CN102579902B - Chinese medicine composition for curing sicca syndrome and preparation method thereof - Google Patents
Chinese medicine composition for curing sicca syndrome and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese medicine composition for curing sicca syndrome and a preparation method thereof. The Chinese medicine composition for curing the sicca syndrome mainly comprises the following components by weight: 1200-3000 parts of plaster stone, 200-450 parts of honeysuckle, 70-180 parts of the root barks of the peony trees, 70-180 parts of Indian iphigenia bulb, 200-450 parts of radix gentianae macrophyllae, 2000-450 parts of hedyotis diffusa, 200-450 parts of radix scrophulariae, 70-180 parts of radix puerariae, 200-450 parts of arisaema heterophyllum, 200-450 parts of coix Seeds, 200-450 parts of dried rehamnnia roots, 70-180 parts of radix paeoniae rubra, 200-450 parts of radix astragali and 200-450 parts of Japanese honeysuckle stems. The Chinese medicine composition for curing the sicca syndrome has the effects of nourishing yin, cooling blood, clearing heat, promoting diuresis, tonifying qi and dredging collaterals, and suitable for curing pain caused by dry eyes, dry mouths, dry skins, dry joints and the like.
Description
Technical field
The present invention relates to drug world, particularly relate to a kind of Chinese medicine composition for the treatment of dry syndrome and preparation method thereof.
Background technology
Dry syndrome is a kind of chronic auto-immune connective tissue disease, can betide any age, but in the majority with middle aged sequela, and women accounts for more than 90%, and generation and the heredity of this disease, endocrine, viral infection may be relevant, and the definite cause of disease is still not clear.At present both at home and abroad modern medicine is without effective medicine, can only anti symptom treatment, uses artificial tearful eyes, xerostomia artificial saliva etc. as eye is dry.Patient's burst shows as that eye is dry, mouth and nose are dry, severe one adacrya, without saliva, enter that drinkable water send, some women patient vagina drying, painful exception.Pathological changes often involves lung, liver, kidney, gastrointestinal, skin, joint and lymph etc., Chang Jifa rheumatoid arthritis, lupus erythematosus, polymyositis, arteritis nodosa etc., simultaneously can malignant lymphoma and the allergic vasculitis such as concurrent chronic active hepatitis, skein cell tumor.
Sjogren syndrome is a global disease, and age of onset is mostly the person in middle and old age of 40 ~ 60 years old, and children's is less.Owing to lacking unified diagnostic criteria so far, so the prevalence of this disease is very inaccurate.Generally be estimated as 0.1% ~ 0.7%.In the U.S., the sickness rate of sjogren syndrome is only second to rheumatoid arthritis.For many years, primary disease is always stranger in China, until 1980 just arouse attention later, and observes it, studies.Domestic warp finds the investigation of more than ten thousand crowds, and this sick prevalence is 0.29% ~ 0.77%, and the sickness rate being not less than rheumatoid arthritis 0.3% ~ 0.4% in the prevalence of China's primary disease is described.But, in the prior art, also this disease is not had to medicine or the Therapeutic Method of curative effect.
Therefore, prior art has yet to be improved and developed.
Summary of the invention
In view of above-mentioned the deficiencies in the prior art, the object of the present invention is to provide a kind of Chinese medicine composition for the treatment of dry syndrome and preparation method thereof, be intended to solve the incurable problem of dry syndrome in prior art.
Technical scheme of the present invention is as follows:
Treat a Chinese medicine composition for dry syndrome, wherein, count by weight, mainly composed of the following components:
Gypsum Fibrosum 1200-3000 part Flos Lonicerae 200-450 part
Cortex Moutan 70-180 part Pseudobulbus Cremastrae Seu Pleiones 70-180 part
Radix Gentianae Macrophyllae 200-450 part Herba Hedyotidis Diffusae 2000-450 part
Radix Scrophulariae 200-450 part Radix Puerariae 70-180 part
Rhizoma Arisaematis 200-450 part Semen Coicis 200-450 part
Radix Rehmanniae 200-450 part Radix Paeoniae Rubra 70-180 part
Radix Astragali 200-450 part Caulis Lonicerae 200-450 part.
The Chinese medicine composition of described treatment dry syndrome, wherein, the Chinese medicine composition of described treatment dry syndrome is granule.
A preparation method for the Chinese medicine composition of above-mentioned treatment dry syndrome, wherein, comprises the following steps:
Get Gypsum Fibrosum, Rhizoma Arisaematis adds 2-7 times of soak by water 1-5 time, each 1-4 hour, being concentrated into density is 1.0-2.0;
Get residue 12 taste medical material and add 2-7 times of water gaging, decoct 1-5 time, each 1-4 hour, collecting decoction, filter, be concentrated into density 1.0-2.0, add ethanol and stir evenly that to be adjusted to concentration be 50-90%, leave standstill, get supernatant and filter, reclaim under reduced pressure;
The filtered solution of 12 taste medical materials and Gypsum Fibrosum, Rhizoma Arisaematis decocting liquid are merged, dry, pulverize into fine powder;
Fine powder is mixed homogeneously by 1:2-5 with dextrin, with 50-90% ethanol for binding agent is granulated, 50-90 DEG C of drying.
Beneficial effect: the Chinese medicine composition that the present invention is used for the treatment of dry syndrome has effect of phencyclidine, clearing away heat-damp and promoting diuresis, activating qi and collateral, is applicable to that treatment eye is dry, the dried pain of xerostomia, xerosis cutis and joint etc.Through clinical verification for many years, safe and reliable, determined curative effect, simultaneously in conjunction with modern Chinese drug preparation technique, has produced taking convenience, portable Chinese medicine preparation.
Detailed description of the invention
The invention provides a kind of Chinese medicine composition for the treatment of dry syndrome and preparation method thereof, for making object of the present invention, technical scheme and effect clearly, clearly, the present invention is described in more detail below.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
The Chinese medicine composition for the treatment of dry syndrome provided by the present invention is the pure compound Chinese medicinal preparation with replenishing body fluid and clearing away heat pathogen effect, by Gypsum Fibrosum, Rhizoma Arisaematis, Flos Lonicerae, Cortex Moutan, Semen Coicis, Radix Rehmanniae, the prescriptions such as Herba Hedyotidis Diffusae, there is effect of phencyclidine, clearing away heat-damp and promoting diuresis, activating qi and collateral, be applicable to that treatment eye is dry, the dried pain of xerostomia, xerosis cutis and joint etc.
Chinese medicine is at phencyclidine, clearing away heat-damp and promoting diuresis, there is long history activating qi and collateral aspect, the Chinese medicine composition for the treatment of dry syndrome provided by the present invention is through clinical verification for many years, safe and reliable, determined curative effect, simultaneously in conjunction with modern Chinese drug preparation technique, has produced taking convenience, portable new medicine preparation.
The Chinese medicine composition of described treatment dry syndrome, counts by weight, mainly composed of the following components:
Gypsum Fibrosum 1200-3000 part Flos Lonicerae 200-450 part
Cortex Moutan 70-180 part Pseudobulbus Cremastrae Seu Pleiones 70-180 part
Radix Gentianae Macrophyllae 200-450 part Herba Hedyotidis Diffusae 2000-450 part
Radix Scrophulariae 200-450 part Radix Puerariae 70-180 part
Rhizoma Arisaematis 200-450 part Semen Coicis 200-450 part
Radix Rehmanniae 200-450 part Radix Paeoniae Rubra 70-180 part
Radix Astragali 200-450 part Caulis Lonicerae 200-450 part.
The Chinese medicine composition of described treatment dry syndrome preferably makes granule, is replenishing body fluid and clearing away heat pathogen granule.
Also provide the Chinese medicine composition for the treatment of dry syndrome to make the preparation method of granule in the present invention, specifically comprise the following steps:
Get Gypsum Fibrosum, Rhizoma Arisaematis adds 2-7 times of soak by water 1-5 time, each 1-4 hour, being concentrated into density is 1.0-2.0(50-90 DEG C);
Remain 12 taste medical materials and add 2-7 times of water gaging, decoct 1-5 time, each 1-4 hour, collecting decoction, filter, be concentrated into density 1.0-2.0(50-90 DEG C), add ethanol and stir evenly that to be adjusted to concentration be 50-90%, leave standstill, get supernatant and filter, decompression recycling ethanol is extremely without alcohol taste;
The filtered solution of 12 taste medical materials and Gypsum Fibrosum, Rhizoma Arisaematis decocting liquid are merged, dry, pulverize into fine powder;
Mixed homogeneously by 1:2-5 with dextrin by fine powder, with 50-90% ethanol for binding agent is granulated, 50-90 DEG C of drying, makes 500-2500g, to obtain final product.
Gypsum Fibrosum: sweet, pungent, Great Cold.Attach to the lung and stomach meridians.There is clearing away heat-fire, the function that relieving restlessness is quenched the thirst.For fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, headache, toothache etc.
Flos Lonicerae: sweet in the mouth is cold in nature, returns lung, the heart, stomach warp.Energy heat-clearing and toxic substances removing, wind-heat dissipating.Be used for the treatment of epidemic febrile disease heating, warm blood fulminant dysentery carbuncle furuncle, sore throat, erysipelas, anemopyretic cold.External all have inhibitory action to various bacteria (Bacillus typhi, escherichia coli, Bacillus proteus, bacillus pyocyaneus, bordetella pertussis, vibrio cholera and staphylococcus, streptococcus, Diplococcus pneumoniae, meningococcus etc.), especially to typhoid fever and Salmonella paratyphi effect stronger.Some inhibitory action is had in vitro to Bacillus tuberculosis.
Cortex Moutan: Cortex Moutan bitter in the mouth, pungent, cold nature.GUIXIN, liver, kidney channel.There is clearing away heat and cooling blood, the function of promoting blood circulation to remove blood stasis.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters grieved grade for disease.Blood pressure lowering, antibacterial, calm, hypnosis, analgesia, convulsion, to bring down a fever and antiinflammatory.Experiment shows, hypotensive effect Cortex Moutan water decoction is the strongest, and paeonol takes second place, and goes the water decoction of paeonol the most weak; Cortex Moutan is remarkable to the antibacterial action such as dysentery bacterium, Bacillus typhi, the strongest at pH7.0-7.6 sterilizing power, all has inhibitory action for Common Pathogenic dermatophytes; Mouse peritoneal injection or oral paeonol, have calmness, hypnosis, analgesic activity; Paeonol has inhibitory action to rat hindlimb foot edema.
Pseudobulbus Cremastrae Seu Pleiones: sweet, micro-pungent, cool.Return liver, spleen channel.Tool heat-clearing and toxic substances removing, the function of dissipating phlegm and resolving masses.Radix Gentianae Macrophyllae: Radix Gentianae Macrophyllae bitter in the mouth, pungent, property is put down; Enter liver, stomach, gallbladder meridian.Tool expelling wind and removing dampness, and blood relaxing muscles and tendons, the function of clearing away heat and promoting diuresis; For rheumatic arthralgia, the contracture of muscle arteries and veins, jaundice, has blood in stool, the diseases such as dysuria.Decoct and ethanol-soluble extractives, heavy dose of to the experimental heating of rat, there is refrigeration function; Neutral alcohol preserved material can alleviate arthroncus degree to rat albumen arthritis, and accelerates it and disappear; The blood pressure of anesthetized animal can be reduced; All inhibitory action is had in vitro to anthrax bacillus, staphylococcus aureus, vibrio cholera, Bacillus proteus etc.Radix Gentianae Macrophyllae infusion has inhibitory action in various degree to various skin fungus in vitro.Gentianin after purifying has the effects such as antiinflammatory, calmness, blood pressure lowering, blood glucose increasing, shock, and its mechanism of action is relevant with the secretion level affecting epinephrine and acetylcholine.
Herba Hedyotidis Diffusae: micro-hardship, micro-sweet, is slightly cold.GUIXIN, liver, spleen channel.Tool heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, the function of inducing diuresis to remove edema.
Radix Scrophulariae: Radix Scrophulariae cold nature is sweet in the mouth, hardship, salty.Return lung, stomach, kidney channel.There is effect of removing heat from blood YIN nourishing, eliminating fire and detoxication.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, the diseases such as pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.Radix Puerariae: sweet, pungent, cool.Return spleen, stomach warp.There is expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, rash, the function of yang invigorating antidiarrheal.
Rhizoma Arisaematis: bitter, pungent, warm; Poisonous.Return lung, liver, spleen channel.There is drying dampness to eliminate phlegm, expelling wind and relieving convulsion, the function of mass dissipating and swelling eliminating.
Semen Coicis: nature and flavor with return through: sweet, light, cool.Return spleen, stomach, lung meridian.Function with cure mainly: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, heat clearing away are arranged dense.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, acute appendicitis, verruca plana.
Radix Rehmanniae: sweet, bitter, cold.GUIXIN, liver, kidney channel.There is clearing away heat and promoting production of body fluid, removing heat from blood, the function of hemostasis.
Radix Paeoniae Rubra: Radix Paeoniae Rubra bitter in the mouth, is slightly cold.Return Liver Channel.There is clearing away heat and cooling blood, the function of dissipating blood stasis.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, traumatic injury, the diseases such as carbuncle skin infection.
The Radix Astragali: slightly warm in nature, sweet in the mouth.Return lung, spleen channel.There is invigorating QI to consolidate the body surface resistance, hidroschesis, poison holding, granulation promoting, effect of diuresis detumescent.Cure mainly deficient qi and blood, refreshing tired lack of appetite, chronic diarrhea proctoptosis, exterior deficiency is from apogee sweating, and blood deficiency wind-engaging, numbness of the skin, skin sore is not burst or burst and do not hold back for a long time and the card such as hydroderma.Process by QI invigorating, life consolidating superficial resistance, holder skin ulcer.Caulis Lonicerae: sweet, cold.Attach to the lung and stomach meridians.There is heat-clearing and toxic substances removing, the function of dispelling wind dredging collateral.
Clinical application effect: the granule product in the present invention drops into clinic trial in Chongwen, Beijing Ying Ping rheumatism hospital and Changchun Ying Ping rheumatism hospital, evaluates the typical dry syndrome patients of 72 example, method: the principle adopting random, non-blind, contrast.Treatment group 36 example, oral replenishing body fluid and clearing away heat pathogen granule 3 times/d, each 1 bag, 28d is a course for the treatment of, totally 3 courses for the treatment of; Matched group 36 example, gives oxychloroquine treatment.Result: clinical symptoms and sign that replenishing body fluid and clearing away heat pathogen granule is improving patient (P < 0.01) evident in efficacy, significant curative effect (P < 0.01) is had for increase patient saliva amount, have obvious curative effects (P < 0.01) to hemocytes increasing, and comprehensive therapeutic effect is better than matched group.In safety, two groups all have good safety.
Embodiment 1
Gypsum Fibrosum 1200 portions of Flos Loniceraes 200 parts
Cortex Moutan 70 parts of Pseudobulbus Cremastrae Seu Pleioness 70 parts
Radix Gentianae Macrophyllae 200 parts of Herba Hedyotidis Diffusaes 2000 parts
Radix Scrophulariae 200 parts of Radix Puerariaes 70 parts
Rhizoma Arisaematis 200 parts of Semen Coiciss 200 parts
Radix Rehmanniae 200 parts of Radix Paeoniae Rubra 70 parts
The Radix Astragali 200 parts of Caulis Loniceraes 200 parts.
Preparation technology: get Gypsum Fibrosum, Rhizoma Arisaematis adds 2-7 times of soak by water 1-5 time, each 1-4 hour, being concentrated into density is 1.0-2.0(50-90 DEG C); Remain 12 taste medical materials and add 2-7 times of water gaging, decoct 1-5 time, each 1-4 hour, collecting decoction, filter, be concentrated into density 1.0-2.0(50-90 DEG C), add ethanol and stir evenly that to be adjusted to concentration be 50-90%, leave standstill, get supernatant and filter, decompression recycling ethanol is extremely without alcohol taste; The filtered solution of 12 taste medical materials and Gypsum Fibrosum, Rhizoma Arisaematis decocting liquid are merged, dry, pulverize into fine powder; Mixed homogeneously by 1:2-5 with dextrin by fine powder, with 50-90% ethanol for binding agent is granulated, 50-90 DEG C of drying, makes 500-2500g, to obtain final product.
The described a kind of Chinese medicine granules for the treatment of dry syndrome adopting this proportioning to make, has 8 people to take, every day three times in clinical, each bag, warm water delivery service.Taking and within 28 days, reach that eye is dry, xerostomia, xerosis cutis symptom alleviate 2 examples, take that 56 days eyes are dry, xerostomia, xerosis cutis symptom alleviate 2 examples, having 4 examples still treating by changing proportioning after 56 days.
Model case: Mrs Ji, 41 years old
General joint repeated relapsing pain was there is without inducement in patient before 4 years, and do with interruption heating, xerostomia, eye, once went to a doctor at local hospital, chemical examination RF++, ESR20mm/h, SSA(+), SSB(+), diagnosis " rheumatoid arthritis, sjogren syndrome ", takes immunosuppressant and hormone therapy, aggravation.My institute medical in 2009, diagnosis is the same, gives oral embodiment of the present invention Chinese medicine granules and the Comprehensive Treatment 28 days of being admitted to hospital, heavy time light during joint symptoms, but mouth Dry eye alleviates.
Embodiment 2
Gypsum Fibrosum 1500 portions of Flos Loniceraes 300 parts
Cortex Moutan 100 parts of Pseudobulbus Cremastrae Seu Pleioness 100 parts
Radix Gentianae Macrophyllae 300 parts of Herba Hedyotidis Diffusaes 300 parts
Radix Scrophulariae 300 parts of Radix Puerariaes 100 parts
Rhizoma Arisaematis 300 parts of Semen Coiciss 300 parts
Radix Rehmanniae 300 parts of Radix Paeoniae Rubra 100 parts
The Radix Astragali 300 parts of Caulis Loniceraes 300 parts.
Preparation technology: get Gypsum Fibrosum, Rhizoma Arisaematis adds 2-7 times of soak by water 1-5 time, each 1-4 hour, being concentrated into density is 1.0-2.0(50-90 DEG C); Remain 12 taste medical materials and add 2-7 times of water gaging, decoct 1-5 time, each 1-4 hour, collecting decoction, filter, be concentrated into density 1.0-2.0(50-90 DEG C), add ethanol and stir evenly that to be adjusted to concentration be 50-90%, leave standstill, get supernatant and filter, decompression recycling ethanol is extremely without alcohol taste; The filtered solution of 12 taste medical materials and Gypsum Fibrosum, Rhizoma Arisaematis decocting liquid are merged, dry, pulverize into fine powder; Mixed homogeneously by 1:2-5 with dextrin by fine powder, with 50-90% ethanol for binding agent is granulated, 50-90 DEG C of drying, makes 500-2500g, to obtain final product.
The described a kind of Chinese medicine granules for the treatment of dry syndrome adopting this proportioning to make, has 8 people to take, every day three times in clinical, each bag, warm water delivery service.Take and within 28 days, reach that eye is dry, xerostomia, xerosis cutis symptom alleviate 4 examples, take that 56 days eyes are dry, xerostomia, xerosis cutis symptom alleviate 4 examples.
Model case: Ms Zhang 50 years old
There is finger-joint pain because of 2003 without obvious inducement in this trouble, gradually stiff for morning to general joint pain companion, rear symptom alleviates voluntarily, does not take notice of.Thereafter the state of an illness again and again, started interruption and take strong bone capsule (being suspected to have hormonal components), disease amelioration before 5 years.Then occur that xerostomia, eye are dry, and time swallow dryness food difficulty.JIUYUE in 2009 2 days is to our hospital, chemical examination: rheumatoid factor ++++, erythrocyte sedimentation rate 115mm/h, anti-" O " 200
u, RO-52(+) and anti-SSA(+), routine blood test HGB92g/L.X-ray film shows both hands, two knee joint, both shoulders, two ankle arthritis; Lumbar vertebra hyperosteogeny, be diagnosed as " rheumatoid arthritis, sjogren syndrome ", give oral embodiment of the present invention Chinese medicine granules and promoting the circulation of blood liquid light quantum intraoperative autologous blood transfusion of being admitted to hospital, calcium treat, exempt from the Comprehensive Treatments such as treatment, joint symptoms obviously alleviates, and mouth Dry eye disappears, joint motion freely.
Embodiment 3
Gypsum Fibrosum 3000 portions of Flos Loniceraes 450 parts
Cortex Moutan 180 parts of Pseudobulbus Cremastrae Seu Pleioness 180 parts
Radix Gentianae Macrophyllae 450 parts of Herba Hedyotidis Diffusaes 450 parts
Radix Scrophulariae 450 parts of Radix Puerariaes 180 parts
Rhizoma Arisaematis 450 parts of Semen Coiciss 450 parts
Radix Rehmanniae 450 parts of Radix Paeoniae Rubra 180 parts
The Radix Astragali 450 parts of Caulis Loniceraes 450 parts
Preparation technology: get Gypsum Fibrosum, Rhizoma Arisaematis adds 2-7 times of soak by water 1-5 time, each 1-4 hour, being concentrated into density is 1.0-2.0(50-90 DEG C); Remain 12 taste medical materials and add 2-7 times of water gaging, decoct 1-5 time, each 1-4 hour, collecting decoction, filter, be concentrated into density 1.0-2.0(50-90 DEG C), add ethanol and stir evenly that to be adjusted to concentration be 50-90%, leave standstill, get supernatant and filter, decompression recycling ethanol is extremely without alcohol taste; The filtered solution of 12 taste medical materials and Gypsum Fibrosum, Rhizoma Arisaematis decocting liquid are merged, dry, pulverize into fine powder; Mixed homogeneously by 1:2-5 with dextrin by fine powder, with 50-90% ethanol for binding agent is granulated, 50-90 DEG C of drying, makes 500-2500g, to obtain final product.
The described a kind of Chinese medicine granules for the treatment of dry syndrome adopting this proportioning to make, has 8 people to take, every day three times in clinical, each bag, warm water delivery service.Take and within 28 days, reach that eye is dry, xerostomia, xerosis cutis symptom alleviate 5 examples, take that 56 days eyes are dry, xerostomia, xerosis cutis symptom alleviate 3 examples.
Model case: Mrs Jia 50 years old
There is double knee joint pain because catching a cold, swelling because of in February, 2008 both hands carpal tunnel syndrome Post operation in this trouble, then whole body arthralgia, and with extremities joint symmetry pain for work, swelling, morning is stiff, and xerostomia, eye are dry.Be in hospital 3 months, Orally decoctions etc. had no and were clearly better to college of traditional Chinese medicine's rheumatism hospital diagnosis " rheumatoid arthritis, sjogren syndrome " in January, 2009.On March 17th, 2009, the medical college of traditional Chinese medicine, chemically examined: RF-, ESR57mm/h, ASO200
u.Hematuria is conventional, anti-SSA+, anti-SSB+, anti-dsDNA-and, 26 are to our hospital, and diagnosis is the same, and give oral embodiment of the present invention Chinese medicine granules and to walk abreast Comprehensive Treatment, arthralgia alleviates, and mouth Dry eye is alleviated.
Should be understood that, application of the present invention is not limited to above-mentioned citing, for those of ordinary skills, can be improved according to the above description or convert, and all these improve and convert the protection domain that all should belong to claims of the present invention.
Claims (3)
1. treat a Chinese medicine composition for dry syndrome, it is characterized in that, count by weight, raw material is composed of the following components:
Gypsum Fibrosum 1200-3000 part Flos Lonicerae 200-450 part
Cortex Moutan 70-180 part Pseudobulbus Cremastrae Seu Pleiones 70-180 part
Radix Gentianae Macrophyllae 200-450 part Herba Hedyotidis Diffusae 2000-450 part
Radix Scrophulariae 200-450 part Radix Puerariae 70-180 part
Rhizoma Arisaematis 200-450 part Semen Coicis 200-450 part
Radix Rehmanniae 200-450 part Radix Paeoniae Rubra 70-180 part
Radix Astragali 200-450 part Caulis Lonicerae 200-450 part;
The Chinese medicine composition of described treatment dry syndrome has the effect of replenishing body fluid and clearing away heat pathogen.
2. the Chinese medicine composition for the treatment of dry syndrome according to claim 1, is characterized in that, the Chinese medicine composition of described treatment dry syndrome is granule.
3. a preparation method for the Chinese medicine composition for the treatment of dry syndrome as claimed in claim 2, is characterized in that, comprise the following steps:
Get Gypsum Fibrosum, Rhizoma Arisaematis adds 2-7 times of soak by water 1-5 time, each 1-4 hour, being concentrated into relative density is 1.0-2.0;
Get residue 12 taste medical material and add 2-7 times of water gaging, decoct 1-5 time, each 1-4 hour, collecting decoction, filter, be concentrated into relative density 1.0-2.0, add ethanol and stir evenly that to be adjusted to concentration be 50-90%, leave standstill, get supernatant and filter, reclaim under reduced pressure;
The filtered solution of 12 taste medical materials and Gypsum Fibrosum, Rhizoma Arisaematis decocting liquid are merged, dry, pulverize into fine powder;
Fine powder is mixed homogeneously by 1:2-5 with dextrin, with 50-90% ethanol for binding agent is granulated, 50-90 DEG C of drying.
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| CN102935177B (en) * | 2012-12-08 | 2014-08-13 | 新乡医学院第一附属医院 | Traditional Chinese medicine composition for treating sjogren syndrome as well as preparation method and application thereof |
| CN103263620B (en) * | 2013-06-09 | 2014-12-31 | 张玉华 | Traditional Chinese medicine preparation for treating sjoegren syndrome and preparation method thereof |
| CN103585352B (en) * | 2013-11-25 | 2015-07-15 | 重庆市中药研究院 | Traditional Chinese medicinal composition for yin nourishing and pathogenic fire reducing, and its application |
| CN104306721A (en) * | 2014-11-07 | 2015-01-28 | 朱海燕 | Traditional Chinese medicine composition for sjogren syndrome as well as preparation method and application |
| CN107669889B (en) * | 2017-09-28 | 2020-08-04 | 北京中医药大学 | Pharmaceutical composition for treating sicca syndrome and preparation method and application thereof |
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| CN101121013A (en) * | 2006-08-07 | 2008-02-13 | 郭占友 | Medicine for treating intractable oral cavity ulcer, Baiser's disease and sjogren syndrome and manufacturing method |
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