CN102579902A - Chinese medicine composition for curing sicca syndrome and preparation method thereof - Google Patents
Chinese medicine composition for curing sicca syndrome and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese medicine composition for curing sicca syndrome and a preparation method thereof. The Chinese medicine composition for curing the sicca syndrome mainly comprises the following components by weight: 1200-3000 parts of plaster stone, 200-450 parts of honeysuckle, 70-180 parts of the root barks of the peony trees, 70-180 parts of Indian iphigenia bulb, 200-450 parts of radix gentianae macrophyllae, 2000-450 parts of hedyotis diffusa, 200-450 parts of radix scrophulariae, 70-180 parts of radix puerariae, 200-450 parts of arisaema heterophyllum, 200-450 parts of coix Seeds, 200-450 parts of dried rehamnnia roots, 70-180 parts of radix paeoniae rubra, 200-450 parts of radix astragali and 200-450 parts of Japanese honeysuckle stems. The Chinese medicine composition for curing the sicca syndrome has the effects of nourishing yin, cooling blood, clearing heat, promoting diuresis, tonifying qi and dredging collaterals, and suitable for curing pain caused by dry eyes, dry mouths, dry skins, dry joints and the like.
Description
Technical field
The present invention relates to drug world, relate in particular to a kind of Chinese medicine composition of treating dry syndrome and preparation method thereof.
Background technology
Dry syndrome is a kind of chronic LADA connective tissue disease, can betide any age, but in the majority with middle aged sequela, the women accounts for more than 90%, the generation of this disease and heredity, and endocrine, viral infection maybe be relevant, and the definite cause of disease is still not clear.At present both at home and abroad modern medicine does not have effective medicine, can only anti symptom treatment, and to do like eye and to use artificial tearful eyes, xerostomia is with artificial saliva etc.Patient burst shows as that eye is done, mouth and nose are dry, weight person adacrya, no saliva, feed water send, part female patient vagina drying, and misery unusually.Pathological changes is often involved lung, liver, kidney, gastrointestinal, skin, joint and lymph etc.; Chang Jifa rheumatoid arthritis, lupus erythematosus, polymyositis, arteritis nodosa etc. simultaneously can concurrent chronic active hepatitiss, malignant lymphoma and allergic vasculitis such as skein cell tumor.
Sjogren syndrome is a global disease, and age of onset is 40 ~ 60 years old person in middle and old age mostly, and children's is less.Owing to lack unified diagnostic criteria so far, so prevalence that should disease is very inaccurate.Generally be estimated as 0.1% ~ 0.7%.In the U.S., the sickness rate of sjogren syndrome is only second to rheumatoid arthritis.For many years, primary disease is stranger always in China, just aroused attention later on until 1980, and it is observed, studies.Domestic warp finds that to crowd's surplus ten thousand investigation this disease prevalence is 0.29% ~ 0.77%, and the sickness rate that is not less than rheumatoid arthritis 0.3% ~ 0.4% in the prevalence of China's primary disease is described.But, in the prior art, also this disease is not had the medicine or the Therapeutic Method of curative effect.
Therefore, prior art awaits to improve and development.
Summary of the invention
Deficiency in view of above-mentioned prior art the object of the present invention is to provide a kind of Chinese medicine composition of treating dry syndrome and preparation method thereof, is intended to solve the incurable problem of dry syndrome in the prior art.
Technical scheme of the present invention is following:
A kind of Chinese medicine composition of treating dry syndrome wherein, is counted by weight, and is mainly composed of the following components:
Gypsum Fibrosum 1200-3000 part Flos Lonicerae 200-450 part
Cortex Moutan 70-180 part Pseudobulbus Cremastrae Seu Pleiones 70-180 part
Radix Gentianae Macrophyllae 200-450 part Herba Hedyotidis Diffusae 2000-450 part
Radix Scrophulariae 200-450 part Radix Puerariae 70-180 part
Rhizoma Arisaematis 200-450 part Semen Coicis 200-450 part
Radix Rehmanniae 200-450 part Radix Paeoniae Rubra 70-180 part
Radix Astragali 200-450 part Caulis Lonicerae 200-450 part.
The Chinese medicine composition of described treatment dry syndrome, wherein, the Chinese medicine composition of said treatment dry syndrome is a granule.
A kind of method for preparing of Chinese medicine composition of above-mentioned treatment dry syndrome wherein, may further comprise the steps:
Get Gypsum Fibrosum, Rhizoma Arisaematis adds 2-7 times of decocting and boils 1-5 time, each 1-4 hour, being concentrated into density was 1.0-2.0;
Get residue 12 flavor medical materials and add 2-7 times of water gaging, decocts 1-5 time, each 1-4 hour, collecting decoction, filtration is concentrated into density 1.0-2.0, adds ethanol and stirs that to be adjusted to concentration be 50-90%, leaves standstill, and gets the supernatant filtration, reclaim under reduced pressure;
Filtered solution and Gypsum Fibrosum, the Rhizoma Arisaematis decocting liquid of 12 flavor medical materials are merged, and drying is ground into fine powder;
Fine powder and dextrin are pressed the 1:2-5 mix homogeneously, are that binding agent is granulated 50-90 ℃ of drying with 50-90% ethanol.
Beneficial effect: the Chinese medicine composition that the present invention is used to treat dry syndrome has the effect of YIN nourishing removing heat from blood, clearing away heat-damp and promoting diuresis, activating qi and collateral, is applicable to that the treatment eye is done, xerostomia, the dried pain of xerosis cutis and joint etc.Through clinical verification for many years, safe and reliable, determined curative effect combines modern Chinese drug preparation technique simultaneously, has produced taking convenience, portable Chinese medicine preparation.
The specific embodiment
The present invention provides a kind of Chinese medicine composition of treating dry syndrome and preparation method thereof, and is clearer, clear and definite for making the object of the invention, technical scheme and effect, below to further explain of the present invention.Should be appreciated that specific embodiment described herein only in order to explanation the present invention, and be not used in qualification the present invention.
The Chinese medicine composition of treatment dry syndrome provided by the present invention is the pure compound Chinese medicinal preparation with replenishing body fluid and clearing away heat pathogen effect; Be by Gypsum Fibrosum, Rhizoma Arisaematis, Flos Lonicerae, herd Cortex Moutan, Semen Coicis, Radix Rehmanniae; Prescriptions such as Herba Hedyotidis Diffusae; Effect with YIN nourishing removing heat from blood, clearing away heat-damp and promoting diuresis, activating qi and collateral is applicable to that treatment eye is done, xerostomia, the dried pain of xerosis cutis and joint etc.
Chinese medicine is at the YIN nourishing removing heat from blood; Clearing away heat-damp and promoting diuresis, there is long history the activating qi and collateral aspect, and the Chinese medicine composition of treatment dry syndrome provided by the present invention is through for many years clinical verification; Safe and reliable; Determined curative effect combines modern Chinese drug preparation technique simultaneously, has produced taking convenience, portable new medicine preparation.
The Chinese medicine composition of said treatment dry syndrome is counted by weight, and is mainly composed of the following components:
Gypsum Fibrosum 1200-3000 part Flos Lonicerae 200-450 part
Cortex Moutan 70-180 part Pseudobulbus Cremastrae Seu Pleiones 70-180 part
Radix Gentianae Macrophyllae 200-450 part Herba Hedyotidis Diffusae 2000-450 part
Radix Scrophulariae 200-450 part Radix Puerariae 70-180 part
Rhizoma Arisaematis 200-450 part Semen Coicis 200-450 part
Radix Rehmanniae 200-450 part Radix Paeoniae Rubra 70-180 part
Radix Astragali 200-450 part Caulis Lonicerae 200-450 part.
The Chinese medicine composition of said treatment dry syndrome is preferably processes granule, is the replenishing body fluid and clearing away heat pathogen granule.
Also provide the Chinese medicine composition of treating dry syndrome to process the method for preparing of granule among the present invention, specifically may further comprise the steps:
Get Gypsum Fibrosum, Rhizoma Arisaematis adds 2-7 times of decocting and boils 1-5 time, each 1-4 hour, being concentrated into density was 1.0-2.0 (50-90 ℃);
Remain 12 flavor medical materials and add 2-7 times of water gaging, decoct 1-5 time, each 1-4 hour, collecting decoction; Filter, be concentrated into density 1.0-2.0 (50-90 ℃), add ethanol and stir that to be adjusted to concentration be 50-90%; Leave standstill, get supernatant and filter, decompression recycling ethanol is to there not being the alcohol flavor;
Filtered solution and Gypsum Fibrosum, the Rhizoma Arisaematis decocting liquid of 12 flavor medical materials are merged, and drying is ground into fine powder;
Fine powder and dextrin are pressed the 1:2-5 mix homogeneously, are that binding agent is granulated with 50-90% ethanol, and 50-90 ℃ of drying processed 500-2500g, promptly gets.
Gypsum Fibrosum: sweet, hot, Great Cold.Attach to the lung and stomach meridians.Has clearing away heat-fire, the function that relieving restlessness is quenched the thirst.Be used for fever caused by exogenous pathogenic factors, hyperpyrexia excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, headache, toothache etc.
Flos Lonicerae: sweet in the mouth is cold in nature, returns lung, the heart, stomach warp.The ability heat-clearing and toxic substances removing, wind-heat dissipating.Be used to treat the epidemic febrile disease heating, warm blood fulminant dysentery carbuncle furuncle, sore throat, erysipelas, anemopyretic cold.External all have inhibitory action to various bacteria (Bacillus typhi, escherichia coli, Bacillus proteus, bacillus pyocyaneus, bordetella pertussis, vibrio cholera and staphylococcus, streptococcus, Diplococcus pneumoniae, meningococcus etc.), especially stronger to typhoid fever and Salmonella paratyphi effect.External the Bacillus tuberculosis there is some inhibitory action.
Cortex Moutan: Cortex Moutan bitter in the mouth, suffering, cold nature.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the function of promoting blood circulation to remove blood stasis.Be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, the amenorrhea dysmenorrhea, carbuncle sore tumefacting virus falls diseases such as pouncing on the pain of injury.Blood pressure lowering, antibiotic, calm, hypnosis, analgesia, convulsion, bring down a fever and antiinflammatory.Experiment shows that hypotensive effect Cortex Moutan water decoction is the strongest, and paeonol takes second place, the water decoction that removes paeonol a little less than; Cortex Moutan is remarkable to antibacterial actions such as dysentery bacterium, Bacillus typhi, and is the strongest at the pH7.0-7.6 sterilizing power, for common pathogenic dermatophytes inhibitory action arranged all; Mouse peritoneal injection or oral paeonol have calmness, hypnosis, analgesic activity; Paeonol has inhibitory action to rat hindlimb foot edema.
Pseudobulbus Cremastrae Seu Pleiones: sweet, little suffering, cold.Return liver, spleen channel.Tool is used heat-clearing and toxic substances removing, the function of dissipating phlegm and resolving masses.Radix Gentianae Macrophyllae: Radix Gentianae Macrophyllae bitter in the mouth, suffering, property is flat; Go into liver, stomach, gallbladder meridian.Tool expelling wind and removing dampness and blood Shujin, the function of clearing away heat and promoting diuresis; Be used for rheumatic arthralgia, the contracture of muscle arteries and veins, jaundice is had blood in stool, diseases such as dysuria.Decoct and ethanol-soluble extractives, heavy dose of to the experimental heating of rat, refrigeration function is arranged; The neutral alcohol preserved material can alleviate the arthroncus degree to the rat albumen arthritis, and quickens it and disappear; Can reduce the blood pressure of anesthetized animal; External anthrax bacillus, staphylococcus aureus, vibrio cholera, Bacillus proteus etc. all there is inhibitory action.The Radix Gentianae Macrophyllae infusion has inhibitory action in various degree to the various skin fungus in vitro.Gentianin after purifying has effects such as antiinflammatory, calmness, blood pressure lowering, blood glucose increasing, shock, and its mechanism of action is relevant with the secretion level that influences epinephrine and acetylcholine.
Herba Hedyotidis Diffusae: little hardship, little sweet is slightly cold.GUIXIN, liver, spleen channel.Tool is used heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, the function of inducing diuresis to remove edema.
Radix Scrophulariae: Radix Scrophulariae cold nature, sweet in the mouth, hardship, salty.Return lung, stomach, kidney channel.Effect with removing heat from blood YIN nourishing, eliminating fire and detoxication.Be used for consumption of YIN caused by febrile disease, the crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, diseases such as pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.Radix Puerariae: sweet, hot, cool.Return spleen, stomach warp.Have expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, rash, the function of yang invigorating antidiarrheal.
Rhizoma Arisaematis: bitter, hot, warm; Poisonous.Return lung, liver, spleen channel.Have drying dampness to eliminate phlegm, expelling wind and relieving convulsion, the function of mass dissipating and swelling eliminating.
Semen Coicis: nature and flavor with return through: sweet, light, cold.Return spleen, stomach, lung meridian.Function with cure mainly: row is dense for spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, heat clearing away.Be used for edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, acute appendicitis, verruca plana.
Radix Rehmanniae: sweet, bitter, cold.GUIXIN, liver, kidney channel.Has clearing away heat and promoting production of body fluid, removing heat from blood, the function of hemostasis.
Radix Paeoniae Rubra: the Radix Paeoniae Rubra bitter in the mouth is slightly cold.Return Liver Channel.Has clearing away heat and cooling blood, the function of dissipating blood stasis.Be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, abdominal mass stomachache, traumatic injury, diseases such as carbuncle skin infection.
The Radix Astragali: slightly warm in nature, sweet in the mouth.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance is arranged, hidroschesis, poison holding, granulation promoting, the effect of diuresis detumescent.Cure mainly deficient qi and blood, refreshing tired lack of appetite, chronic diarrhea proctoptosis, exterior deficiency be from apogee sweating, and blood deficiency wind-engaging, numbness of the skin, skin sore are not burst or are burst and do not hold back for a long time and card such as hydroderma.Process and use QI invigorating, give birth to and use consolidating superficial resistance, the holder skin ulcer.Caulis Lonicerae: sweet, cold.Attach to the lung and stomach meridians.Has heat-clearing and toxic substances removing, the function of dispelling wind collateral dredging.
Clinical application effect: the flat rheumatism hospital of English and the flat rheumatism hospital of Changchun English drop into clinic trial to the granule product among the present invention at Chongwen, Beijing, and typical dry syndrome patients estimate method to 72 examples: adopt at random, the principle of non-blind, contrast.36 examples are organized in treatment, 3 times/d of oral replenishing body fluid and clearing away heat pathogen granule, and each 1 bag, 28d is a course of treatment, totally 3 courses of treatment; Matched group 36 examples give the oxychloroquine treatment.The result: the replenishing body fluid and clearing away heat pathogen granule is at the clinical symptoms of improving the patient and sign (P < 0.01) evident in efficacy; For increasing patient's saliva amount significant curative effect (P < 0.01) is arranged; Hemocytes increasing is had obvious curative effects (P < 0.01), and comprehensive therapeutic effect is superior to matched group.Aspect safety, two groups all have good safety.
Embodiment 1
200 parts of 1200 portions of Flos Loniceraes of Gypsum Fibrosum
70 parts of 70 parts of Pseudobulbus Cremastrae Seu Pleiones of Cortex Moutan
2000 parts of 200 parts of Herba Hedyotidis Diffusaes of Radix Gentianae Macrophyllae
70 parts of 200 parts of Radix Puerariaes of Radix Scrophulariae
200 parts of 200 parts of Semen Coiciss of Rhizoma Arisaematis
70 parts of 200 parts of Radix Paeoniae Rubra of Radix Rehmanniae
200 parts of 200 parts of Caulis Loniceraes of the Radix Astragali.
Preparation technology: get Gypsum Fibrosum, Rhizoma Arisaematis adds 2-7 times of decocting and boils 1-5 time, each 1-4 hour, being concentrated into density was 1.0-2.0 (50-90 ℃); Remain 12 flavor medical materials and add 2-7 times of water gaging, decoct 1-5 time, each 1-4 hour, collecting decoction; Filter, be concentrated into density 1.0-2.0 (50-90 ℃), add ethanol and stir that to be adjusted to concentration be 50-90%; Leave standstill, get supernatant and filter, decompression recycling ethanol is to there not being the alcohol flavor; Filtered solution and Gypsum Fibrosum, the Rhizoma Arisaematis decocting liquid of 12 flavor medical materials are merged, and drying is ground into fine powder; Fine powder and dextrin are pressed the 1:2-5 mix homogeneously, are that binding agent is granulated with 50-90% ethanol, and 50-90 ℃ of drying processed 500-2500g, promptly gets.
The described a kind of Chinese medicine granules of treating dry syndrome that adopts this proportioning to process has 8 people to take in clinical, every day three times, each bag, warm water delivery service.Take reached that eye is done in 28 days, xerostomia, xerosis cutis symptom alleviate 2 examples, takes that 56 days eyes are done, xerostomia, xerosis cutis symptom alleviate 2 examples, has 4 examples still treating through changing proportioning after 56 days.
Model case: Mrs Ji, 41 years old
The patient whole body joint repeated relapsing pain occurs because of no inducement before 4 years, and does with being interrupted heating, xerostomia, eye, once at local hospital admission; Chemical examination RF++, ESR20mm/h, SSA (+); SSB (+); Immunosuppressant and hormone therapy are taken in diagnosis " rheumatoid arthritis, sjogren syndrome ", and the state of an illness increases the weight of.My institute of going to a doctor in 2009, diagnosis is the same, gives oral embodiment of the invention Chinese medicine granules and the Comprehensive Treatment 28 days of being admitted to hospital, and is heavy when light during the symptom of joint, but a mouthful xerophthalmia scheorma symptom alleviates.
Embodiment 2
300 parts of 1500 portions of Flos Loniceraes of Gypsum Fibrosum
100 parts of 100 parts of Pseudobulbus Cremastrae Seu Pleiones of Cortex Moutan
300 parts of 300 parts of Herba Hedyotidis Diffusaes of Radix Gentianae Macrophyllae
100 parts of 300 parts of Radix Puerariaes of Radix Scrophulariae
300 parts of 300 parts of Semen Coiciss of Rhizoma Arisaematis
100 parts of 300 parts of Radix Paeoniae Rubra of Radix Rehmanniae
300 parts of 300 parts of Caulis Loniceraes of the Radix Astragali.
Preparation technology: get Gypsum Fibrosum, Rhizoma Arisaematis adds 2-7 times of decocting and boils 1-5 time, each 1-4 hour, being concentrated into density was 1.0-2.0 (50-90 ℃); Remain 12 flavor medical materials and add 2-7 times of water gaging, decoct 1-5 time, each 1-4 hour, collecting decoction; Filter, be concentrated into density 1.0-2.0 (50-90 ℃), add ethanol and stir that to be adjusted to concentration be 50-90%; Leave standstill, get supernatant and filter, decompression recycling ethanol is to there not being the alcohol flavor; Filtered solution and Gypsum Fibrosum, the Rhizoma Arisaematis decocting liquid of 12 flavor medical materials are merged, and drying is ground into fine powder; Fine powder and dextrin are pressed the 1:2-5 mix homogeneously, are that binding agent is granulated with 50-90% ethanol, and 50-90 ℃ of drying processed 500-2500g, promptly gets.
The described a kind of Chinese medicine granules of treating dry syndrome that adopts this proportioning to process has 8 people to take in clinical, every day three times, each bag, warm water delivery service.Take reached that eye is done in 28 days, xerostomia, xerosis cutis symptom alleviate 4 examples, takes that 56 days eyes are done, xerostomia, xerosis cutis symptom alleviate 4 examples.
Model case: Ms Zhang 50 years old
This trouble did not have obvious inducement because of 2003 and finger-joint pain occurs, and gradually stiff morning to whole body arthralgia companion, back symptom alleviates voluntarily, does not take notice of.Thereafter the state of an illness again and again began to be interrupted before 5 years and takes strong bone capsule (being suspected to have the hormone composition), and the state of an illness is alleviated.Xerostomia appears then, eye is done, and the time swallow dryness food difficulty.Came me institute to go to a doctor chemical examination: rheumatoid factor on JIUYUE 2nd, 2009 ++ ++, erythrocyte sedimentation rate 115mm/h, anti-" O " 200
U, RO-52 (+) resists-SSA (+), routine blood test HGB92g/L.X-ray film shows both hands, two knee joint, both shoulders, two ankle joint inflammation; Lumbar vertebra hyperosteogeny; Be diagnosed as " rheumatoid arthritis, sjogren syndrome ", give oral embodiment of the invention Chinese medicine granules and Comprehensive Treatments such as treatment are treated, exempted to the promoting the circulation of blood liquid light quantum intraoperative autologous blood transfusion of being admitted to hospital, calcium, the joint symptom obviously alleviates; And a mouthful xerophthalmia scheorma symptom disappears, and joint motion freely.
Embodiment 3
450 parts of 3000 portions of Flos Loniceraes of Gypsum Fibrosum
180 parts of 180 parts of Pseudobulbus Cremastrae Seu Pleiones of Cortex Moutan
450 parts of 450 parts of Herba Hedyotidis Diffusaes of Radix Gentianae Macrophyllae
180 parts of 450 parts of Radix Puerariaes of Radix Scrophulariae
450 parts of 450 parts of Semen Coiciss of Rhizoma Arisaematis
180 parts of 450 parts of Radix Paeoniae Rubra of Radix Rehmanniae
450 parts of 450 parts of Caulis Loniceraes of the Radix Astragali
Preparation technology: get Gypsum Fibrosum, Rhizoma Arisaematis adds 2-7 times of decocting and boils 1-5 time, each 1-4 hour, being concentrated into density was 1.0-2.0 (50-90 ℃); Remain 12 flavor medical materials and add 2-7 times of water gaging, decoct 1-5 time, each 1-4 hour, collecting decoction; Filter, be concentrated into density 1.0-2.0 (50-90 ℃), add ethanol and stir that to be adjusted to concentration be 50-90%; Leave standstill, get supernatant and filter, decompression recycling ethanol is to there not being the alcohol flavor; Filtered solution and Gypsum Fibrosum, the Rhizoma Arisaematis decocting liquid of 12 flavor medical materials are merged, and drying is ground into fine powder; Fine powder and dextrin are pressed the 1:2-5 mix homogeneously, are that binding agent is granulated with 50-90% ethanol, and 50-90 ℃ of drying processed 500-2500g, promptly gets.
The described a kind of Chinese medicine granules of treating dry syndrome that adopts this proportioning to process has 8 people to take in clinical, every day three times, each bag, warm water delivery service.Take reached that eye is done in 28 days, xerostomia, xerosis cutis symptom alleviate 5 examples, takes that 56 days eyes are done, xerostomia, xerosis cutis symptom alleviate 3 examples.
Model case: Mrs Jia 50 years old
This trouble double knee joint pain occurs because of catching a cold because of in February, 2008 after the operation of both hands carpal tunnel syndrome, swelling, and the whole body arthralgia that continues is outstanding with extremities joint symmetry pain, swelling, morning is stiff, and xerostomia, eye are done.Be in hospital 3 month to college of traditional Chinese medicine's rheumatism hospital diagnosis " rheumatoid arthritis, sjogren syndrome " in January, 2009, and oral decoction etc. are not seen and are clearly better.On March 17th, 2009, the prescription on individual diagnosis college of traditional Chinese medicine chemically examined: RF-, ESR57mm/h, ASO200
UHematuria is conventional, anti-SSA+, and anti-SSB+, anti-dsDNA-, came me institute to go to a doctor on 26th, diagnosis is the same, gives oral embodiment of the invention Chinese medicine granules parallel Comprehensive Treatment, and arthralgia alleviates, and a mouthful xerophthalmia scheorma symptom is alleviated.
Should be understood that application of the present invention is not limited to above-mentioned giving an example, concerning those of ordinary skills, can improve or conversion that all these improvement and conversion all should belong to the protection domain of accompanying claims of the present invention according to above-mentioned explanation.
Claims (3)
1. a Chinese medicine composition of treating dry syndrome is characterized in that, counts by weight, and is mainly composed of the following components:
Gypsum Fibrosum 1200-3000 part Flos Lonicerae 200-450 part
Cortex Moutan 70-180 part Pseudobulbus Cremastrae Seu Pleiones 70-180 part
Radix Gentianae Macrophyllae 200-450 part Herba Hedyotidis Diffusae 2000-450 part
Radix Scrophulariae 200-450 part Radix Puerariae 70-180 part
Rhizoma Arisaematis 200-450 part Semen Coicis 200-450 part
Radix Rehmanniae 200-450 part Radix Paeoniae Rubra 70-180 part
Radix Astragali 200-450 part Caulis Lonicerae 200-450 part.
2. the Chinese medicine composition of treatment dry syndrome according to claim 1 is characterized in that, the Chinese medicine composition of said treatment dry syndrome is a granule.
3. the method for preparing of the Chinese medicine composition of a treatment dry syndrome as claimed in claim 2 is characterized in that, may further comprise the steps:
Get Gypsum Fibrosum, Rhizoma Arisaematis adds 2-7 times of decocting and boils 1-5 time, each 1-4 hour, being concentrated into density was 1.0-2.0;
Get residue 12 flavor medical materials and add 2-7 times of water gaging, decocts 1-5 time, each 1-4 hour, collecting decoction, filtration is concentrated into density 1.0-2.0, adds ethanol and stirs that to be adjusted to concentration be 50-90%, leaves standstill, and gets the supernatant filtration, reclaim under reduced pressure;
Filtered solution and Gypsum Fibrosum, the Rhizoma Arisaematis decocting liquid of 12 flavor medical materials are merged, and drying is ground into fine powder;
Fine powder and dextrin are pressed the 1:2-5 mix homogeneously, are that binding agent is granulated 50-90 ℃ of drying with 50-90% ethanol.
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Cited By (5)
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| CN102935177A (en) * | 2012-12-08 | 2013-02-20 | 南京正宽医药科技有限公司 | Traditional Chinese medicine composition for treating sjogren syndrome as well as preparation method and application thereof |
| CN103263620A (en) * | 2013-06-09 | 2013-08-28 | 张玉华 | Traditional Chinese medicine preparation for treating sjoegren syndrome and preparation method thereof |
| CN103585352A (en) * | 2013-11-25 | 2014-02-19 | 重庆市中药研究院 | Traditional Chinese medicinal composition for yin nourishing and pathogenic fire reducing, and its application |
| CN104306721A (en) * | 2014-11-07 | 2015-01-28 | 朱海燕 | Traditional Chinese medicine composition for sjogren syndrome as well as preparation method and application |
| CN107669889A (en) * | 2017-09-28 | 2018-02-09 | 北京中医药大学 | Treat pharmaceutical composition of Sjogren syndrome and its production and use |
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| CN101121013A (en) * | 2006-08-07 | 2008-02-13 | 郭占友 | Medicine for treating intractable oral cavity ulcer, Baiser's disease and sjogren syndrome and manufacturing method |
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| CN101121013A (en) * | 2006-08-07 | 2008-02-13 | 郭占友 | Medicine for treating intractable oral cavity ulcer, Baiser's disease and sjogren syndrome and manufacturing method |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102935177A (en) * | 2012-12-08 | 2013-02-20 | 南京正宽医药科技有限公司 | Traditional Chinese medicine composition for treating sjogren syndrome as well as preparation method and application thereof |
| CN102935177B (en) * | 2012-12-08 | 2014-08-13 | 新乡医学院第一附属医院 | Traditional Chinese medicine composition for treating sjogren syndrome as well as preparation method and application thereof |
| CN103263620A (en) * | 2013-06-09 | 2013-08-28 | 张玉华 | Traditional Chinese medicine preparation for treating sjoegren syndrome and preparation method thereof |
| CN103263620B (en) * | 2013-06-09 | 2014-12-31 | 张玉华 | Traditional Chinese medicine preparation for treating sjoegren syndrome and preparation method thereof |
| CN103585352A (en) * | 2013-11-25 | 2014-02-19 | 重庆市中药研究院 | Traditional Chinese medicinal composition for yin nourishing and pathogenic fire reducing, and its application |
| CN103585352B (en) * | 2013-11-25 | 2015-07-15 | 重庆市中药研究院 | Traditional Chinese medicinal composition for yin nourishing and pathogenic fire reducing, and its application |
| CN104306721A (en) * | 2014-11-07 | 2015-01-28 | 朱海燕 | Traditional Chinese medicine composition for sjogren syndrome as well as preparation method and application |
| CN107669889A (en) * | 2017-09-28 | 2018-02-09 | 北京中医药大学 | Treat pharmaceutical composition of Sjogren syndrome and its production and use |
| CN107669889B (en) * | 2017-09-28 | 2020-08-04 | 北京中医药大学 | Pharmaceutical composition for treating sicca syndrome and preparation method and application thereof |
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