CN111346196A - Traditional Chinese medicine for treating diabetes and preparation method thereof - Google Patents

Traditional Chinese medicine for treating diabetes and preparation method thereof Download PDF

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CN111346196A
CN111346196A CN201910306121.1A CN201910306121A CN111346196A CN 111346196 A CN111346196 A CN 111346196A CN 201910306121 A CN201910306121 A CN 201910306121A CN 111346196 A CN111346196 A CN 111346196A
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treating diabetes
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杨德威
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638—Ligustrum, e.g. Chinese privet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
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Abstract

The invention provides a traditional Chinese medicine for treating diabetes, which comprises the following raw materials in parts by weight: 30 parts of eclipta alba, 30 parts of glossy privet fruit, 15 parts of semen cuscutae, 15 parts of radix bupleuri, 10 parts of dried orange peel, 10 parts of green tangerine peel, 5 parts of fructus aurantii immaturus, 15 parts of rhizoma atractylodis macrocephalae, 10 parts of radix paeoniae alba, 10 parts of cortex phellodendri, 15 parts of radix curcumae, 15 parts of radix rehmanniae preparata, 25 parts of turtle shell and 25 parts of golden larch plate. Compared with the conventional method for treating diabetes, the traditional Chinese medicine is adopted for treatment, has no toxic or side effect, does not damage the human body, is convenient to treat, and can obviously reduce the phenomenon of systemic complications caused by diabetes after being taken for a period of time.

Description

Traditional Chinese medicine for treating diabetes and preparation method thereof
Technical Field
The invention relates to the technical field of diabetes treatment formulas, in particular to a traditional Chinese medicine for treating diabetes and a preparation method thereof.
Background
Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia, which is caused by insulin secretion deficiency or impaired biological action, or both, and has clinical manifestations: (1) polydipsia, polyuria, polyphagia and emaciation, typical 'more than three and one less' symptoms appear when severe hyperglycemia occurs, and the 'more than three and one less' symptoms are more obvious when ketosis or ketoacidosis occurs, which is mostly seen in type 1 diabetes; (2) fatigue, weakness and obesity are commonly seen in type 2 diabetes; obesity usually occurs before type 2 diabetes, and if the diabetes cannot be diagnosed in time, the weight of the patient gradually decreases. Hyperglycemia occurring in the long term of diabetes results in chronic damage to, and dysfunction of, various tissues, particularly the eyes, kidneys, heart, blood vessels, nerves. Among them, type 1 diabetes: the disease is mild in age, mostly less than 30 years old, sudden onset, obvious symptoms of polydipsia, diuresis, polyphagia and emaciation, high blood sugar level, the first symptom of ketoacidosis of many patients, low levels of serum insulin and C-peptide, positive ICA, IAA or GAD antibodies, and ineffective by taking oral medicines alone, and the patients need to be treated by insulin. Type 2 diabetes: the traditional Chinese medicine composition is common to middle-aged and elderly people, obesity patients have high morbidity, and are often accompanied with diseases such as hypertension, dyslipidemia, arteriosclerosis and the like, the diseases are insidious, no symptom exists in the early stage, or only mild hypodynamia, thirst and unobvious blood sugar increase can be diagnosed by performing a sugar tolerance test, and the serum insulin level is normal or increased in the early stage and is low in the later stage. Insulin is very inconvenient for the treatment of diabetes, cannot be cured radically and has high treatment cost.
Disclosure of Invention
Aiming at the defects, the invention aims to provide the traditional Chinese medicine for treating diabetes and the preparation method thereof, solves the problems in the background art, and meets the actual use requirement.
The invention is realized by the following technical scheme:
a traditional Chinese medicine for treating diabetes comprises the following raw materials in parts by weight: 30 parts of eclipta alba, 30 parts of glossy privet fruit, 15 parts of semen cuscutae, 15 parts of radix bupleuri, 10 parts of dried orange peel, 10 parts of green tangerine peel, 5 parts of fructus aurantii immaturus, 15 parts of rhizoma atractylodis macrocephalae, 10 parts of radix paeoniae alba, 10 parts of cortex phellodendri, 15 parts of radix curcumae, 15 parts of radix rehmanniae preparata, 25 parts of turtle shell and 25 parts of golden larch plate.
As an improvement of the technical scheme, the eclipta alba, the glossy privet fruit, the dodder seed, the Chinese thorowax root, the tangerine peel, the green tangerine peel, the fructus aurantii immaturus, the bighead atractylodes rhizome, the white paeony root, the golden cypress, the turmeric root-tuber, the prepared rhizome of rehmannia, the turtle shell and the golden larkshood tortoise plastron in parts by weight can be prepared in different weight proportions on the premise that the original medicine formula is not changed according to simple symptoms, complications, combined diseases and the like of the body of.
Specifically, the preparation method of the traditional Chinese medicine for treating diabetes comprises the following steps:
s1: taking traditional Chinese medicine raw materials according to the weight parts, removing mildewed traditional Chinese medicine materials, cleaning the traditional Chinese medicine materials, and naturally drying the traditional Chinese medicine materials to ensure that the water content is 5-8%;
s2: cleaning the traditional Chinese medicinal materials, respectively putting the traditional Chinese medicinal materials into a pulverizer for pulverizing, sieving by a 50-100 mesh sieve after pulverizing, respectively putting the pulverized traditional Chinese medicinal materials into different sealed stainless steel cans with equal weight, and adding the traditional Chinese medicinal materials into the stainless steel cans according to the relationship of 30 parts of eclipta alba, 30 parts of glossy privet fruit, 15 parts of dodder, 15 parts of radix bupleuri, 10 parts of dried orange peel, 10 parts of green tangerine peel, 5 parts of fructus Aurantii, 15 parts of bighead atractylodes rhizome, 10 parts of white peony root, 10 parts of golden cypress, 15 parts of radix curcumae, 15 parts of prepared rehmannia root, 25 parts of turtle shell and 25 parts of nux vomica;
s3: adding the traditional Chinese medicinal materials in the stainless steel tank body in the S2 into a mixer together, and mixing for 10 minutes;
s4: filling the mixed traditional Chinese medicinal materials into clean packaging bags by a filling machine in equal weight, and packaging and sealing by a vacuum packaging machine.
As an improvement of the technical scheme, the stainless steel tank body is cleaned after being used, is irradiated for 10-20min by ultraviolet rays, and is immediately sealed by a cover after irradiation, so that dust and bacteria are prevented from entering.
As an improvement of the technical scheme, after the packaging in S4 is finished, whether the packaging bag is well packaged or not is checked, and the packaging tape which is not well packaged is repackaged.
The invention has the beneficial effects that: compared with the conventional method for treating diabetes, the traditional Chinese medicine is adopted for treatment, has no toxic or side effect, does not damage the human body, is convenient to treat, and can obviously reduce the phenomenon of systemic complications caused by diabetes after being taken for a period of time.
Detailed Description
Example (b):
the traditional Chinese medicine for treating diabetes comprises the following raw materials in parts by weight: 30 parts of eclipta alba, 30 parts of glossy privet fruit, 15 parts of semen cuscutae, 15 parts of radix bupleuri, 10 parts of dried orange peel, 10 parts of green tangerine peel, 5 parts of fructus aurantii immaturus, 15 parts of rhizoma atractylodis macrocephalae, 10 parts of radix paeoniae alba, 10 parts of cortex phellodendri, 15 parts of radix curcumae, 15 parts of radix rehmanniae preparata, 25 parts of turtle shell and 25 parts of golden larch plate; wherein, the eclipta alba, the glossy privet fruit, the south dodder seed, the Chinese thorowax root, the tangerine peel, the green tangerine peel, the fructus aurantii immaturus, the largehead atractylodes rhizome, the white paeony root, the amur corktree bark, the turmeric root-tuber, the prepared rhizome of rehmannia, the turtle shell and the golden larkshood tortoise plastron in parts by weight can be prepared in different weight proportions on the premise that the original prescription is not changed according to simple symptoms, complications, combined diseases and the like of the.
The preparation method of the traditional Chinese medicine for treating diabetes comprises the following steps:
s1: taking traditional Chinese medicine raw materials according to the weight parts, removing mildewed traditional Chinese medicine materials, cleaning the traditional Chinese medicine materials, and naturally drying the traditional Chinese medicine materials to ensure that the water content is 5-8%;
s2: cleaning the traditional Chinese medicinal materials, respectively putting the traditional Chinese medicinal materials into a pulverizer for pulverizing, sieving by a 50-100 mesh sieve after pulverizing, respectively putting the pulverized traditional Chinese medicinal materials into different sealed stainless steel cans with equal weight, and adding the traditional Chinese medicinal materials into the stainless steel cans according to the relationship of 30 parts of eclipta alba, 30 parts of glossy privet fruit, 15 parts of dodder, 15 parts of radix bupleuri, 10 parts of dried orange peel, 10 parts of green tangerine peel, 5 parts of fructus Aurantii, 15 parts of bighead atractylodes rhizome, 10 parts of white peony root, 10 parts of golden cypress, 15 parts of radix curcumae, 15 parts of prepared rehmannia root, 25 parts of turtle shell and 25 parts of nux vomica;
s3: adding the traditional Chinese medicinal materials in the stainless steel tank body in the S2 into a mixer together, and mixing for 10 minutes;
s4: filling the mixed traditional Chinese medicines into clean packaging bags by using a filling machine in equal weight, and packaging and sealing by using a vacuum packaging machine (after the packaging in S4 is finished, checking whether the packaging bags are well packaged, and repackaging the unpackaged packaging tapes).
Specifically, the stainless steel tank body is cleaned after use, irradiated by ultraviolet rays for 10-20min, and immediately sealed by a cover after irradiation, so that dust and bacteria are prevented from entering.
Clinical cases: zhangiao, 43 years old, has diabetes, and has symptoms of drinking polydipsia, myocardial infarction, visual deterioration, hearing loss, eating hunger, no injection of insulin fasting blood glucose, 21 postprandial blood glucose 31, 16 units of insulin required to be injected before meals every day, 28 days of administration of the medicine, 2 to 3 units of insulin required to be injected before meals every day, and improvement of symptoms under normal meal amount, wherein only 1 unit of insulin is required to be injected every day after 9 months of continuous administration. The taking method comprises the following steps: soaking in water for 15-30 min, adding 3 times of water, decocting with strong fire in casserole or enamel pot until the water is boiling, decocting with slow fire for 30 min, filtering to remove residue, and collecting decoction.
The preparation method of the traditional Chinese medicine for treating diabetes not only has the effect of treating diabetes, but also has other effects of the traditional Chinese medicine because the traditional Chinese medicine is prepared from pure traditional Chinese medicines, such as: eclipta alba: herba Ecliptae has effects of nourishing liver and kidney, blackening beard and consolidating teeth, cooling blood and stopping bleeding, and can be used for treating liver and kidney deficiency, giddiness tinnitus, blurred vision, soreness of waist and knees, whitish tooth shaking, overstrain with turbid urine, hemoptysis, hematemesis, epistaxis, hematuria, bloody dysentery, metrorrhagia, and traumatic hemorrhage. Glossy privet fruit: nourishing liver and kidney, improving eyesight and blackening hair. They belong to the category of deficiency-tonifying herbs. Chinese dodder seed: has the functions of nourishing liver and kidney, benefiting essence and marrow, improving eyesight, treating soreness and pain of waist and knees, spermatorrhea, diabetes, dribbling urine and dim eyesight, is a common medicine for tonifying kidney, reducing urination and stopping spermatorrhea, and is used for treating soreness and pain of waist and knees, impotence and spermatorrhea caused by deficiency of liver and kidney. It is soft and moist in property, and can tonify liver and kidney without dryness. Bupleurum root: clearing away heat and toxic materials, promoting blood circulation, promoting urination, and can be used for treating tonsillitis, pharyngolaryngitis, urinary tract infection, pelvic inflammatory disease, appendicitis, hepatitis, bacillary dysentery, venomous snake bite, tumor, enhancing immunity, and inhibiting growth of tumor cells.
White peony root: has the functions of softening liver, relieving pain, hypochondriac pain, tranquilizing, resisting bacteria, nourishing blood, astringing yin, arresting sweating, etc. Glabrous greenbrier rhizome: has the effects of removing dampness and detoxifying, and has obvious effect on treating sinew and bone contracture pain.
The traditional Chinese medicine for treating diabetes prepared by the embodiment of the invention is used for randomly treating patients with several symptoms, and the obtained data is as follows:
Figure DEST_PATH_IMAGE002
in addition, the formula and the preparation process adopted by the invention lead the essence component of the traditional Chinese medicine composition to have better treatment effect on the diabetic patients; in addition, the traditional Chinese medicine composition has very good permeability, and the appetite is enhanced, so the traditional Chinese medicine composition has a certain treatment effect on anorexia patients.

Claims (5)

1. A traditional Chinese medicine for treating diabetes is characterized in that: the raw materials are as follows by weight: 30 parts of eclipta alba, 30 parts of glossy privet fruit, 15 parts of semen cuscutae, 15 parts of radix bupleuri, 10 parts of dried orange peel, 10 parts of green tangerine peel, 5 parts of fructus aurantii immaturus, 15 parts of rhizoma atractylodis macrocephalae, 10 parts of radix paeoniae alba, 10 parts of cortex phellodendri, 15 parts of radix curcumae, 15 parts of radix rehmanniae preparata, 25 parts of turtle shell and 25 parts of golden larch plate.
2. The traditional Chinese medicine for treating diabetes according to claim 1, characterized in that: the eclipta alba, the glossy privet fruit, the dodder, the radix bupleuri, the dried orange peel, the green tangerine peel, the fructus aurantii immaturus, the bighead atractylodes rhizome, the white paeony root, the golden cypress, the radix curcumae, the prepared rhizome of rehmannia, the turtle shell and the golden larch plate are combined in different weight proportions on the premise that the original prescription is not changed according to simple symptoms, complications, combined diseases and the like of the body of a diabetic patient.
3. The preparation method of the traditional Chinese medicine for treating diabetes according to claim 1, characterized in that: the method comprises the following steps: s1: taking traditional Chinese medicine raw materials according to the weight parts, removing mildewed traditional Chinese medicine materials, cleaning the traditional Chinese medicine materials, and naturally drying the traditional Chinese medicine materials to ensure that the water content is 5-8%; s2: cleaning the traditional Chinese medicinal materials, respectively putting the traditional Chinese medicinal materials into a pulverizer for pulverizing, sieving by a 50-100 mesh sieve after pulverizing, respectively putting the pulverized traditional Chinese medicinal materials into different sealed stainless steel cans with equal weight, and adding the traditional Chinese medicinal materials into the stainless steel cans according to the relationship of 30 parts of eclipta alba, 30 parts of glossy privet fruit, 15 parts of dodder, 15 parts of radix bupleuri, 10 parts of dried orange peel, 10 parts of green tangerine peel, 5 parts of fructus Aurantii, 15 parts of bighead atractylodes rhizome, 10 parts of white peony root, 10 parts of golden cypress, 15 parts of radix curcumae, 15 parts of prepared rehmannia root, 25 parts of turtle shell and 25 parts of nux vomica; s3: adding the traditional Chinese medicinal materials in the stainless steel tank body in the S2 into a mixer together, and mixing for 10 minutes; s4: filling the mixed traditional Chinese medicinal materials into clean packaging bags by a filling machine in equal weight, and packaging and sealing by a vacuum packaging machine.
4. The preparation method of the traditional Chinese medicine for treating diabetes according to claim 3, characterized in that: the stainless steel tank body is cleaned after use, irradiated by ultraviolet rays for 10-20min and immediately sealed by a cover after irradiation, so that dust and bacteria are prevented from entering.
5. The preparation method of the traditional Chinese medicine for treating diabetes according to claim 3, characterized in that: and (S4) checking whether the packaging bag is completely packaged after the packaging is finished, and repackaging the unpackaged packaging tape.
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