CN102550857B - Functional feed for preventing and treating mastitis in dairy cows and preparation method thereof - Google Patents

Functional feed for preventing and treating mastitis in dairy cows and preparation method thereof Download PDF

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CN102550857B
CN102550857B CN2011104277946A CN201110427794A CN102550857B CN 102550857 B CN102550857 B CN 102550857B CN 2011104277946 A CN2011104277946 A CN 2011104277946A CN 201110427794 A CN201110427794 A CN 201110427794A CN 102550857 B CN102550857 B CN 102550857B
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弓瑞珠
叶亚东
关会营
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BEIJING JIUZHOU DADI BIOLOGICAL TECHNOLOGY GROUP Co.,Ltd.
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BEIJING KEXING DADI FEED CO LTD
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Abstract

The invention discloses a functional feed for preventing and treating mastitis in dairy cows and a preparation method of the feed. The functional feed contains the following raw materials in parts by weight: 0.2 to 0.5 part of probiotics, 40 to 60 parts of corn, 8 to 15 parts of wheat bran, 5 to 15 parts of dehulled soybean meal, 5 to 10 parts of corn distillers'grains, 5 to 15 parts of dephenolized cotton meal, 4 to 10 parts of cotton meal, 2 to 5 parts of shorts, 3 to 4 parts of calcium hydrogen phosphate, 1.5 to 2 parts of shorts and stone powders, 2 to 3 parts of rumen fat powders, 1.0 to 1.5 parts of baking soda, 0.5 to 1.0 parts of magnesium oxide, 0.3 to 0.8 part of sodium chloride, 1 to 2 parts of molasses, 1 to 1.5 parts of premix for lactating cows and 0.5 to 1 part of sodium sulfate. The results of the study in dairy cows show that the functional feed can reduce the number of somatic cells of dairy cows and can effectively prevent the incidence and development of mastitis in dairy cows.

Description

A kind of functional feed of preventing and treating mastitis for milk cows and preparation method thereof
Technical field
The present invention relates to a kind of functional feed of preventing and treating mastitis for milk cows and preparation method thereof.
Background technology
Mammitis is the common disease of milk cow, is a kind of disease to milk cow production harmfulness maximum.According to statistics, clinic mastitis accounts for 21%~23% of the total morbidity of milk cow, and mammitis causes the milk amount to descend, and sick cow's milk is discarded; Suppurate in severe patient breast district, gangrenous, atrophy, causes forever to lose milking capacity, causes serious economy loss.
Mammitis morbidity shows as: breast has inflammation such as red, swollen, hot, pain to show; Lactation reduces or stops; Milk changes; Appetite descends.Asymptomatic recessive mastitis is higher than clinic mastitis, and its incidence of disease accounts for 50% of whole cows, because trouble cow's milk room and milk do not have obvious macroscopic variation, thus be difficult to find, so that often do not paid attention to by the people.
The pathogenic factor of mammitis mainly is because the intrusion of pathogen, and the various inducements that cause infection, and as wound, the technology of milking are not good, environmental sanitation is bad, feeding and management is inappropriate, hormonal imbalance, breast defective and other diseases bring out etc.The pathogenic microorganism more complicated of mammitis comprises that bacterium, fungi, Mycoplasma, saccharomycete, virus etc. can reach kind more than 80.
Also do not reduce the special feed of the mastitis for milk cows incidence of disease in the market.Traditional therapy adopts antibiotherapy more, local penicillin, streptomysin, terramycin, the kanamycins etc. of using of breast.For a long time, not only easily develop immunity to drugs, therapeutic process is long, and dosage is big, usually produce antibiotic milk, can not sell as commodity milk, waste hugely, have a strong impact on economic benefit, and, after the milk cow morbidity, have a delicate constitution, feed intake obviously descends, and irremediable having a strong impact on caused in peak period and the full phase output of milk.
Summary of the invention
The purpose of this invention is to provide a kind of functional feed of preventing and treating mastitis for milk cows and preparation method thereof.
The functional feed of control mastitis for milk cows provided by the present invention is made up of the raw material of following mass parts: probio 0.2-0.5 part, corn 40-60 part, wheat bran 8-15 part, decortication dregs of beans 5-15 part, maize alcohol lees 5-10 part, dephenolize cotton dregs 5-15 part, cotton dregs 4-10 part, inferior powder 2-5 part, calcium monohydrogen phosphate 3-4 part, stone flour 1.5-2 part, rumen-undegraded fat powder 2-3 part, sodium bicarbonate 1.0-1.5 part, magnesia 0.5-1.0 part, sodium chloride 0.3-0.8 part, molasses 1-2 part, cow producing milk phase premix 1-1.5 part and sodium sulphate 0.5-1 part.
Contain vitamin A 1150000.0IU, calciferol 50000.0IU, vitamin E 12450.0mg, copper 1370.0mg, iron 8884.0mg, zinc 8076.0mg, manganese 4084.0mg, iodine 4.0mg, selenium 48.0mg, cobalt 22.0mg in the above-mentioned per kilogram cow producing milk phase premix, surplus is carrier.
Above-mentioned probio mainly is made up of the mixture of bacillus subtilis B7348, lactic acid bacteria LP-11 and antibacterial metabolite thereof.Wherein the quality of bacillus subtilis B7348 accounts for 80%, and viable bacteria content is 2 * 10 8The CFU/ gram, the quality of lactic acid bacteria LP-11 and antibacterial metabolite thereof accounts for 20%, and viable bacteria content is 2.2 * 10 8The CFU/ gram.
The above-mentioned molasses molasses that preferably ferment.The purity of above-mentioned raw materials is the conventional purity of feed grade raw material.
The preparation method of the functional feed of control mastitis for milk cows provided by the present invention comprises the steps:
Each component of forming described functional feed is carried out weighing according to proportioning, pulverize then, mix, mixture is carried out modified, granulation, obtain feed granules.
Wherein, described modified temperature is 40 ℃-70 ℃, and the modified time is 20-60 second.
Used probio is processed through bag, can tolerate 85 ℃ of high temperature granulating.
Mammitis is the important diseases that the harm dairy develops in a healthy way, and therefore, prevention and treatment mammitis just become the important process of current cattle farm.(Somatic cell count is a whether important indicator of inflammation (comprising recessive mastitis) of reflection breast SCC) to Ruzhong body cell counting, and the breast infection degree is more high, and the Ruzhong somatic number is more many.Usually milk cow body cell numerical value height usually is because breast has been subjected to bacterial infection institute extremely, therefore reduces the best method of body cell numerical value and protects from infection exactly.And the antibacterial peptide that microbial metabolism produces, bacteriocin etc. optionally kill external pathogenic bacteria and wide spectrum suppresses Gram-negative and positive pathogenic bacterium, avoids milk cow to produce a large amount of leucocytes and is discharged into mammary gland, reduces somatic purpose thereby reach.The subtilin that contained bacillus subtilis B7348 metabolism produces in the probio of the present invention, Gram-negative bacteria and gram-positive bacteria to high pathological form have potent inhibition killing action, can improve milk cow to the resistivity of external pathogenic bacteria, effectively reduce body cell, reduce the mammitis incidence of disease, improve milk quality; The lactein that contained lactic acid bacteria LP-11 metabolism produces is small-molecule peptide, optionally kills pathogenic entero becteria, and lactic acid bacteria and alimentary canal stick formation mycoderm barrier, stop the cause of disease invasion and attack.
The smart feed supplement of control mastitis for milk cows functional particles provided by the present invention contains protein, carbohydrate, vitamin, mineral matter and a large amount of probios etc.; Compare with milk cow material in the market, the present invention has following beneficial effect:
1, the present invention is that specialization is at the dedicated functionality feed product of mastitis for milk cows problem exploitation; Take into full account milk cow digestive physiological characteristics and nutritional need, select the quality raw materials of the high nutrient concentration of digestibility height, good palatability, by accurate Calculation and repeatedly animal experiment determine its suitable proportion and composition form.
2, the present invention has taken into full account the actual conditions of mastitis for milk cows generation, development, adds the specific aim probio especially, and is easy to use, effectively prevents generation, the development of mastitis for milk cows.
3, the smart particulate material of mending provided by the invention has specific aim preferably, can effectively promote cow feeding.
4, in actual production, have preferably palatability, can effectively promote cow feeding, replenish dairy cow nutrition fast, reduce milk cow body weight in postpartum and reduce, effectively prevent generation, the development of mastitis for milk cows.
The specific embodiment
For a better understanding of the present invention, the present invention is described in further detail below in conjunction with embodiment, but protection scope of the present invention is not limited to the scope that embodiment explains.
Experimental technique described in the following embodiment if no special instructions, is conventional method; Described reagent and material if no special instructions, all can obtain from commercial channels.
Employed probio mainly is made up of the mixture of bacillus subtilis B7348, lactic acid bacteria LP-11 and antibacterial metabolite thereof among the following embodiment.Wherein the quality of bacillus subtilis B7348 accounts for 80%, and viable bacteria content is 2 * 10 8The CFU/ gram, the quality of lactic acid bacteria LP-11 and antibacterial metabolite thereof accounts for 20%, and viable bacteria content is 2.2 * 10 8The CFU/ gram.
Composition and the preparation method of the functional feed of embodiment 1, control mastitis for milk cows
The functional feed of control mastitis for milk cows is made up of the raw material of following mass parts: probio 0.25, selected corn 40, wheat bran 10, decortication dregs of beans 8, maize alcohol lees 8, dephenolize cotton dregs 8, cotton dregs 7, inferior powder 4.75, calcium monohydrogen phosphate 4, stone flour 2, rumen-undegraded fat powder 2, sodium bicarbonate 1.2, magnesia 0.5, sodium chloride 0.5, yeast molasses 1.5, cow producing milk phase premix 1.5 and sodium sulphate 0.8.
Contain vitamin A 1150000.0IU, calciferol 50000.0IU, vitamin E 12450.0mg, copper 1370.0mg, iron 8884.0mg, zinc 8076.0mg, manganese 4084.0mg, iodine 4.0mg, selenium 48.0mg, cobalt 22.0mg in the above-mentioned per kilogram cow producing milk phase premix, surplus is carrier.
Processing technology:
The raw material of forming described mass parts is mixed, mixture is carried out modified (refining temperature is 40 ℃, 30 seconds time), granulates, namely obtain described control mastitis for milk cows functional feed.
Composition and the preparation method of the functional feed of embodiment 2, control mastitis for milk cows
The functional feed of control mastitis for milk cows is made up of the raw material of following mass parts: probio 0.3, selected corn 41, wheat bran 9, decortication dregs of beans 10.5, maize alcohol lees 7, dephenolize cotton dregs 8, cotton dregs 5, inferior powder 5.4, calcium monohydrogen phosphate 4, stone flour 2, rumen-undegraded fat powder 2, sodium bicarbonate 1.2, magnesia 0.5, salt 0.5, molasses powder 1.5, cow producing milk phase premix 1.5, sodium sulphate 0.8.
Contain vitamin A 1150000.0IU, calciferol 50000.0IU, vitamin E 12450.0mg, copper 1370.0mg, iron 8884.0mg, zinc 8076.0mg, manganese 4084.0mg, iodine 4.0mg, selenium 48.0mg, cobalt 22.0mg in the above-mentioned per kilogram cow producing milk phase premix, surplus is carrier.
The preparation method is with embodiment 1.
Composition and the preparation method of the functional feed of embodiment 3, control mastitis for milk cows
The functional feed of control mastitis for milk cows is made up of the raw material of following mass parts: probio 0.2, selected corn 42, decortication dregs of beans 12.5, wheat bran 8, maize alcohol lees 6, dephenolize cotton dregs 8, cotton dregs 4, inferior powder 4.8, calcium monohydrogen phosphate 4, stone flour 2, rumen-undegraded fat powder 2.5, sodium bicarbonate 1.2, magnesia 0.5, salt 0.5, molasses powder 1.5, cow producing milk phase premix 1.5, sodium sulphate 0.8.
Above-mentioned per kilogram cow producing milk phase premix contains vitamin A 1150000.0IU, vitamin D 250000.0IU, vitamin E 12450.0mg, copper 1370.0mg, iron 8884.0mg, zinc 8076.0mg, manganese 4084.0mg, iodine 4.0mg, selenium 48.0mg, cobalt 22.0mg, and surplus is carrier.
The preparation method is with embodiment 1.
The effect test of embodiment 4, control mastitis for milk cows functional feed (reducing the body cell test)
1, test material
Test group is the functional feed of the control mastitis for milk cows of embodiment 1 preparation; Control group does not just add probio, and other compositions and preparation technology are identical with the feed of embodiment 1.
2, test site: Shanghai milk group fragrant flower cattle farm.
3, the test period experimental period, be: on April 4,5 days to 2009 March in 2009.
4, selection and the grouping of test milk cow
Select the lactation of 50 health holstein cow in early stage or mid-term, be divided into 2 groups, test group and control group according to parity, body weight, lactation fate, principle pairing that daily yielding is close.The grouping situation is as shown in table 1.
Table 1 test milk cow grouping situation
Figure BDA0000121991720000041
5, feeding and management
The daily ration structure of test group and control group is consistent with the mode of feeding.Test branchs preliminary trial period and just trying the phase,, 4 days preliminary trial periods,, control group is pressed and is had feeding regime now, the test group test group daily ration of throwing something and feeding, and feed every day at twice.Just the examination phase is 30 days.Milk cow is loose housing, and three feedings are milked, freely drunk water for three times.(experimental stage is not changed the daily ration prescription, only reject the bigger ox of output fluctuation amplitude occurring in the process of the test, in the process of the test data of sick ox not at the row of statistics, avoid milk cow stress event take place)
6 testing index on-tests and end detect somatic number in the cow's milk respectively.
7 result of the tests
On April 4th, 2009, body cell detected: control group 750,000, test group 480,000.
Conclusion: the control group body cell descends 770,000-750,000=20,000
The test group body cell descends 790,000-480,000=210,000
Test group descends significantly than control group body cell.Show that functional feed provided by the invention can effectively prevent generation, the development of mastitis for milk cows.

Claims (6)

1. a functional feed of preventing and treating mastitis for milk cows is made up of the raw material of following mass parts: probio 0.2-0.5 part, corn 40-60 part, wheat bran 8-15 part, decortication dregs of beans 5-15 part, maize alcohol lees 5-10 part, dephenolize cotton dregs 5-15 part, cotton dregs 4-10 part, inferior powder 2-5 part, calcium monohydrogen phosphate 3-4 part, stone flour 1.5-2 part, rumen-undegraded fat powder 2-3 part, sodium bicarbonate 1.0-1.5 part, magnesia 0.5-1.0 part, sodium chloride 0.3-0.8 part, molasses 1-2 part, cow producing milk phase premix 1-1.5 part and sodium sulphate 0.5-1 part; Described probio is made up of bacillus subtilis B7348, lactic acid bacteria LP-11 and their antibacterial metabolite.
2. the functional feed of control mastitis for milk cows according to claim 1, it is characterized in that: contain retinol1 150000.0IU, calciferol 50000.0IU, vitamin e1 2450.0mg, copper 1370.0mg, iron 8884.0mg, zinc 8076.0mg, manganese 4084.0mg, iodine 4.0mg, selenium 48.0mg, cobalt 22.0mg in the described cow producing milk phase premix of per kilogram, surplus is carrier.
3. the functional feed of control mastitis for milk cows according to claim 1 and 2 is characterized in that: described molasses are the fermentation molasses.
4. the method for preparing the functional feed of arbitrary described control mastitis for milk cows among the claim 1-3, comprise the steps: each described raw material among the claim 1-3 is carried out weighing according to proportioning, pulverize then, mix, mixture is carried out modified, granulation, obtain feed granules.
5. method according to claim 4, it is characterized in that: described modified temperature is 40 ℃-70 ℃, and the modified time is 20s-60s.
6. reduce application in the product of the mastitis for milk cows incidence of disease according to the functional feed of each described control mastitis for milk cows among the claim 1-3 in preparation.
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CN102870994B (en) * 2012-10-11 2018-02-02 北京大北农科技集团股份有限公司 A kind of functional milks ox feed additive for preventing cow subclinical mastitis, reducing somatic number
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AU2014266266B2 (en) * 2013-05-17 2019-05-16 Asahi Biocycle Co., Ltd. Preventive or therapeutic agent for ruminant animal mastitis
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CN104187053A (en) * 2014-07-24 2014-12-10 宿州市草源牧业股份有限公司 Composite feed for preventing dairy cow mastitis
CN105166450A (en) * 2015-08-06 2015-12-23 钱峰 Dairy cow feed for preventing and treating mastitis and preparation method thereof
CN105104906A (en) * 2015-10-12 2015-12-02 陈薇 Feed for preventing and treating bovine subclinical mastitis and preparation method of feed
CN105255768A (en) * 2015-11-02 2016-01-20 石河子大学 Preparation method of lactobacillus special for milk
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CN108159395B (en) * 2018-01-18 2021-05-11 长沙绿叶生物科技有限公司 Preparation for preventing and treating cow foot and limb diseases and preparation method thereof
CN111543550A (en) * 2020-05-12 2020-08-18 肖鹏宏 Whole-daily-grain compound feed for dairy cow feeding without grass and preparation method thereof
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