CN102526551A - Effervescent traditional Chinese medicine composition for treating inappetence and preparation method thereof - Google Patents

Effervescent traditional Chinese medicine composition for treating inappetence and preparation method thereof Download PDF

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Publication number
CN102526551A
CN102526551A CN2010105814991A CN201010581499A CN102526551A CN 102526551 A CN102526551 A CN 102526551A CN 2010105814991 A CN2010105814991 A CN 2010105814991A CN 201010581499 A CN201010581499 A CN 201010581499A CN 102526551 A CN102526551 A CN 102526551A
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Prior art keywords
effervescent
chinese medicinal
medicinal composition
inappetence
parts
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CN2010105814991A
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Chinese (zh)
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陈庆忠
安同伟
尚晓迪
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Tianjin Rebate Science and Technology Development Co Ltd
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Tianjin Rebate Science and Technology Development Co Ltd
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Abstract

The invention relates to an effervescent traditional Chinese medicine composition with a function of treating inappetence. The traditional Chinese medicine composition comprises the following components in parts by weight: 30-50 parts of rough gentian, 10-30 parts of malt (colored), 10-30 parts of dried orange peel, 10-30 parts of hawthorn, 10-30 parts of effervescing agent and 5-20 parts of lubricant. The formula composition provided by the invention is scientific and reasonable, has quick effect-taking speed, high bioavailability, no toxic side effects or drug residue, lower production cost and convenience in use, and is a safe and reliable effervescent traditional Chinese medicine composition for treating inappetence.

Description

Effervescent Chinese medicinal composition of treatment inappetence and preparation method thereof
Technical field
The invention belongs to field of veterinary, especially a kind of effervescent Chinese medicinal composition of treating inappetence and preparation method thereof.
Background technology
Inappetence is one of disease common in the cattle breeding; Though there have been some to be directed against the medicine of domestic animal inappetence symptom on the market; But drug residue is insoluble problem always; Therefore countries in the world are problem demanding prompt solutions to China's livestock and poultry breeding industry all in the supervision that strengthens the residual problem of medicine.
Summary of the invention
The object of the present invention is to provide a kind of effervescent Chinese medicinal composition of treating inappetence, this Chinese medicine composition composition formula is formed scientific and reasonable, and onset is rapid, and bioavailability is high, has no side effect and drug residue, and production cost is lower, and is easy to use.
Another object of the present invention is to provide a kind of method for preparing of treating the effervescent Chinese medicinal composition of inappetence.
The present invention realizes through following technical scheme:
A kind of effervescent Chinese medicinal composition of treating inappetence, its Chinese medicinal composition and ratio of weight and number thereof are:
Radix Gentianae 30-50 part:
Fructus Hordei Germinatus (stir-fry) 10-30 part;
Pericarpium Citri Reticulatae 10-30 part;
Fructus Crataegi 10-30 part;
Effervescent 10-30 part;
Lubricant 5-20 part.
And described effervescent is combined by the wherein a kind of and sodium bicarbonate weight ratio in tartaric acid, citric acid, the adipic acid at 1: 1.
And described lubricant is wherein a kind of in sucralose, erythritol, magnesium stearate, the dodecyl sodium sulfate.
A kind of method for preparing of treating the effervescent Chinese medicinal composition of inappetence, the step of its preparation method is:
(1), takes by weighing Radix Gentianae, Fructus Hordei Germinatus (stir-fry), Pericarpium Citri Reticulatae, Fructus Crataegi decocte with water twice according to weight proportion, two hours first time, one hour for the second time; Collecting decoction filters, and it is 1.32~1.35 thick paste that filtrating is concentrated into relative density; Drying is pulverized the back all through 80 mesh sieves, obtains mixture A;
(2), according to weight proportion take by weighing effervescent, lubricant pulverize respectively the back all through the abundant mix homogeneously of mixture A in 80 mesh sieves and the step (1), obtain mixture B;
(3), be binding agent system soft material with mixture B with 50~60% alcoholic solution of 2~4%PVP; And with soft material all through 10~15 mesh sieve system granules; Under 50~60 ℃, carry out aeration-drying; All process granulate again, promptly obtain the effervescent Chinese medicinal composition of finished product treatment inappetence through 20~30 mesh sieves.
Advantage of the present invention and beneficial effect are:
In the effervescent Chinese medicinal composition of this treatment inappetence with Radix Gentianae, Fructus Hordei Germinatus (stir-fry), Pericarpium Citri Reticulatae, Fructus Crataegi as the natural Chinese medicine composition, have good heat clearing and damp drying, the effect of invigorating the stomach and promoting digestion.As the natural Chinese medicines extract, do not have any poisonous and harmful substance simultaneously, can not produce toxic and side effects, more can not exert an influence health to animal body.
2. the effervescent Chinese medicinal composition of this treatment inappetence is introduced the effervescent technology in the tablet of this medicine into cleverly, saves a large amount of manpower and materials, and the effective ingredient in the medicine is dissolved rapidly and uniformly; Being convenient to domestic animal absorbs; Improve bioavailability, can significantly improve the clinical efficacy of medicine, the effervescent The Application of Technology has been practiced thrift aquaculture cost; Only need in the domestic animal drinking water, to throw in to get final product, simplified operation.
3. the present invention fills a prescription and forms scientific and reasonablely, and onset is rapid, and bioavailability is high, has no side effect and drug residue, and production cost is lower, and is easy to use, is a kind of effervescent Chinese medicinal composition of safe and reliable treatment inappetence.
The specific embodiment
The present invention further details through following examples.Need to prove: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Radix Gentianae in the component of the present invention, Fructus Hordei Germinatus (stir-fry), Pericarpium Citri Reticulatae, Fructus Crataegi, tartaric acid, citric acid, adipic acid, sodium bicarbonate, sucralose, erythritol, magnesium stearate, dodecyl sodium sulfate all can be bought on market and obtain.
Embodiment 1
A kind of effervescent Chinese medicinal composition of treating inappetence, its Chinese medicinal composition and weight are respectively: Radix Gentianae 50Kg; Fructus Hordei Germinatus (stir-fry) 10Kg; Pericarpium Citri Reticulatae 10Kg; Fructus Crataegi 10Kg; Effervescent 20Kg; Lubricant 5Kg; Effervescent is made up of tartaric acid 10Kg and sodium bicarbonate 10Kg, and lubricant is a sucralose.
A kind of method for preparing of treating the effervescent Chinese medicinal composition of inappetence, the step of its preparation method is:
(1), takes by weighing Radix Gentianae, Fructus Hordei Germinatus (stir-fry), Pericarpium Citri Reticulatae, Fructus Crataegi decocte with water twice according to weight proportion, two hours first time, one hour for the second time; Collecting decoction filters, and it is 1.32 thick paste that filtrating is concentrated into relative density; Drying is pulverized the back all through 80 mesh sieves, obtains mixture A;
(2), according to weight proportion take by weighing effervescent, lubricant pulverize respectively the back all through the abundant mix homogeneously of mixture A in 80 mesh sieves and the step (1), obtain mixture B;
(3), be binding agent system soft material with mixture B with 50% alcoholic solution of 2%PVP; And with soft material all through 10 mesh sieve system granules; Under 50 ℃, carry out aeration-drying, all process granulate again, promptly obtain the effervescent Chinese medicinal composition of finished product treatment inappetence through 20 mesh sieves.
Embodiment 2
A kind of effervescent Chinese medicinal composition of treating inappetence, its Chinese medicinal composition and weight are respectively: Radix Gentianae 30Kg; Fructus Hordei Germinatus (stir-fry) 30Kg; Pericarpium Citri Reticulatae 10Kg; Fructus Crataegi 10Kg; Effervescent 15Kg; Lubricant 5Kg.And described effervescent is made up of citric acid 7.5Kg and sodium bicarbonate 7.5Kg.Lubricant is an erythritol.
A kind of method for preparing of treating the effervescent Chinese medicinal composition of inappetence, the step of its preparation method is:
(1), takes by weighing Radix Gentianae, Fructus Hordei Germinatus (stir-fry), Pericarpium Citri Reticulatae, Fructus Crataegi decocte with water twice according to weight proportion, two hours first time, one hour for the second time; Collecting decoction filters, and it is 1.35 thick paste that filtrating is concentrated into relative density; Drying is pulverized the back all through 80 mesh sieves, obtains mixture A;
(2), according to weight proportion take by weighing effervescent, lubricant pulverize respectively the back all through the abundant mix homogeneously of mixture A in 80 mesh sieves and the step (1), obtain mixture B;
(3), be binding agent system soft material with mixture B with 60% alcoholic solution of 4%PVP; And with soft material all through 15 mesh sieve system granules; Under 60 ℃, carry out aeration-drying, all process granulate again, promptly obtain the effervescent Chinese medicinal composition of finished product treatment inappetence through 30 mesh sieves.
Embodiment 3
A kind of effervescent Chinese medicinal composition of treating inappetence, its Chinese medicinal composition and weight are respectively: Radix Gentianae 30Kg; Fructus Hordei Germinatus (stir-fry) 10Kg; Pericarpium Citri Reticulatae 30Kg; Fructus Crataegi 10Kg; Effervescent 15Kg; Lubricant 5Kg.Effervescent is made up of adipic acid 7.5Kg and sodium bicarbonate 7.5Kg.Lubricant is a magnesium stearate.
The step of its preparation method is with embodiment 1.
Embodiment 4
A kind of effervescent Chinese medicinal composition of treating inappetence, its Chinese medicinal composition and weight are respectively: Radix Gentianae 30Kg; Fructus Hordei Germinatus (stir-fry) 10Kg; Pericarpium Citri Reticulatae 10Kg; Fructus Crataegi 30Kg; Effervescent 15Kg; Lubricant 5Kg.Effervescent is made up of adipic acid 7.5Kg and sodium bicarbonate 7.5Kg.Lubricant is a dodecyl sodium sulfate.
The step of its preparation method is with embodiment 1.
Embodiment 5
A kind of effervescent Chinese medicinal composition of treating inappetence, its Chinese medicinal composition and weight are respectively: Radix Gentianae 30Kg; Fructus Hordei Germinatus (stir-fry) 15Kg; Pericarpium Citri Reticulatae 15Kg; Fructus Crataegi 20Kg; Effervescent 15Kg; Lubricant 5Kg.Effervescent is made up of adipic acid 7.5Kg and sodium bicarbonate 7.5Kg.Lubricant is a dodecyl sodium sulfate.
The step of its preparation method is with embodiment 1.
The present invention does not need dissolving in advance, directly drops into and cultures in the domestic animal drinking water, and the per kilogram water body gets final product with this effervescent Chinese medicinal composition 1 gram-10 grams.
The clinical practice experiment
1, experimental technique:
Selection has 180 of the barren sows of inappetence symptom to be divided into two groups at random, and one group is adopted common Radix Gentianae sheet to treat, and one group is adopted the present invention to treat, every group of three repetitions, and each repeats 30 pigs, and the test period is 2 months, and result of the test is following:
Figure BSA00000381335700041
2, experimental result
The morbidity rehabilitation situation of testing with pig through the primary part observation record obtains the result, and therapeutic effect is obvious, adopts of the present invention group of cure rate 97.8%, than adopting common Radix Gentianae sheet group to improve 18.9%.

Claims (4)

1. effervescent Chinese medicinal composition of treating inappetence, it is characterized in that: this Chinese medicinal composition and ratio of weight and number thereof are:
Radix Gentianae 30-50 part:
Fructus Hordei Germinatus (stir-fry) 10-30 part;
Pericarpium Citri Reticulatae 10-30 part;
Fructus Crataegi 10-30 part;
Effervescent 10-30 part;
Lubricant 5-20 part.
2. the effervescent Chinese medicinal composition of treatment inappetence according to claim 1 is characterized in that: described effervescent is combined by the wherein a kind of and sodium bicarbonate weight ratio in tartaric acid, citric acid, the adipic acid at 1: 1.
3. the effervescent Chinese medicinal composition of treatment inappetence according to claim 1 is characterized in that: described lubricant is wherein a kind of in sucralose, erythritol, magnesium stearate, the dodecyl sodium sulfate.
4. the method for preparing of the effervescent Chinese medicinal composition of a treatment inappetence as claimed in claim 1, it is characterized in that: the step of this method for preparing is:
(1), takes by weighing Radix Gentianae, Fructus Hordei Germinatus (stir-fry), Pericarpium Citri Reticulatae, Fructus Crataegi decocte with water twice according to weight proportion, two hours first time, one hour for the second time; Collecting decoction filters, and it is 1.32~1.35 thick paste that filtrating is concentrated into relative density; Drying is pulverized the back all through 80 mesh sieves, obtains mixture A;
(2), according to weight proportion take by weighing effervescent, lubricant pulverize respectively the back all through the abundant mix homogeneously of mixture A in 80 mesh sieves and the step (1), obtain mixture B;
(3), be binding agent system soft material with mixture B with 50~60% alcoholic solution of 2~4%PVP; And with soft material all through 10~15 mesh sieve system granules; Under 50~60 ℃, carry out aeration-drying; All process granulate again, promptly obtain the effervescent Chinese medicinal composition of finished product treatment inappetence through 20~30 mesh sieves.
CN2010105814991A 2010-12-09 2010-12-09 Effervescent traditional Chinese medicine composition for treating inappetence and preparation method thereof Pending CN102526551A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103315361A (en) * 2013-07-15 2013-09-25 于法周 Processing method for haw electuary
CN104705762A (en) * 2015-03-07 2015-06-17 湖北卫尔康现代中药有限公司 Plum juice effervescent tablet

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
赵吉刚: "中西医结合治疗猪便秘的疗效观察", 《上海畜牧兽医通讯》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103315361A (en) * 2013-07-15 2013-09-25 于法周 Processing method for haw electuary
CN103315361B (en) * 2013-07-15 2014-10-08 于法周 Processing method for haw electuary
CN104705762A (en) * 2015-03-07 2015-06-17 湖北卫尔康现代中药有限公司 Plum juice effervescent tablet

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Application publication date: 20120704