CN106244371B - A kind of hypoglycemic rhizoma polygonati grape health care wine and its production technology - Google Patents
A kind of hypoglycemic rhizoma polygonati grape health care wine and its production technology Download PDFInfo
- Publication number
- CN106244371B CN106244371B CN201610619543.0A CN201610619543A CN106244371B CN 106244371 B CN106244371 B CN 106244371B CN 201610619543 A CN201610619543 A CN 201610619543A CN 106244371 B CN106244371 B CN 106244371B
- Authority
- CN
- China
- Prior art keywords
- grape
- rhizoma polygonati
- wine
- fermentation
- health care
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/02—Preparation of other alcoholic beverages by fermentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Alternative & Traditional Medicine (AREA)
- Public Health (AREA)
- Botany (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention provides a kind of hypoglycemic rhizoma polygonati grape health care wine and its production technology.By grape, by first time, fermentation obtains grape wine liquid: after grape is cleaned drying or dried, going stalk broken;It is pumped into fermentor, saccharomycete is added, 18-28 DEG C of temperature control, ferments 6-10 days;When pol reaches 8-10g/L, the separation of skin slag is carried out, grape wine liquid is obtained.It is proportionally added into the traditional Chinese medicinal components such as rhizoma polygonati powder, kudzu-vine root powder and the dark plum crushed into the grape wine liquid fermented for the first time, carries out being recycled into second of fermentation immediately;Later every 8 hours progress one cycles, temperature is controlled in the range of 18-28 DEG C;Circulation 30-40 minutes every time stop circulation when pol is lower than 4g/L;Quiet fermentation under room temperature again through 6-8 weeks, switchs to lactic acid, fermentation ends to malic acid completely.The characteristics of grape wine made from the method for the present invention is pure natural, no added, and having reduces blood glucose, adjusts blood sugar for human body balance, thoroughly meets diabetes Man's Demands, blood sugar decreasing effect is good.
Description
Technical field
The present invention relates to a kind of hypoglycemic rhizoma polygonati grape health care wine and its production technologies, belong to technical field of health care food.
Background technique
Grape wine is a kind of brewed wine of low wine degree, and with a long history, flavor is delicious, full of nutrition, high character, deep by people
Like.Contained pectic substance, mucilaginous substance and various organic acids are adjustable human metabolism function;Contained minerals (including it is micro
Element) and multivitamin, it is adjustable the physiological function of human body;Contained glucose, fructose and a variety of amino acid, can direct quilt
Absorption of human body;So grape healthcare function of wine is all very paid close attention in the whole world.Modern medicine proves that grape wine, which has, restores tired
Labor promotes blood circulation, reduces hypertension, reduce blood glucose, prevention coronary heart disease, atherosclerosis, improve a poor appetite, help digest
And the effect of beauty.The active constituent resveratrol contained in red wine has the function of anti-angiocardiopathy and anticancer, institute
With, the brew of grape wine and drink the attention for being increasingly subject to people.
Although grape healthcare function of wine is more complete, more mediocre, individual event function is not protruded, and effect is unknown
Aobvious, any crowd drinks, lacks directive property, specific aim, so, people drink it as common low wine degree beverage
With.There are no for the grape wine with diabetic population development on the market at present.According to media report, Chinese patient of diabetes
Person nearly as many as 100,000,000, occupies first of the world, the healthy diet of this groups of people merits attention.So " should be drunk to solve this groups of people
It is wine, healthy again " requirement, need to research and develop the grape health care wine with special health-care efficacy.
Current existing grape health care wine, is not to research and develop for diabetes patient, and there are certain shortcomings.Example
Such as, the patent of invention of patent No. ZL201410321385.1 discloses a kind of grape brandy health preserving wine, is with grape brandy
Wine base, by weight: cortex cinnamomi 2-7%, raspberry 2-7%, fructus lycii 3-10%, rhizoma polygonati 2-5%, pueraria lobata 1-3%, Herba Cistanches 1-
5%, surplus is grape brandy, and static state low temperature immersion technology is used to make six kinds of health care food materials at alcoholic strength as 42-
48 degree of grape brandy health preserving wine.It builds up health, the effect to call forth one's youthful vigor.Preparation method is, first by grape original
Material fermentation is prepared into the grape brandy that alcoholic strength is 42-48 degree.Then by cortex cinnamomi 2-7%, raspberry 2-7%, Chinese holly under room temperature
It is 2-10 months in wine base that matrimony vine 3-10%, rhizoma polygonati 2-5%, pueraria lobata 1-3%, Herba Cistanches 1-5%, which are immersed in grape brandy,.So
And the patent impregnates technology using low temperature, the effective component of six kinds of health care food materials cannot be obtained effectively, and shadow directly after immersion
Ring the mouthfeel of grape brandy.For another example, application number 201510472735.9 is a kind of with the wintercherry grape for improving three high effects
Low-degree health care liquor and preparation method, including following parts by weight of component: wintercherry fruit 30~50, grape 200~250, tea polyphenols 5~
7, emblic fruit 10~12, Siraitia grosvenorii 8~14, radix polygonati officinalis leaching liquor 6~8, polygonatum sibiricum red juice 8~10, pueraria lobata leaching liquor 3~5, richness
Active trichoderma reesei 2~4, saccharomyces cerevisiae high activity dried yeast powder 3~5, pectase 2~3, yeast containing beta-glucosidase
Polysaccharide 3~5, gossypose 8~10, succinic acid 6~10, alditol 3~6, caramel dimethyl phthalate 4~7, chitosan 2~3, sulfurous acid
Sodium 1~2, bentonite porous material 2.3~2.7, polyvinylpyrrolidone 2.4~2.6, suitable water, through brewing.The health care
Liquor raw material ingredient is various, and contains more additive.It is not pure natural health-care grape wine.
Summary of the invention
In view of the above-mentioned deficiencies in the prior art, it is an object of the present invention to provide a kind of hypoglycemic rhizoma polygonati grape health care wine and its life
The characteristics of production. art, grape wine made from this method is pure natural, no added, and having reduces blood glucose, adjusts blood sugar for human body balance, it is thorough
Bottom meets diabetes Man's Demands, and blood sugar decreasing effect is good.
The technical scheme is that a kind of hypoglycemic rhizoma polygonati grape health care wine, grape is obtained by fermentation for the first time
Then grape wine liquid is added traditional Chinese medicinal components and carries out second being made after fermenting;The traditional Chinese medicinal components can be with hypoglycemic work
Chinese medicine, such as rhizoma polygonati, pueraria lobata, dark plum.Wherein, every liter of grape wine liquid adds 8 grams of rhizoma polygonati powder, 4 grams of kudzu-vine root powder, 2 grams of dark plum.
The first time fermentation: grape is first cleaned one time with clear water, is then cleaned with pure water spray, is dried up or dry
Afterwards, go stalk broken;Broken grape is pumped into fermentor, saccharomycete is added, grape is made to enter fermentation phase, temperature control 18-28 as early as possible
DEG C, it ferments 6-10 days;When pol reaches 8-10g/L, the separation of skin slag is carried out, grape wine liquid is obtained.
Second of fermentation: the traditional Chinese medicinal components crushed are proportionally added into the grape wine liquid fermented for the first time:
Rhizoma polygonati powder, kudzu-vine root powder and dark plum etc., are recycled immediately, merge it uniformly with grape wine liquid;One was carried out every 8 hours later
Secondary circulation, temperature control in the range of 18-28 DEG C;Circulation 30-40 minutes every time stop following when pol is lower than 4g/L
Ring;Quiet fermentation under room temperature again through 6-8 weeks, switchs to lactic acid, fermentation ends to malic acid completely.
Specifically, the production technology of the hypoglycemic rhizoma polygonati grape health care wine of the present invention, steps are as follows:
(1) raw material preparation: first being cleaned one time with clear water by grape, then cleaned with pure water spray, after drying up or drying,
Go stalk broken.Grape seed cannot be injured when broken, but ensures to scratch Grape Skin.Traditional Chinese medicinal components are removed into impurity, are crushed standby
With.
(2) ferment wine brewing
The brew of hypoglycemic rhizoma polygonati grape health care wine is in two stages, it may be assumed that fermentation for the first time and second of fermentation.
It ferments for the first time: i.e. grape fermentation.Broken grape is pumped into fermentor, saccharomycete is added, make grape as early as possible into
Enter the fermentation phase, in the range of 18-28 DEG C of temperature control, ferments 6-10 days.When pol reaches 8-10g/L, the separation of skin slag is carried out,
Grape wine liquid is obtained, second of fermentation is transferred to.
The grape wine liquid fermented for the first time: being added the traditional Chinese medicinal components crushed, is recycled immediately by second of fermentation,
Merge traditional Chinese medicinal components sufficiently uniformly with grape wine liquid;Later every 8 hours progress one cycles, temperature is controlled at 18-28 DEG C
In the range of.Circulation 30-40 minutes every time stop circulation when pol is less than 4g/L.Quiet hair under room temperature again through 6-8 weeks
Ferment switchs to lactic acid to malic acid completely.That is fermentation ends.
Then storage ageing is no less than 24 months, filters, is filling.
The hypoglycemic rhizoma polygonati grape health care wine of the present invention has significant blood sugar reducing function, and cannot carouse indiscriminate drink, often drink in right amount
It can make human body blood glucose balance, be drunk every time in 100-150ml or so, the amount of drinking is advisable no more than 400ml daily.
The hypoglycemic rhizoma polygonati grape health care wine of the present invention is with grape, rhizoma polygonati, pueraria lobata, dark plum etc. for the fermented brewing of raw material
It forms, is pure brewed wine, the beneficiating ingredient containing multiple beneficial human health, in which:
Grape: happy using the dedicated grape of black purple wine brewing, such as Cabernet Sauvignon, Cabernet franc, plum.Grape cyanine rich in
Element, polyphenols, resveratrol, amino acid rich in, protein, vitamin B1, B2, B6, C, P and carrotene
Etc. nutritional ingredients have very strong containing minerals necessary to a large amount of human bodies, such as calcium, phosphorus, potassium, selenium, iron, zinc microelement
Antioxidant activity.Grape wine is most healthy beverage, it is adjustable human metabolism, promotes blood circulation, and prevents gallbladder solid
Alcohol increases, while can also play the role of diuresis, excites liver function and prevent aging.Long-term drinking can prevent scurvy, reduce
Blood lipid, promotes digestion at softening blood vessel.
Rhizoma polygonati: Compendium of Material Medica records rhizoma polygonati: sweet and neutral, nontoxic.Tonifying middle-Jiao and Qi, curing rheumatism, five viscera settling.Long term usage, which is made light of one's life by commiting suicide, prolongs
Year is not hungry.General debility is mended, muscles and bones, resistance to cold and heat, Energy benefit taste, moistening herat and lung are helped.The essence for claiming it to obtain female soil obtains the pure essence in the world.
Modern medical research has found that rhizoma polygonati Siberian solomonseal rhizome polysaccharide rich in, oligosaccharide, niacin, lymphatic temperament, amino acid and zinc, copper, iron etc.
A variety of the essential trace elements of the human bodys can enhance cardiac contractile force, increase coronary flow, improve blood flow variable element and artery is athero-
Harden lesion.With kidney-nourishing, boosting qi and nourishing yin, invigorating the spleen, moistening lung, boosting qi and nourishing yin, moistening lung, the functions such as hypoglycemic, lipid-loweringing, decompression.For
Treat weakness of the spleen and the stomach, fatigue and asthenia, dry deficiency of food, deficiency syndrome of the lung cough caused by dryness, asthenia of essence and blood, the diseases such as Heat Diabetes.Siberian solomonseal rhizome polysaccharide is on kidney
Blood glucose caused by gland is excessively high to have apparent reduction to act on, and is the main active for inhibiting blood glucose-control blood glucose, to a- glucose
Glycosides enzyme has very strong inhibiting effect, so that disaccharide be delayed to be decomposed into the time of monosaccharide under a- glucoside enzyme effect, balances
The infiltration rate of the monosaccharide such as glucose, fructose achievees the purpose that reduce postprandial blood glucose.The postprandial hyperglycemia of duration, can
Cause a variety of physical function metabolic disorders and vascular lesion, lead to the generation and deterioration of complication, while pancreas function also will be into
One step is damaged.Rhizoma polygonati not only tonifying spleen-yin, but also beneficial temper, dual-purpose of drug and food is natural hypoglycemic medicine.
Pueraria lobata: Compendium of Material Medica records pueraria lobata: property is sweet, pungent, flat, nontoxic.The major functions: quenching one's thirst, high fever of the body, vomiting, all disadvantages, rise
Negative gas solves all poison.Dictionary of medicinal plant records pueraria lobata: [nature and flavor] are sweet, pungent, cool.[channel tropism] returns spleen, stomach meridian.[major function] expelling pathogenic factors from muscles and skin
It brings down a fever, promotes the production of body fluid, promoting eruption, Shengyang Zhixie.It is thirsty for fever caused by exogenous pathogens headache, stiff nape and back, it quenches one's thirst, measles without adequate eruption, hot dysentery is let out
It rushes down;Hypertension neck pain.Modern medicine study, pueraria lobata isoflavone compound rich in, such as Puerarin, daizeol
The nutritional ingredients such as glycosides, peanut element, there are also microelements necessary to more than the ten kinds of human bodies such as calcium, selenium, iron, copper, phosphorus, potassium, have solution
Table is brought down a fever, and is promoted the production of body fluid to quench thirst, and the function of whetting the appetite is rare invigorant suitable for people of all ages, there is the good reputation of " thousand Nian Rencan ".Have
It is apparent to reduce blood glucose, reducing blood lipid, the effect for reducing serum cholesterol, it is normal blood sugar recovery to be rapidly promoted.It is different contained by pueraria lobata
This substance of flavone compound is a kind of natural plant hormone, and the endocrine of human body can be adjusted in it, cardiac nutrition, is expanded
Blood vessel is opened, the oxygen metabolism of cardiac muscle is improved, improves microcirculation, vascular resistence is reduced, increases blood flow, therefore can be lacked with cardiac muscle is prevented and treated
Blood, myocardial infarction, arrhythmia cordis, hypertension, the illnesss such as artery sclerosis.
Dark plum: " Chinese Pharmacopoeia " load record [nature and flavor] is sour, puckery, puts down.[channel tropism] returns liver, spleen, lung, large intestine channel.[major function]
Astringing lung-QI, puckery intestines, promotes the production of body fluid, claming ascaris.For chronic cough of deficiency lung, protracted dysentery laxation, abnormal heat is quenched one's thirst, and the ascariasis of biliary tract vomits abdominal pain, ascariasis of biliary tract.It is existing
For medical research, dark plum stays the ingredients such as alcohol, promotes the production of body fluid to quench thirst, be commonly used to containing citric acid, malic acid, succinic acid, saccharide compound, paddy
Treatment such as diabetic's polydipsia quench one's thirst and pyreticosis is thirsty, dry throat disease.
The hypoglycemic rhizoma polygonati grape health care wine of the present invention increases in grape wine in addition to the nutritional ingredient with general grape wine
Siberian solomonseal rhizome polysaccharide, the sugar-lowering components such as polyphenols, pueraria isoflavone, Puerarin, organic acid effectively can draw up and adjust people
Body blood glucose greatly improves the function of reducing blood sugar of grape wine, improves the directive property of the function of grape wine.Meanwhile increasing Portugal
Microelement necessary to a variety of human bodies such as amino acid, protein, vitamin and calcium, selenium, iron, copper, phosphorus, potassium in grape wine.
Hypoglycemic rhizoma polygonati grape health care wine of the invention, rubbing up and interacting for plurality of active ingredients enhance grape
The hypoglycemic element of wine, adjusts the function of spleen, stomach, kidney, and nutritious cardiac muscle, and expansion blood vessel improves microcirculation, blood pressure lowering, drop
Rouge, softening cardiovascular and cerebrovascular, tonifying middle-Jiao and Qi, nourishing YIN for benefiting the kidney, prolongs life and other effects at norcholesterol.Myocardial ischemia can be prevented and treated, cardiac muscle
Infarct, blood glucose complication, hypertension, the illnesss such as hyperlipidemia, artery sclerosis.
Different traditional Chinese medicinal components are added as needed, such as with hoveniae semoveniae semen, radix polygonati officinalis, sea-buckthorn, mulberries, the heart of a lotus seed of hypoglycemic effect
Seed of jog's tears etc.;Hawthorn with effect for reducing blood fat;Chrysanthemum with hypotensive activity;Clearing heat and detoxicating honeysuckle;Antitoxic heart-soothing and sedative
Semen ziziphi spinosae;The grape health of different efficacies can be obtained in the Chinese medicine of the dual-purpose of drug and food such as fructus lycii, Chinese yam, the arillus longan of nourishing kidney-YIN
Wine.Preparation method is added in second of fermentation with aforementioned, that is, can be prepared into hypoglycemic and/or reducing blood lipid, by blood
The grape health care wine of pressure, enriching yin and nourishing kidney and other effects.
The present invention innovates on raw material and technique:
1, raw material is innovated
(1) select vinifera have special requirement.It must be the grape age of tree at 10 years or more, plant is healthy, fringe
Big maturity is good, and pol reaches 200g/L or more, generally 60 centimeters or so of grape from the ground.Because of the bigger grape of the age of tree
Nutriment is abundanter, and plant health grape miscellaneous bacteria infection rate is small, and pol is high.
(2) Chinese medicine of the integration of drinking and medicinal herbs such as rhizoma polygonati, pueraria lobata, dark plum is increased newly in wine production.Siberian solomonseal rhizome polysaccharide is to inhibit blood
Sugar adjusts the main active of blood glucose, has very strong inhibiting effect to human body a- glucuroide, to delay disaccharide
It is decomposed into the time of monosaccharide under a- glucoside enzyme effect, has slowed down human body to the infiltration rate of the monosaccharide such as glucose, fructose,
And then achieve the purpose that reduction and balance blood sugar.This substance of pueraria isoflavone class compound is a kind of natural plant hormone, energy
Promote the fast quick-recovery of postprandial blood sugar normal, and have and the endocrine of human body is adjusted, cardiac nutrition expands blood vessel, promotes the production of body fluid
The effect of quenching the thirst.Dark plum organic acid can exciting salivary secretion, promote the production of body fluid to quench thirst, to eliminate diabetic's polydipsia, pyreticosis mouth
Yearningly, the diseases such as dry throat have good relaxation effect.By fermenting twice, to grape, rhizoma polygonati, pueraria lobata, dark plum plurality of active ingredients into
Extraction of having gone rubs up, and increases the medicinal blood sugar reducing component of grape wine, and rhizoma polygonati grape wine is made to be provided with the function for adjusting spleen, stomach, kidney
It can be with significant effect of lowering blood sugar.
2, process innovation
(1) impurity technique is removed using physical method control miscellaneous bacteria.In the pretreatment process of grape, traditional way is only gone
The sundries for falling grape ear entrainment, is not cleaned generally, and control miscellaneous bacteria is to add chemical preservative sulfur dioxide i.e. after Grape fragmentation
Chemical Control.The present invention increases the spray washing of purified water on the basis of first time clear water washs, and utilizes purified water
Absorption and reproducibility, the miscellaneous bacteria on physical removal grape berry surface and impurity, are fully achieved instant standard, to reach physical control
The purpose of miscellaneous bacteria.
(2) in first time fermentation, skin slag separating technology is shifted to an earlier date using grape fermentation.General grape wine is in fermentation, sugar
Degree reaches 5g/L or so and carries out the separation of skin slag, i.e. alcoholic fermentation terminates.This technique is in pol 10g/L or so with regard to carrying out skin slag point
From being conducive to the precipitation of the traditional Chinese medicinal components effective component such as rhizoma polygonati, pueraria lobata, dark plum to increase the activity of second fermentation.
(3) in second of fermentation, using lag separating technology.Second of fermentation time is increased, grape wine liquid is made
To the traditional Chinese medicinal components effective component such as rhizoma polygonati, pueraria lobata, dark plum is fully hydrolyzed, water mentions and alcohol extracting, effective component is precipitated completely,
The effect of ensure that rhizoma polygonati grape wine.During secondary fermentation, heat and carbon dioxide gas can be constantly generated, utilizes two
Carbonoxide takes taking property, and volatile materials in the traditional Chinese medicinal components such as rhizoma polygonati, pueraria lobata, dark plum is made constantly to volatilize, and dispelling abnormal flavor makes wine body
Mouthfeel is purer;Contained sugar, starch are constantly degraded under the action of saccharomycete, are generated alcohol, are increased the alcohol thickness of wine body;
Under temperature, water and alcohol function, the sugar-lowering components in the traditional Chinese medicinal components such as rhizoma polygonati, pueraria lobata, dark plum are constantly precipitated, and (utilize Huang
The dissolubility of the effective components such as essence, pueraria lobata, dark plum completes the overall process of hydrolysis and alcohol extracting) save rhizoma polygonati, pueraria lobata, dark plum etc.
The natural sex ingredient of traditional Chinese medicinal components strengthens polyphenols, Siberian solomonseal rhizome polysaccharide, pueraria isoflavone, Puerarin, organic acid in grape wine
And the sugar-lowering components such as biologically active peptide.Meanwhile increase amino acid in grape wine, protein, vitamin and calcium, selenium, iron, copper,
Microelement necessary to a variety of human bodies such as phosphorus, potassium.
Specific embodiment
Below by embodiment, the invention will be further described, but practical range of the invention is not limited to this.
Embodiment one
1, the selection of raw material
(1) grape: the grape age of tree was at 10 years or more, and plant health, the big maturity of fringe is good, and pol is in 200g/kg, kind
Cabernet Sauvignon, weight 5000kg.
(2) rhizoma polygonati: raw sealwort, a big plumpness, weight matter is hard and softness person is preferred.Surface brown color, section yellow-white, sugar
Property foot, free from admixture.
(3) pueraria lobata: Wild Pueraria, it is hard with matter and weigh, section is coarse, rich mealiness, and containing a large amount of fibers, cross section it is visible by
Fiber is formed by concentric circles, and the visible fiber of longitudal section is alternate with bisque, forms longitudinal grin, and that hears is tasteless, and mouth gustation is slightly sweet.
(4) dark plum: natural sun-dried dark plum, a pork are thick.
2, cleaning is broken
(1) grape: grape is first cleaned one time with clear water before broken, is then cleaned with pure water spray, grape is dried up
Or after drying, go stalk broken.Grape seed cannot be injured when broken, but ensures to scratch Grape Skin.
(2) rhizoma polygonati: removal impurity is ground into fine granularity.
(3) pueraria lobata: removal impurity is ground into fine granularity.
(4) dark plum: removal impurity flattens the shape that is cut into small pieces.
3 ferment wine brewings
It ferments for the first time, i.e., to grape fermentation.Broken grape is pumped into fermentor, saccharomycete (saccharomycete is added immediately
Access amount is this field conventional amount used), so that grape is entered the fermentation phase as early as possible, controls temperature in the range of 18-28 DEG C,
Fermentation 6 days.Wine liquid pol is 10g/L, and skin slag is separated, grape wine liquid 3150kg is obtained, is transferred to second of fermentation.
Second of fermentation: the grape wine liquid fermented for the first time is added to the rhizoma polygonati powder 25.2kg crushed, kudzu-vine root powder
12.6kg, dark plum 6.3kg (adding proportion is that every liter of grape wine liquid adds 8 grams of rhizoma polygonati powder, 4 grams of kudzu-vine root powder, 2 grams of dark plum) are carried out immediately
Circulation, merges rhizoma polygonati powder, kudzu-vine root powder, dark plum sufficiently uniformly with grape wine liquid.Later every 8 hours progress one cycles, temperature
Degree control is in the range of 18-28 DEG C.Circulation 30 minutes every time, Time Continuous are 7 days, pol 3.8g/L, stop circulation,
Quiet fermentation under into room temperature.Through 6 weeks normal temperature fermentations, malic acid switched to lactic acid completely.
4, it stores
The wine liquid fermented is separated, rhizoma polygonati, pueraria lobata, dark plum sediment are removed, storage in injection storage tank uses nitrogen
Sealing gland wine face, tightens upper cover, into the storage ageing phase.Storage 24 months.
5, it filters
The rhizoma polygonati grape wine stored is filtered with plate-sheet-type microfroc filter, further removes the large particle in wine liquid
Money and floating material, keep wine body sparkling and crystal-clear bright.
6, filling
Bottle stopper is sterilized with ultraviolet light, completes filling, gland, labeling, dress into automatic filling line with purified water wash bottle
Case.General flavone content 285mg/L, sugar-free extract 23.5mg/L.
Embodiment two
1, the selection of raw material
(1) grape: the grape age of tree was at 10 years or more, and plant health, the big maturity of fringe is good, and pol is in 210g/kg, kind
Cabernet Sauvignon, weight 10000kg.
(2) rhizoma polygonati: raw sealwort, a big plumpness, weight matter is hard and softness person is preferred.Surface brown color, section yellow-white, sugar
Property foot, free from admixture.
(3) pueraria lobata: Wild Pueraria, matter weighs firmly, section is coarse, rich mealiness, and contains a large amount of fibers, and cross section is visible by fibre
Dimension is formed by concentric circles, and the visible fiber of longitudal section is alternate with bisque, forms longitudinal grin, and that hears is tasteless, and mouth gustation is slightly sweet.
(4) dark plum: natural sun-dried dark plum, a pork are thick.
(5) hawthorn: big with fruit, meat is thick, core is small, Pi Hongzhe is preferred.
2, cleaning is broken
(1) grape: grape is first cleaned one time with clear water before broken, is then cleaned with pure water spray, grape is dried up
Or after drying, go stalk broken.Grape seed cannot be injured when broken, but ensures to scratch Grape Skin.
(2) rhizoma polygonati: removal impurity is ground into fine granularity.
(3) pueraria lobata: removal impurity is ground into fine granularity.
(4) dark plum: removal impurity flattens the shape that is cut into small pieces.
(5) hawthorn: removal impurity flattens the shape that is cut into small pieces.
3, ferment wine brewing
It ferments for the first time, i.e., to grape fermentation.Broken grape is pumped into fermentor, saccharomycete (saccharomycete is added immediately
Access amount is this field conventional amount used), so that grape is entered the fermentation phase as early as possible, controls temperature in the range of 18-28 DEG C,
Fermentation 7 days.Wine liquid pol is 8.5g/L, and skin slag is separated, grape wine liquid 6250kg is obtained, is transferred to second of fermentation.
The grape wine liquid fermented for the first time: being added rhizoma polygonati powder 50kg, the kudzu-vine root powder 25kg crushed by second of fermentation,
(adding proportion is that every liter of grape wine liquid adds 8 grams of rhizoma polygonati powder, 4 grams of kudzu-vine root powder, 2 grams of dark plum, hawthorn 4 by dark plum 12.5kg, hawthorn 25kg
Gram) recycled immediately, merge rhizoma polygonati powder, kudzu-vine root powder, dark plum and hawthorn etc. sufficiently uniformly with grape wine liquid.It is later small every 8
Shi Jinhang one cycle, temperature control in the range of 18-28 DEG C.Circulation 30 minutes every time, Time Continuous are 7 days, and pol is
3.7g/L, stop circulation, into room temperature under quiet fermentation.Through 45 days normal temperature fermentations, malic acid switched to lactic acid completely.
4, (ageing) is stored
The wine liquid fermented is separated, rhizoma polygonati, pueraria lobata, dark plum and hawthorn sediment, storage in injection storage tank are removed
Hiding seals wine face with nitrogen, tightens upper cover, into the storage ageing phase.Storage 24 months.
5, it filters
The rhizoma polygonati grape wine stored is filtered with plate-sheet-type microfroc filter, further removes the large particle in wine liquid
Money and floating material keep wine body brilliant crystal-clear bright.
6, filling
Bottle stopper is sterilized with ultraviolet light, completes filling, gland, labeling, dress into automatic filling line with purified water wash bottle
Case.General flavone content 288mg/L, sugar-free extract 24mg/L.
Embodiment three
1, the selection of raw material
(1) grape: the grape age of tree was at 10 years or more, and plant health, the big maturity of fringe is good, and pol is in 215g/kg, kind
Cabernet Sauvignon, weight 15000kg.
(2) rhizoma polygonati: raw sealwort, a big plumpness, weight matter is hard and softness person is preferred.Surface brown color, section yellow-white, sugar
Property foot, free from admixture.
(3) pueraria lobata: Wild Pueraria, matter weighs firmly, section is coarse, rich mealiness, and contains a large amount of fibers, and cross section is visible by fibre
Dimension is formed by concentric circles, and the visible fiber of longitudal section is alternate with bisque, forms longitudinal grin, and that hears is tasteless, and mouth gustation is slightly sweet.
(4) dark plum: natural sun-dried dark plum, a pork are thick.
(5) Chinese yam: selecting high-quality Chinese yam, and Chinese yam rhizome is best.
(6) fructus lycii: high-quality lycium barbarum.
2, cleaning is broken
(1) grape: grape is first cleaned one time with clear water before broken, is then cleaned with pure water spray, grape is dried up
Or after drying, go stalk broken.Grape seed cannot be injured when broken, but ensures to scratch Grape Skin.
(2) rhizoma polygonati: removal impurity is ground into fine granularity.
(3) pueraria lobata: removal impurity is ground into fine granularity.
(4) dark plum: removal impurity flattens the shape that is cut into small pieces.
(5) Chinese yam: removing impurity, separates size, and bubble profit cuts sheet to saturating, dry.
(6) fructus lycii: removal impurity is ground into fine granularity.
3, ferment wine brewing
It ferments for the first time, i.e., to grape fermentation.Broken grape is pumped into fermentor, saccharomycete (saccharomycete is added immediately
Access amount is this field conventional amount used), so that grape is entered the fermentation phase as early as possible, controls temperature in the range of 18-28 DEG C,
Fermentation 7 days.Wine liquid pol is 9g/L, and skin slag is separated, grape wine liquid 9450kg is obtained, is transferred to second of fermentation.
Second of fermentation: the grape wine liquid fermented for the first time is added to the rhizoma polygonati powder 75.6kg crushed, kudzu-vine root powder
37.8kg, dark plum 19.8kg, Chinese yam 19.8kg, fructus lycii 19.8kg (adding proportion be every liter of grape wine liquid add 8 grams of rhizoma polygonati powder,
4 grams of kudzu-vine root powder, 2 grams of dark plum, 2 grams of Chinese yam, 2 grams of fructus lycii) it is recycled immediately, make rhizoma polygonati powder, kudzu-vine root powder, dark plum, Chinese yam, Chinese holly
Matrimony vine etc. is sufficiently uniformly merged with grape wine liquid.Later every 8 hours progress one cycles, model of the temperature control at 18-28 DEG C
In enclosing.Every time circulation 30 minutes, Time Continuous be 7 days, pol 3.9g/L, stop circulation, into room temperature under quiet fermentation.Through 49
Its normal temperature fermentation, malic acid switch to lactic acid completely.
4, it stores
The wine liquid fermented is separated, the sediments such as removal rhizoma polygonati, pueraria lobata, dark plum, Chinese yam, fructus lycii, injection storage
Storage in tank is hidden, wine face is sealed with nitrogen, tightens upper cover, into the storage ageing phase.Storage 24 months.
5, it filters
The rhizoma polygonati grape wine stored is filtered with plate-sheet-type microfroc filter, further removes the large particle in wine liquid
Money and floating material keep wine body brilliant crystal-clear bright.
6, filling
Bottle stopper is sterilized with ultraviolet light, completes filling, gland, labeling, dress into automatic filling line with purified water wash bottle
Case.General flavone content 280mg/L, sugar-free extract 24.6mg/L.
Example IV
1, the selection of raw material
(1) grape: the grape age of tree was at 10 years or more, and plant health, the big maturity of fringe is good, and pol is in 221g/kg, kind
Cabernet Sauvignon, weight 16000kg.
(2) rhizoma polygonati: raw sealwort, a big plumpness, weight matter is hard and softness person is preferred.Surface brown color, section yellow-white, sugar
Property foot, free from admixture.
(3) pueraria lobata: Wild Pueraria, matter weighs firmly, section is coarse, rich mealiness, and contains a large amount of fibers, and cross section is visible by fibre
Dimension is formed by concentric circles, and the visible fiber of longitudal section is alternate with bisque, forms longitudinal grin, and that hears is tasteless, and mouth gustation is slightly sweet.
(4) dark plum: natural sun-dried dark plum, a pork are thick.
(5) chrysanthemum: natural high-quality wild chrysanthemum.
2, cleaning is broken
(1) grape: grape is first cleaned one time with clear water before broken, is then cleaned with pure water spray, grape is dried up
Or after drying, go stalk broken.Grape seed cannot be injured when broken, but ensures to scratch Grape Skin.
(2) rhizoma polygonati: removal impurity is ground into fine granularity.
(3) pueraria lobata: removal impurity is ground into fine granularity.
(4) dark plum: removal impurity flattens the shape that is cut into small pieces.
(5) chrysanthemum: removal impurity crushes.
3, ferment wine brewing
It ferments for the first time, i.e., to grape fermentation, broken grape is pumped into fermentor, saccharomycete (saccharomycete is added immediately
Access amount is this field conventional amount used), so that grape is entered the fermentation phase as early as possible, controls temperature in the range of 18-28 DEG C,
Fermentation 7 days.Wine liquid pol is 9.5g/L, and skin slag is separated, grape wine liquid 10240kg is obtained, is transferred to second of fermentation.
The grape wine liquid fermented for the first time: being added rhizoma polygonati powder 82kg, the kudzu-vine root powder 41kg crushed by second of fermentation,
(adding proportion is that every liter of grape wine liquid adds 8 grams of rhizoma polygonati powder, 4 grams of kudzu-vine root powder, 2 grams of dark plum, chrysanthemum by dark plum 20.5kg, chrysanthemum 30.75kg
Spend 3 grams) it is recycled immediately, merge rhizoma polygonati powder, kudzu-vine root powder, dark plum, chrysanthemum sufficiently uniformly with grape wine liquid.Later every 8
Hour carries out one cycle, and temperature controls in the range of 18-28 DEG C.Circulation 30 minutes every time, Time Continuous are 8 days, pol
For 2.9g/L, stop circulation, into room temperature under quiet fermentation.Through 49 days normal temperature fermentations, malic acid switched to lactic acid completely.
4, it stores
The wine liquid fermented is separated, the sediments such as removal rhizoma polygonati, pueraria lobata, dark plum, chrysanthemum, storage in injection storage tank
Hiding seals wine face with nitrogen, tightens upper cover, into the storage ageing phase.Storage 24 months.
5, it filters
The rhizoma polygonati grape wine stored is filtered with plate-sheet-type microfroc filter, further removes the large particle in wine liquid
Money and floating material keep wine body brilliant crystal-clear bright.
6, filling
Bottle stopper is sterilized with ultraviolet light, completes filling, gland, labeling, dress into automatic filling line with purified water wash bottle
Case.General flavone content 283mg/L, sugar-free extract 25.2mg/L.
Embodiment five
1, the selection of raw material
(1) grape: the grape age of tree was at 10 years or more, and plant health, the big maturity of fringe is good, and pol is in 230g/kg, kind
Cabernet Sauvignon, weight 18000kg.
(2) rhizoma polygonati: raw sealwort, a big plumpness, weight matter is hard and softness person is preferred.Surface brown color, section yellow-white, sugar
Property foot, free from admixture.
(3) pueraria lobata: Wild Pueraria, matter weighs firmly, section is coarse, rich mealiness, and contains a large amount of fibers, and cross section is visible by fibre
Dimension is formed by concentric circles, and the visible fiber of longitudal section is alternate with bisque, forms longitudinal grin, and that hears is tasteless, and mouth gustation is slightly sweet.
(4) dark plum: natural sun-dried dark plum, a pork are thick.
(5) chrysanthemum: natural high-quality wild chrysanthemum.
(6) hawthorn: big with fruit, meat is thick, core is small, Pi Hongzhe is preferred.
(7) semen ziziphi spinosae: oblate or flat ellipse, surface aubergine or puce, it is smooth glossy or have the excellent of crackle
Matter semen ziziphi spinosae.
2, cleaning is broken
(1) grape: grape is first cleaned one time with clear water before broken, is then cleaned with pure water spray, grape is dried up
Or after drying, go stalk broken.Grape seed cannot be injured when broken, but ensures to scratch Grape Skin.
(2) rhizoma polygonati: removal impurity is ground into fine granularity.
(3) pueraria lobata: removal impurity is ground into fine granularity.
(4) dark plum: removal impurity flattens the shape that is cut into small pieces.
(5) chrysanthemum: removal impurity crushes.
(6) hawthorn: removal impurity flattens the shape that is cut into small pieces.
(7) semen ziziphi spinosae: removal impurity crushes.
3, ferment wine brewing
It ferments for the first time, i.e., to grape fermentation.Broken grape is pumped into fermentor, saccharomycete (saccharomycete is added immediately
Access amount is this field conventional amount used), so that grape is entered the fermentation phase as early as possible, in the range of control is 18-28 DEG C warm, fermentation 8
It.Wine liquid pol is 8.8g/L, and skin slag is separated, grape wine liquid 10240kg is obtained, is transferred to second of fermentation.
The grape wine liquid fermented for the first time: being added rhizoma polygonati powder 82kg, the kudzu-vine root powder 41kg crushed by second of fermentation,
(adding proportion is that every liter of grape wine liquid adds rhizoma polygonati by dark plum 20.5kg, chrysanthemum 30.75kg, hawthorn 30.75kg, semen ziziphi spinosae 20.5kg
8 grams of powder, 4 grams of kudzu-vine root powder, 2 grams of dark plum, 3 grams of chrysanthemum, 3 grams of hawthorn, 2 grams of semen ziziphi spinosae) it is recycled immediately, make rhizoma polygonati powder, pueraria lobata
Powder, dark plum, chrysanthemum powder, hawthorn, spiny jujuba seed powder etc. are sufficiently uniformly merged with grape wine liquid.It was once followed every 8 hours later
Ring, temperature control in the range of 18-28 DEG C.Circulation 30 minutes every time, Time Continuous are 8 days, pol 2.9g/L, are stopped
Circulation, into room temperature under quiet fermentation.Through 49 days normal temperature fermentations, malic acid switched to lactic acid completely.
4, it stores
The wine liquid fermented is separated, the sediments such as removal rhizoma polygonati, pueraria lobata, dark plum, chrysanthemum, hawthorn, semen ziziphi spinosae, note
Enter storage in storage tank, seal wine face with nitrogen, tighten upper cover, into the storage ageing phase.Storage 24 months.
5, it filters
The rhizoma polygonati grape wine stored is filtered with plate-sheet-type microfroc filter, further removes the large particle in wine liquid
Money and floating material keep wine body brilliant crystal-clear bright.
6, filling
Bottle stopper is sterilized with ultraviolet light, completes filling, gland, labeling, dress into automatic filling line with purified water wash bottle
Case.General flavone content 290mg/L, sugar-free extract 26.1mg/L.
Embodiment six
The rhizoma polygonati grape health care wine that embodiment one to five is obtained, specification are 750ml/ bottles, 17%vol, send to city-level and eat
Product drug inspection inspection center, tests, and inspection project has: color, clarity, fragrance, taste, style, alcoholic strength, total
Sugar, volatile acid (with Acetometer), total sulfur dioxide are (with SO2Meter), sugar-free extract, flavones, iron, copper, lead, potassium sorbate, methanol,
Pathogenic bacteria (salmonella, staphylococcus aureus, Shigella), total plate count, coliform, benzoic acid and sodium benzoate, peace
Match honey, saccharin sodium, honey element, amaranth and its aluminum lake, famille rose and its aluminum lake.Inspection result is shown in Table 1.
The rhizoma polygonati grape health care wine inspection result of the present invention of table 1
Below in conjunction with animal function test and tries out case and further illustrate its advantages.
Animal function test example
1. material
1.1 subject materials: rhizoma polygonati grape health care wine of the present invention
1.2 experimental animal
Kunming mouse, weight 18-22g, in room temperature (24 ± 2) DEG C, the laboratory of relative humidity (55 ± 10) % is raised,
Free water, fed granules feed.
2. method
Research of the 2.1 rhizoma polygonati grape health care wines of the present invention to diabetic mice hypoglycemic effect
Take kunming mice 60 of weight 18-22g, every group 20, half male and half female.It is phonetic that 2% 4 oxygen is made into physiological saline
Pyridine injection is injected intraperitoneally the mouse after fasting 12h by the dosage of alloxan solution 200mg/kg.Continuous raising
After 3d, fasting 12h, eye socket blood sampling separates serum, measures fasting blood-glucose, is greater than 13mmol/L as diabetes mould using blood glucose value
Type mouse.
After modeling successfully, diabetic mice 40 are chosen, every group 20, female is fifty-fifty, is randomly divided into rhizoma polygonati grape
Health liquor group and model control group.Normal Kunming mouse 20 are separately taken similar in quality, and female is fifty-fifty, as normal control
Group.The daily stomach-filling 0.3ml rhizoma polygonati grape health care wine of rhizoma polygonati grape health care wine group.Model control group and Normal group feed stomach-filling
The physiological saline of same volume, once a day, continuous 15d.
The change of observation mouse macroscopic features daily, and the fasting 12h after last stomach-filling, eye socket blood sampling, 3500r/min from
Heart 10min separates and collects serum, measures fasting blood-glucose.
Research of the 2.2 rhizoma polygonati grape health care wines of the present invention to high blood lipid model mouse effect for reducing blood fat
Kunming mice 60 of weight 18-22g are taken, every group 20, half male and half female is randomly divided into rhizoma polygonati grape health care wine
Group, model control group and Normal group.Rhizoma polygonati grape health care wine group, model control group mouse feed high lipid food, normal right
According to a group feeding basal feed, continuous feeding two weeks.After modeling successfully, the daily stomach-filling 0.3ml rhizoma polygonati Portugal of rhizoma polygonati grape health care wine group
Grape health liquor.The physiological saline of model control group and Normal group feeding stomach-filling same volume, continuous two weeks.In after the last administration
Fasting 12h, eye socket blood sampling, 3500r/min are centrifuged 10min, separate and collect serum, measure TG, TC, HDL-C and LDL-C in serum
Content.
3. result
Result of study of the 3.1 rhizoma polygonati grape health care wines of the present invention to diabetic mice hypoglycemic effect
2 rhizoma polygonati grape health care wine of table to diabetic mice blood glucose influence (N=20) mmol/L
Note: * * p < 0.01, * p < 0.05 compared with model control group.
As shown in Table 2, the blood sugar concentration of model control group is extremely significant is higher than Normal group.Show diabetic mice
Modeling success.Compared with model control group, the reduction of rhizoma polygonati grape health care wine group blood sugar concentration is extremely significant, shows rhizoma polygonati grape health
Wine group, which reduces blood glucose to diabetic mice, certain influence.
Result of study of the 3.2 rhizoma polygonati grape health care wines of the present invention to high blood lipid model mouse effect for reducing blood fat
3 rhizoma polygonati grape health care wine of table to TG in high blood lipid model mice serum, TC, HDL-C, the influence of LDL-C (n
=20) mmol/L
Note: * * p < 0.01, * p < 0.05 compared with model control group.
As shown in Table 3, model control group serum TG is significantly higher than Normal group, shows that high blood lipid model is set up.Stomach-filling
After drinking, for rhizoma polygonati grape health care wine group compared with model control group, TG has extremely significant reduction to rhizoma polygonati grape health, shows rhizoma polygonati grape
Health liquor has extremely significant effect to serum TG is reduced;HDL-C raising is extremely significant, shows that rhizoma polygonati grape health care wine can be increased effectively
HDL-C.Other two variations are less significant compared with model control group.
Show that the rhizoma polygonati grape health care wine of stomach-filling 0.3ml/d has centainly diabetic mice through results of animal
Hypoglycemic effect, to high blood lipid model mouse have effect for reducing blood fat.
Try out example
1. Zhang, male, 59 years old.There are thirsty, more drinks, diuresis without bright reason before patient 4 years, gradually thin and lower limb are floating
It is swollen to wait performance, check that blood glucose is high through hospital, diagnosis are as follows: type II diabetes gives the antidiabetic drugs such as Metformin hydrochloride, gliclazide
Object therapeutic effect is unobvious, after while taking hypoglycemic medicine, give take the hypoglycemic rhizoma polygonati grape of the embodiment of the present invention one guarantor
Strong wine, twice daily (lunch, dinner), each 100ml, take after two weeks, survey blood glucose and are gradually reduced, the symptoms were significantly improved.Clothes
After a course for the treatment of (a month as a treatment course), hypoglycemic medicine dose halves, and the performances such as thirsty, more drinks, diuresis gradually disappear
Lose, spirit, complexion and and edema of lower extremity be clearly better.It is normal, stable to continue taking the two courses rear blood glucose, hypoglycemic medicine stops
Clothes, advise reasonable diet, moderate exercise, follow-up half a year, no relapse.
2. Meng so-and-so, male, 64 years old.Diabetes mellitus 3 years, usually self-induction polyorexia, polydipsia, out of strength, loose stool etc.
Performance.It surveys between fasting blood-glucose 8.2-10.0mmol/l, between postprandial blood sugar 12.6-17.5mmol/l, glucose in urine 2-3+;It takes always
It is treated with hypoglycemic medicine and subcutaneous insulin injections, weight when symptom is light, glycemic control is undesirable.Through taking the embodiment of the present invention
One hypoglycemic rhizoma polygonati grape health care wine treats 2 courses for the treatment of (a month as a treatment course), and gradually successively decrease insulin dosage, above-mentioned disease
Shape mitigates, and continues to deactivate insulin after taking 2 course for the treatment of, and all malaise symptoms disappear, glycemic control 6.2-7.4mmol/l it
Between, glucose in urine (-), blood glucose is normal, stable after continuing to strengthen 1 course for the treatment of of treatment, is now in a good state of health.
3. Mr. Wang, female, 51 years old.Body is fine always before this by patient, and physical examination in 2014 when has found hypertension, height
Blood lipid, high blood viscosity symptom, blood pressure can have 120-180, the diseases such as dizziness, headache, general weakness often occur.2 months 2015
Part laboratory indexes on the 25th are as follows: triglycerides 1.79, total cholesterol 6.25, high density lipoprotein 1 .33, low-density lipoprotein
White 3.51.Because patient has a liking for drinking usually, start to drink the grape health care wine of the embodiment of the present invention five in June, 2015,7 days
Afterwards, it is just alleviated the case where dizzy headache, the time blood pressure less than one month just drops to 90-130, checks to hospital, blood lipid
It drops.The laboratory indexes on July 17th, 2015 are as follows: triglycerides 1.16, total cholesterol 5.28, high density lipoprotein 1 .15, low
Density lipoprotein 3.82.Continue to take one month, on August 17th, 2015 is chemically examined, the index of above-mentioned item are as follows: triglycerides again
0.99, total cholesterol 3.97, high density lipoprotein 1 .23, low-density lipoprotein 2.41.So far blood pressure is very stable always for follow-up, respectively
Item index is all normal.
4. Chen, female, 49 years old, patient's two years ago often felt polyorexia, polydipsia, dizziness, headache, general weakness.Through
Check that on March 4th, 2015, part laboratory indexes were as follows with the illnesss such as hypertension, hyperlipidemia, hyperglycemia: glucose 9.69, sweet
Oily three esters 15.57, total cholesterol 14.29, high density lipoprotein 1 .03, low-density lipoprotein 7.86.Many medicines are eaten, blood pressure is anti-
It is multiple unstable, make patient very worried.Therefore the embodiment of the present invention is drunk on the basis of taking drugs since on March 15th, 2015
Five grape health care wine, on April 5th, 2015 chemically examines again after 1 course for the treatment of, These parameters are as follows: glucose 7.98, triglycerides
8.92, total cholesterol 9.81, high density lipoprotein 1 .36, low-density lipoprotein 4.02.It is chemically examined again after persistently drinking half a year: Portugal
Grape sugar 5.94, triglycerides 1.92, total cholesterol 5.90, high density lipoprotein 1 .42, low-density lipoprotein 2.02.
Conclusion: the patient for often suffering from diabetes should forbid drinking, because on the one hand, drinking and will increase burden of liver,
And the liver detoxification ability of diabetes patient is poor, the burden of liver will certainly be aggravated and cause to damage by drinking.Meanwhile it being also easy to send out
Raw hyperlipidemia and metabolic disorder.Diabetes are mainly caused by hypoinsulinism.Drinking can make pancreas be stimulated and shadow
Ring the ingredient of its juice.Wine inherently high heat food, every gram of alcohol can produce 7 kilocalories of heats, diabetes patient's system slightly out of control,
It can cause that sb.'s illness took a turn for the worse.And there are no for the grape wine with diabetic population development on the market at present.So to solve
The requirement of this groups of people's " should drink, healthy again ", needs to research and develop the grape health care wine with special health-care efficacy.The present invention
It is made using the Chinese medicine with hypoglycemic effect with grape wine co-fermentation, belongs to mild health care drink.It is ground through zoopery
Study carefully and shows that rhizoma polygonati grape health care wine of the present invention has the function of certain hypoglycemic, reducing blood lipid.And it can be drunk in duration of medication.
Some patientss are voluntarily tried out, and show that reducing blood sugar and blood fat works well.
Claims (4)
1. a kind of hypoglycemic rhizoma polygonati grape health care wine, characterized in that grape is obtained grape wine liquid by fermentation for the first time, then
Traditional Chinese medicinal components are added to carry out second being made after fermenting;
The hypoglycemic rhizoma polygonati grape health care wine is prepared by following technique:
(1) raw material preparation: grape is cleaned one time with clear water first, is then cleaned with pure water spray, after drying up or drying, goes to obstruct
It is broken;Traditional Chinese medicinal components are removed into impurity, are crushed spare;
(2) ferment wine brewing
It ferments for the first time, i.e. grape fermentation: broken grape being pumped into fermentor, saccharomycete is added, grape is made to enter hair as early as possible
The ferment phase ferments 6-10 days in the range of 18-28 DEG C of temperature control, when pol reaches 8-10g/L, carries out the separation of skin slag, obtains Portugal
Grape wine liquid is transferred to second of fermentation;
Second ferment: the grape wine liquid fermented for the first time being added to the traditional Chinese medicinal components crushed, is recycled immediately, is made
Medicine component is sufficiently uniformly merged with grape wine liquid;Later every 8 hours progress one cycles, model of the temperature control at 18-28 DEG C
In enclosing;Circulation 30-40 minutes every time stop circulation when pol is less than 4g/L;Quiet fermentation under room temperature again through 6-8 weeks, to
Malic acid switchs to lactic acid, i.e. fermentation ends completely;
Then storage ageing is no less than 24 months, filters, is filling;
The traditional Chinese medicinal components include rhizoma polygonati, pueraria lobata, dark plum.
2. hypoglycemic rhizoma polygonati grape health care wine as described in claim 1, characterized in that the traditional Chinese medicinal components dosage is every liter
Grape wine liquid adds 8 grams of rhizoma polygonati, 4 grams of pueraria lobata, 2 grams of dark plum.
3. hypoglycemic rhizoma polygonati grape health care wine as claimed in claim 1 or 2, characterized in that the traditional Chinese medicinal components further include trifoliate orange
One of Dulcis, radix polygonati officinalis, sea-buckthorn, mulberries, semen coicis, hawthorn, chrysanthemum, honeysuckle, semen ziziphi spinosae, fructus lycii, Chinese yam, arillus longan
Or it is several.
4. hypoglycemic rhizoma polygonati grape health care wine as described in claim 1 or 2 is any, characterized in that the grape, using the age of tree
At 10 years or more, plant health, the big maturity of fringe was good, and pol reaches 200g/L or more, from the ground 60 centimeters of grape.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610619543.0A CN106244371B (en) | 2016-07-29 | 2016-07-29 | A kind of hypoglycemic rhizoma polygonati grape health care wine and its production technology |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610619543.0A CN106244371B (en) | 2016-07-29 | 2016-07-29 | A kind of hypoglycemic rhizoma polygonati grape health care wine and its production technology |
Publications (2)
Publication Number | Publication Date |
---|---|
CN106244371A CN106244371A (en) | 2016-12-21 |
CN106244371B true CN106244371B (en) | 2019-11-15 |
Family
ID=57606741
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610619543.0A Active CN106244371B (en) | 2016-07-29 | 2016-07-29 | A kind of hypoglycemic rhizoma polygonati grape health care wine and its production technology |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106244371B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106867735A (en) * | 2017-02-21 | 2017-06-20 | 张德建 | A kind of donkey-hide gelatin health wine and its processing method |
CN107418859A (en) * | 2017-09-21 | 2017-12-01 | 界首市靳莓果酒有限责任公司 | A kind of strawberry fruit wine acid reduction method |
CN108042739A (en) * | 2018-01-26 | 2018-05-18 | 成都中医药大学附属医院 | It is a kind of to be used to prevent composition of diabetes and its preparation method and application |
CN108102862A (en) * | 2018-01-30 | 2018-06-01 | 贵州省普安县普白珍稀资源开发有限公司 | A kind of gastrodia tuber health wine and preparation method thereof |
CN108517264A (en) * | 2018-03-28 | 2018-09-11 | 沈阳都铎农业科技有限公司 | A kind of fruit wine of nutrition and health care and preparation method thereof |
CN116036194A (en) * | 2018-11-29 | 2023-05-02 | 苏保洲 | Traditional Chinese medicine composition, wine and preparation method and application thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103146559A (en) * | 2013-03-06 | 2013-06-12 | 郑镁钢 | Nutritive health-care wine and preparation method thereof |
CN103224859A (en) * | 2013-03-28 | 2013-07-31 | 陆开云 | Tea rice wine containing leonurus and preparation method thereof |
CN104673573A (en) * | 2015-03-23 | 2015-06-03 | 孙燕霞 | Wine with diabetes prevention and treatment function and preparation method thereof |
CN104825801A (en) * | 2015-05-30 | 2015-08-12 | 天津鑫瑞生物医药科技有限公司 | TCM (traditional Chinese medicine) preparation for preventing and treating cardiovascular and cerebrovascular diseases |
-
2016
- 2016-07-29 CN CN201610619543.0A patent/CN106244371B/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103146559A (en) * | 2013-03-06 | 2013-06-12 | 郑镁钢 | Nutritive health-care wine and preparation method thereof |
CN103224859A (en) * | 2013-03-28 | 2013-07-31 | 陆开云 | Tea rice wine containing leonurus and preparation method thereof |
CN104673573A (en) * | 2015-03-23 | 2015-06-03 | 孙燕霞 | Wine with diabetes prevention and treatment function and preparation method thereof |
CN104825801A (en) * | 2015-05-30 | 2015-08-12 | 天津鑫瑞生物医药科技有限公司 | TCM (traditional Chinese medicine) preparation for preventing and treating cardiovascular and cerebrovascular diseases |
Also Published As
Publication number | Publication date |
---|---|
CN106244371A (en) | 2016-12-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN106244371B (en) | A kind of hypoglycemic rhizoma polygonati grape health care wine and its production technology | |
CN104287013B (en) | A kind of reducing blood lipid function of blood sugar reduction sexual health vinegar beverage and production technology thereof | |
CN102669772B (en) | Traditional Chinese medicine stomach-benefiting health-care beverage | |
CN102827750A (en) | Maca health care liquor for improving organism immunity and sexuality | |
CN103740566B (en) | Rosa roxbunghii medicinal liquor and preparation method thereof | |
CN101085965A (en) | Medlar red date wine | |
CN104719535A (en) | Maca black tea composition capable of improving sub-health status of women and preparation method of maca black tea composition | |
CN102318857B (en) | Liver-protecting alcoholism-relieving plant beverage and preparation method thereof | |
CN104288652B (en) | Chinese medicine composition with hangover-alleviating health-care effect and its preparation method and application | |
CN101168710B (en) | Eucommia bark wine and preparation method thereof | |
CN102113651B (en) | Steamed bread for being eaten by patients who suffer from diabetes and preparation method thereof | |
CN105707598A (en) | Plant drink for dispelling alcohol effects and preparation method thereof | |
CN105360824A (en) | Chinese caterpillar fungus beverage and preparation method thereof | |
CN101085964A (en) | Chrysanthemum wine | |
CN104336174A (en) | Rhodiola rosea and milk vinegar contained green tea health beverage | |
CN102599301B (en) | Covered bowl compound tea beverage | |
CN103082240B (en) | Carrot-ginseng processing method | |
CN106362007A (en) | Traditional Chinese medicine composition containing dendrobium huoshanense and achieving glucose lowering effect and preparation method thereof | |
CN101684445A (en) | Deer horn blood wine and processing method thereof | |
CN109527577A (en) | A kind of composition with sobering up and liver protecting functions | |
CN102827731B (en) | Preparation process of health care liquor | |
CN106350411A (en) | Preparation method of healthcare wine | |
CN105936848A (en) | Preparation method of SOD wine | |
CN1796533A (en) | Health protection wine and preparation method | |
CN104474406A (en) | Health traditional Chinese medicine wine for nourishing yin and moistening lung and preparation method of health traditional Chinese medicine wine |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |