CN111544466B - Traditional Chinese medicine composition and application thereof in preparation of medicine for preventing neocoronary pneumonia - Google Patents
Traditional Chinese medicine composition and application thereof in preparation of medicine for preventing neocoronary pneumonia Download PDFInfo
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Abstract
The invention relates to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition and application thereof in preparation of a medicine for preventing neocoronary pneumonia. The composition comprises the following raw materials: astragalus root, white atractylodes rhizome, eupatorium fortunei, glehnia root, male fern rhizome, honeysuckle, forsythia and great burdock achene. The composition has effects in strengthening qi, strengthening body resistance, invigorating spleen, eliminating dampness, clearing away heat and toxic materials, and can be used for preventing new coronavirus infection and fever, cough, asthma, anorexia, etc. caused by various toxic heat fire syndromes.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition and application thereof in preparation of a medicine for preventing neocoronary pneumonia.
Background
The new type of coronavirus pneumonia (hereinafter referred to as new type pneumonia) is different from common pneumonia, which is small in infectivity and usually caused by incomplete treatment after exogenous pathogenic factors, and is usually diagnosed as wind-heat invading lung or fire-toxin accumulating lung in the field of traditional Chinese medicine. If lung abscess is caused by pneumonia, it is called "pulmonary abscess". The new coronary pneumonia belongs to the category of 'grumpy' in the traditional Chinese medicine, mainly invades lung meridian of hand taiyin and large intestine meridian of hand yangming, causes lung to lose qi and descend and dampness to block middle energizer, has the basic pathogenesis characteristics of 'dampness', is easy to block qi activity and invades middle energizer spleen and stomach due to the pathogenic attribute of 'dampness'. Therefore, the traditional Chinese medicine scheme for preventing common pneumonia is not suitable for preventing new coronary pneumonia.
The vaccine is one of the most important measures for preventing and controlling infectious diseases, but the vaccine preparation period is long, the problems of effectiveness and safety are also faced, the vaccine cannot be obtained in the early stage of epidemic situation, and the newly emerged virus cannot be widely used before the spread of the virus, so that no vaccine for the new coronary pneumonia exists at present.
Disclosure of Invention
Aiming at the technical problems that the new coronavirus is also infectious in the latent period and no available vaccine or prevention scheme is available, the invention provides a traditional Chinese medicine composition.
The invention also provides application of the composition in preparing a medicament for preventing new coronary pneumonia.
In order to achieve the purpose of the invention, the embodiment of the invention adopts the following technical scheme:
a traditional Chinese medicine composition comprises the following raw materials in parts by weight: 13-17 parts of astragalus membranaceus, 7-11 parts of bighead atractylodes rhizome, 8-12 parts of fortune eupatorium herb, 8-12 parts of radix glehniae, 4-8 parts of rhizoma dryopteris crassirhizomae, 7-11 parts of honeysuckle, 8-12 parts of fructus forsythiae and 4-8 parts of great burdock achene.
The traditional Chinese medicine composition provided by the invention comprises the following components:
the astragalus membranaceus is sweet in taste and slightly warm in nature, enters lung and spleen channels, has the effects of tonifying qi and raising yang, tonifying qi and consolidating superficial resistance, inducing diuresis to alleviate edema, promoting production of body fluid and nourishing blood, activating stagnancy and removing obstruction of qi, detoxifying and expelling pus, healing sores and promoting granulation.
The rhizoma atractylodis macrocephalae is bitter and sweet in taste and warm in nature, enters spleen and stomach channels, strengthens spleen and qi, eliminates dampness and induces diuresis, and stops sweating, and can be used for treating spleen qi weakness, transportation and transformation failure, endogenous water dampness such as poor appetite, loose stool, abdominal distension and diarrhea and the like.
Pei lan is pungent in flavor and neutral in nature, and can enter spleen, stomach and lung meridians, fragrant in flavor to resolve dampness, activate spleen and stimulate appetite, release exterior syndrome and relieve summer-heat, so it is indicated for damp-heat syndrome of spleen meridian.
The radix glehniae is sweet and slightly bitter in taste and slightly cold in nature, enters lung and stomach channels, nourishes yin to clear away the lung-heat, benefits the stomach and generates body fluid, and can tonify lung yin, clear lung heat, tonify middle-jiao and qi, protect spleen and stomach and maintain body immunity in the traditional Chinese medicine composition.
Honeysuckle flower is sweet in taste and cold in nature, enters lung, heart and stomach meridians, clears away heat and toxic materials, and disperses wind and heat. Being sweet, cold and light in nature, fragrant and loose, it is indicated for affection of exogenous wind-heat and warm diseases, and it can be used for pulmonary abscess caused by excessive heat-toxicity after infection of new corona virus.
Fructus forsythiae is bitter in taste and slightly cold in nature, enters lung, heart and small intestine channels, and has the effects of clearing away heat and toxic materials, relieving swelling, resolving masses and dispelling wind and heat. It is bitter and cold with strong actions of clearing and descending, excelling in clearing and purging heart fire, and indicated for high fever, restlessness and coma due to invasion of heat into pericardium after infection by new coronavirus.
Rhizoma Dryopteris Crassirhizomatis is bitter in taste, slightly cold in nature and slightly toxic, enters liver and stomach meridians, clears away heat and toxic materials, relieves swelling and stagnation, dispels wind and heat, and is good at clearing heart fire, relieving sore and eliminating carbuncle and swelling.
Burdock, fructus Arctii, with pungent and bitter taste and cold nature, enters lung and stomach meridians, disperses wind and heat, ventilates lung and promotes eruption, dispels phlegm and relieves sore throat, detoxifies and subdues swelling, and ascending and descending of this herb has the property of clearing and descending, which is superior to dispersing lung and dispelling phlegm, and clearing and relieving sore throat.
The whole formula takes the astragalus root as a monarch drug, the eupatorium, the bighead atractylodes rhizome and the radix glehniae are used for strengthening the spleen and stomach, regulating qi and eliminating dampness, and are ministerial drugs, and the astragalus root and the radix glehniae are used together, so that the traditional Chinese medicine can nourish lung yin, tonify lung qi, tonify qi and strengthen superficies, nourish yin and clear lung-heat, and the lung qi tonifying functions of the astragalus root and the radix glehniae have the synergistic effect of replenishing vital qi. The honeysuckle, the weeping forsythia and the great burdock achene are used together to treat early symptoms of a new crown patient, such as wind-heat type common cold, fever at the beginning of warm diseases, sore throat and the like. Rhizoma Dryopteris Crassirhizomatis and fructus Arctii have the effects of clearing away heat, promoting blood circulation, removing toxic substances, and promoting vital qi to expel pathogenic factors out of body, and are used as adjuvant drugs. The whole formula has the effects of strengthening qi, benefiting vital qi, invigorating spleen, eliminating dampness, clearing heat and detoxicating, and can promote vital qi of organism, prevent new coronavirus infection and symptoms such as fever, cough, asthma, anorexia, etc. caused by lung yin deficiency, lung qi deficiency and various heat-toxin fire syndromes. Compared with the similar medicines, the composition has relatively small toxic and side effects and is safe to use.
Preferably, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 14-16 parts of astragalus membranaceus, 8-10 parts of bighead atractylodes rhizome, 9-11 parts of fortune eupatorium herb, 9-11 parts of radix glehniae, 5-7 parts of rhizoma dryopteris crassirhizomae, 8-10 parts of honeysuckle, 9-11 parts of fructus forsythiae and 5-7 parts of great burdock achene.
Preferably, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15 parts of astragalus membranaceus, 9 parts of bighead atractylodes rhizome, 10 parts of eupatorium fortunei, 10 parts of radix glehniae, 6 parts of rhizoma dryopteris crassirhizomae, 9 parts of honeysuckle, 10 parts of fructus forsythiae and 6 parts of burdock.
In the practical use of the traditional Chinese medicine, 1g of the traditional Chinese medicine is used as each dose, and 1-2 doses are used every day according to the prevention requirement.
The embodiment of the invention also provides application of the traditional Chinese medicine composition in preparing a medicine for preventing new coronary pneumonia. The composition can strengthen healthy qi, and can prevent the patients from being attacked even if the users feel exogenous pathogenic factors, so the composition can be used for preparing the medicine for preventing the new coronary pneumonia.
The embodiment of the invention also provides a medicine for preventing new coronary pneumonia, and the medicine comprises the composition.
Preferably, the preparation method of the medicine comprises the following steps: weighing the raw materials according to the raw material proportion in the traditional Chinese medicine composition, decocting and extracting the raw materials with water, collecting the obtained extracting solution, and concentrating. The obtained concentrated solution can be further sterilized and dried according to actual requirements.
The preparation method is simple to operate and is suitable for small-batch production and large-production-scale production. The composition can be extracted and concentrated by the preparation method, and has reduced dosage and convenient administration. The obtained concentrated solution can be further made into oral dosage forms such as oral liquid, tablet, granule, capsule, powder, etc.
Preferably, the water decoction extraction method is to decoct the raw materials with water which is 6-8 times of the weight of the raw materials for 2-3 times, and each time lasts for 1-1.5 hours.
Preferably, the water decoction extraction method comprises the steps of firstly decocting the raw materials for 1.5 hours by using water with the weight 8 times that of the raw materials, and then decocting the raw materials for 1 hour by using water with the weight 6 times that of the raw materials.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Examples
The embodiment of the invention provides a traditional Chinese medicine composition, and in each embodiment, raw materials in each dose are shown in table 1 (unit: g).
TABLE 1 raw material composition of the Chinese medicinal composition in each example
The embodiment of the invention also provides a medicine for preventing neocoronary pneumonia, which is prepared by weighing the raw materials according to the formula of each traditional Chinese medicine composition in the embodiment 1-5, decocting the raw materials for 2-3 times by using water with the weight 6-8 times that of the raw materials, decocting for 1-1.5 hours each time, collecting the obtained extracting solution, concentrating and sterilizing. The raw material composition of each agent and the parameter conditions in the preparation method in each example are shown in table 2.
TABLE 2 raw material composition and preparation parameters for the examples
Examples of effects
This effect example provides the use effect of the above-described drug for preventing neocoronary pneumonia.
Medical staff who are engaged in relevant work such as diagnosis, nursing and treatment of patients with new coronary pneumonia in the fifth hospital of Shijiazhuang city of 12 months to 2020 in 2019 take one dose of the medicine for preventing new coronary pneumonia provided by embodiment 6 of the invention every day. 850 medical staff (including medical staff who treat and nurse new coronary pneumonia severe patients) are randomly selected from the medical staff for infection condition statistics, and the result shows that no infection exists.
The results show that the traditional Chinese medicine composition provided by the invention can effectively prevent the infection of the new coronavirus.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents or improvements made within the spirit and principle of the present invention should be included in the scope of the present invention.
Claims (8)
1. A traditional Chinese medicine composition for preventing Xinguan pneumonia is characterized by being prepared from the following raw materials in parts by weight: 13-17 parts of astragalus membranaceus, 7-11 parts of bighead atractylodes rhizome, 8-12 parts of fortune eupatorium herb, 8-12 parts of radix glehniae, 4-8 parts of rhizoma dryopteris crassirhizomae, 7-11 parts of honeysuckle, 8-12 parts of fructus forsythiae and 4-8 parts of great burdock achene.
2. The traditional Chinese medicine composition as claimed in claim 1, which is prepared from the following raw materials in parts by weight: 14-16 parts of astragalus membranaceus, 8-10 parts of bighead atractylodes rhizome, 9-11 parts of fortune eupatorium herb, 9-11 parts of radix glehniae, 5-7 parts of rhizoma dryopteris crassirhizomae, 8-10 parts of honeysuckle, 9-11 parts of fructus forsythiae and 5-7 parts of great burdock achene.
3. The traditional Chinese medicine composition as claimed in claim 2, which is prepared from the following raw materials in parts by weight: 15 parts of astragalus membranaceus, 9 parts of bighead atractylodes rhizome, 10 parts of eupatorium fortunei, 10 parts of radix glehniae, 6 parts of rhizoma dryopteris crassirhizomae, 9 parts of honeysuckle, 10 parts of fructus forsythiae and 6 parts of great burdock achene.
4. The use of the Chinese medicinal composition of any one of claims 1-3 in the preparation of a medicament for preventing neocoronary pneumonia.
5. A medicine for preventing neocoronary pneumonia, which is characterized by comprising the traditional Chinese medicine composition of any one of claims 1-3.
6. The medicament for preventing the neocoronary pneumonia according to claim 5, wherein the preparation method of the medicament comprises the following steps: weighing the raw materials according to the mixture ratio of the raw materials in the traditional Chinese medicine composition, decocting the raw materials with water for extraction, collecting the obtained extract, and concentrating.
7. The medicine for preventing neocoronary pneumonia according to claim 6, wherein the water decoction extraction method is to decoct the raw materials with water of 6-8 times of the weight of the raw materials for 2-3 times, each time for 1-1.5 hours.
8. The medicine for preventing the new coronary pneumonia according to claim 7, wherein the water decoction extraction method comprises the steps of decocting the raw materials for 1.5 hours by using water with the weight 8 times that of the raw materials, and then decocting the raw materials for 1 hour by using water with the weight 6 times that of the raw materials.
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