CN101444565A - Method for preparing seed of lightyellow sophora oral bacteriostasis dropping liquid - Google Patents

Method for preparing seed of lightyellow sophora oral bacteriostasis dropping liquid Download PDF

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Publication number
CN101444565A
CN101444565A CNA2008101917489A CN200810191748A CN101444565A CN 101444565 A CN101444565 A CN 101444565A CN A2008101917489 A CNA2008101917489 A CN A2008101917489A CN 200810191748 A CN200810191748 A CN 200810191748A CN 101444565 A CN101444565 A CN 101444565A
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China
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ethanol
liquid
volatile oil
dropping liquid
kinds
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CNA2008101917489A
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Chinese (zh)
Inventor
谢荣增
吴子申
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INNER MONGOLIA YONGYE BIO-TECH Co Ltd
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INNER MONGOLIA YONGYE BIO-TECH Co Ltd
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Priority to CNA2008101917489A priority Critical patent/CN101444565A/en
Publication of CN101444565A publication Critical patent/CN101444565A/en
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Abstract

The invention discloses a method for preparing a seed of lightyellow sophora oral bacteriostasis dropping liquid, comprising the following steps: clove, green pericarpium zanthoxyli and manchurian wildginger coarse powder are respectively selected, and distilled water is added to extract and separate volatile oil for preserving; creat, giant knotweed coarse powder, gardenia coarse powder are respectively selected, ethanol is added, and liquid is recycled after being extracted twice; the extracted liquid is mixed, filtered and heated by water bath to volatilize the ethanol until extract is formed; the volatile oil is mixed with the extract; borneol, menthol and total matrines are added; after mixing, the ethanol is added and the mixture is allowed to stand; the mixture is filtered and the ethanol is recycled, thereby obtaining a finished product. In the production method, natural botanical remedy extractive is selected, thereby causing no side effects such as drug resistance, residue and the like and no harm to human body. The seed of lightyellow sophora oral bacteriostasis dropping liquid is easy and convenient to use, the dropping liquid is administrated directly on an afflicted part and harmful bacterium reproduction can be restrained; the dropping liquid has good efficacy for various odontalgia nervosa and toothache, decayed tooth and gum swelling and pain which are caused by harmful microbe such as bacteria, virus, pathogen, etc.

Description

The production method of bitter bean bean oral bacteriostasis dropping liquid
Technical field
The present invention relates to a kind of production method of oral bacteriostasis dropping liquid, refer in particular to a kind of production method of bitter bean bean oral bacteriostasis dropping liquid.
Background technology
" having a toothache " is a kind of commonly encountered diseases, though can not cause great influence to human body, the misery of bringing is difficult to stand " having a toothache ".Though the product that has some treatments " to have a toothache " on the present market, great majority all are based on chemical medicine, synthetic drug, and Therapeutic Method also is based on antiinflammatory, antibiotic, infection.In treatment " having a toothache ", also bring a lot of side effect: produce drug resistance to human body as antibiotics to the patient, nerous sedative causes nervous system injury or the like to human body, and the generation of these undesirable elements causes obvious or hidden injury to advocating natural modern today.Yet there are no the preparation of producing treatment " toothache " with natural plants Chinese medicine in the market.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of production method of bitter bean bean oral bacteriostasis dropping liquid, this production method is according to traditional Chinese medicine theory, according to the kind that causes the odontopathy pathogenic bacterium, vegetable drugs such as preferred Herba Sophorae alopecuroidis, Flos Caryophylli, Herba Asari, the application modern biotechnology extracts, extracting and refining forms pure Chinese medicine external drop.
Technical problem of the present invention is solved by following scheme: the production method of bitter bean bean oral bacteriostasis dropping liquid, it is characterized in that: the Flos Caryophylli fine powder, Fructus Zanthoxyli fine powder and the Herba Asari coarse powder that weight such as take by weighing respectively place round-bottomed flask, each adds 6 times of weight distilled water, extract with volatile oil extractor, to be extracted finishing isolated three kinds of volatile oil and preserves; Weight ratio by 1-2:1:1 takes by weighing Herba Andrographis, Fructus Gardeniae coarse powder, Rhizoma Polygoni Cuspidati coarse powder respectively, place round-bottomed flask, each adds 8 times of weight concentrations is 80% ethanol, extract withdrawal liquid after 1-2 hours, respectively add 6 times of weight concentrations again and be 80% ethanol extraction withdrawal liquid after 1-2 hours, each mixes front and back extracted twice liquid, filter, and flings to ethanol with heating in water bath, to three kinds of extractum shapes preservations; Above three kinds of volatile oil are mixed with three kinds of extractum, add Borneolum Syntheticum, Mentholum, Radix Sophorae Flavescentis total alkaloids again, it is that 95% ethanol leaves standstill 48 hours after-filtration and reclaims ethanol that three kinds of volatile oil, three kinds of extractum, Borneolum Syntheticum, Mentholum, Radix Sophorae Flavescentis total alkaloids are added 8 times of weight concentrations after with the weight ratio mix homogeneously of 1:3-4:0.4-0.6:0.4-0.6:1, at last bitter bean bean oral bacteriostasis dropping liquid finished product.
Advantage of the present invention is: the Chinese medicine and pharmacy theory thinks that " having a toothache " is because due to the flaming up of stomach-fire, interior living excess-fire." have a toothache " though for due to the endogenous cause of ill, the disease that occurs is that we select the preferably selection of " endogenous cause of ill external treatment " for use, makes the effective ingredient sick institute that goes directly, and heat-clearing and toxic substances removing can directly effectively be inhibited " having a toothache " due to the exopathogen.This production method is selected Flos Caryophylli, Herba Asari, Fructus Gardeniae strengthening vital QI to eliminate pathogenic factors for use, dispeling the wind relieves the pain, and Fructus Zanthoxyli has obvious inhibitory action to the antibacterial that causes dental caries; With Herba Andrographis heat-clearing and toxic substances removing, annealing detumescence, bacillus pyocyaneus, Hemolytic streptococcus all there is in various degree inhibitory action; Borneolum Syntheticum, Mentholum antiphlogistic antibacterial; Radix Sophorae Flavescentis total alkaloids also has stronger inhibitory action to staphylococcus aureus, Candida albicans, escherichia coli etc.The prescription of this production method can both effectively suppress " having a toothache " that the various causes of disease cause by effects such as strengthening vital QI to eliminate pathogenic factors, heat-clearing and toxic substances removing, anti-inflammation detumescences, thereby effectively treatment " having a toothache " is removed misery to the patient.
The present invention also has following advantage: 1, the medicine selected for use of this production method is the natural medicinal plants extract, does not produce drug resistance, side effect such as residual, to human body without any injury.
2, bitter bean bean oral bacteriostasis dropping liquid natural green, have no side effect, easy to use need not taking orally directly from the affected part administration, reduced in the medicine body consumption in the fortuneization process and scattered and disappeared, suppress harmful bacterium and breed, be ideal pharmaceutical dosage form.
Diseases such as 3, bitter bean bean oral bacteriostasis dropping liquid is applicable to that various nervous toothache and antibacterial, virus, pathogenic bacterium harmful microorganism cause has a toothache, dental caries, gingival swelling and pain.
During use, medicinal liquid directly dropped in suffer from the teeth space place, drip affected part or every day 2-3 time continuously every the period, 2-4 drips at every turn.Medicine liquid droplet is gargled with clear water suffering from tooth after the 15-20 of place minute.This drop is that pure plant extracts makes, and tries not medicinal liquid is swallowed, and it is not unhealthful to swallow accidentally.After finishing, tighten bottle cap, put dry lucifuge place.The careful usefulness of ethanol allergy sufferers.
Description of drawings
Accompanying drawing is bitter bean bean oral bacteriostasis dropping liquid technological process of production figure
The specific embodiment
1, takes by weighing the Flos Caryophylli grinding and place round-bottomed flask, add 6 times of weight distilled water, heating jacket, volatile oil extractor, condensing tube are installed, extract then, treat that volatile oil extracts finish (no longer including volatile oil proposes), isolates volatile oil and preserves.
2, take by weighing Fructus Zanthoxyli and place round-bottomed flask, add 6 times of weight distilled water, heating jacket, volatile oil extractor, condensing tube are installed, extract then, treat that the volatile oil extraction finishes, and isolates volatile oil and preserves.
3, take by weighing the Herba Asari coarse powder, place round-bottomed flask, add 6 times of weight distilled water, installation heating jacket, volatile oil extractor, condensing tube extract.Treat that the volatile oil extraction finishes, and separates volatile oil and preserves.
4, take by weighing Herba Andrographis, place round-bottomed flask, add 8 times of weight of 80% ethanol, heating jacket, condensing tube are installed, extracted withdrawal liquid 2 hours; And add 6 times of weight of 80% ethanol again and extracted 1.5 hours, the back withdrawal liquid that finishes, with front and back extracted twice liquid mixing, filtration, and heating in water bath flings to ethanol, preserves to the extractum shape.
5, take by weighing the Rhizoma Polygoni Cuspidati coarse powder, place the 5000ml round-bottomed flask, add 8 times of weight of 80% ethanol, heating jacket, condensing tube extraction 2 hours is installed, withdrawal liquid; And add 6 times of weight of 80% ethanol again and extracted 1.5 hours, the back withdrawal liquid that finishes, with front and back extracted twice liquid mixing, filtration, and heating in water bath flings to ethanol, preserves to the extractum shape.
6, take by weighing the Fructus Gardeniae coarse powder, place round-bottomed flask, add 8 times of weight of 80% ethanol, heating jacket, condensing tube extraction 2 hours is installed, withdrawal liquid; And add 6 times of weight of 80% ethanol again and extracted 1.5 hours, the back withdrawal liquid that finishes, with front and back extracted twice liquid mixing, filtration, and heating in water bath flings to ethanol, preserves to the extractum shape.
7, will mix with creat extract 25kg, Rhizoma Polygoni Cuspidati coarse powder extractum 15kg, Fructus Gardeniae coarse powder extractum 15kg with above-mentioned Flos Caryophylli volatile oil 5kg, Fructus Zanthoxyli volatile oil 5kg, Herba Asari coarse powder volatile oil 5kg, and add Borneolum Syntheticum 8kg, Mentholum 7kg, Radix Sophorae Flavescentis total alkaloids 15kg, add 800kg concentration 95% ethanol behind the mix homogeneously and leave standstill 48 hours after-filtration and reclaim ethanol, at last bitter bean bean oral bacteriostasis dropping liquid finished product.

Claims (1)

1, the production method of bitter bean bean oral bacteriostasis dropping liquid, it is characterized in that: the Flos Caryophylli fine powder, Fructus Zanthoxyli fine powder and the Herba Asari coarse powder that weight such as take by weighing respectively place round-bottomed flask, and each adds 6 times of weight distilled water, extracts with volatile oil extractor, to be extracted finishing isolated three kinds of volatile oil and preserves; Weight ratio by 1-2:1:1 takes by weighing Herba Andrographis, Fructus Gardeniae coarse powder, Rhizoma Polygoni Cuspidati coarse powder respectively, place round-bottomed flask, each adds 8 times of weight concentrations is 80% ethanol, extract withdrawal liquid after 1-2 hours, respectively add 6 times of weight concentrations again and be 80% ethanol extraction withdrawal liquid after 1-2 hours, each mixes front and back extracted twice liquid, filter, and flings to ethanol with heating in water bath, to three kinds of extractum shapes preservations; Above three kinds of volatile oil are mixed with three kinds of extractum, add Borneolum Syntheticum, Mentholum, Radix Sophorae Flavescentis total alkaloids again, it is that 95% ethanol leaves standstill 48 hours after-filtration and reclaims ethanol that three kinds of volatile oil, three kinds of extractum, Borneolum Syntheticum, Mentholum, Radix Sophorae Flavescentis total alkaloids are added 8 times of weight concentrations after with the weight ratio mix homogeneously of 1:3-4:0.4-0.6:0.4-0.6:1, at last bitter bean bean oral bacteriostasis dropping liquid finished product.
CNA2008101917489A 2008-12-31 2008-12-31 Method for preparing seed of lightyellow sophora oral bacteriostasis dropping liquid Pending CN101444565A (en)

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CNA2008101917489A CN101444565A (en) 2008-12-31 2008-12-31 Method for preparing seed of lightyellow sophora oral bacteriostasis dropping liquid

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102600287A (en) * 2012-03-22 2012-07-25 李翠荣 Compound medicine for treating toothache
CN110464656A (en) * 2019-08-29 2019-11-19 西安医学院 A kind of dental filling resin material and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102600287A (en) * 2012-03-22 2012-07-25 李翠荣 Compound medicine for treating toothache
CN110464656A (en) * 2019-08-29 2019-11-19 西安医学院 A kind of dental filling resin material and preparation method thereof
CN110464656B (en) * 2019-08-29 2022-07-05 西安医学院 Resin material for dental prosthesis and preparation method thereof

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Open date: 20090603