CN103520424A

CN103520424A - Traditional Chinese medicine preparation for treating periodontitis

Info

Publication number: CN103520424A
Application number: CN201310469457.2A
Authority: CN
Inventors: 陈志浩
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-09-25
Filing date: 2013-09-25
Publication date: 2014-01-22

Abstract

A traditional Chinese medicine preparation for treating periodontitis is provided. The traditional Chinese medicine preparation is prepared from radix angelicae pubescentis, divaricate saposhnikovia root, caulis lonicerae, gentiana scabra bunge, rehmannia glutinosa libosch, salivia chinensis, fineleaf schizonepeta herb, rhizoma chuanxiong, glehnia root, asarum herb, radix astragali, and Chinese yam. The traditional Chinese medicine preparation can be clinically used for treating periodontitis.

Description

A kind of Chinese medicine preparation for the treatment of periodontitis

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine preparation for the treatment of periodontitis.

Background technology

Periodontitis is the chronic infectious disease that involves four kinds of periodontal support tissues (gingiva, periodontal membrane, alveolar bone and cementum), often causes the inflammatory destruction of periodontal support tissue.Treatment periodontitis, doctor trained in Western medicine adopts Perorally administrable antimicrobial anti-inflammation drugs and local periodontal surgery and local medicine-feeding etc. more.If alone anti-inflammation drugs, usually can not obtain gratifying effect.Through inventor's long-term practice, draw, Chinese medicine is controlled periodontitis and is had better effect, obtains good effect.

Summary of the invention

The object of the present invention is to provide the Chinese medicine preparation of the treatment periodontitis that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.

The present invention adopts Radix Angelicae Pubescentis, Radix Saposhnikoviae, Caulis Lonicerae, Radix Gentianae, the Radix Rehmanniae, Cortex Moutan, Herba Schizonepetae, Rhizoma Chuanxiong, Radix Glehniae, Herba Asari, the Radix Astragali, Rhizoma Dioscoreae, according to certain compatibility requirement, through being processed into.

Preparing Chinese medicine preparation of the present invention is made by following raw material medicaments: Radix Angelicae Pubescentis 20-40 part, Radix Saposhnikoviae 20-40 part, Caulis Lonicerae 20-30 part, Radix Gentianae 20-30 part, Radix Rehmanniae 20-30 part, Cortex Moutan 20-30 part, Herba Schizonepetae 10-20 part, Rhizoma Chuanxiong 10-20 part, Radix Glehniae 8-15 part, Herba Asari 8-15 part, Radix Astragali 8-15 part, Rhizoma Dioscoreae 8-15 part.

Optimum weight part of Chinese medicine preparation crude drug of the present invention is: 30 parts of Radix Angelicae Pubescentiss, 30 parts of Radix Saposhnikoviaes, 25 parts of Caulis Loniceraes, 25 parts of Radix Gentianaes, 25 parts, the Radix Rehmanniae, 25 parts of Cortex Moutans, 15 parts of Herba Schizonepetae, 15 parts of Rhizoma Chuanxiongs, 10 parts of Radix Glehniaes, 10 parts of Herba Asaris, 10 parts of the Radixs Astragali, 10 parts of Rhizoma Dioscoreaes.

The pharmacological action of Chinese medicine of the present invention is as follows:

Radix Angelicae Pubescentis: pungent, bitter, tepor.Return liver, urinary bladder channel.Wind-damp dispelling, stopping numbness pain, induces sweat.For rheumatism numbness pain, the exterior syndrome that affection of exogenous wind-cold causes etc.

Radix Saposhnikoviae: pungent, sweet, tepor.Return bladder, liver, spleen channel.Deliver loose wind, removing dampness to relieve pain, relieving convulsion, antidiarrheal.For headache due to common cold, rubella pruritus, rheumatic arthralgia, tetanus card etc.

Caulis Lonicerae: sweet, cold.GUIXIN, lung meridian.Heat-clearing and toxic substances removing, dredging collateral.For epidemic febrile disease heating, ulcer sore pain, acute appendicitis, acute mastitis, toxic-heat and blood stasis, rheumatic arthralgia etc.

Radix Gentianae: bitter, cold.Return liver, gallbladder, urinary bladder channel.Heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.For swelling of the vulva pudendal pruritus, leukorrhagia eczema, jaundice dark coloured urine, liver-fire headache, conjunctival congestion are deaf, the hyperpyrexia convulsion due to extreme heat causing wind syndrome, tetany etc.

The Radix Rehmanniae: sweet, bitter, cold.GUIXIN, liver, kidney channel.Clearing away heat and cooling blood, promotes the production of body fluid and moisturizes.For acute calenture, excessive thirst is hindered in Tianjin, the haematemesis of bleeding due to blood-heat, epistaxis, metrorrhagia, aphtha of the mouth and tongue, laryngopharynx swelling and pain, consumptive fever cough, traumatic pain, carbuncle etc.

Cortex Moutan: arduous, cool, be slightly cold.GUIXIN, sweet, kidney, lung meridian.Heat clearing away, promoting blood circulation to remove blood stasis.For the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, tell nosebleed, deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury, rheumatism pyretic arthralgia etc.

Herba Schizonepetae: taste is flat, and warm in nature, faint scent is dense, can dispel the wind detumescence, cooling blood and relieving pain, the loose wind that induces sweat, rash, the skin ulcer that disappears, is diaphoresis, antipyretic.Be mainly used to the tooth diseases such as periodontitis, gingival swelling and pain, gum skin ulcer be hemorrhage.

Rhizoma Chuanxiong: pungent, warm, return liver, gallbladder, heart channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For stagnation of QI and blood, rheumatic arthralgia.

Radix Glehniae: sweet, micro-hardship, be slightly cold, attach to the lung and stomach meridians.Nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.For the lung-heat type cough of deficiency of lung-YIN, the few expectorant of dry cough, deficiency of stomach-YIN or thermal burn stomach-Yin, the thirsty and dry pharynx of deficiency of body fluid etc.

Herba Asari: pungent, temperature, mild toxicity.Return lung, kidney, the heart, liver but, spleen channel.Cold expelling dispels the wind, pain relieving, warming the lung to resolve fluid-retention.For exterior syndrome due to wind-cold, headache, toothache, rheumatic arthralgia etc.

The Radix Astragali: sweet, warm, return lung, spleen channel.Benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening.For diarrhea due to hypofunction of the spleen, wait the card of all Qi and blood deficiencies.

Rhizoma Dioscoreae: sweet, flat.Return spleen, lung, kidney channel.Supplementing QI and nourishing YIN, spleen reinforcing lung kidney, treating spontaneous emission and leukorrhagia.For weakness of the spleen and stomach, the lung weak card of suffering from a deficiency of the kidney, yin asthenia generating intrinsic heat, the diabete of thirsty polydipsia, frequent micturition.

Chinese medicine preparation of the present invention was in 2005 to 2011 the routine patients of clinical observation periodontitis 100, and clinical report is as follows:

1, physical data

In 100 routine patients, age 14-60 year, the course of disease is many at 10 days to 1 year, 38 years old mean age.

2, diagnostic criteria

" traditional Chinese medical science disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:

Gingiva presents inflammation in various degree, as red swelling of gingiva, hemorrhage, gingiva pyorrhea, stippling disappearance etc., periodontal pocket forms, pyorrhea in bag, there is in various degree loosening in tooth, the surrounding of suffering from tooth can be checked through paathogenic factor, as bacterial plaque, tartar, food impaction, traumatic gritting one's teeth, closes and bad dummy etc., and x-ray shows that alveolar bone has absorbing phenomenon in various degree.

3, Therapeutic Method

3.1 prescriptions: Radix Angelicae Pubescentis 30g, Radix Saposhnikoviae 30g, Caulis Lonicerae 25g, Radix Gentianae 25g, Radix Rehmanniae 25g, Cortex Moutan 25g, Herba Schizonepetae 15g, Rhizoma Chuanxiong 15g, Radix Glehniae 10g, Herba Asari 10g, Radix Astragali 10g, Rhizoma Dioscoreae 10g.

3.2 preparation and practical approaches: said medicine routinely technique is made decoction, 1 dose of oral every day, every day 2 times, 7 days is 1 course for the treatment of.

4, therapeutic outcome:

4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":

Recovery from illness: inflammation disappears, gingival swelling and pain disappears, and without inflammatory exudate, periodontal pocket disappears or shoals, and frontal resorption is silent oscillation, and tooth mobility II0 turns I0, and masticatory function is improved, and General Symptoms is removed;

Effective: inflammation disappears, gingival swelling and pain disappears substantially, and substantially without inflammatory exudate, periodontal pocket shoals, and frontal resorption situation is stable, and tooth mobility alleviates, and masticatory function makes moderate progress, and General Symptoms alleviates;

Invalid: symptom, sign slightly alleviate or the person of not being any change.

4.2 results: in 100 routine patients, clinical cure 72 examples (72%), effective 22 examples (22%), invalid 6 examples (6%), total effective rate is 94%.

5, model case

5.1 Cui, female, 29 years old, the red swelling of gingiva of visiting, touch hemorrhage, lower front tooth gingival enlargement, the II degree touching is loosening, has halitosis, large dry stool, red tongue, yellow fur is thick.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and continues to take 3 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.

5.2 Zhangs, man, 44 years old, red swelling of gingiva was congested, and that touches is hemorrhage, odontoseisis, knocking pain, implication heat is smelly, constipation, yellowish or reddish urine.Take medicine of the present invention, 1 dose of every day, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.

The specific embodiment

Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.

Embodiment 1, and a kind of Chinese medicine preparation for the treatment of periodontitis is to be made by Radix Angelicae Pubescentis 20g, Radix Saposhnikoviae 20g, Caulis Lonicerae 20g, Radix Gentianae 20g, Radix Rehmanniae 20g, Cortex Moutan 20g, Herba Schizonepetae 10g, Rhizoma Chuanxiong 10g, Radix Glehniae 8g, Herba Asari 8g, Radix Astragali 8g, Rhizoma Dioscoreae 8g.

Embodiment 2, and a kind of Chinese medicine preparation for the treatment of periodontitis is to be made by Radix Angelicae Pubescentis 30g, Radix Saposhnikoviae 30g, Caulis Lonicerae 25g, Radix Gentianae 25g, Radix Rehmanniae 25g, Cortex Moutan 25g, Herba Schizonepetae 15g, Rhizoma Chuanxiong 15g, Radix Glehniae 10g, Herba Asari 10g, Radix Astragali 10g, Rhizoma Dioscoreae 10g.Embodiment 3, and a kind of Chinese medicine preparation for the treatment of periodontitis is to be made by Radix Angelicae Pubescentis 40g, Radix Saposhnikoviae 40g, Caulis Lonicerae 30g, Radix Gentianae 30g, Radix Rehmanniae 30g, Cortex Moutan 30g, Herba Schizonepetae 20g, Rhizoma Chuanxiong 20g, Radix Glehniae 15g, Herba Asari 15g, Radix Astragali 15g, Rhizoma Dioscoreae 15g.

Claims

1. treat a Chinese medicine preparation for periodontitis, it is characterized in that it is to be made by following raw material medicaments:

Radix Angelicae Pubescentis 20-40 part, Radix Saposhnikoviae 20-40 part, Caulis Lonicerae 20-30 part, Radix Gentianae 20-30 part, Radix Rehmanniae 20-30 part, Cortex Moutan 20-30 part, Herba Schizonepetae 10-20 part, Rhizoma Chuanxiong 10-20 part, Radix Glehniae 8-15 part, Herba Asari 8-15 part, Radix Astragali 8-15 part, Rhizoma Dioscoreae 8-15 part.

2. Chinese medicine preparation according to claim 1, is characterized in that it is to be made by following raw material medicaments:

30 parts of Radix Angelicae Pubescentiss, 30 parts of Radix Saposhnikoviaes, 25 parts of Caulis Loniceraes, 25 parts of Radix Gentianaes, 25 parts, the Radix Rehmanniae, 25 parts of Cortex Moutans, 15 parts of Herba Schizonepetae, 15 parts of Rhizoma Chuanxiongs, 10 parts of Radix Glehniaes, 10 parts of Herba Asaris, 10 parts of the Radixs Astragali, 10 parts of Rhizoma Dioscoreaes.