CN101199765B - Medicament for treating stomach disease - Google Patents
Medicament for treating stomach disease Download PDFInfo
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- CN101199765B CN101199765B CN2006101657463A CN200610165746A CN101199765B CN 101199765 B CN101199765 B CN 101199765B CN 2006101657463 A CN2006101657463 A CN 2006101657463A CN 200610165746 A CN200610165746 A CN 200610165746A CN 101199765 B CN101199765 B CN 101199765B
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Abstract
Disclosed is a medicine for treating gastritis. The invention is prepared by the raw materials with the following weight proportions: Taibaimi(bulb of Notholirion hyacinthinum) 2-20, Radix Astragali 8-35, Rhizoma Dioscoreae Bulbiferae 5-30 and Rhizoma Corydalis 5-25. The preparation process is that the Rhizoma Corydalis is dried, crushed and is filtered through a 100mesh sieve to form powder 1 for later use; the Taibaimi(bulb of Notholirion hyacinthinum), Radix Astragali and Rhizoma Dioscoreae Bulbiferae are extracted for two times in water 5-20 times of the total weight of the three, and the extraction each time costs 1.5 hours; the extractives are mixed, condensed and dried to form powder 2; the dregs of the decoctions are further extracted in hydrophilic organic solvent, the rate of the dregs and the organic solvent is 1: 4-20, the dregs are dissolved for 1-8 hours in the solvent under the temperature between 20 DEG C - 120 DEG C and are extracted for two times with each time 1-5 hours, then the extractives are cooled under the room temperature and filtered, the residues are filtered out, the filtered liquid is condensed and the organic solvent is recovered, and then the condensed liquid is dried under 80 degrees to form a solid product 3; the products 1, 2 and 3 are combined together to be taken as the effective ingredients and then mixed evenly and prepared into granules which are encapsulated. The invention mainly treats acute and chronic gastritis, superficial gastritis, atrophic gastritis, gastric and duodenal ulcer, early stage of gastric cancer and esophagus cancer.
Description
1 technical field
The present invention relates to a kind of medicine stomach power open capsule for the treatment of gastropathy, be particularly suitable for treating acute or chronic gastritis, superficial gastritis, atrophic gastritis, gastric and duodenal ulcers; Alleviate stomachache, flatulence; For gastric cancer, esophageal carcinoma prevention and therapeutical effect are arranged also.
2 background technologies
Present technique is based on the basis to year clinical observation research surplus the research of Bullus Notholirionis Bulbuliferi effective ingredient and effect and early stage 10, finally determine the prescription composition and the consumption of stomach power open capsule, and determined the preparation technology of stomach power open capsule in conjunction with the characteristics of its pharmacology, toxicity, pharmacodynamics and pharmacokinetics.
3 summary of the invention
Main contents of the present invention are that the prescription of stomach power open capsule is formed and preparation technology.
This product of treatment mechanism is mainly killed by phenolic acids, steroid alkaloid and glycoside composition synergism thereof or is suppressed helicobacter pylori, treats acute slow gastritis, superficial gastritis, atrophic gastritis, stomach and duodenal ulcer; Alleviate stomachache, flatulence; For gastric cancer, esophageal carcinoma prevention and therapeutical effect are arranged also.
This product of theoretical foundation mainly is made up of Chinese medicines such as Bullus Notholirionis Bulbuliferi, Antenoron filiforme herb, the Radix Astragali, Rhizoma Corydalis.Bullus Notholirionis Bulbuliferi is a monarch drug in the side, belong to too from mountain special product Chinese medicine, has the chest stuffiness relieving promoting the circulation of QI, the preventing or arresting vomiting cough-relieving, effects such as stomach-tonifying and pain alleviating, in recent years study its phenolic acids that contains, steroid alkaloid and glycoside composition synergism thereof and kill or suppress helicobacter pylori, treat acute slow gastritis, superficial gastritis, atrophic gastritis, stomach and duodenal ulcer; Alleviate stomachache, flatulence; For gastric cancer, esophageal carcinoma prevention and therapeutical effect are arranged also; Antenoron filiforme herb is the Mount Taibai rare Chinese medicine also, have be good for the stomach and in, the sharp purgation function of heat clearing away is ministerial drug in the side; The Radix Astragali in the side and the unit adjuvant drug of acting like a bully, wherein the Radix Astragali has the function of strengthening QI of middle-JIAO, promoting the circulation of QI to relieve pain, invigorating the stomach and promoting digestion, and Rhizoma Corydalis mainly has the effect of promoting the circulation of QI to relieve pain.Ministerial drug in the side can increase the effect that the monarch drug Bullus Notholirionis Bulbuliferi is good for the stomach, and adjuvant drug Radix Astragali strengthening QI of middle-JIAO can increase the power of gastrointestinal peristalsis, and Rhizoma Corydalis then increases analgesic effect, and the synergy of a few like this flavor Chinese medicine has the function with stomach and alleviating pain, depressed liver-energy dispersing and QI regulating.
Design
A kind of Chinese medicine preparation stomach power open capsule is made by the material medicine of following weight ratio
Bullus Notholirionis Bulbuliferi 2-20, Radix Astragali 8-35, Antenoron filiforme herb 5-30, Rhizoma Corydalis 5-25.
The present invention is rapid-action, determined curative effect, cure mainly anxious slow gastritis, superficial gastritis, atrophic gastritis,, diseases such as gastric and duodenal ulcers, stomachache, flatulence.For early gastric cancer prevention and therapeutical effect are arranged also.
Its technology is: the Rhizoma Corydalis drying, pulverize, and cross 100 mesh sieves, powder 1 is standby.Bullus Notholirionis Bulbuliferi, the Radix Astragali and Antenoron filiforme herb add twice of the water extraction that 5-20 doubly measures, each 1-5 hour, merge extractive liquid, filters, and concentrates drying, get pressed powder 2, above three medicine medicinal residues are further extracted with hydrophilic organic solvent: medicinal residues: the weight ratio of hydrophilic organic solvent=1: 4～20, to dissolve 1～8 hour, temperature is 20 ℃～120 ℃, extract twice, each 1-5 hour, be cooled to room temperature, filter, remove filtering residue, filtrate is concentrated and reclaims organic solvent,, obtain solid product 3 dry below 80 ℃.Merge product 1,2 and product 3 and obtain effective component extracts.Mixing is made microgranule on granulator again, incapsulate then.
Advantage and this product of effect are pure Chinese medicinal preparation, have no side effect, and raw material is than horn of plenty, and preparation technology is simple, and clinical efficacy is fairly obvious, are the first-selected Chinese patent medicine of the various gastropathy of treatment in the present domestic like product, and its clinical cure rate reaches more than 98%.
Clinical observation is summed up stomach power open capsule to 1996 and year has been carried out since the clinical observation, observes 16～80 patients about 2000 routine patients altogether, about 1200 examples of patient male, about 800 examples of female patients over surplus in the of ten year.Produce effects 1986 people wherein, obvious effective rate reaches more than 99%, cures 1783 people, and cure rate reaches more than 79%.
4 specific embodiments:
The composition that stomach power is logical: Bullus Notholirionis Bulbuliferi 10g, Radix Astragali 30g, Antenoron filiforme herb 15g, Rhizoma Corydalis 15g.
The preparation technology that stomach power is logical: the Rhizoma Corydalis drying, pulverize, cross 100 mesh sieves, powder 1 is standby.Bullus Notholirionis Bulbuliferi, the Radix Astragali and Antenoron filiforme herb add the water extraction twice of 10 times of amounts, and each 2 hours, merge extractive liquid, filtered, concentrate, drying gets pressed powder 2, above three medicine medicinal residues are further extracted with hydrophilic organic solvent: medicinal residues: 80% alcoholic acid weight ratio=1: 7, to dissolve 2 hours, temperature is 70-80 ℃, extract twice, each 2 hours, be cooled to room temperature, filter, remove filtering residue, filtrate is concentrated and reclaims organic solvent,, obtain solid product 3 dry below 80 ℃.Merge product 1,2 and product 3 and obtain effective component extracts.Mixing is made microgranule on granulator again, incapsulate then.
Function cures mainly and stomach and alleviating pain, depressed liver-energy dispersing and QI regulating.Cure mainly acute gastritis, chronic superficial gastritis, atrophic gastritis, diseases such as stomach and duodenal ulcer, stomachache, flatulence.For early gastric cancer, liver cirrhosis etc. prevention and therapeutical effect are also arranged.
Usage and dosage is oral: three times on the one, and each 1-2 grain, warm water takes.
Pungent, the greasy product of taboo period in a medicine taboo food.
Claims (2)
1. medicine for the treatment of gastropathy is characterized in that being made by the material medicine of following weight ratio:
Bullus Notholirionis Bulbuliferi 2-20, Radix Astragali 8-35, Antenoron filiforme herb 5-30, Rhizoma Corydalis 5-25.
2. according to the preparation technology of the treatment gastropathy medicine of claim 1 record: the Rhizoma Corydalis drying, pulverize, cross 100 mesh sieves; powder 1 is standby, Bullus Notholirionis Bulbuliferi; the Radix Astragali and Antenoron filiforme herb add the water extraction twice that 5-20 doubly measures, each 1-5 hour; merge extractive liquid, filters, and concentrates drying; get pressed powder 2; above three herbal medicine medicinal residues are further extracted with hydrophilic organic solvent: medicinal residues: the weight ratio of hydrophilic organic solvent=1: 4～20, to dissolve 1～8 hour, temperature is 20 ℃～120 ℃; extract twice; each 1-5 hour, be cooled to room temperature, filter; remove filtering residue; filtrate is concentrated and reclaims organic solvent,, obtain solid product 3 dry below 80 ℃; merge product 1; 2 and product 3 obtain effective component extracts, mixing is made microgranule on granulator again; incapsulate then.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006101657463A CN101199765B (en) | 2006-12-15 | 2006-12-15 | Medicament for treating stomach disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006101657463A CN101199765B (en) | 2006-12-15 | 2006-12-15 | Medicament for treating stomach disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101199765A CN101199765A (en) | 2008-06-18 |
| CN101199765B true CN101199765B (en) | 2010-11-10 |
Family
ID=39515248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2006101657463A Expired - Fee Related CN101199765B (en) | 2006-12-15 | 2006-12-15 | Medicament for treating stomach disease |
Country Status (1)
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| CN (1) | CN101199765B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106138814A (en) * | 2016-08-04 | 2016-11-23 | 王贵 | A kind of for Chinese medicine composition treating chronic gastropathy and preparation method thereof |
| CN110368462A (en) * | 2019-08-30 | 2019-10-25 | 鱼涛 | Treat the Chinese medicine composition of atrophic gastritis and its preparation method of capsule |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1204526A (en) * | 1998-07-09 | 1999-01-13 | 庄树桐 | 'Huweiling' capsule- for protecting stomach |
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2006
- 2006-12-15 CN CN2006101657463A patent/CN101199765B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1204526A (en) * | 1998-07-09 | 1999-01-13 | 庄树桐 | 'Huweiling' capsule- for protecting stomach |
Non-Patent Citations (1)
| Title |
|---|
| 曾升海等.复方朱砂七汤治疗慢性胃炎180例.陕西中医.1995,16(7),295. * |
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| CN101199765A (en) | 2008-06-18 |
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Granted publication date: 20101110 Termination date: 20121215 |