CN108066707A - Reduce Chinese medicine composition, its preparation method and the application of blood glucose - Google Patents
Reduce Chinese medicine composition, its preparation method and the application of blood glucose Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
Abstract
The present invention relates to the field of Chinese medicines, and more particularly to a kind of Chinese medicine composition, its preparation method and application for reducing blood glucose.The Chinese medicine composition for reducing blood glucose is made of plurality of raw materials, and in parts by weight, plurality of raw materials includes：Plurality of raw materials includes：15 30 parts of 9 15 parts of Poria cocos, 9 12 parts of umbellate pore furgus, 9 15 parts of rhizoma alismatis, 69 parts of cassia twig, 15 30 parts of the fruit of glossy privet, 15 20 parts of eclipta, raw 30 60 parts of Radix Astragali, 9 15 parts of Radix Codonopsis, raw 9 12 parts of Rhizoma Atractylodis Macrocephalae, 9 15 parts of Radix Angelicae Sinensis, 9 12 parts of turmeric and Rhizoma Dioscoreae.The Chinese medicine composition be based on " spleen deficiency lose fortune; it is wet it is turbid in stop " Pathogenesis of Diabetes, it sets forth one's views from invigorating the spleen for eliminating dampness, using umbellate pore furgus, rhizoma alismatis, Rhizoma Atractylodis Macrocephalae, Poria cocos, cassia twig to be substantially square, take into account the deficiency of both qi and yin interpretation of the cause, onset and process of an illness quenched one's thirst, can effectively can to wash away diabetes wet turbid basic for supplementing qi and nourishing yin, invigorating the spleen for eliminating dampness, play significant blood sugar reducing function.
Description
Technical field
The present invention relates to the field of Chinese medicines, and more particularly to it is a kind of reduce the Chinese medicine composition of blood glucose, its preparation method and
Using.
Background technology
Diabetes are comprehensive using carbohydrate metabolism disturbance as the clinic of clinical manifestation by common caused one group of h and E factor
Close disease.It by insulin deficit alone or in combination insulin action obstacle so as to cause three big substances and water and electrolyte etc.
Metabolic disorder.Clinically using chronic hyperglycemia as main feature, to eat, mostly drink, diuresis, weight loss etc. are Major Clinical table more
It is existing.The traditional Chinese medical science also plays important, unique, irreplaceable role in the field for the treatment of diabetes.Diabetes are in the traditional Chinese medical science
" quenching one's thirst " scope should be belonged to, it is that more drinks, more food, diuresis, bodies are gradually become thin a kind of weak disease to prompt it.Modern age, doctor opened tin
Pure proposition, " the so-called diabetes of i.e. doctor trained in Western medicine of quenching one's thirst ", it is believed that this disease " arise from middle burnt and pole in up and down ", and set forth one's views from " spleen ", it proposes
" dysfunction of the spleen in transport, trough body fluid metabolic disorder " is diabete main pathogenesis, and " dysfunction of the spleen in transport, phlegm stagnation in collateral " is that diabete triggers entirely
Body complication main pathogenesis, establish beneficial temper, support spleen is cloudy, dry spleen is wet, let out the spleen-heat syndrome, wet spleen sun, smooth temper, " the fortune of logical spleen network
Spleen " is treated.
TCM treatment of diabetes is based on the interpretation of the cause, onset and process of an illness of " deficiency of Yin is this, scorching for mark ", the clinical more enriching yin lifes of prescription medicine at present
Tianjin is mostly added and subtracted with side with " Liuwei Dihuang Wan ".But the traditional Chinese and western medicine interpretation of the cause, onset and process of an illness that analysis of diabetes is formed, traditional Chinese medicine think that dirty lose is good for
Fortune, trough body fluid metabolic disorder is diabete main pathogenesis, for the position, form with reference to the spleen of literature research description, the traditional Chinese medical science
Spleen in the theory of visceral outward manifestation contains spleen and pancreas in modern anatomy, but the physiological function of spleen is beyond spleen and pancreas in modern medicine
Gland function.The function of spleen includes main transporting, and main liter is clear, and main system blood, wherein transporting and transforming nutrients from foodstuff and transformation of body flaud are the major functions of spleen,
" fortune " i.e. transhipment conveying, " change " is digested and assimilated, and the duty of transporting and transforming nutrients from foodstuff is that ingesta is converted into cereal nutrient, and is transferred complete
The process of body.Spleen is distributed in lung by the aqueous of absorption is defeated upwards, drops spreading whole body by a surname of lung or turns to sweat discharge, downwards will generation
It thanks that extra aqueous is defeated to be distributed in kidney, urine discharge is formed through gasification all.It can be seen that the transportation capabilities of spleen cover diet battalion
That supports substance digests and assimilates and is metabolized overall process, and " spleen must be transported, and be good for ", fortune is the basic physiological function of spleen, there is fortune then having, fortune
Its is precise and tiny, changes its trough, the precise and tiny compress whole body of transporting and transforming nutrients from foodstuff.It can be seen that critical role of the spleen for human body.Due to the transporting work(of spleen
Imbalance and disturbance state during upper and lower burnt lung, the defeated cloth of kidney trough body fluid and utilization caused by neglecting one's duty cause to quench one's thirst as disease；
The dysfunction of the spleen in transport is with the passing of time, then easily raw turbid simultaneously, and the deficiency of vital energy cannot take the photograph blood, phlegm stagnation train of thought, body fluid and exhaust the originals such as then channels is puckery in addition
Also easily there are the pathological products such as obstruction of collaterals by blood stasis long, ultimately result in phlegm and blood stasis in cause, disease.It is therefore contemplated that " invigorating the spleen for eliminating dampness " treatment is
The basic therapy of diabetes, and through the overall process for the treatment of diabetes.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for reducing blood glucose, which is based on " spleen deficiency mistake
Fortune, it is wet it is turbid in stop " Pathogenesis of Diabetes, from invigorating the spleen for eliminating dampness set forth one's views, using umbellate pore furgus, rhizoma alismatis, Rhizoma Atractylodis Macrocephalae, Poria cocos, cassia twig for substantially just, take into account
The deficiency of both qi and yin interpretation of the cause, onset and process of an illness quenched one's thirst, can effectively can to wash away diabetes wet turbid basic for supplementing qi and nourishing yin, invigorating the spleen for eliminating dampness, play notable
Blood sugar reducing function.
Another object of the present invention is to provide a kind of preparation method for the Chinese medicine composition for reducing blood glucose, this method operation
Step is simple, and operating condition is mild and is easily achieved.
Another object of the present invention is to provide a kind of Chinese medicine composition for reducing blood glucose to prepare treatment diabetes medicament
In application, provide a kind of new Chinese medicine composition for the treatment of diabetes.
The present invention is solved its technical problem and is realized using following technical scheme：
The present invention proposes a kind of Chinese medicine composition for reducing blood glucose, reduces the Chinese medicine composition of blood glucose by plurality of raw materials system
Into in parts by weight, plurality of raw materials includes：Plurality of raw materials includes：9-15 parts of Poria cocos, 9-12 parts of umbellate pore furgus, 9-15 parts of rhizoma alismatis, cassia twig
6-9 parts, 15-30 parts of the fruit of glossy privet, 15-20 parts of eclipta, raw 30-60 part of Radix Astragali, 9-15 parts of Radix Codonopsis, give birth to 9-12 parts of Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis
15-30 parts of 9-15 parts, 9-12 parts of turmeric and Rhizoma Dioscoreae.
The present invention proposes a kind of method for the Chinese medicine composition for preparing and reducing blood glucose, comprises the following steps：In parts by weight,
By 9-15 parts of Poria cocos, 9-12 parts of umbellate pore furgus, 9-15 parts of rhizoma alismatis, 6-9 parts of cassia twig, 15-30 parts of the fruit of glossy privet, 15-20 parts of eclipta, raw Huang
After 15-30 parts of 30-60 parts of stilbene, 9-15 parts of Radix Codonopsis, raw 9-12 parts of Rhizoma Atractylodis Macrocephalae, 9-15 parts of Radix Angelicae Sinensis, 9-12 parts of turmeric and Rhizoma Dioscoreae mixing
Carry out diacolation.
The present invention proposes that a kind of Chinese medicine composition for reducing blood glucose is preparing the application in treating diabetes medicament.
The advantageous effect of the Chinese medicine composition of the reduction blood glucose of the embodiment of the present invention is：The Chinese medicine composition of the present invention utilizes
Poria cocos, umbellate pore furgus give birth to the drug of four taste converge to the spleen channel of Radix Astragali and Radix Codonopsis as main ingredient, with rhizoma alismatis, cassia twig, raw Rhizoma Atractylodis Macrocephalae and ought be classified as ministerial drug,
Assistant with turmeric, the fruit of glossy privet and eclipta can beneficial temper, support spleen is cloudy, dry spleen is wet, let out the spleen-heat syndrome, wet spleen sun, smooth temper, logical spleen network,
Then it is wet turbid basic can to wash away diabetes for supplementing qi and nourishing yin, invigorating the spleen for eliminating dampness, then realizes the reduction of blood glucose.
Specific embodiment
It, below will be in the embodiment of the present invention to make the purpose, technical scheme and advantage of the embodiment of the present invention clearer
Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, builds according to normal condition or manufacturer
The condition of view carries out.Reagents or instruments used without specified manufacturer is the conventional production that can be obtained by commercially available purchase
Product.
In the description of the present invention, it is necessary to which explanation, term " first ", " second " etc. are only used for distinguishing description, without
It is understood that indicate or imply relative importance.
Chinese medicine composition, its preparation method and the application of the reduction blood glucose of the embodiment of the present invention are carried out specifically below
It is bright.
A kind of Chinese medicine composition for reducing blood glucose, is made, in parts by weight, plurality of raw materials includes of plurality of raw materials：Fu
9-15 parts of Siberian cocklebur, 9-12 parts of umbellate pore furgus, 9-15 parts of rhizoma alismatis, 6-9 parts of cassia twig, 15-30 parts of the fruit of glossy privet, 15-20 parts of eclipta, raw Radix Astragali
15-30 parts of 30-60 parts, 9-15 parts of Radix Codonopsis, raw 9-12 parts of Rhizoma Atractylodis Macrocephalae, 9-15 parts of Radix Angelicae Sinensis, 9-12 parts of turmeric and Rhizoma Dioscoreae.It is it is preferred that more
Kind raw material includes 10-14 parts of Poria cocos, 10-11 parts of umbellate pore furgus, 10-14 parts of rhizoma alismatis, 7-8 parts of cassia twig, 17-25 parts of the fruit of glossy privet, eclipta
17-18 parts, raw 35-55 parts of Radix Astragali, 10-13 parts of Radix Codonopsis, raw 10-11 parts of Rhizoma Atractylodis Macrocephalae, 10-14 parts of Radix Angelicae Sinensis, 10-11 parts of turmeric and raw mountain
17-25 parts of medicine.It is further preferred that plurality of raw materials includes 11-12 parts of Poria cocos, 10-11 parts of umbellate pore furgus, 12-13 parts of rhizoma alismatis, 7-8 parts of cassia twig, female
Loyal sub- 20-22 part, 17-18 part of eclipta, give birth to 40-45 parts of Radix Astragali, 11-12 parts of Radix Codonopsis, give birth to 10-11 parts of Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis 11-13
18-20 parts of part, 10-11 parts of turmeric and Rhizoma Dioscoreae
There are good therapeutic effect, specifically, the embodiment of the present invention to hypoglycemic by acting synergistically between above-mentioned raw materials
Drug with Poria cocos, umbellate pore furgus, four taste converge to the spleen channel of raw Radix Astragali and Radix Codonopsis can promote the discharge of moisture in spleen, help spleen for main ingredient
Gas so that yin and yang 2 Qi balances in spleen, realizes smooth temper, logical spleen network, then realizes the effect for the treatment of so that physical efficiency water, nutrition
Metabolic balance.Meanwhile with rhizoma alismatis, cassia twig, raw Rhizoma Atractylodis Macrocephalae and when be classified as ministerial drug can further invigoration spleen qi, support that spleen is cloudy, wet spleen
Sun promotes splenic function reparation and perfect.Finally help the blood that can further promote the internal stasis of blood stagnant with turmeric, the fruit of glossy privet and eclipta
Liquid stream is moved so that above-mentioned each drug, which mutually acts synergistically, promotes the function of spleen, then reduces blood glucose.
Specifically, Poria cocos is the dry sclerotia of On Polyporaceae Poria cocos Poria cocos (Schw.) Wolf.Sweet in flavor,
Light, mild-natured, the thoughts of returning home, lung, spleen, kidney channel have the effect of clearing damp and promoting diuresis, invigorating the spleen, calming heart.Poria cocos is energy in embodiments of the present invention
Enough promote transport of the spleen to water, promote digestion of the human body to water, food, avoid congestion blood block, prevent foul smell from being generated in human body, after
And reduce blood glucose.
Umbellate pore furgus is the dry sclerotia of On Polyporaceae umbellate pore furgus Polyporus umbellatus (Pers.) Fries, taste
It is sweet, light, it puts down.The thoughts of returning home, spleen, stomach, lung, kidney channel.There is clearing damp and promoting diuresis, the effect of umbellate pore furgus in embodiments of the present invention is energy
Enough promote the function of transporting and transforming nutrients from foodstuff and transformation of body flaud in spleen, then promote digesting and assimilating and being metabolized for dietary nutrient, prevent
Because phlegm stagnation train of thought, body fluid caused by the functional disturbance of spleen exhaust the illnesss such as then channels is puckery.
Radix Astragali slightly warm in nature sweet in flavor, return lung, spleen, kidney, Liver Channel, Radix Astragali containing saponin, sucrose, polysaccharide, a variety of amino acid, folic acid and
The various trace elements such as selenium, zinc, copper.Have invigorating qi for strengthening superficies, profit water detumescence, enhancing body's immunity, liver protection, diuresis, anti-aging,
Resisting stress, decompression and wide antibacterial action.Radix Astragali is monarch drug in a prescription in embodiments of the present invention, plays main therapeutic effect,
Can profit water detumescence, promote metabolism, enhance immunity of organisms.
Radix Codonopsis is the dry root of Campanulaceae Radix Codonopsis, codonopsis pilosula var. modesta or radix codonpsis tangshen etc., and Radix Codonopsis is sweet in flavor, mild-natured.Returns spleen,
Lung channel.There is tonifying middle-Jiao and Qi, quench the thirst, strengthening spleen and tonifying lung, the effect of nourishes blood and promotes the production of body fluid.Being the effect of Radix Codonopsis in embodiments of the present invention can
Invigoration spleen qi, supports spleen the moon, then promotes splenic function perfect.
Rhizoma alismatis is the dry tuber of Notes On Alism At Aceae rhizoma alismatis Alisma orientalis (Sam.) Juzep..Its is sweet in flavor,
It is light, it is cold in nature.Return kidney, bladder warp.With clearing damp and promoting diuresis, the effect of expelling the heat-evil, change turbid lipid-loweringing, in embodiments of the present invention, rhizoma alismatis
Effect is to aid in Poria cocos, umbellate pore furgus, four taste monarch drug in a prescription of raw Radix Astragali and Radix Codonopsis, promotes the excretion of moisture in spleen, is let out except the spleen-heat syndrome, then sharp
Recover its function in spleen.
Cassia twig, it is acrid flavour, sweet, it is warm-natured.Return lung, the heart, bladder warp.With inducing sweat and dispelling exogenous evils, eliminating cold to stop pain, activating YANG and prormoting functioning of QI work(
Effect.Cassia twig can promote the evaporation of skin epidermis moisture in embodiments of the present invention, further speed up the wet row of the water gathered in vivo
It puts, while promotes the yang-energy of spleen, promote its gas resilience to dirt so that human body's Qi reaches equilibrium between yin and yang.
Raw Rhizoma Atractylodis Macrocephalae is the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae.Returns spleen, stomach, it is bitter, sweet and warm-natured, there is dehumidifying benefit
The effect of dry and middle QI invigorating, middle benefit gas, the moisture of spleen can be removed by giving birth to Rhizoma Atractylodis Macrocephalae in embodiments of the present invention, and supplement spleen is because stasis
Moisture caused by YANG QI deficiency, then realize spleen in Yinyang balance.
When the dry root for being classified as umbelliferae angelica Angelica sinensis (Oliv.) Diels.It is sweet in flavor, pungent, property
Temperature.Return liver, the heart, the spleen channel.With replenishing and activating blood, menstruction regulating and pain relieving, the effect of relaxing bowel.Radix Angelicae Sinensis is in the present invention is embodiment
Effect is to play the role of help, can promote the balance of human body vim and vigour, promotes the recovery of splenic function.
Turmeric is the dry rhizome of zingiberaceous plant turmeric Curcuma longa L..Its acrid flavour, hardship, it is warm-natured.Returns spleen, liver
Through.With blood-breaking, the effect of relieving pain of dysmenorrhea.Then can to abolish the stasis of blood stagnant for turmeric in embodiments of the present invention, promotes internal
The flowing of gas so that temper flowing is more smooth, mitigates the turbid injury to spleen of becoming silted up.
The fruit of glossy privet, for the dry mature fruit of Oleaceae plants glossy privet Ligustrum lucidum Ait., sweet, bitter, cold.
Return liver and kidney channel, have and tonify the liver and kidney, the effect of improving eyesight, clearind deficient heat, the fruit of glossy privet can promote help spleen in embodiments of the present invention
Gas removes the spleen-heat syndrome, then promotes spleen network clear and coherent.
Eclipta also known as Eclipta prostrata, acid sweet in flavor is cool in nature, enters liver kidney two warp, nontoxic.All herbal medicine has cool blood, stops blooding, disappears
The effect of swollen, strong.Blood flow is can speed up in the embodiment of the present invention eclipta, promotes the discharge of internal extravasated blood, then
It can realize invigorating the spleen for eliminating dampness.
The embodiment of the present invention also provides a kind of preparation method for the Chinese medicine composition for reducing blood glucose, comprises the following steps：
By 9-15 parts of Poria cocos, 9-12 parts of umbellate pore furgus, 9-15 parts of rhizoma alismatis, 6-9 parts of cassia twig, 15-30 parts of the fruit of glossy privet, eclipta 15-
20 parts, raw 30-60 parts of Radix Astragali, 9-15 parts of Radix Codonopsis, raw 9-12 parts of Rhizoma Atractylodis Macrocephalae, 9-15 parts of Radix Angelicae Sinensis, 9-12 parts of turmeric and Rhizoma Dioscoreae 15-30
It is crushed after part mixing so that above-mentioned each drug then contacts with raw material convenient for solvent into coarse powder or thin block, realizes and live
The extraction of property ingredient.
Either can above-mentioned each bulk pharmaceutical chemicals individually first be ground into coarse powder or thin block then to extract again.Coarse powder or
The thin block of person refers to that above-mentioned each raw material has larger surface area and small volume, but not is driven with the flowing of liquid
Flowing.
Then said mixture is impregnated in water 30-60 minutes so that above-mentioned each raw material expansion is then prevented rear
During continuous diacolation, above-mentioned each raw material reabsorbs solvent expansion, reduces the gap between each raw material, is unfavorable for solvent
Flowing.
Seepage pressure effects are then carried out, i.e., above-mentioned each raw material are positioned in percolating device, and in air-discharging percolating device
Air between each raw material ensures that solvent can come into full contact with each raw material, then ensures extraction effect.
Then extracted successively using the alcoholic solvent of the alcoholic solvent of 30-40%, the alcoholic solvent of 60-70% and 90-97%,
It is passed through above-mentioned solvent successively i.e. into percolating device to extract, the solvent quality concentration being passed through successively increases, and ensures each original
Active ingredient in material can be fully extracted out.
Further, above-mentioned alcoholic solvent is monoalcohol solvent, is preferably ethyl alcohol.
Further, carry out diacolation three times using above-mentioned solvent, when each diacolation need to impregnate 1-3 it is small when.I.e. solvent exists
Contacted with each bulk pharmaceutical chemicals in percolating device 1-3 it is small when, the then extraction effect of guarantee diacolation.
With rate collection maceration extract 1-3 milliliters per minute after dipping.The flow velocity for collecting maceration extract, that is, percolate was not easy
Soon, prevent from generating bubble between raw material, meanwhile, the active ingredient in extracting solution is prevented to be trapped in percolating device.
The Chinese medicine composition for reducing blood glucose can also be pressed above-mentioned each raw material with water by decocting to obtain, particularly
It is 1 according to mass ratio:It is infiltrated 20-30 minutes after the ratio mixing of 8-10, is then boiled using intense fire (big fire), then use slow boiling
(small fire) keeps fluidized state, and persistently decocts, until soup for original water a quarter to 1/3rd, filtering.
The water that the dregs of a decoction obtained after filtering rejoin 3-6 times decocted using slow boiling (small fire), until soup is therefore
1/3rd or a quarter amount of secondary water.Mix the soup decocted twice.
Chinese medicine composition on the reduction blood glucose is taken, and in early, once a dose by 30min before the meal, before dinner.14d is 1
The course for the treatment of.
The embodiment of the present invention also provides a kind of Chinese medicine composition for reducing blood glucose answering in treatment diabetes medicament is prepared
With.
A kind of Chinese medicine composition for reducing blood glucose provided by the invention is returned using Poria cocos, umbellate pore furgus, raw Radix Astragali and four taste of Radix Codonopsis
The drug of the spleen channel is main ingredient, with rhizoma alismatis, cassia twig, gives birth to Rhizoma Atractylodis Macrocephalae and when being classified as ministerial drug, and helping being capable of benefit with turmeric, the fruit of glossy privet and eclipta
Temper, support spleen is cloudy, dry spleen is wet, let out the spleen-heat syndrome, wet spleen sun, smooth temper, logical spleen network, then supplementing qi and nourishing yin, invigorating the spleen for eliminating dampness can wash away
Diabetes are wet turbid basic, then realize the reduction of blood glucose.
The feature and performance of the present invention are described in further detail with reference to embodiments.
Embodiment 1
The present embodiment provides a kind of Chinese medicine compositions for reducing blood glucose, are mainly made of plurality of raw materials.Plurality of raw materials bag
Include 9 parts of Poria cocos, 9 parts of umbellate pore furgus, 9 parts of rhizoma alismatis, 6 parts of cassia twig, 15 parts of the fruit of glossy privet, 15 parts of eclipta, raw 30 parts of Radix Astragali, 9 parts of Radix Codonopsis, life
15 parts of 9 parts of Rhizoma Atractylodis Macrocephalae, 9 parts of Radix Angelicae Sinensis, 9 parts of turmeric and Rhizoma Dioscoreae.
The method for preparing the Chinese medicine composition of the reduction blood glucose is as follows：
By Poria cocos, umbellate pore furgus, rhizoma alismatis, cassia twig, the fruit of glossy privet, eclipta, raw Radix Astragali, Radix Codonopsis, raw Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, turmeric and life
It is thin block to be crushed after Chinese yam mixing, is then positioned in water and impregnates 30 minutes.
Above-mentioned each raw material is positioned in percolating device, and the air in air-discharging percolating device between each raw material, after
It is extracted successively using 30% ethyl alcohol, 60% ethyl alcohol and 90% ethyl alcohol, when each diacolation, needs dipping 1 small, leaching
With 1 milliliter per minute of rate collection maceration extract after stain.
The present embodiment provides a kind of Chinese medicine compositions for reducing blood glucose to prepare the application in treating diabetes medicament.
Embodiment 2
The present embodiment provides a kind of Chinese medicine compositions for reducing blood glucose, are mainly made of plurality of raw materials.Plurality of raw materials bag
Include 15 parts of Poria cocos, 12 parts of umbellate pore furgus, 15 parts of rhizoma alismatis, 9 parts of cassia twig, 30 parts of the fruit of glossy privet, 20 parts of eclipta, raw 60 parts of Radix Astragali, Radix Codonopsis 15
20 parts of part, raw 12 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of Radix Angelicae Sinensis, 12 parts of turmeric and Rhizoma Dioscoreae.
The method for preparing the Chinese medicine composition of the reduction blood glucose is as follows：
By Poria cocos, umbellate pore furgus, rhizoma alismatis, cassia twig, the fruit of glossy privet, eclipta, raw Radix Astragali, Radix Codonopsis, raw Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, turmeric and life
It is thin block to be crushed after Chinese yam mixing, is then positioned in water and impregnates 60 minutes.
Above-mentioned each raw material is positioned in percolating device, and the air in air-discharging percolating device between each raw material, after
It is extracted successively using 40% ethyl alcohol, 70% ethyl alcohol and 97% ethyl alcohol, when each diacolation, needs dipping 3 small, leaching
With 3 milliliters per minute of rate collection maceration extract after stain.
Embodiment 3
The present embodiment provides a kind of Chinese medicine compositions for reducing blood glucose, are mainly made of plurality of raw materials.Plurality of raw materials bag
Include 10 parts of Poria cocos, 11 parts of umbellate pore furgus, 14 parts of rhizoma alismatis, 8 parts of cassia twig, 25 parts of the fruit of glossy privet, 17 parts of eclipta, raw 35 parts of Radix Astragali, Radix Codonopsis 10
17 parts of part, raw 10 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Radix Angelicae Sinensis, 10 parts of turmeric and Rhizoma Dioscoreae.
The method for preparing the Chinese medicine composition of the reduction blood glucose is as follows：
By Poria cocos, umbellate pore furgus, rhizoma alismatis, cassia twig, the fruit of glossy privet, eclipta, raw Radix Astragali, Radix Codonopsis, raw Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, turmeric and life
It is thin block to be crushed after Chinese yam mixing, is then positioned in water and impregnates 45 minutes.
Above-mentioned each raw material is positioned in percolating device, and the air in air-discharging percolating device between each raw material, after
It is extracted successively using 32% ethyl alcohol, 65% ethyl alcohol and 95% ethyl alcohol, when each diacolation, needs dipping 2 small, leaching
With 2 milliliters per minute of rate collection maceration extract after stain.
Embodiment 4
The present embodiment provides a kind of Chinese medicine compositions for reducing blood glucose, are mainly made of plurality of raw materials.Plurality of raw materials bag
Include 14 parts of Poria cocos, 10 parts of umbellate pore furgus, 10 parts of rhizoma alismatis, 7 parts of cassia twig, 17 parts of the fruit of glossy privet, 18 parts of eclipta, raw 55 parts of Radix Astragali, Radix Codonopsis 13
25 parts of part, raw 11 parts of Rhizoma Atractylodis Macrocephalae, 14 parts of Radix Angelicae Sinensis, 11 parts of turmeric and Rhizoma Dioscoreae.
The method for preparing the Chinese medicine composition of the reduction blood glucose is as follows：
By Poria cocos, umbellate pore furgus, rhizoma alismatis, cassia twig, the fruit of glossy privet, eclipta, raw Radix Astragali, Radix Codonopsis, raw Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, turmeric and life
It is thin block to be crushed after Chinese yam mixing, is then positioned in water and impregnates 40 minutes.
Above-mentioned each raw material is positioned in percolating device, and the air in air-discharging percolating device between each raw material, after
It is extracted successively using 35% ethyl alcohol, 67% ethyl alcohol and 91% ethyl alcohol, when each diacolation, needs dipping 1.5 small,
With 2 milliliters per minute of rate collection maceration extract after dipping.
Embodiment 5
The present embodiment provides a kind of Chinese medicine compositions for reducing blood glucose, are mainly made of plurality of raw materials.Plurality of raw materials bag
Include 12 parts of Poria cocos, 11 parts of umbellate pore furgus, 13 parts of rhizoma alismatis, 7 parts of cassia twig, 20 parts of the fruit of glossy privet, 17 parts of eclipta, raw 40 parts of Radix Astragali, Radix Codonopsis 11
18 parts of part, raw 10 parts of Rhizoma Atractylodis Macrocephalae, 11 parts of Radix Angelicae Sinensis, 10 parts of turmeric and Rhizoma Dioscoreae.
The method for preparing the Chinese medicine composition of the reduction blood glucose is as follows：
By Poria cocos, umbellate pore furgus, rhizoma alismatis, cassia twig, the fruit of glossy privet, eclipta, raw Radix Astragali, Radix Codonopsis, raw Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, turmeric and life
Chinese yam mixing after with water according to mass ratio be 1:It infiltrates 20 minutes after 8 ratio mixing, is then boiled using intense fire (big fire), and
Fluidized state is kept with slow boiling (small fire) afterwards, and is persistently decocted, until soup is a quarter of original water, filtering.
The water that the dregs of a decoction obtained after filtering rejoin 3 times decocted using slow boiling (small fire), until soup is this
/ 3rd amounts of water.Mix the soup decocted twice.
Embodiment 6
The present embodiment provides a kind of Chinese medicine compositions for reducing blood glucose, are mainly made of plurality of raw materials.Plurality of raw materials bag
Include 11 parts of Poria cocos, 10 parts of umbellate pore furgus, 12 parts of rhizoma alismatis, 8 parts of cassia twig, 22 parts of the fruit of glossy privet, 18 parts of eclipta, raw 45 parts of Radix Astragali, Radix Codonopsis 12
20 parts of part, raw 11 parts of Rhizoma Atractylodis Macrocephalae, 13 parts of Radix Angelicae Sinensis, 11 parts of turmeric and Rhizoma Dioscoreae.
The method for preparing the Chinese medicine composition of the reduction blood glucose is as follows：
By Poria cocos, umbellate pore furgus, rhizoma alismatis, cassia twig, the fruit of glossy privet, eclipta, raw Radix Astragali, Radix Codonopsis, raw Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, turmeric and life
Chinese yam mixing after with water according to mass ratio be 1:It infiltrates 30 minutes after 10 ratio mixing, is then boiled using intense fire (big fire),
Fluidized state then is kept with slow boiling (small fire), and is persistently decocted, until soup is 1/3rd of original water, filtering.
The water that the dregs of a decoction obtained after filtering rejoin 6 times decocted using slow boiling (small fire), until soup is this
The a quarter amount of water.Mix the soup decocted twice.
Experimental example
This experimental example is analyzed using statistics relevant knowledge, statistical procedures：The processing of 11.0 statistical softwares of SPSS.
Baseline Data case mix ratio chi-square criterion；Measurement data is represented with ± s；Different groups compare to be examined with t, same group treatment
Front and rear comparison paired t-test；Significance level takes α=0.05.
116 diabetes B patients are randomly divided into base set (n=38), Chinese medicine group (n=40) and Western medicine group (n=
38).Base set moves therapeutic intervention, the traditional Chinese medicine composition for treating that Chinese medicine group is provided with the embodiment of the present invention 1, Western medicine group with diet
It is treated with melbine enteric coatel tablets.Wherein, base set is health education+dietary therapy+suitable movement, and the Primary Care is to 2 types
The therapeutic effect of diabetes is affirmative, meets and generally acknowledges effectively, than principle.Western medicine group is to nurse one's health diet and suitable exercise as base
Plinth.Oral melbine hydrocloride enteric coatel tablets 0.5g, before daily breakfast, lunch and dinner half an hour take orally.Traditional Chinese medicinal components not in it is early before the meal, before dinner
Once a dose by 30min.14d is 1 course for the treatment of, evaluates curative effect after even served 2 courses for the treatment of, withdraws Chinese medicine 7d between two courses for the treatment of.
Select above-mentioned 116 patients include with exclusion criteria for：Patient age 18~75 years old (contain 18 years old, 75 years old) it
Between, deny using the drug for causing blood glucose rise before chemical examination, in the presence of the disease for causing secondary impaired sugar regulation, former treatment side
Case does not have before observation in 3 months in the case that adjustment maintains former therapeutic scheme constant, and different blood glucose levels reach good, empty
Abdomen glycemic control is in (7.00 ± 1.00) mmol/L, and in (10.00 ± 1.00) mmol/L, error amount is little for 2h-plasma glucose control
In 0.5%.2. exclusion criteria.Case inclusion criteria person is not met；Simple oral antidiabetic drug poor blood glucose control, use are exogenous
Injection of insulin person；Having Diabetic Acute complication in 3 months, (such as diabetic ketoacidosis, diabetes hyperosmolar nonketotic is hypertonic
Syndrome, lactic acidosis etc.) person；There are severe diabetes mellitus chronic complicating diseases (such as angina pectoris attacks, massive cerebral infarction, eye
Bottom bleeding, gangrene etc.) person；Merge various stress situations or the Liver and kidney function severely subnormal persons such as wound, infection；Merging tumour,
The severe primaries disease patient such as tuberculosis, hemopoietic system；There are history of operation or blood transfusion history person in 3 months；Gestation prepares gestation and feeds
Newborn phase women；Long-term Hormone class drug person；Mismatch person lost to follow-up before treatment, treatment end.
Therefore, the result that 116 patients are compared by statistics participates in Tables 1 and 2.
1 each group patient age of table and course of disease comparison sheet
2 each group case sex composition ratio of table and pretherapy and post-treatment changes of weight comparison sheet
Note：(n) patient's number of cases of research is not included.
By Tables 1 and 2, two groups of patient's weight are on a declining curve before relatively treating after being treated before two groups of treatments, but nothing
Significant significant difference (P=0.189).3 groups of patients are in age, the course of disease, sex composition, weight isobase data through statistics
Compare, no significant difference (P>0.05) it is, harmonious good, it is comparable.
Criterion of therapeutical effect：Reference《New Chinese medicine guideline of clinical investigations》Middle diabetes curative effect standard is drafted [8].It is effective:
Clinical symptoms, sign are obviously improved, and FBG and OGTT2PG drop to normal range (NR) or fall >=30%.Effectively:Clinical condition
Shape, sign take a favorable turn, and FBG and OGTT2PG drop to normal range (NR) or fall >=20%.It is invalid:Clinical symptoms, sign
It without improvement, or even aggravates, FBG and OGTT2PG drop to normal range (NR) or fall<20%.
Testing index：Blood glucose, insulin level measure.All patients in pretherapy and post-treatment blood sampling, measure fasting blood-glucose
(FBG), 2h-plasma glucose (2hBG), glycosylated hemoglobin (HbA1C) are detected using full-automatic biochemical detector, specific detection knot
Fruit is referring to table 3 and table 4.
3 each group patient of table pretherapy and post-treatment FBG and 2hBG change comparison sheet
Note：Compared with group before treatment, * P<0.05, * * P<0.01；Compared with after base set treatment, △ P<0.05, △ △ P<
0.01.Compared with after the treatment of Western medicine group, ▼ P<0.05, ▼ ▼ P<0.01.
By table 3, compare patient's fasting blood glucose level, Western medicine group and Chinese medicine group reduce apparent before relatively treating；With base
Plinth group compares, and the blood glucose level of Chinese medicine group and Western medicine group significantly reduces；Compared with Western medicine group, Chinese medicine group patient's fasting blood-glucose has
Reduction trend, but without significant significant difference.
By table 3, compare patient's 2h-plasma glucose level, drop before base set, Western medicine group and Chinese medicine group are relatively treated
It is low apparent；Compared with base set, Chinese medicine group and the horizontal reduction of Western medicine group 2h-plasma glucose；Compared with Western medicine group, Chinese medicine group patient
2h-plasma glucose is horizontal to be reduced significantly.
The horizontal variation comparison sheets of the pretherapy and post-treatment HbA1C of 4 each group patient of table
By table 4, compare patient's glycated hemoglobin levels, base set and western medicine component before its treatment compared with not having drop
Low tendency, but without significant significant difference；Level significantly reduces before relatively being treated after Chinese medicine group patient treatment；After the treatment of Chinese medicine group
The glycated hemoglobin levels of patient are significantly reduced compared with base set and Western medicine group.
In conclusion the Chinese medicine composition that 1-6 of the embodiment of the present invention reduces blood glucose utilizes Poria cocos, umbellate pore furgus, raw Radix Astragali and party
Join the drug of four taste converge to the spleen channels as main ingredient, with rhizoma alismatis, cassia twig, give birth to Rhizoma Atractylodis Macrocephalae and when being classified as ministerial drug, help with turmeric, the fruit of glossy privet and ink drought
Lotus can beneficial temper, support spleen is cloudy, dry spleen is wet, let out the spleen-heat syndrome, wet spleen sun, smooth temper, logical spleen network, then supplementing qi and nourishing yin, invigorating the spleen for eliminating dampness
It is wet turbid basic that diabetes can be washed away, then realize the reduction of blood glucose.The drop can quickly, easily be prepared by the present invention
The Chinese medicine composition of hypoglycemia.
Embodiments described above is part of the embodiment of the present invention, instead of all the embodiments.The reality of the present invention
The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of the selected implementation of the present invention
Example.Based on the embodiments of the present invention, those of ordinary skill in the art are obtained without creative efforts
Every other embodiment, belongs to the scope of protection of the invention.
Claims (10)
1. a kind of Chinese medicine composition for reducing blood glucose, which is characterized in that the Chinese medicine composition for reducing blood glucose is by plurality of raw materials
It is made, in parts by weight, the plurality of raw materials includes：9-15 parts of Poria cocos, 9-12 parts of umbellate pore furgus, 9-15 parts of rhizoma alismatis, 6-9 parts of cassia twig,
15-30 parts of the fruit of glossy privet, 15-20 parts of eclipta, raw 30-60 part of Radix Astragali, 9-15 parts of Radix Codonopsis, give birth to 9-12 parts of Rhizoma Atractylodis Macrocephalae, 9-15 parts of Radix Angelicae Sinensis,
15-30 parts of 9-12 parts of turmeric and Rhizoma Dioscoreae.
2. the Chinese medicine composition according to claim 1 for reducing blood glucose, which is characterized in that in parts by weight, described a variety of
Raw material includes described Poria cocos 10-14 parts, umbellate pore furgus 10-11 parts described, rhizoma alismatis 10-14 parts described, the cassia twig 7-8 parts described, female
17-25 parts sub-, eclipta 17-18 parts described, raw Radix Astragali 35-55 parts described, Radix Codonopsis 10-13 parts described, the described raw Rhizoma Atractylodis Macrocephalae 10- of chastity
11 parts, it is Radix Angelicae Sinensis 10-14 parts described, turmeric 10-11 parts and Rhizoma Dioscoreae 17-25 parts described described.
3. the Chinese medicine composition according to claim 1 for reducing blood glucose, which is characterized in that in parts by weight, described a variety of
Raw material includes described Poria cocos 11-12 parts, umbellate pore furgus 10-11 parts described, rhizoma alismatis 12-13 parts described, the cassia twig 7-8 parts described, female
20-22 parts sub-, eclipta 17-18 parts described, raw Radix Astragali 40-45 parts described, Radix Codonopsis 11-12 parts described, the described raw Rhizoma Atractylodis Macrocephalae 10- of chastity
11 parts, it is Radix Angelicae Sinensis 11-13 parts described, turmeric 10-11 parts and Rhizoma Dioscoreae 18-20 parts described described.
4. a kind of preparation method of the Chinese medicine composition described in claim 1 for reducing blood glucose, which is characterized in that including following step
Suddenly：In parts by weight, by 9-15 parts of Poria cocos, 9-12 parts of umbellate pore furgus, 9-15 parts of rhizoma alismatis, 6-9 parts of cassia twig, 15-30 parts of the fruit of glossy privet, ink drought
15-20 parts of lotus, raw 30-60 parts of Radix Astragali, 9-15 parts of Radix Codonopsis, raw 9-12 parts of Rhizoma Atractylodis Macrocephalae, 9-15 parts of Radix Angelicae Sinensis, 9-12 parts of turmeric and Rhizoma Dioscoreae
Diacolation is carried out after 15-30 parts of mixing.
5. preparation method according to claim 4, which is characterized in that needed before carrying out diacolation by the Poria cocos, the pig
Siberian cocklebur, the rhizoma alismatis, the cassia twig, the fruit of glossy privet, the eclipta, the raw Radix Astragali, the Radix Codonopsis, the raw Rhizoma Atractylodis Macrocephalae, institute
The mixture for stating Radix Angelicae Sinensis, the turmeric and the Rhizoma Dioscoreae is moistened.
6. preparation method according to claim 5, which is characterized in that diacolation be successively using 30-40% alcoholic solvent,
The alcoholic solvent of 60-70 and the alcoholic solvent of 90-97% extract.
7. preparation method according to claim 6, which is characterized in that when needing dipping 1-3 small during each diacolation.
8. preparation method according to claim 7, which is characterized in that dipping is arranged by the air between the mixture
When dipping 1-3 is small after to the greatest extent.
9. preparation method according to claim 7, which is characterized in that with rate collection 1-3 milliliters per minute after dipping
Maceration extract.
10. the Chinese medicine composition described in claim 1 for reducing blood glucose is preparing the application in treating diabetes medicament.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103169882A (en) * | 2013-02-26 | 2013-06-26 | 孙胜波 | Traditional Chinese medicine composition for treating diabetes |
| CN103800689A (en) * | 2014-02-20 | 2014-05-21 | 丁常燕 | Traditional Chinese medicine composition for treating diabetes mellitus |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103169882A (en) * | 2013-02-26 | 2013-06-26 | 孙胜波 | Traditional Chinese medicine composition for treating diabetes |
| CN103800689A (en) * | 2014-02-20 | 2014-05-21 | 丁常燕 | Traditional Chinese medicine composition for treating diabetes mellitus |
Non-Patent Citations (1)
| Title |
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| 韩为民: "五苓散加味联合西药治疗肥胖型2型糖尿病48例", 《陕西中医学院学报》 * |
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