tongue, the few Tianjin of white and thin fur, thready and weak pulse.Fasting glucose 9.4mmol/L.Be diagnosed as: diabetes 2 types.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom alleviates; Continue to take 5 courses for the treatment of and consolidate, fasting glucose is less than 7.After half a year, visit, blood glucose value is normal.
Case 2: in certain, man, 53 years old.Patient's polyorexia, emaciated physique, constipation with dry stool.Examine and see: yellow fur is dry, slippery and rapid pulse.Fasting glucose 9.2mmol/L.Be diagnosed as: diabetes.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom obviously alleviates; Continue to take 4 courses for the treatment of, all symptoms disappear completely, and blood glucose value is normal.Follow up a case by regular visits to half a year without recurrence.
Case 3: Wang, man, 61 years old.Patient's disease is seen: xerostomia, fatigue is weak, lower limb are aching and limp, light red, the thin fur of lumbago, night urine increased frequency, palm of the hand dysphoria with smothery sensation, body of the tongue, thready and rapid pulse.Take 5 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, xerostomia alleviates, weak remission; Continue to take 4 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, all symptoms disappear completely, cure.

Claims (2)

1. a Chinese medicine composition for the treatment of diabetes, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Rehmanniae 10-30 part, Fructus Corni 5-25 part, Cortex Lycii 10-30 part, Radix Paeoniae Alba 5-25 part, Radix Bupleuri 5-20 part, Radix Scutellariae 5-25 part, Herba Artemisiae Scopariae 5-20 part, Cortex Phellodendri 5-25 part, Fructus Aurantii 5-20 part, Rhizoma Alismatis 5-25 part, Rhizoma Corydalis 5-20 part, Radix Scrophulariae 5-25 part, Poria 5-20 part, Herba Dendrobii 5-25 part, Fructus Ligustri Lucidi 10-30 part, Herba Ecliptae 5-25 part, Radix Gentianae 5-20 part, Rhizoma Atractylodis Macrocephalae 5-20 part, Radix Glycyrrhizae 5-15 part.
2. a kind of Chinese medicine composition for the treatment of diabetes according to claim 1, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 20 parts, the Radix Rehmanniae, 15 parts of Fructus Corni, 20 parts of Cortex Lycii, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Bupleuri, 15 parts of Radix Scutellariaes, 10 parts of Herba Artemisiae Scopariaes, 15 parts of Cortex Phellodendris, 10 parts of Fructus Aurantiis, 15 parts of Rhizoma Alismatis, 10 parts of Rhizoma Corydalis, 15 parts of Radix Scrophulariaes, 10 parts of Poria, 15 parts of Herba Dendrobiis, 20 parts of Fructus Ligustri Lucidi, 15 parts of Herba Ecliptaes, 10 parts of Radix Gentianaes, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts, Radix Glycyrrhizae.
CN201410057749.XA 2014-02-20 2014-02-20 Traditional Chinese medicine composition for treating diabetes mellitus Pending CN103800689A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105497559A (en) * 2015-12-17 2016-04-20 刘爱华 Pharmaceutical composition with blood glucose lowering function
CN108066707A (en) * 2018-01-09 2018-05-25 宁夏医科大学 Reduce Chinese medicine composition, its preparation method and the application of blood glucose
CN111346196A (en) * 2019-04-17 2020-06-30 杨德威 Traditional Chinese medicine for treating diabetes and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1565583A (en) * 2003-07-04 2005-01-19 岐黄药业科技投资有限责任公司 Chinese drugs compositions for treating diabetes and its complications
CN1634174A (en) * 2003-12-29 2005-07-06 林明兴 Chinese traditional medicine for treating diabetes
CN101195001A (en) * 2007-12-03 2008-06-11 门连社 Chinese medicine prescription for treating hypertension, hypercholesterolemia and hyperglycemia

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1565583A (en) * 2003-07-04 2005-01-19 岐黄药业科技投资有限责任公司 Chinese drugs compositions for treating diabetes and its complications
CN1634174A (en) * 2003-12-29 2005-07-06 林明兴 Chinese traditional medicine for treating diabetes
CN101195001A (en) * 2007-12-03 2008-06-11 门连社 Chinese medicine prescription for treating hypertension, hypercholesterolemia and hyperglycemia

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105497559A (en) * 2015-12-17 2016-04-20 刘爱华 Pharmaceutical composition with blood glucose lowering function
CN108066707A (en) * 2018-01-09 2018-05-25 宁夏医科大学 Reduce Chinese medicine composition, its preparation method and the application of blood glucose
CN111346196A (en) * 2019-04-17 2020-06-30 杨德威 Traditional Chinese medicine for treating diabetes and preparation method thereof

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Application publication date: 20140521