CN102552568B - Chinese medicine preparation for curing leukemia and aplastic anemia - Google Patents

Abstract

The invention relates to a Chinese medicine preparation for curing leukemia and aplastic anemia, which is composed of twenty Chinese medicines including cornu bubali, fresh live deer bone marrow, radix angelicae pubescentis, panax notoginseng, rhizoma curculiginis, pokeberry root, codonopsis pilosula, Chinese angelica, hairyvein agrimony, colla corii asini, hedyotis diffusa, caulis spatholobi, astragalus mongholicus, human placenta, tortoise-plastron glue, dahurian patrinia herbs, the seed of Chinese dodder, Chinese fevervine herbs, cordyceps sinensis and fresh antelope livers. The Chinese medicine preparation is used for curing patients suffering from the leukemia within in 150 days and accepting the chemical therapy smaller than two times (a chemical therapy medicine does not selectively kill cancer cells only, a hemopoietic system can be damaged easily and severely by the chemical therapy medicine, and the more the chemical therapy is, the more difficult the patients are cured). 98% of patients suffering from the aplastic anemia within six months can relieve symptoms, and about 90% of the aplastic anemia patients can be cured after taking the Chinese medicine preparation for fifty days. The Chinese medicine preparation is preferred to cure the leukemia and the aplastic anemia at present because used Chinese medicine medicinal pieces (such as the cornu bubali, the fresh live deer bone marrow, the colla corii asini, the human placenta, the tortoise-plastron glue, the cordyceps sinensis and the fresh antelope livers) are medicinal and edible green foods, free of toxic and side effects and covenient to take.

Description

A kind ofly treat leukemic Chinese medicine preparation

Technical field:

The present invention is a kind of leukemic Chinese medicine preparation for the treatment of, and belongs to the technical field of Chinese medicine production application and preparation method.

Background technology:

Leukemia is the hematologic disease often running into clinically, and main manifestations has leukaemia's hypertrophy and invades profit.Non-specific pathological changes is hemorrhage and histotrophic nutrition is bad and downright bad, secondary infection etc.Leukaemia's hypertrophy and invade profit and mainly occur in bone marrow and other hemopoietic tissue, also can appear in other tissue of whole body, causes normal erythroid cells, Megakaryocyte significantly to reduce.Can be because of some leukaemia's obvious proliferation or extremely active in bone marrow, and present bois de rose or yellow green.Lymphoid tissue also can be invaded profit by leukaemia, stage lymphadenectasis.There is leukemia the dead of 50%--80% to have obvious central nervous system leukemia to change.Common person is cytostasis in blood vessel, blood vessel peripheral white blood cells hypertrophy.Leukemia the most often occurs for other, and to invade the internal organs of profit be kidney, lung, heart and thymus, testis etc.By above elaboration, can find out, leukemia is invaded profit and is organized internal organs relatively more concentrated and serious, and disorganize ability is larger.Leukemia is in lysis, and mostly hemorrhage with in various degree, can occur in any position, but is more common in hemopoietic tissue, mucocutaneous, pericardium, spleen, stomach and nervus centralis etc.It is hemorrhage often occurs on the basis that leukaemia invades profit, because leukaemia invades profit, hemorrhage, infarction and general metabolism obstacle, local or all tissues can nutritious bad and atrophy, even downright bad etc.Due to chemotherapeutics and antibiotic application in a large number, dead rear neuropathology changes has new performance, leukaemia's disintegrate to invade profit disappearance, has occurred Fibrin exudation in recent years, and histiocyte is engulfed, then fibrosis.Can there is atrophy or fibrosis in bone marrow, the infection of some mycete, protozoon increases, and drug-induced pathological changes increases.Present known leukemia is a kind of clone's property malignant diseases, and malignant change can occur in hematopoietic stem cell broad range, and how many scopes of involving can differ.The generation of malignant clone may be relevant with many factors, and wherein the former tumor gene activation of retroviral infection is main.And lonizing radiation, chemical toxicant, medicine (particularly alkylating agent) and inherited genetic factors cause generation and the development that chromosomal abnormality and Immune Dysfunction etc. have impelled malignant clone.Some disease of hematopoietic system, as bone marrow appreciation disease, myelodysplastic syndrome, paroxysmal nocturnal hemoglobinuria and lymphoma etc. finally also can be converted into leukemia.

Leukemia doctor trained in Western medicine often adopts the methods such as " chemotherapy ", " bone marrow transplantation " and " stem cell transplantation " in treatment, along with the increase of chemotherapy, (chemotherapy is not selectively for cancerous cell, to kill and wound, more severe to hemopoietic system damage), but worse and worse (chemotherapy has been destroyed whole body's immunity and hemopoietic system to curative effect, resist the ability degradation of disease), final effect is not good." bone marrow transplantation " and " stem cell transplantation ", implement to join type very difficult, and expense is huge, and cure rate is not high yet.Therefore numerous leukemic patients that are murdered urgently a kind of taking convenience, the Chinese medicine preparation that evident in efficacy, cure rate is high come out.

Summary of the invention:

Object of the present invention is just to provide a kind of taking convenience, sphere of action is wide, effect is remarkable, have no side effect a kind ofly treat leukemic Chinese medicine preparation.

The present invention is comprised of Cornu Bubali, fresh and alive Os Cervi marrow, Radix Angelicae Pubescentis, Radix Notoginseng, Rhizoma Curculiginis, Radix Phytolaccae, Radix Codonopsis, Radix Angelicae Sinensis, Herba Agrimoniae, Colla Corii Asini, Herba Hedyotidis Diffusae, Caulis Spatholobi, the Radix Astragali, Placenta Hominis, Colla Plastri Testudinis, Herba Patriniae, Semen Cuscutae, Herba Paederiae, Cordyceps, the fresh and alive Saigae Tataricae liver 20 taste prepared slices of Chinese crude drugs.

Specific implementation method:

Standard formula: Cornu Bubali 10g, fresh and alive Os Cervi marrow 20g, Radix Angelicae Pubescentis 6g, Radix Notoginseng 6g, Rhizoma Curculiginis 6g, Radix Phytolaccae 6g, Radix Codonopsis 9g, Radix Angelicae Sinensis 9g, Herba Agrimoniae 6g, Colla Corii Asini 20g, Herba Hedyotidis Diffusae 8g, Caulis Spatholobi 20g, Radix Astragali 14g, Placenta Hominis 10g, Colla Plastri Testudinis 12g, Herba Patriniae 8g, Semen Cuscutae 6g, Herba Paederiae 6g, Cordyceps 6g, fresh and alive Saigae Tataricae liver 12g, totally 200 grams.

Preparation technology is as follows:

1, the raw material prepared slices of Chinese crude drugs are weighed standby by standard formula.

2, the raw material of getting ready is put under burning sun, be exposed to the sun or baking box in dehydrate, fresh and alive Os Cervi marrow and fresh and alive Saigae Tataricae liver are put tile and dry.

3, the crude drug of drying and dehydrating is put into high speed medicinal material pulverizer, pulverizing is the above medicated powder of 120 order.

4, by the medicated powder ultraviolet disinfection crushing, by 10 grams/packing, standby.

Use prescription solution: Cornu Bubali, bitter, cold, GUIXIN, Liver Channel, impel platelet growth, Os Cervi marrow, marrow-supplementing and blood-engendering, impels hematopoietic function recovery, Radix Angelicae Pubescentis, pungent, bitter, tepor, returns kidney, urinary bladder channel, anti-inflammatory and antalgic, antitumor, has hormone-like effect, and for thrombocytopenic purpura, Radix Notoginseng, sweet, micro-hardship, temperature, returns liver, stomach warp, has anastalsis, can anti-treating leukemia because of thrombocytopenia histoorgan hemorrhage, Rhizoma Curculiginis, pungent, hot, poisonous, return kidney,liver,spleen warp, kidney-replenishing, bone and muscle strengthening, antiinflammatory, can strengthen the compatibilities such as immunologic function, and Radix Angelicae Sinensis, is used for the treatment of leukemia anemia, Radix Phytolaccae, bitter, cold, poisonous, return lung, spleen, kidney, large intestine channel, can improve immunity, antitumor, for thrombocytopenic treatment, Radix Codonopsis, sweet, flat, return spleen, lung meridian, invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, enhancing body emergency capability and body's immunity, for the hematopoietic disorder due to functional bleeding or chemotherapy, Radix Angelicae Sinensis, sweet, pungent, warm, return liver, the heart, spleen channel, enrich blood and invigorate blood circulation, promote hematopoietic cell proliferation differentiation, antiinflammatory, antitumor, Herba Agrimoniae, pungent, hot, poisonous, return kidney,liver,spleen warp, kidney-replenishing, bone and muscle strengthening, antiinflammatory, strengthens immunologic function, is used for the treatment of anemia, Colla Corii Asini, enriches blood, stops blooding, YIN nourishing, moisturize, main blood deficiency disease, asthenia spitting of blood, haematemesis, hematuria, have blood in stool, dysentery, hemopoietic system is had to powerful blood tonification effect, Herba Hedyotidis Diffusae, heat-clearing and toxic substances removing, dampness removing dissipating blood stasis, can be used for the mass formed by blood stasis of various bleeding due to blood-heaies, also can be used for treating tumor, Caulis Spatholobi, bitter, sweet, warm, return liver, kidney channel, enrich blood, invigorate blood circulation and dredging collateral effect, can impel hemocyte to increase, hemoglobin raises, and also has antitumor action, the Radix Astragali, invigorating QI to consolidate the body surface resistance, can increase immunity of organisms, for sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, burst and do not hold back for a long time, blood deficiency and yellow complexion, enhancing body anoxia enduring and stress ability, antibacterial and antiviral effect and hormone-like effect, sweet in the mouth, feeble QI temperature, gas is thin and taste is dense, can rise and can fall, the yang aspect of yang also, nontoxic, start with lunar, foot is lunar, the warp of the few the moon of hands, its function is a lot of, and its only effect person, especially enriching blood, the Radix Astragali is the panacea of QI invigorating, there is again the effect of enriching blood, lid gas is invisible, blood is tangible, tangible can not fast-growing, gas that must be invisible is with life, the Radix Astragali and Radix Angelicae Sinensis are with using, can help with hemopoietic, Placenta Hominis, i.e. the mankind's Placenta Hominis, nature and flavor are sweet, salty, warm, enter lung, the heart, kidney channel, useful smart the kidney invigorating, the effect of benefiting QI and nourishing blood, modern medicine study, Placenta Hominis is containing protein, sugar, calcium, vitamin, immune factor etc., edible can have building body, increases the ability of resisting disease, Colla Plastri Testudinis, is Testudinis sternite, and through decocting, the concentrated solid gum of making, property is partially gentle, and sweet in the mouth and salty has the effect of YANG hyperactivity suppressing YIN nourishing, replenishing kidney and strengthening bone, and has the effect of tonifying blood and arresting bleeding concurrently, Herba Patriniae, pungent, bitter, be slightly cold, return kidney, large intestine, Liver Channel, heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood stasis dispelling relieves the pain, and has antitumor action, Herba Paederiae, heat clearing away, removing toxic substances, the function of drying, enriching blood, is " soil ginseng " therefore among the people, have good spleen invigorating effect, Cordyceps, a kind of traditional famous and precious tonic Chinese medicine material, has the multiple efficacies such as the function of immune system of adjusting, antitumor, resisting fatigue, and has the effect of lung-yin nourishing, kidney-replenishing, the raw marrow of bone strengthening, nourishing the lung and kidney, hemostasis, fresh and alive Saigae Tataricae liver, enters liver, the heart, lung meridian, main removing fire from the liver, and the lung that clears away heart-fire, tonifying liver, promote hemopoietic.

Embodiment 1. Wang Jianjuns, man, 63 years old, people from Huaiyin District, Jinan, medical officer, suffer from acute leukemia sick 50 days, in be in hospital chemotherapy 3 times of General Hospital of Jinan Military Command, effect is bad, platelet, erythrocyte is low, bone is worn juvenile cell 85%, malaise, spitting of blood, inappetence, face jaundice, pulse condition is faint, be unable to leave the bed, subcutaneous purpura, by platelet transfusion, maintain, in family, younger brother advises with treatment by Chinese herbs, find us, the present patent application people's General Hospital of Jinan Military Command of paying a home visit, see its crisis, also without absolutely holding, patient wears masks, microphonia, household agrees to take treatment by Chinese herbs of the present invention, take after 10 days, stopped bleeding, subcutaneous purpura disappears, appetite muscle power all increases, hemogram is chemically examined blood test platelet again, hemoglobin rises, leukopenia, bone marrow aspiration juvenile cell ratio declines, antisecosis is very large, why body is 5 jin, family always, continue to take Chinese medicine of the present invention, after treatment 20 days, bone puncture juvenile cell is normal, muscle power is recovered completely, have rosy cheeks, appetite increases, body weight goes back up to the front weight of disease.After 5 years, follow up a case by regular visits to health, reach clinical cure object.

Embodiment 2. Li Jun, man, 14 years old, Yuegongqiao people, low grade fever, arthralgia more than 10 days, to Zhangqiu, seek medical advice in the People's Hospital, hemogram check platelet, hemoglobin are low, leukemia is high, and bone marrow aspiration juvenile cell 96% is accepted chemotherapy at random in hospital, chemotherapy is after the course for the treatment of, react huge, physical degradation, hair starts to take off.The head of a family seeks Chinese traditional treatment, while finding us, and pale complexion, pulse condition is faint, 118 beats/min of hearts rate, are used preparation for treating of the present invention 10 days, do hemogram and check platelet, hemoglobin, leukemia to approach normal value, and bone marrow aspiration is not done, face is ruddy gradually, takes after 30 days transference cure.Hemogram check platelet, hemoglobin, leukemia be complete normal range all, and bone marrow juvenile cell 3%, continues to strengthen treatment 20 days, and all are normal to detect chemical examination, recover what vigor of teenager, reach clinical cure object.

Claims (2)

1. treat leukemic Chinese medicine preparation for one kind, it is characterized in that all take that the prepared slices of Chinese crude drugs are as raw material, wherein Cornu Bubali 10g, fresh and alive Os Cervi marrow 20g, Radix Angelicae Pubescentis 6g, Radix Notoginseng 6g, Rhizoma Curculiginis 6g, Radix Phytolaccae 6g, Radix Codonopsis 9g, Radix Angelicae Sinensis 9g, Herba Agrimoniae 6g, Colla Corii Asini 20g, Herba Hedyotidis Diffusae 8g, Caulis Spatholobi 20g, Radix Astragali 14g, Placenta Hominis 10g, Colla Plastri Testudinis 12g, Herba Patriniae 8g, Semen Cuscutae 6g, Herba Paederiae 6g, Cordyceps 6g, fresh and alive Saigae Tataricae liver 12g, be total to 200g.

2. a preparation method for the treatment of leukemic Chinese medicine preparation is as follows:

(1), the raw material prepared slices of Chinese crude drugs are weighed standby.Cornu Bubali 10g, fresh and alive Os Cervi marrow 20g, Radix Angelicae Pubescentis 6g, Radix Notoginseng 6g, Rhizoma Curculiginis 6g, Radix Phytolaccae 6g, Radix Codonopsis 9g, Radix Angelicae Sinensis 9g, Herba Agrimoniae 6g, Colla Corii Asini 20g, Herba Hedyotidis Diffusae 8g, Caulis Spatholobi 20g, Radix Astragali 14g, Placenta Hominis 10g, Colla Plastri Testudinis 12g, Herba Patriniae 8g, Semen Cuscutae 6g, Herba Paederiae 6g, Cordyceps 6g, fresh and alive Saigae Tataricae liver 12g, altogether 200g;

(2), the raw material weighing up is put and under burning sun, is exposed to the sun or dries, dehydrate, fresh and alive Os Cervi marrow and fresh and alive Saigae Tataricae liver baking box are dried or are put on tile and dry;

(3), the crude drug after drying and dehydrating is put into high speed medicinal material pulverizer, pulverizing is the above medicated powder of 120 order;

(4), by the raw material Chinese medicine powder ultraviolet disinfection of drying and dehydrating, by 10 grams/packing, standby.