CN105998448A

CN105998448A - Method for preparing mulberry oral solution for improving immunity and oral solution prepared by same

Info

Publication number: CN105998448A
Application number: CN201610620898.1A
Authority: CN
Inventors: 马佳
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-08-02
Filing date: 2016-08-02
Publication date: 2016-10-12

Abstract

The invention discloses a method for preparing a mulberry oral solution for improving immunity. The method comprises the following steps: a, extracting mulberry to serve as a component 1; b, putting other medicinal raw materials into ethanol, heating, refluxing and extracting twice to service as a component 2; c, mixing the component 1 and the component 2, concentrating, and mixing with honey or dextrin, disinfecting and sterilizing to obtain the oral solution. In the step a, the mulberry fruits are collected when ripe in April to June each year, cleaning, removing impurities, drying in the sun or slightly steaming and drying in the sun. According to the preparation method, mulberry serving as a main material is mixed with traditional Chinese medicinal materials which have the effects of nourishing liver and kidneys, and promoting blood circulation and supplementing marrow and are mild in properties and flavors, the taste can be remarkably improved, and great improvement is achieved for bitter flavor, poor taste and inconvenient use of traditional Chinese medicines. The medicinal materials are mixed to achieve the effects of tonifying lung, nourishing kidneys, astringing lung-qi, relieving cough and asthma and improving brains, so that intelligence can be improved, body can be strengthened, and a certain senescence resistance can be achieved.

Description

Improve Fructus Mori oral liquor and the oral liquid thereof of immunity

Technical field

The present invention relates to, containing the medical health product deriving from plant, animal or raw mineral materials, improve particularly to one Fructus Mori oral liquid of immunity and preparation method thereof.

Background technology

Over millions of years, the mankind are at one environment being not only suitable for existence but also being fraught with risks of life, and the mankind are able to survival, also obtain Obtained outstanding immunity.Immunity is the product of biological evolution process thus.

Immunity is the defense mechanism of human body self, is that any foreign body of human bioequivalence and the external intrusion of elimination is (viral, thin Bacterium etc.)；Process aging, damage, dead, the own cells of degeneration and identification and process vivo mutations cell and virus infects carefully The ability of born of the same parents.Immunology Today is thought, immunity is human bioequivalence and the physiological reaction getting rid of " dissident ".This is performed in human body Function is immune system.

Immunity can be divided into by the difference of its acquisition pattern: 1.Innate immunity, is that people is once being born.Such as swine fever Swinery is propagated quickly, but has no chance with the mankind.This is because the mankind innately would not obtain this disease；2.Acquired immunity, be People obtains after being born in life process naturally, or passively obtains by the method for human assistance.

The health of hypoimmunity is prone to infected or cancer stricken；Immunity is extraordinary also can produce insalubrious knot Really, as caused anaphylaxis, autoimmune disease etc..

A variety of causes makes immune system can not normally play protective effect, in the case, easily cause antibacterial, virus, Funguses etc. infect, and therefore hypoimmunity the most directly shows is exactly liable to illness.Because of the most ill, increase the weight of disappearing of body Consumption, thus typically have a delicate constitution, reductions of malnutrition, lethargy, fatigue and weak, appetite, the performance such as sleep disorder, give birth to Sick, having an injection to take medicine has become homely food.The most sick will being lot more time to is recovered, and usually recurrent exerbation.Grow this Health and intelligent development can be caused in the past bad, the most easily induced major disease.

Underlying causes be hypoimmunity or immunity unsound.When immune function of human body is lacked of proper care, or immune system is not When perfecting, following point will recurrent exerbation:--flu recurrent exerbation, tonsillitis recurrent exerbation, asthma recurrent exerbation, a gas Pipe inflammation recurrent exerbation, pneumonia recurrent exerbation, diarrhoea recurrent exerbation ... so necessarily can't neglect.

Immunity refers to that body resists external invasion and attack, safeguards the ability of homoiostasis.Air is filled with various The microorganism of various kinds: antibacterial, virus, mycoplasma, chlamydia, fungus etc..In the case of body immunity is low, they are all The pathogen of sense mornig shift can be become.Although human body can produce corresponding antibody to different pathogen, to resist subinfection again, But antibody has specificity and time-bounded, such as streptococcus antibody can only protect in short period of time body not by streptococcic again Secondary infringement, also can not resist the infection of other viruses.The people of hypoimmunity cannot resist the invasion and attack of cold virus at all, this It is only the true cause that he frequently catches a cold.

Investigating according to bioscience man, the number of times of biological cell division was directly proportional to the life-span, and such as, the cell of dolphin divides Splitting number of times is 80 times, and its average life is then up to 150 years old.And the reason of the human senility composition that human body life is most basic just Unit-cell occurs in that decay.Along with the increase at age, the division of cell regeneration is increasingly slower, and the aged cells of accumulation makes device The function of official constantly declines, and aging even pathological changes occurs, and people is the oldest and the most feeble.

Fructus Mori are the mature fruit of Moraceae deciduous tree mulberry, and Fructus Mori are again sorosis, Mulberry Fructus Jujubae, and peasant likes the fresh of its maturation Fruit is edible, and taste sweet juice is many, is one of fruit of often eating of people.Chinese medicine thinks Fructus Mori liver and kidney tonifying, nourishing YIN and benefiting blood, endogenous wind stopping, tool Cure mainly palpitation and insomnia, have a dizzy spell, tinnitus, constipation night sweat, scrofula, the disease such as articular instability.Fructus Mori have and improve skin and (include Scalp) blood supply, nutrition skin, make skin delicate and black hair etc. acts on, and can improve immunity.Fructus Mori are that middle-aged and elderly people is good for Body U.S. face, the good fruit of defying age and good medicine.Often food Fructus Mori can be with improving eyesight, the symptom that relieving eye strain is dry and astringent.Fructus Mori have exempts from Epidemic disease facilitation.Fructus Mori have effect of gain to spleen, and hemolytic reaction is had potentiation, can prevent human body artery hardening, bone Bone arthrosclerosis, enhances metabolism.It can promote the growth of erythrocyte, prevents leukopenia, and to treatment glycosuria The diseases such as disease, anemia, hypertension, hyperlipidemia, coronary heart disease, neurasthenia have auxiliary effect.Fructus Mori has promoting the production of body fluid to quench thirst, promotion The effects such as digestion, help defecation, proper amount of edible can promote gastric secretion, stimulates enterokinesia and releases scorching.Motherland's medical science is thought, Fructus Mori are sweet in flavor and cold in property, have the effects such as the liver and the kidney tonifying, intestine moistening of promoting the production of body fluid, black hair improving eyesight.

Before more than 2,000 years, Fructus Mori have been the tonic that Chinese emperors is hired.Because the growing environment that mulberry is special makes sorosis have There are spontaneous growth, feature without any pollution, so Fructus Mori are otherwise known as " holy fruit among the people ".Modern study confirms, Fructus Mori fruit In containing the compositions such as abundant activated protein, vitamin, aminoacid, carotene, mineral, resveratrol, anthocyanidin, nutrition It is 5～6 times of Fructus Mali pumilae, is 4 times of Fructus Vitis viniferae, there is multiple efficacies, be described as " the optimal health-care fruit of 21st century by medical circle Product ".Often eat Fructus Mori and can significantly improve body immunity, there is raising immunity, effect of looks improving and the skin nourishing.

Chinese medicine thinks Fructus Mori sour in the mouth, cold nature, have raising body immunity, YIN nourishing of enriching blood, promoting the production of body fluid to quench thirst, Intestine moistening is dispelled the effect such as dry, cure mainly deficiency of YIN-blood and cause have a dizzy spell, tinnitus cardiopalmus, irritated insomnia, soreness of the waist and knees, beard and hair morning In vain, quench one's thirst only dry, constipation with dry stool, nourishing YIN and supplementing blood, Anshen Bunao, profit joint, curing rheumatism, the effect such as relieve the effect of alcohol.

1, sclerosis of blood vessels is prevented: containing fatty acid in Fructus Mori, mainly by linoleic acid.Stearic acid and oleic acid composition, have point Solve fat, reduce blood fat, prevent the effects such as sclerosis of blood vessels.

2, strengthening the spleen and stomach, aid digestion: containing nutrient substance such as tannic acid, fatty acid, malic acids in Fructus Mori, fat, egg can be helped White matter and the digestion of starch, therefore have the merit that strengthening the spleen and stomach is aid digestion, can be used for the diarrhoea that treatment causes because of dyspepsia.

3, supplement the nutrients: must containing substantial amounts of moisture, carbohydrate, multivitamin, carotene and human body in Fructus Mori The trace element etc. needed, can expand the blood volume of human body effectively, and mends and oiliness, is suitable for hypertension, gynaecological disease patient food Treat.

4, blacking hair and beauty: the nutrient substance wanted containing a large amount of needed by human body in Fructus Mori, possibly together with black hair element, can make hair become Obtain black and glossy, can be used to improve looks.

Ripe Mulberry fruit is nutritious, every 100 grams of Fructus Mori moisture contents 81.8 grams, 1.8 grams of protein, 0.3 gram of fat.Fine Dimension element 4.9 grams, carbohydrate 10 grams, ash 1.2 grams, carotene 30 microgram, thiamine 0.02 milligram, riboflavin 0.06 milli Gram, vitamin E 6.95 milligrams, 33 milligrams of potassium, 0.27 milligram of zinc, copper 0.08 milligram, selenium 4.8 microgram.Additionally, possibly together with tannic acid, Malic acid, vitamin C and fatty acid etc..Its fat predominantly linoleic acid, oleic acid, palmitic acid, stearic acid and a small amount of octanoic acid, nonyl Acid, capric acid, myristic acid, linolenic acid etc..

Chinese medicine odor is poor, and mouthfeel is the best；A lot of people are reluctant to take；Also resisting psychology is produced when allowing people use.How Fructus Mori are sweet, nutritious, the efficacy exertion of defying age to maximum does not the most injure human body, and is obviously improved mouthfeel, enable a person to Accept, be our problem in the urgent need to address.The composition of a large amount of safely and effectively defying age, beauty treatments is contained inside Fructus Mori；Tool There is advantage nontoxic, that can be fully absorbed by organism, be our Main way of studying.

Summary of the invention

The technical problem to be solved is, Chinese medicine odor is poor, and mouthfeel is the best；A lot of people are reluctant to take；Allow Also resisting psychology is produced when people uses.The immunity of modern is just becoming more and more fragile, environmental pollution, works and rests irregular, raw Movable joint plays soon, eat unhealthy, do not know controlling desire, cause the sickness rate of various disease all constantly rising.The most so-called office Room family, the especially group of people at high risk of hypoimmunity.Most people are sub-health states, in overdraw originally with regard to unsound body Body.The symptom of most people is easy catching a cold, eyes are sour and astringent, insufficiency of the spleen weak；Lack of appetite xerostomia；Quench one's thirst；Deficiency of the kidney soreness of the waist and knees；Sexual impotence is lost Essence；Tinnitus mesh is dark；Early whitening of beard and hair；Body void is won thin；Wind favus disease.Kidney essense is the most empty with increasing age for contemporary white collar, and muscle power declines day, mental Going down, Fructus Mori the kidney invigorating essence is improved mental, therefore can Fructus Alpiniae Oxyphyllae keep fit, and experimentation shows that Fructus Mori are improving immunity, the liver and the kidney tonifying There is certain anti-aging effects.The present invention, with Fructus Mori as major ingredient, adds some nourishing the liver and kidney, strengthening the tendons and bones, benefit of invigorating blood circulation marrow, nature and flavor Gentle Chinese medicine, the present invention is obviously improved mouthfeel, and poor for Chinese medicine odor, mouthfeel is the best, in-convenience in use, make the biggest Improve, there is the strongest market prospect；All medicines share tonifying the lung gold, kidney nourishing water, gas of astringing the lung, cough-relieving are breathed heavily, the kidney invigorating essence, improve mental, Therefore can Fructus Alpiniae Oxyphyllae keep fit, human body is had certain anti-aging effects, is a kind of health product improving immunity.

For solving above-mentioned technical problem, the present invention provides a kind of Fructus Mori oral liquid improving immunity, its described Fructus Mori mouth Take liquid and can include the crude drug of following weight portion: Fructus Mori 10～50 parts, Rhizoma Curculiginis 10～20 parts, Radix Rehmanniae Preparata 10～20 parts, Fructus Schisandrae Chinensis 10～20 parts, Herba Taraxaci 10～20 parts, Poria 10～20 parts, Cortex Lycii 10～20 parts, Cortex Acanthopancis 10～20 parts, Radix Polygoni Multiflori Preparata 10～ 20 parts, Fructus Corni 10～20 parts, Herba Taxilli 10～20 parts, Herb Gynostemmae Pentaphylli 10～20 parts, the Radix Astragali 10～20 parts, Herba Sedi 10～20 Part, Radix Codonopsis 10～20 parts, Fructus Ligustri Lucidi 10～20 parts, Semen Cuscutae 10～20 parts, Cortex Moutan 10～20 parts, Fructus Gardeniae 10～20 parts.

The Fructus Mori oral liquid of described raising immunity, its described Fructus Mori oral liquid can also include the raw material of following weight portion Medicine: Fructus Mori 10～40 parts, Rhizoma Curculiginis 10～15 parts, Radix Rehmanniae Preparata 10～15 parts, Fructus Schisandrae Chinensis 10～15 parts, Herba Taraxaci 10～15 parts, Poria 10～15 parts, Cortex Lycii 10～15 parts, Cortex Acanthopancis 10～15 parts, Radix Polygoni Multiflori Preparata 10～15 parts, Fructus Corni 10～15 parts, Herba Taxilli 10 ～15 parts, Herb Gynostemmae Pentaphylli 10～20 parts, the Radix Astragali 10～20 parts, Herba Sedi 10～20 parts, Radix Codonopsis 10～20 parts, Fructus Ligustri Lucidi 10～20 Part, Semen Cuscutae 10～20 parts, Cortex Moutan 10～20 parts, Fructus Gardeniae 10～20 parts.

The Fructus Mori oral liquid of described raising immunity, its described Fructus Mori oral liquid can also include the raw material of following weight portion Medicine: Fructus Mori 10～30 parts, Rhizoma Curculiginis 10～20 parts, Radix Rehmanniae Preparata 10～20 parts, Fructus Schisandrae Chinensis 10～20 parts, Herba Taraxaci 10～20 parts, Poria 10～20 parts, Cortex Lycii 10～20 parts, Cortex Acanthopancis 10～20 parts, Radix Polygoni Multiflori Preparata 10～20 parts, Fructus Corni 10～20 parts, Herba Taxilli 10 ～20 parts, Herb Gynostemmae Pentaphylli 10～15 parts, the Radix Astragali 10～15 parts, Herba Sedi 10～15 parts, Radix Codonopsis 10～15 parts, Fructus Ligustri Lucidi 10～15 Part, Semen Cuscutae 10～15 parts, Cortex Moutan 10～15 parts, Fructus Gardeniae 10～15 parts.

For solving above-mentioned technical problem, the present invention also provides for the preparation method of a kind of Fructus Mori oral liquid improving immunity, The preparation process of its described oral liquid includes:

A. the extraction of Fructus Mori, as component 1；

B. remaining crude drug described is put into heating and refluxing extraction 2 times in ethanol, as component 2；

C. by 2-in-1 also to above two extracting solution component 1 and component, add Mel after concentration or dextrin is in harmonious proportion, after disinfection It is prepared as oral solutions.

In described step a, can gather when annual 4-6 month Fructus Mori fruit maturation, clean, decontamination, dry or slightly steam After dry.

In described step a, farther include, Fructus Mori good for dry in the sun are soaked and has been placed in lid stainless steel cask, add 70% second Alcohol liquid, quality is coarse grained 0.8-1 times, stirs, moistening airtight placement more than 1 hour, makes fully to expand；By percolator Drug sample after moistening expansion is mixed pine after paving and is done to dissipate by bottom filter plate gauze bag parcel again, then contains with rustless steel spoon Powder, loads percolator uniformly, fills 10-12 cm thick, even by T-bar pressure, then presses aforesaid operations, and loading in layer is suitable Working as pressurization, medicated powder loads 2/3 eminence that must not exceed percolator；Medicated powder face upper cover rustless steel orifice plate fastens, and opens under percolator The baiting valve in face, and put a container, then it is slowly added into 70% ethanol；Air between medicated powder powder to be discharged, and have second Alcohol flows out about about 20L, closes baiting valve, covers cylinder of filtering, dipping 24 hours, then opens baiting valve and carries out percolation, controls percolation Speed is generally 1000g medical material outflow per minute 2～3ml, and filtrate puts into liquid container, and pours ethanol during emptying into storage Fluid cylinder；Being merged by percolate and stand, stand for standby use, as component 1.

In described step b, can the medicine of remaining crude drug be put in ethanol, soak 1-2 days, then heating extraction 2 times, 1-2 hour every time, 2 extracting solution are merged and stands；The medicinal residues of the raw medicinal material crossed by above-mentioned ethanol extraction again add water and heat back Stream extracts 2 times, each 1～2 hour, is merged by 2 extracting solution and stands；Being merged by above two extracting solution, concentrating under reduced pressure is relative The filtrate of 1.35 when density is 80 DEG C, reclaims ethanol, and by gained filtrate adjustment proportion to 1.38, reduce pressure to obtain extractum, becomes component 2。

In described step c, can by 2-in-1 to component 1 and component and after, insert in economic benefits and social benefits vacuum concentrator, first that filtrate is dense Being reduced to relative density when 80 DEG C is the concentrated solution of 1.38, sets to 0～5 DEG C of deepfreezes 24 hours；The drainage that cold preservation liquid is added 0.3% Agent kieselguhr, filters, and filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml extractum Han 0.1g, adds dextrin and is in harmonious proportion, disappears Oral liquid it is prepared as after sterilization.

For solving above-mentioned technical problem, the present invention also provides for the preparation method of a kind of Fructus Mori oral liquid improving immunity, Its preparation process can also be:

A. the preparation of Fructus Mori, as component 1；

B. remaining crude drug described chopping is extracted as component 2；

C. component 1 and component 2 are mixed, add proper honey after concentration and be in harmonious proportion, bottle after ultraviolet ray sterilization bactericidal.

In described step a, can steep in ethanol after 1-2 days by the Fructus Mori that dry in the sun is good, heating extraction 2 times, each 1-2 is little Time, taking supernatant, united extraction liquid, 100-110 mesh filters, then the ultrafiltration post ultrafiltration that molecular weight is 6000-10000 through damming, The extractum of 1.36 when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C, heating is concentrated into paste, stand for standby use, becomes component 1；Described In step b, can be mixed by remaining raw medicinal material, shred 100～120 mesh sieves, after sieving, fine powder is standby, and coarse granule is put into resistance to Soda acid infusion kettle, at room temperature, impregnates 3～7 days, then heating and refluxing extraction 2 times, each 1～2 together with more than 70 degree ethanol Hour, 2 extracting solution are merged and stands, filter, after separation, take filtrate；By filtered through gauze, residue adds 50-60% ethanol, 60 DEG C-70 DEG C are continued extraction 2h, every 10min and stir once, and filtered through gauze merges lixiviating solution, and being condensed into pasty state becomes component 2； In described step c, can by 2-in-1 to component 1 and component and after, insert in economic benefits and social benefits vacuum concentrator, be concentrated into when 80 DEG C the closeest Degree is the extractum of 1.60, and the unguentum after concentration adds Mel or dextrin is in harmonious proportion, and bottles after ultraviolet ray sterilization bactericidal.

The present invention organically combines theoretical for modern nutriology with Chinese Traditional Medicine health care theory, debates in view of the traditional Chinese medical science has The characteristic that card opinion is controlled, the advantage that Chinese medicine toxic side effect is little, Chinese medicine health-care treatment causes extensive concern.Fructus Mori sour in the mouth, cold nature, Have raising body immunity, the effect such as dry is dispelled in YIN nourishing of enriching blood, promoting the production of body fluid to quench thirst, intestine moistening, cures mainly deficiency of YIN-blood and the dizzy mesh that causes Dizzy, tinnitus cardiopalmus, irritated insomnia, soreness of the waist and knees, early whitening of beard and hair, quench one's thirst only do, constipation with dry stool, nourishing YIN and supplementing blood, Anshen Bunao, profit Joint, curing rheumatism, the effect such as relieve the effect of alcohol.Modern's irregular health of living is the most empty, and muscle power declines day, amnesia, Fructus Mori the kidney invigorating essence Improve mental, therefore can Fructus Alpiniae Oxyphyllae keep fit, and experimentation shows that Fructus Mori have certain defying age to make at raising immunity, the liver and the kidney tonifying With.The present invention, with Fructus Mori as major ingredient, adds some nourishing the liver and kidney, the Chinese medicine that nature and flavor are gentle, hence it is evident that improve mouthfeel, for Chinese medicine gas Taste is poor, and mouthfeel is the best, in-convenience in use, make the biggest improvement, there is the strongest market prospect；All medicines share tonifying the lung gold, Kidney nourishing water, gas of astringing the lung, cough-relieving are breathed heavily, and the kidney invigorating is smart, it is mental to improve, therefore can Fructus Alpiniae Oxyphyllae keep fit, and has certain anti-aging effects to human body, is A kind of health product improving immunity.

Detailed description of the invention

The health-care effect of Chinese medicine is very strong, if Western medicine easily causes health a large amount of side effect occur, makes people occur bad Reaction, the toxic and side effects effect that is little and that can take for a long time of that Chinese medicine becomes apparent from.

Human immunity is the defensive enginery of human body pathogenic microorganism etc. to external world, or perhaps system of defense, normally In the case of, it ensure that human body is not encroached on by extraneous pathogenic microorganism.The body immunity generally said refers to human body Immune system resists the ability of the infringements such as exotic disease pathogenic microorganism.In the case of body immunity is normal, human body self can Resist the infringement of considerable pathogenic bacteria, it is to avoid human body is caused damage.Immunity plays important work in human life mechanism With, and the nutrition of human body, fatigue, mood, environment, disease, medication, radiation etc. cause the immunity degradation of self.More and more Research shows, the regulation of body immunity is increasingly played a significant role by Chinese medicine.This experimental result shows, the present invention makes tea can Improve cyclophosphamide immunogenicity and decline the organ index of mouse immune organ, macrophages phagocytic capacity and the increment of T cell Ability, the tentative confirmation present invention immunity to hypoimmunity mice of making tea can have potentiation.

Chinese medicine thinks Fructus Mori liver and kidney tonifying, nourishing YIN and benefiting blood, endogenous wind stopping, have cure mainly palpitation and insomnia, have a dizzy spell, tinnitus, The diseases such as constipation night sweat, scrofula, articular instability.Fructus Mori have and improve skin (including scalp) blood supply, nutrition skin, make skin Delicate and black hair etc. acts on, and can improve immunity.Fructus Mori are that middle-aged and elderly people is healthy and strong U.S. face, the good fruit of defying age and good medicine.Often Food Fructus Mori can be with improving eyesight, the symptom that relieving eye strain is dry and astringent.Fructus Mori have immunologic enhancement.Spleen is had weightening finish to make by Fructus Mori With, hemolytic reaction there is is potentiation, human body artery hardening, skeletal joint hardening can be prevented, enhance metabolism.It is permissible Promote the growth of erythrocyte, prevent leukopenia, and to treatment diabetes, anemia, hypertension, hyperlipidemia, coronary heart disease, god Through the disease such as weak, there is auxiliary effect.Fructus Mori has the effects such as promoting the production of body fluid to quench thirst, facilitating digestion, help defecation, proper amount of edible energy Promote gastric secretion, stimulate enterokinesia and release scorching.Motherland's medical science is thought, Fructus Mori are sweet in flavor and cold in property, has the liver and the kidney tonifying, promotes the production of body fluid The effects such as intestine moistening, black hair improving eyesight.

Poria sweet in the mouth, light, property are put down, and are used as medicine and have promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming.Modern medicine grinds Studying carefully: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.Poria slightly sweet flavor is put down, Enter the heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.Dysuria, edema distension, phlegm retention can be controlled Cough with dyspnea, vomiting, malignant histocytosis, have loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.The diuretic of Poria, is to be reached by strong activating the spleen pulmonary function Arrive, different from the Chinese medicine of other direct diuretic.For diarrhea due to hypofunction of the spleen, leukorrhagia Poria can spleen invigorating, again can eliminating dampness by diuresis, for insufficiency of the spleen Have loose bowels caused by dysfunction of the spleen in transportation and transformation, leukorrhagia, application Poria has the effect of giving consideration to both the incidental and fundamental, often and the compatibility such as Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae.Have available For tonifying the lung spleen, control the adjuvant of the deficiency of vital energy.

Fructus Corni, cures mainly pathogen cold and heat under the heart, warming middle-JIAO, by cold temperature numbness, goes three worms, and clothes have been made light of one's life by commiting suicide for a long time, and reinforcing YIN-essence benefit is smart, pacify five The merit of nine orifices, only dribbling urination dirty, logical；Take improving eyesight, strength for a long time all the year round.Fructus Corni, has another name called Fructus Corni, medicine Fructus Jujubae, real Fructus Jujubae, Fructus Jujubae Skin, meat Fructus Jujubae etc., commonly use rare Chinese medicine for China, and applicating history is long.It is gentle with its benefit power, tonifying YANG and do not help fire, YIN nourishing And oiliness diaphragm, convergence and do not stay the special efficacies such as heresy to be liked use by successive dynasties medical science.Zhang Zhongjing has been formulated " golden deficient with Fructus Corni for monarch Shenqi pill ".According to chemical analysis, Fructus Corni contains the stronger cornin of physiologically active, tartaric acid, gallic acid, malic acid, tree The effective ingredient such as ester, tannin and multivitamin, have enhancing immunity, antiinflammatory, the pharmacological action such as antibacterial, are normal in tcm clinical practice Herba indigoferae Pseudotinctoriae.

Radix Rehmanniae Preparata has another name called Radix Rehmanniae Preparata or throws oneself on the ground, and belongs to goatweed, is a kind of first-class Chinese crude drug, has YIN nourishing effect of enriching blood, Can be used for blood deficiency and yellow complexion, dizziness, palpitation and insomnia, menoxenia, the disease such as metrorrhagia, also can be used for the hectic fever hectic fever due to YIN-deficiency of deficiency of kidney yin, robber Antiperspirant, pass out semen, the disease such as quench one's thirst, be one of deficiency syndrome class nonprescription drugs medicine LIUWEI DIHUANG WAN main component.The all cards of the hepatic and renal YIN deficiency, this product Matter is moistened into kidney, and kind nourishing kidney yin, life essence-filling, marrow-benefitting, for the key medicine of tonifying kidney-yin.Ancients call it " big tonifying five ZANG-organs is Kidney-Yin ", and " big benefit is true Water ".Use often it is equal to Rhizoma Dioscoreae, Fructus Corni, the treatment hepatic and renal YIN deficiency, soreness of the waist and knees, seminal emission, night sweat, tinnitus, deafness and quench one's thirst, Can invigorating the liver and kidney, benefit marrow, such as LIUWEI DIHUANG WAN

Radix Trichosanthis is the root of cucurbitaceous plant Chinese juniper beach wormwood, is a kind of Chinese medicine, and for clearing away heat-fire class medicine, its concrete effect is clear Diarrhea of heat type fire, promoting the production of body fluid to quench thirst, evacuation of pus is subsided a swelling.Cure mainly: control that calentura is thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid flaccidity.For controlling Treat diabetes, conventional it with drugs for nourishing yin with the use of, to reach the effect for the treatment of both the principal and secondary aspects of a disease." book on Chinese herbal medicine converges and says ": Radix Trichosanthis, moves back the five internal organs Hot and suffocating, as heart-fire is contained and dry tongue and mouth, lung-fire is contained and pharyngeal swelling sore throat, and spleen-fire is contained and dispute tooth swells, and phlegm-fire is contained and coughed the most peaceful.If The swollen migratory arthralgia caused by wind of the side of body of liver-fire, the hectic fever due to YIN-deficiency dysphoria with smothery sensation of kidney fire, or carbuncle are not burst, and pyretic toxicity does not dissipates, or five types of jaundice yellow skin and eye, and little water If if drenching puckery, it is caused by all burning hot pent-up, only this agent energy relieving stagnation, drops phlegm-fire, and can control it.Its property is sweet cold again, kind can control thirsty, Control from tonic empty thirsty, control fire from the medicine of a cold nature thirsty, control from gas medicine and strongly fragrant yearningly control excessive thirst from blood medicine, be to control thirsty key medicine also.

Rhizoma Curculiginis has reinforcing the kidney and supporting YANG, benefiting essence-blood, bone and muscle strengthening and the effect of promoting the circulation of blood detumescence, is mainly used in insufficiency of kidney-YANG, sexual impotence The diseases such as seminal emission, chronic consumptive disease internal injury and bones and muscles pain.Kidney-replenishing, bone and muscle strengthening, cold expelling is wet.Control sexual impotence cold sperm, urinary incontinence, metrorrhagia, Trusted subordinate's cold type of pain, cold arthralgia of loins and legs, carbuncle, scrofula, yang deficiency cold diarrhea.Sexual impotence essence is trembled with fear, the diseases such as waist knee joint is air-cooled, muscles and bones flaccidity syndrome and arthralgia syndrome.Ancient prescription has Rhizoma Curculiginis ball, can strengthening bone and muscle, benefit spirit, improving eyesight, black beard and hair." Haiyao Bencao, Oversea Materia Medica ": main air, mends and warms up waist foot, clear settling five organs, bone and muscle strengthening, Help digestion.Declare and mend again, main husband's seven kinds of impairments, bright knowledge, benefit biceps, fill out bone marrow, Yiyang." Japan hanako materia medica ": control all pathogenic wind, mends Five kinds of strain and seven kinds of impairment, the therapeutic method to keep the adverse QI flowing downwards of whetting the appetite.

Cortex Lycii is cold in nature, sweet in the mouth.Function cures mainly: removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, lung-heat Cough, spitting of blood, epistaxis.Heat clearing away, removing heat from blood.Control asthenia hectic fever night sweat, lung-heat cough with asthma, spit blood, epistaxis, stranguria with blood, quench one's thirst, hypertension, Carbuncle, malignant boil." herbal classic ": " pathogen in main five, hankers quenching one's thirst, general arthralgia." " not Lu ": " main air is wet, lower breast side of body gas, and exopathogenic heat is had a headache, Mend internal injury great Lao to hiss suctions, hard muscle, reinforcing YIN-essence, sharp intestine and small intestine, resistance to cold and summer-heat.″

Cortex Acanthopancis is the root bark being dried of Araliaceae machaka acanthopanax gracilistylus.Have another name called Cortex Acanthopanacis Radicis, mesh bone, chase after wind make, south Cortex Acanthopancis etc..Main product in Hubei, Hunan, Henan, Anhui, the ground such as Sichuan.Chinese medicine Cortex Acanthopancis has wind-damp dispelling, invigorating the liver and kidney, strong muscle The effects such as bone.Described in Compendium of Material Medica: " invigorating the spleen and replenishing QI, dispelling the wind and dampness pathogens flaccidity syndrome and arthralgia syndrome, strengthening bone and muscle." modern study, this product also has anti- Tumor, resisting fatigue, reduction whole blood viscosity, atherosclerosis formation etc. act on.Cortex Acanthopancis is easy to use, decoct soup, enter ball, Dissipate or leaching slender acanthopanax bark spirit, but hyperactivity of fire caused by deficiency of YIN person is cautious use of.

Herba Taxilli is bitter；Sweet；Property flat.There are wind-damp dispelling, liver and kidney tonifying, bone and muscle strengthening, antiabortive effect.Enter the heart, kidney two warp.Function master Control: invigorating the liver and kidney；Bone and muscle strengthening；Wind-damp dispelling；Antiabortive.Main soreness of waist and knee joint；Muscles and bones flaccidity is weak；Limbs are hemiplegia；Rheumatic arthralgia；Head is wrong dizzy； Frequent fetal movement, metrostaxis.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, metrorrhagia through many, blood leaking in gestation, frequent fetal movement； Hypertension.

The Radix Paeoniae Alba is cool in nature, bitter in the mouth acid, is slightly cold, has easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving.Yin fluid astringing receives the effects such as antiperspirant, it is adaptable to the deficiency of YIN Heating, menoxenia, the chest and abdomen pain over the hypochondriac region, extremity contraction urgency, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band.Paeoniflorin has Antibacterial, antipyretic, antiinflammatory, increase coronary flow, improve myocardial nutritional flow, expansion blood vessel, antagonism acute myocardial ischemia, press down Platelet aggregation processed, calmness, analgesia, spasmolytic, antiulcer, the effect of regulation blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, pneumonia Streptococcus, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc..The blood deficiency deficiency of YIN, the chest and abdomen pain over the hypochondriac region, hepatic region Bitterly, cholecystitis, gallstone pain, dysentery stomachache, women's menalgia, spontaneous perspiration easy antiperspirant night sweat, sural spasm, spasm of the limbs pain Bitterly, the condition subject such as uneasy lower limb syndrome suitably eats.

Radix Polygoni Multiflori Preparata be will Radix Polygoni Multiflori and Semen sojae atricolor with the Radix Polygoni Multiflori dried after boiling, simply invigorating the liver and kidney, benefiting essence-blood, nourish heart and allay excitement Good medicine.Be mainly used in treating cause because of deficiency of the liver and kindey, essence and blood loss soreness of the waist and knees, dizziness and blurred vision, palpitation and insomnia, hair early Wait disease in vain.The black hair function of Radix Polygoni Multiflori is to be brought into play by the kidney invigorating, benefit essence, the effect allayed excitement of nourishing blood.Radix Polygoni Multiflori Preparata has benefit Benefiting essence-blood, nourishing the liver calms the nerves, bone and muscle strengthening, reinforce the kidney crow must, see Light-headedness for blood deficiency, palpitation and insomnia is forgetful, sallow weak, liver The vertigo and tinnitus of kidney blood and essence asthenia, soreness of the waist and knees, the diseases such as metrorrhagia and leukorrhagia, early whitening of beard and hair of passing out semen.Radix Angelicae Sinensis

Radix Salviae Miltiorrhizae is bitter, is slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea pain Warp, lump in the abdomen, chest and abdomen twinge, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia.For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen is tied Block, skin infection swells and ache, and tumbling down is grieved, menoxenia, amenorrhea dysmenorrhea, puerperal stasis of blood pain etc..Treatment costa sternales pain, lump in the abdomen caking, and Menoxenia, amenorrhea dysmenorrhoea have good effect." detailed outline " carries: Radix Salviae Miltiorrhizae, and by " the sensible opinion of married woman " cloud, SIWU TANG is controlled gynecopathy, paid no attention to Antenatal puerperal, how many through water, the most generally applicable, only taste Radix Salviae Miltiorrhizae dissipates, and cures mainly same.Lid Radix Salviae Miltiorrhizae can break stagnated blood, mends fresh blood, peace Green tire, fall stillborn fetus, only metrorrhagia dysentery, regulating menstruation arteries and veins.Main Compositions of Radix Salviae Miltiorrhizae TANSHINONES has expansion blood vessel, improves circulation, releasing blood vessel Intravascular coagulations etc. act on, and have effect of invigorating blood circulation trace, and can promote that liver blood circulates, beneficially liver cell regeneration.

The Radix Astragali has the effects such as invigorating QI to consolidate the body surface resistance, diuretic detumescent, expelling pus and toxin by strengthening QI, granulation promoting.The medicinal of the Radix Astragali has 2000 so far History for many years, modern study, the Radix Astragali is containing lot of traces such as Saponin, sucrose, polysaccharide, several amino acids, folic acid and selenium, zinc, copper Element.Have enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and wide antibacterial action.But table is real Evil containing, retention of dampness due to stagnation of QI, food stagnation is stagnated, carbuncle from the beginning of or the excess syndrome such as pyretic toxicity Shang Sheng after bursting.The Radix Astragali has invigorating QI to consolidate the body surface resistance, diuresis torr Poison, evacuation of pus, effect of expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency Spontaneous perspiration, carbuncle difficulty is burst, and bursts for a long time and does not holds back, and blood deficiency and yellow complexion, interior-heat is quenched one's thirst." herbal classic " is recorded: " main carbuncle loses skin ulcer, evacuation of pus pain relieving for a long time. Qi-restoratives, children's's all kinds of diseases and ailments." " Japan hanako materia medica " record: " help gas strengthening bone and muscle, put on flesh and enrich blood.”

Fructus Ligustri Lucidi, sweet-bitter flavor, cool in nature, return Liver and kidney warp, there is nourishing the liver and kidney, merit that tonifying YIN nourishes blood.Modern medicine study is demonstrate,proved Bright, Fructus Ligustri Lucidi includes ursolic acid, mannitol, glucose, fatty oil etc., has heart tonifying, diuresis and hepatoprotective effect, can make because chemotherapy is drawn The leukopenia quantity risen raises, and staphylococcus aureus, escherichia coli are had inhibitory action.Containing neat pier in Fructus Ligustri Lucidi The acid of fruit acid Fructus Ligustri Lucidi, nuezhenoside, ursolic acid, stearic acid, oleic acid, mannitol, betulin, phospholipid and saccharide such as Fructus Ligustri Lucidi are many Sugar, arabinose, glucose etc., possibly together with 15 kinds of aminoacid, 11 kinds of trace element and volatile oil etc..Research thinks that Fructus Ligustri Lucidi has Blood sugar lowering and blood fat reducing also have study of anti-atherogenic effect, the most antibacterial, antivirus action, and Fructus Ligustri Lucidi decoct is to golden yellow Portugal Grape coccus, shigella flexneri, Bacillus typhi, bacillus pyocyaneus and escherichia coli all have inhibitory action.Type B adenovirus is had medium Degree inhibitory action.Leukocyte increasing: Fructus Ligustri Lucidi and component preparation thereof all have certain impact to hemocyte, it is to white caused by chemotherapy Cell declines rising effect.Compound recipe containing Fructus Ligustri Lucidi also has effect in increasing leukocyte.Anti thrombotic action: oleanolic acid can accelerate blood The mobility of platelet cell, reduces the collision between platelet, is allowed to be difficult to adhesion and gathering, is less susceptible to sink in tunica intima Long-pending, slow down or prevent thrombosis, the deposition of lipid inner membrance can be reduced again, the thrombotic disease for preventing and treating old people provides portion Divide experimental basis.Defying age improves immunity: Fructus Ligustri Lucidi decoct can make mouse immune organ thymus, spleen weight increase；Substantially Improving mice serum hemolytic antibody activity, the impact that mouse spleen lymphocyte produces interleukin-2 has two-ways regulation work With.Fructus Ligustri Lucidi has significant immunological enhancement, removes free radical thus defying age.Application Fructus Ligustri Lucidi preventing and treating: cardiovascular disease Disease, coronary heart disease, hyperlipemia, diabetes, thrombocytopenia, leukopenia, chronic nephritis, chronic bronchitis, stupid Solidity insomnia, Chronic Benzene Poisoning, tumor, malnutrition, immunologic hypofunction disease, seborrheic dermatitis

Fructus Schisandrae Chinensis contains abundant organic acid, vitamin, flavonoid, phytosterol and has the lignan of potent reactivation (such as schisandrin, schisandrin B or Fructus Schisandrae Chinensis fat element), it is also to have essence, gas, the minority medical material of god's three big tonifications concurrently One of, the energy strong liver of QI invigorating, enhancement cell get rid of the efficiency of refuse, supply more oxygen, build and use energy, raising memory And property endurance.In ancient times, Russia hunter must take Fructus Schisandrae Chinensis to keep fit QI invigorating before going on a long journey hunting every time.Fructus Schisandrae Chinensis has There is outstanding effect, including: 1, protect the liver and regenerate liver organization.Liver is the maincenter removing toxic substances organ of human body, is responsible for filtering Noxious substance, in order to avoid damaging human body.Fructus Schisandrae Chinensis has antiinflammation, and Fructus Schisandrae Chinensis has antiinflammation, to prevent liver Damage, activate anabolic process with promote wounded hepatocytes reparation, and can strengthen DNA (DNA) synthetic and The activity of ornithine decarboxylase, regenerates liver cell.Carbon tetrachloride (CCl4) is the material that liver is most poisoned by one of which. Countless research shows, the potent liver-protecting efficacy of Fructus Schisandrae Chinensis can resist the toxic action of CCl4.As can be seen here, Fructus Schisandrae Chinensis is in protection Liver has the biggest effect from daily toxin infringement aspect.

Herba Taraxaci nature and flavor are sweet, micro-hardship, cold.Return liver, stomach warp.There are the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.Control pyretic toxicity, Carbuncle, skin infection, abscess of internal organ, conjunctival congestion and swelling pain, damp and hot, the puckery pain of jaundice, dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, conjunctival congestion, Pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctiva Inflammation, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection etc..Herba Taraxaci can be given birth to Eat, stir-fry and eat, cook soup, be the plant of dietotherapeutic.

Herba Sedi, Chinese medicine name.Dry herb for crassulaceae plants Herba Sedi.Sweet, light, cool.There are dampness removing jaundice eliminating, heat clearing away solution Effect of poison.It is usually used in jaundice due to damp-heat, dysuria, carbuncle skin infection.Return liver, gallbladder, small intestine meridian.Effect dampness removing jaundice eliminating, heat clearing away solution Poison.Cure mainly for jaundice due to damp-heat, dysuria, carbuncle skin infection.

The main active ingredient of Herb Gynostemmae Pentaphylli be gypenoside, Herb Gynostemmae Pentaphylli glucoside (polysaccharide), water-soluble amino acid, flavonoid, Multivitamin, trace element, mineral etc..Medical material Ji Yuan: for the herb of cucurbitaceous plant Herb Gynostemmae Pentaphylli.Nature and flavor: bitter in the mouth；Micro- Sweet；Cool in nature.Gui Jing: return lung；Spleen；Kidney channel.Effect: replenishing QI to invigorate the spleen, preventing phlegm from forming and stopping coughing, heat-clearing and toxic substances removing.Effect is classified: qi-restoratives medicine；Change Expectorant medicine；Antipyretic.Cure mainly: body void is weak；Nephrasthenia emission；Leukopenia；Hyperlipemia；Viral hepatitis；Chronic gastrointestinal Scorching；Chronic tracheitis.

Radix Codonopsis is traditional tonic that China is conventional, and ancient times are top grade with the Radix Codonopsis that area, Shangdang, Shanxi produces, and have benefit Middle QI invigorating, effect of strengthening spleen and tonifying lung.Radix Codonopsis has enhancing immunity, expansion blood vessel, blood pressure lowering, improves microcirculation, enhancing hemopoietic function Deng effect.In addition the leukopenia caused chemotherapy radiotherapy has castering action.

Semen Cuscutae Cuscuta chinensis is dicotyledon scammonia section plant Semen Cuscutae, Cuscuta australis, cuscuta japonica Choisy etc. Seed, can the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, effect of solid tire stopping leak.Nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For Impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen kidney vaginal bleeding during pregnancy, fetal movement Uneasy, spleen is suffered from a deficiency of the kidney and is rushed down；Externally treating leucoderma.Former medicine sieve is removed spare, picks decontamination, dry

Fructus Gardeniae bitter cold, can blood system and clear pathogen is warm, wide intestinal relieving constipation, anti-cancer, Flos Gardeniae contains cellulose, can prevent hemorrhoid Make and the generation of rectum carcinoma.Radix Gardeniae, leaf, fruit all can be used as medicine, and have pathogenic fire purging relieving restlessness, and antiinflammatory is dispelled heat, clearing away heat and promoting diuresis, external Effect of removing toxic substances.Flos Gardeniae, fruit, leaf and Gen Ke are used as medicine, and typically make tea or decoct soup clothes.Fructus Gardeniae containing gardenoside, geniposide, Herba Paederiae time glycoside methyl ester and a small amount of shanzhiside, have that clearing away heat and promoting diuresis, external removing toxic substances, jaundice, stranguria with blood pain be the most puckery, the red and swollen pain of mesh, fire-toxin skin ulcer, The effects such as blood pressure lowering.Wherein fruit of Fructus Gardeniae is used as medicine, and cures mainly calentura hyperpyrexia, dysphoria and insomnia, and excess-fire is had a toothache, aphtha of the mouth and tongue, and nose is advised, told Blood, eye conjunctivitis, sore swollen toxin, icteric infectious hepatitis, favism, hematuria；Traumatic hemorrhage, bruise are controlled in external.Root enters Medicine cures mainly infectious hepatitis, traumatic injury, acute toothache.Compendium of Material Medica claims it, and " improving healthy complexion, it is used by " a thousand pieces of gold wing " face cream.” " the southern regions of the Yunnan Province book on Chinese herbal medicine " claims its " purte the white, only cough due to lung-heat, only epistaxis blood, expectorant." meridian distribution of property and flavor: cold in nature, sweet-bitter flavor；Enter lung, liver Warp.Effect: clearing away lung-heat to relieve cough, external is stopped blooding.Cure mainly cough due to lung-heat, nose, cough up phlegm, the disease such as toxic swelling.Main component: Flos Gardeniae Containing Triterpenoid, Fructus Gardeniae flower acid A, B and son acid.Containing volatile oil, including benzyl acetate, linalyl acetate, another containing pigment glycoside, wood Honey alcohol etc..It addition, possibly together with carbohydrate, protein, crude fibre and multivitamin.

The specific embodiment of the invention

Specific embodiment 1:

Gather during annual 4-6 month Fructus Mori fruit maturation, clean, decontamination, dry after drying or slightly steaming.

The Fructus Mori that dry in the sun is good are steeped in 10 times amount ethanol, soak more than 2-5 days, heating extraction 2 times, become component 1.

By remaining crude drug Rhizoma Curculiginis, Radix Rehmanniae Preparata, Fructus Schisandrae Chinensis, Herba Taraxaci, Poria, Cortex Lycii, Cortex Acanthopancis, Radix Polygoni Multiflori Preparata, Fructus Corni, Herba Taxilli, Herb Gynostemmae Pentaphylli, the Radix Astragali, Herba Sedi, Radix Codonopsis, Fructus Ligustri Lucidi, Semen Cuscutae, Cortex Moutan, Fructus Gardeniae, put in weight 10 times amount ethanol, Soak more than 2-5 days, heating extraction 2 times, become component 2.

By 2-in-1 to component 1 and component and after insert in economic benefits and social benefits vacuum concentrator, the unguentum after concentration add Mel be in harmonious proportion, ultraviolet Bottle after line disinfection.

Specific embodiment 2: gather during annual 4-6 month Fructus Mori fruit maturation, cleans, decontamination, dries after drying or slightly steaming. About 5000g.Being soaked by Fructus Mori 5000g good for dry in the sun and be placed in lid stainless steel cask, add 70% ethanol, quality is coarse granule 0.8-1 times, stir, moistening airtight placement more than 1 hour, make fully to expand；By filter plate gauze bag bottom percolator Drug sample after moistening expansion is mixed pine and is done to dissipate by parcel again after paving, then contain powder with rustless steel spoon, load percolation uniformly Cylinder, fills 10-12 cm thick, even by T-bar pressure, then presses aforesaid operations, and loading in layer is suitably pressurizeed, and medicated powder loads not 2/3 eminence of percolator must be exceeded；Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts one Container, is then slowly added into 70% ethanol；Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close Close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, control percolation speed and be generally 1000g medical material Outflow 2～3ml per minute, filtrate is put into liquid container, and is poured ethanol during emptying into liquid container；Percolate is merged quiet Put, stand for standby use, as component 1.By Rhizoma Curculiginis 1200g, Radix Rehmanniae Preparata 1300g, Fructus Schisandrae Chinensis 1300g, Herba Taraxaci 1200g, Cortex Lycii 1200g, Radix Polygoni Multiflori Preparata 1200g, Fructus Corni 1200g, Herba Taxilli 1200g, Herb Gynostemmae Pentaphylli 1200g, Radix Astragali 1200g, Herba Sedi 1200g, Radix Codonopsis 1200g, Fructus Ligustri Lucidi 1200g, Semen Cuscutae 1200g, Cortex Moutan 1200g, Fructus Gardeniae 1200g, put in weight 10 times amount ethanol, leaching Steep 15 days, then heating extraction 2 times, each 1-2 hour, united extraction liquid, take supernatant after standing, be then placed in concentrating under reduced pressure In tank, decompression recycling ethanol, being concentrated into liquor strength is 0.6g crude drug/mL, when the relative density of sucking filtration to filtrate is 20 DEG C The extractum of 1.06, becomes component 2.By 2-in-1 to component 1 and component and after, insert in economic benefits and social benefits vacuum concentrator, first concentrate the filtrate to When 80 DEG C, relative density is the concentrated solution of 1.38, sets to 0～5 DEG C of deepfreezes 24 hours；The filter aid silicon that cold preservation liquid is added 0.3% Diatomaceous earth, filters, and filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml extractum Han 0.1g, adds dextrin and is in harmonious proportion, and sterilization is killed Oral liquid it is prepared as after bacterium.

Specific embodiment 3: gather during annual 4-6 month Fructus Mori fruit maturation, cleans, decontamination, dries after drying or slightly steaming. Fructus Mori 4000g good for dry in the sun is steeped in 10 times amount ethanol, soak 15 days, heating extraction 2 times, each 1-2 hour, take supernatant Liquid, united extraction liquid, 100-110 mesh filters, then the ultrafiltration post ultrafiltration that molecular weight is 6000-10000 through damming, and ultrafiltrate reduces pressure Concentrating the extractum of 1.36 when relative density is 80 DEG C, heating is concentrated into paste, stand for standby use, becomes component 1.By Rhizoma Curculiginis 110g, ripe Ground 110g, Fructus Schisandrae Chinensis 110g, Herba Taraxaci 1200g, Cortex Lycii 1200g, Radix Polygoni Multiflori Preparata 1200g, Fructus Corni 1200g, Herba Taxilli 1200g, Herb Gynostemmae Pentaphylli 1200g, Radix Astragali 110g, Herba Sedi 110g, Radix Codonopsis 1200g, Fructus Ligustri Lucidi 1200g, Semen Cuscutae 110g, Cortex Moutan 1200g, Fructus Gardeniae 1200g, mix remaining raw medicinal material, shredded 100～120 mesh sieves, and after sieving, fine powder is standby, and coarse granule is put Enter acid and alkali-resistance infusion kettle, at room temperature, impregnate together with more than 70 degree ethanol 2～4 days, then heating and refluxing extraction 2 times, every time 1～2 hour, 2 extracting solution are merged and stands, filter, after separation, take filtrate；By filtered through gauze, residue adds 50-60% second Alcohol, 60 DEG C-70 DEG C are continued extraction 2h, every 10min and stir once, and filtered through gauze merges lixiviating solution, and being condensed into pasty state becomes component 2.By 2-in-1 to component 1 and component and after insert in economic benefits and social benefits vacuum concentrator, when being concentrated into 80 DEG C, relative density is the concentration of 1.50 Liquid, sets to 0～5 DEG C of deepfreezes 24 hours；The filter aid kieselguhr adding 0.3% by cold preservation liquid, filters, and it is true that filtrate inserts economic benefits and social benefits again In empty concentrator, it is concentrated into every 1ml containing 0.1 amount；Unguentum after concentration adds dextrin and is in harmonious proportion, and bottles after ultraviolet ray sterilization bactericidal.

Specific embodiment 4: gather during annual 4-6 month Fructus Mori fruit maturation, cleans, decontamination, dries after drying or slightly steaming. About 3500g.Fructus Mori 3500g good for dry in the sun is steeped in 10 times amount ethanol 2 days, heating extraction 2 times, each 1-2 hour, take Clear liquid, united extraction liquid, 100-110 mesh filters, then the ultrafiltration post ultrafiltration that molecular weight is 6000-10000 through damming, and ultrafiltrate subtracts Pressure concentrates the extractum of 1.36 when relative density is 80 DEG C, and heating is concentrated into paste, stand for standby use, becomes component 1.Just Rhizoma Curculiginis 110g, Radix Rehmanniae Preparata 110g, Fructus Schisandrae Chinensis 110g, Herba Taraxaci 1200g, Cortex Lycii 1200g, Radix Polygoni Multiflori Preparata 1200g, Fructus Corni 1200g, Herba Taxilli Raw 1200g, Herb Gynostemmae Pentaphylli 1200g, Radix Astragali 110g, Herba Sedi 110g, Radix Codonopsis 1200g, Fructus Ligustri Lucidi 1200g, Semen Cuscutae 110g, Cortex Moutan 1200g, Fructus Gardeniae 1200g, after described crude drug is put into pulverizer pulverizing, put into heating and refluxing extraction 2 in ethanol by particulate matter Secondary, each 1～2 hour, 2 extracting solution are merged and stands；The medicinal residues that above-mentioned ethanol extraction is crossed add 10 times amount water be heated to reflux Extract 2 times, each 1～2 hour, 2 extracting solution are merged and stands, above two extracting solution is merged, as component 2；Merge The filtrate of 1.50 when component 1 component 2 concentrating under reduced pressure relative density is 80 DEG C, reclaims ethanol, calls in dextrin or Mel, and ultraviolet kills Bottle after bacterium.

Pharmacological toxicity is tested

Experimental example 1: acute toxicity test of the present invention

One, test material: animal: Kunming mouse, body weight 19-26g, male and female half and half, Shandong University's biology laboratory is educated Kind.Medicine: the present invention (all raw material mixing decocts 2 times, merges and filters, taking liquid) is containing 0.0365mg/ml.

Two, method:

1, LD50 calculates: using improvement karber's method, mice is randomly divided into 5 groups, often group 10, male and female half and half, by this The bright distilled water that adds dissolves, and is made into Cmax, is administered by the maximum allowable capacity of mice, and institute is followed successively by 18 to dosage by crude drug amount, 14.4,11.5,9.2,7.4 (g.kg-1), after animal fasting (can't help water) 18 hours, are administered (interval half at twice in one day Hour), each 0.5ml, observes animal dead situation.

2, maximum tolerated dose measures (MTD value): take mice 20, each 10 of male and female.The present invention adds distilled water dissolve, It is made into maximum concentration, by the maximum tolerated dose of animal, can twitch with injection filling hello device and be as the criterion.Little at animal fasting (can't help water) 18 Shi Hou, is administered (interval half an hour) in one day at twice, each 0.5ml (every ml 0.36g Han crude drug), total dose be 18g crude drug/ Kg.d, 300 times of quite clinical adult's 50Kg body weight consumption.Continuous Observation 7 days after administration.

Three, result of the test:

In LD50 calculates when giving mice with maximum acceptable concentration and maximum allowable capacity (18g/Kg.d), have no little Mus is dead, does not i.e. measure LD50, seeks maximum tolerated dose only, in 7 day observation period, and its appetite of animal, activity, hair color, essence God's states etc. are all normal, grow normal, there are no death.I.e. select and be equivalent to 300 times of doses of clinical dosage, there is no bad instead Should occur, show that acute toxicity is minimum, MTD ＞ 18g/Kg.d.

Experimental example 2: acute toxicity and the result of the test of long term toxicity

Acute toxicity test: give the present invention, maximum concentration 35%, maximum gavage capacity by the disposable gavage of white mice 0.4ml/10g, dosage 14g/kg (every g medicated powder is equivalent to 10g crude drug), Continuous Observation 7 days, do not find any toxic reaction, because of Concentration and dosage cannot increase, therefore fail to measure the LD 50 of this medicine.Maximum tolerance determination: with maximum concentration, maximum gavage is held Amount, mice lavage is administered 3 times, is spaced 5 hours, then Continuous Observation 7 days, and none example is dead.Medicated powder dosage is ＞ 42g/kg. Day (every g medicated powder is equivalent to 10g crude drug), is calculated 420 times of the clinical consumption per day that is equivalent to be grown up by kg body weight.

Long term toxicity test: for observing whether long-term prescription produces toxic reaction, give the rat present invention respectively and raise clothes, press 70 times and 35 times (i.e. 7g/kg/ day and 3.5g/kg/ days) of the clinical consumption per day of adult, continuous feeding 8 weeks, have no the row of rat Occurring abnormal for, feed, body weight, with matched group ratio, routine blood test, hepatic and renal function, the change the most without exception of various important organs, in institute In the range of dosage, not it has been found that any toxicity of the present invention.Confirmed by the acute and chronic toxicity test of animal, this Bright safety range is relatively big, is a kind of safe and reliable health product.

Pharmacodynamic experiment:

To immunoregulation effect

Using Immunology Today theory and technology, Study of Traditional Chinese Medicine is to strengthening and the effect of regulation body's immunity, and this is to explaining The bright material base about theory of Chinese medical science has highly important meaning.The present invention is joined through science by several natural drugs such as Fructus Mori 5 form.Existing research finds, the function of oral liquid adjustable body of the present invention each system internal organs, to immunocyte and immunity Molecule all has regulation effect, has the immunity that improves.Inquire into now oral liquid of the present invention further with experiment to exempting from The molecular immunology mechanism of epidemic disease power low mouse immune regulation effect.

1 materials and methods

1.1 instruments are provided by preparation section of the court with reagent oral liquid of the present invention；Primary raw material has: Fructus Mori, Rhizoma Curculiginis, Radix Rehmanniae Preparata, Fructus Schisandrae Chinensis, Fructus Rubi, Poria, Cortex Lycii, Cortex Acanthopancis, Radix Polygoni Multiflori Preparata, Fructus Corni, Herba Taxilli, prepare by the method for embodiment 2.Note Penetrate and provided by Hualian Pharmaceutical Co., Ltd., Shanghai with cyclophosphamide.Cytokine detection kits is all purchased from R&D company of the U.S..Stream Formula cell instrument, 2000FCA, U.S. company BD production.

1.2 animal Kunming system male mices 30, in 6-8 week, body weight is 25 ± 2g, by the limited duty of Shandong University's laboratory animal Ren company provides.

1.3 method

1.3.1 Kunming system male mice is randomly divided into 3 groups with packet by Animal Model: blank group, model group With medicine group, often group 10.Blank group: in experiment process, any process is not made in normal raising；Model group: intraperitoneal injection 100mg/kg cyclophosphamide causes hypoimmunity model, 1 time/d, for three days on end；Medicine group: intraperitoneal injection 100mg/kg ring Phosphamide causes hypoimmunity model, 1 time/d, for three days on end, and within first day, smears administration at the left tibialis anterior of mice in modeling, Only, booster immunization 1 time after a week, dosage is with for the first time for 0.1mL/.Collecting sample after 4d.

1.3.2, after the mensuration mice of mouse immune shoot formation weighs in, cervical dislocation puts to death mice, takes thymus, spleen Its weight in wet base of dirty title, calculating thymus index and spleen index:

Thymus index=chest gland weight × 1000/ body weight

Spleen index=spleen weight × 1000/ body weight

The mensuration of 1.3.3 mice serum IgG, IgM level presses test kit description method, measures IgG in mice serum, IgM content.

1.3.4 mouse boosting tissue T lymphocyte and subgroup CD4+ thereof, the mensuration of CD8+ and CD4+/CD8+ is aseptic takes spleen, puts In filling in right amount without, in Hank ' s liquid plate, being ground by spleen gently with tweezers, make single born of the same parents' suspension, filter through 200 eye mesh screens, By cell suspension in the complete culture solution of 1mL, adjust cell concentration 1 × 109L^-1, with micropipettor carefully by 100 μ L The fully splenocyte suspension of mixing is added to the bottom of sample feeding pipe, adds 20 μ L monoclonal antibodies, low-speed oscillation mixing 3S, room temperature lucifuge Hatch 30min, after countler-PREP broken red blood cell, flow cytometer detection T cell subgroup content.

1.3.5 mice serum IFN-Y, IL^-10The mensuration of level presses test kit description method, measure IFN-Y in serum, IL^-10Level.

The 1.2 all numerical value of statistical procedures all represent with x ± s, use SPSS13.0 statistical software to carry out data analysis, group Between compare employing t inspection.Using P ＜ 0.05 as statistical significant difference standard.

2 results

The impact of hypoimmunity mouse immune organ is drawn by 2.1 by table 1, compared with Normal group, and model group spleen Dirty and thymus index significantly reduces, and difference is statistically significant, P ＜ 0.01.Compare with model group, medicine group mouse spleen index Substantially increasing, have statistical significance, P ＜ 0.01, thymus index also increased, but difference is the most notable.

Table 1 present invention on hypoimmunity mouse immune organ weight impact (n=10, mean ± S)

Compare with Normal group: Δ: P ＜ 0.05, Δ Δ: P ＜ 0.01；Compare with model group: *: P ＜ 0.05, * *: P ＜ 0.01

The impact of hypoimmunity mouse boosting tissue T lymph subgroup is found out by 2.2 by table 2, compared with Normal group, and mould Type group mouse spleen CD4+ cell subsets percentage drop, CD8+ cell subsets percentage ratio rises, has significant difference, P ＜ 0.05, CD4+/CD8+ ratio substantially reduces, and has pole significant difference, P ＜ 0.01.And medicine group can substantially offset ring phosphinylidyne Amine destroys the effect of immunity, has significant difference, P ＜ 0.05.

Table 2 present invention on hypoimmunity mice body fluid T cell subgroup impact (n=10, mean ± SD)

Compare with Normal group: Δ P ＜ 0.05, Δ Δ P ＜ 0.05；With than model group: * P ＜ 0.05, * * P ＜ 0.05.

Thymus, spleen are the important lymphatic organ of body.Thymus is that T cell is grown, differentiation, ripe place, its structure And function is closely related with fuselage state.The reduction of thymus index and atrophy of thymus gland, be all that mice is based on cellular immunization Immunosuppressant shows.Spleen is the peripheral immune organ of internal maximum, and the immunocyte of spleen is based on bone-marrow-derived lymphocyte, and B Lymphocyte is the main cell participating in humoral immunization, and therefore spleen and humoral immunity of organism is in close relations.Thymus index and Spleen index has reacted the power of immune body function intuitively.This experiment shows, caused by cyclophosphamide is exempted from by oral liquid of the present invention The growth of the low mouse spleen of epidemic disease power has facilitation, and the growth to thymus also has certain facilitation.

Modern medicine study shows, old and feeble essence is the decline of stem cell, the decline of immunity, tissue organ function Degeneration, the decline of defying age gene；Therefore, scientist thinks the immunity of human body to be improved, and the most basic way is to delay people The aging course of body.It is alive for evermore to pursue, and delays life, is mankind's dreams for thousands of years, and human sciences family is the most long-term and unremitting Ground research is about the problem of Human Longevity.This experiment confirms from a side, and the present invention can significantly improve immunity level, and then Aging can be effective against further.

Containing fatty acid in Fructus Mori, mainly by linoleic acid.Stearic acid and oleic acid composition, have and reduce fat, reduce blood fat, Prevent the effects such as sclerosis of blood vessels.Strengthening the spleen and stomach is aid digestion: containing nutrient substance such as tannic acid, fatty acid, malic acids in Fructus Mori, to help Help the digestion of fat, protein and starch, therefore have the merit that strengthening the spleen and stomach is aid digestion, can be used for the abdomen that treatment causes because of dyspepsia Rush down.Containing substantial amounts of moisture, carbohydrate, multivitamin, carotene and the trace element etc. of needed by human in Fructus Mori, Can effectively expand the blood volume of human body, and mend and oiliness, be suitable for hypertension, gynaecological disease patient's dietetic therapy.Containing big in Fructus Mori The nutrient substance that amount needed by human body is wanted, possibly together with black hair element, can make hair become black and glossy, can be used to improve looks.Ripe Mulberry Sorosis is nutritious, every 100 grams of Fructus Mori moisture contents 81.8 grams, 1.8 grams of protein, 0.3 gram of fat.Cellulose 4.9 grams, carbon aquation Compound 10 grams, ash 1.2 grams, carotene 30 microgram, thiamine 0.02 milligram, 0.06 milligram of riboflavin, vitamin E 6.95 milli Gram, 33 milligrams of potassium, 0.27 milligram of zinc, copper 0.08 milligram, selenium 4.8 microgram.Additionally, possibly together with tannic acid, malic acid, vitamin C and Fatty acid etc..Its fat predominantly linoleic acid, oleic acid, palmitic acid, stearic acid and a small amount of octanoic acid, n-nonanoic acid, capric acid, myristic acid, Linolenic acid etc..Add tonifying the lung gold again, kidney nourishing water, gas of astringing the lung, cough-relieving are breathed heavily, and the kidney invigorating essence, improve some abnormal smells from the patients mental, that Fructus Alpiniae Oxyphyllae is kept fit Gentle Chinese medicine, has certain anti-aging effects to human body, is a kind of health product improving immunity.The present invention is based on Fructus Mori Material, adds some nourishing the liver and kidney, strengthening the tendons and bones, invigorates blood circulation and mend the Chinese medicine that marrow, nature and flavor are gentle, and the present invention is obviously improved mouthfeel, for Chinese medicine odor is poor, and mouthfeel is the best, in-convenience in use, make the biggest improvement, there is the strongest market prospect；All medicines share benefit Lung gold, kidney nourishing water, gas of astringing the lung, cough-relieving are breathed heavily, and the kidney invigorating is smart, it is mental to improve, therefore can Fructus Alpiniae Oxyphyllae keep fit, and has certain defying age to make to human body With, it is a kind of health product improving immunity.

Claims

1. the preparation method of the Fructus Mori oral liquid improving immunity, it is characterised in that comprise the following steps:

A. the extraction of Fructus Mori, as component 1；

C. by 2-in-1 also to above two extracting solution component 1 and component, add Mel after concentration or dextrin is in harmonious proportion, prepare after disinfection Become oral solutions.

Improve the preparation method of the Fructus Mori oral liquid of immunity the most according to claim 1, it is characterised in that described step a In, gather during annual 4-6 month Fructus Mori fruit maturation, clean, decontamination, dry after drying or slightly steaming.

Improve the preparation method of the Fructus Mori oral liquid of immunity the most according to claim 1, it is characterised in that described step a In, farther including, Fructus Mori good for dry in the sun are soaked and has been placed in lid stainless steel cask, add 70% ethanol, quality is coarse granule 0.8-1 times, stir, moistening airtight placement more than 1 hour, make fully to expand；By filter plate gauze bag bottom percolator Drug sample after moistening expansion is mixed pine and is done to dissipate by parcel again after paving, then contain powder with rustless steel spoon, load percolation uniformly Cylinder, fills 10-12 cm thick, even by T-bar pressure, then presses aforesaid operations, and loading in layer is suitably pressurizeed, and medicated powder loads not 2/3 eminence of percolator must be exceeded；Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts one Container, is then slowly added into 70% ethanol；Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close Close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, control percolation speed and be generally 1000g medical material Outflow 2～3ml per minute, filtrate is put into liquid container, and is poured ethanol during emptying into liquid container；Percolate is merged quiet Put, stand for standby use, as component 1.

Improve the preparation method of the Fructus Mori oral liquid of immunity the most according to claim 1, it is characterised in that described step b In, the medicine of remaining crude drug is put in ethanol, soaks 1-2 days, then heating extraction 2 times, each 1-2 hour, 2 times are extracted Liquid merges standing；The medicinal residues of the raw medicinal material crossed by above-mentioned ethanol extraction again add water heating and refluxing extraction 2 times, and each 1～2 is little Time, 2 extracting solution are merged and stands；Above two extracting solution is merged, the filter of 1.35 when concentrating under reduced pressure relative density is 80 DEG C Liquid, reclaims ethanol, and by gained filtrate adjustment proportion to 1.38, reduce pressure to obtain extractum, becomes component 2.

Improve the preparation method of the Fructus Mori oral liquid of immunity the most according to claim 1, it is characterised in that described step c In, by 2-in-1 to component 1 and component and after, insert in economic benefits and social benefits vacuum concentrator, first concentrating the filtrate to relative density when 80 DEG C is The concentrated solution of 1.38, sets to 0～5 DEG C of deepfreezes 24 hours；The filter aid kieselguhr adding 0.3% by cold preservation liquid, filters, and filtrate is again Insert in economic benefits and social benefits vacuum concentrator, be concentrated into every 1ml extractum Han 0.1g, add dextrin and be in harmonious proportion, after disinfection, be prepared as oral liquid.

6. the preparation method of the Fructus Mori oral liquid improving immunity, it is characterised in that comprise the following steps:

A. the preparation of Fructus Mori, as component 1；

B. remaining crude drug described chopping is extracted as component 2；

Improve the preparation method of the Fructus Mori oral liquid of immunity the most according to claim 6, it is characterised in that described step a In, the Fructus Mori that dry in the sun is good are steeped in ethanol after 1-2 days, heating extraction 2 times, each 1-2 hour, take supernatant, united extraction Liquid, 100-110 mesh filters, then the ultrafiltration post ultrafiltration that molecular weight is 6000-10000 through damming, and ultrafiltrate concentrating under reduced pressure is the closeest The extractum of 1.36 when degree is 80 DEG C, heating is concentrated into paste, stand for standby use, becomes component 1；In described step b, by remaining crude drug Material mixes, and shreds 100～120 mesh sieves, and after sieving, fine powder is standby, and coarse granule puts into acid and alkali-resistance infusion kettle, at room temperature, with 70 Ethanol more than spending impregnates 3～7 days together, then heating and refluxing extraction 2 times, each 1～2 hour, merges quiet by 2 extracting solution Put, filter, after separation, take filtrate；By filtered through gauze, adding 50-60% ethanol in residue, 60 DEG C-70 DEG C are continued extraction 2h, often 10min stirs once, filtered through gauze, merges lixiviating solution, and being condensed into pasty state becomes component 2；In described step c, by component 1 and group Point 2-in-1 and after, insert in economic benefits and social benefits vacuum concentrator, when being concentrated into 80 DEG C, relative density is the extractum of 1.60, the unguentum after concentration Add Mel or dextrin is in harmonious proportion, bottle after ultraviolet ray sterilization bactericidal.

8. the Fructus Mori oral liquid improving immunity, it is characterised in that include the crude drug of following weight portion: Fructus Mori 10～50 Part, Rhizoma Curculiginis 10～20 parts, Radix Rehmanniae Preparata 10～20 parts, Fructus Schisandrae Chinensis 10～20 parts, Herba Taraxaci 10～20 parts, Poria 10～20 parts, ground bone Skin 10～20 parts, Cortex Acanthopancis 10～20 parts, Radix Polygoni Multiflori Preparata 10～20 parts, Fructus Corni 10～20 parts, Herba Taxilli 10～20 parts, Herb Gynostemmae Pentaphylli 10～20 parts, the Radix Astragali 10～20 parts, Herba Sedi 10～20 parts, Radix Codonopsis 10～20 parts, Fructus Ligustri Lucidi 10～20 parts, Semen Cuscutae 10～20 Part, Cortex Moutan 10～20 parts, Fructus Gardeniae 10～20 parts.

Improve the Fructus Mori oral liquid of immunity the most according to claim 1, it is characterised in that described Fructus Mori oral liquid also includes The crude drug of following weight portion: Fructus Mori 10～40 parts, Rhizoma Curculiginis 10～15 parts, Radix Rehmanniae Preparata 10～15 parts, Fructus Schisandrae Chinensis 10～15 parts, Pu Gong English 10～15 parts, Poria 10～15 parts, Cortex Lycii 10～15 parts, Cortex Acanthopancis 10～15 parts, Radix Polygoni Multiflori Preparata 10～15 parts, Fructus Corni 10 ～15 parts, Herba Taxilli 10～15 parts, Herb Gynostemmae Pentaphylli 10～20 parts, the Radix Astragali 10～20 parts, Herba Sedi 10～20 parts, Radix Codonopsis 10～20 Part, Fructus Ligustri Lucidi 10～20 parts, Semen Cuscutae 10～20 parts, Cortex Moutan 10～20 parts, Fructus Gardeniae 10～20 parts.

Improve the Fructus Mori oral liquid of immunity the most according to claim 1, it is characterised in that described Fructus Mori oral liquid also wraps Include the crude drug of following weight portion: Fructus Mori 10～30 parts, Rhizoma Curculiginis 10～20 parts, Radix Rehmanniae Preparata 10～20 parts, Fructus Schisandrae Chinensis 10～20 parts, Pu Herba Taraxaci 10～20 parts, Poria 10～20 parts, Cortex Lycii 10～20 parts, Cortex Acanthopancis 10～20 parts, Radix Polygoni Multiflori Preparata 10～20 parts, Fructus Corni 10～20 parts, Herba Taxilli 10～20 parts, Herb Gynostemmae Pentaphylli 10～15 parts, the Radix Astragali 10～15 parts, Herba Sedi 10～15 parts, Radix Codonopsis 10～15 Part, Fructus Ligustri Lucidi 10～15 parts, Semen Cuscutae 10～15 parts, Cortex Moutan 10～15 parts, Fructus Gardeniae 10～15 parts.