CN102526467A - Chinese medicinal composition for treating pulmonary fungal infection and preparation method thereof - Google Patents
Chinese medicinal composition for treating pulmonary fungal infection and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal composition for treating pulmonary fungal infection. The Chinese medicinal composition consists of honeysuckle flower, weeping forsythia, heartleaf houttuynia herb, giant knotweed, great burdock achene, lepidium seed, blackberry lily, thunberg fritillary bulb, perilla seed, astragalus, divaricate saposhnikovia root, large-head atractylodes rhizome, dwarf lilyturf root, straight ladybell root, coptis root, baikal skullcap root and liquoric root. The Chinese medicinal composition has the anti-inflammatory and anti-infection effects of clearing away heat and toxic materials, preventing phlegm from forming, stopping coughing, expelling pathogenic factors, supplementing qi, nourishing yin, strengthening body resistance, eliminating evil and the like, so that patients suffering from radiation treatment, chemo-treatment, aging and body weakness can rapidly recover normal physiological functions of the lungs of human bodies. According to clinical application of the Chinese medicinal composition to patients suffering from pulmonary fungal infection, uncomfortable symptoms such as cough, spitting of frothy sputum, chest distress, shortness of breath, fever, aversion to cold, stuffy nose, throat itching and the like can be relieved remarkably, the treatment course is shortened, impairment is reduced, and the curative effect is remarkable.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of Chinese medicine composition of treating Pulmonary Fungal Infections and preparation method thereof.
Background technology
Over nearly 20 years; HIV infection, blood system malignant tumor, hematopoietic stem cell or entity organ transplantation, use vivo inserted, the indwelling etc. of immunosuppressant treatment autoimmune disease and various conduits to cause that Pulmonary Fungal Infections (Pulmonary fungal infection) sickness rate significantly increases; Wherein with Bronchio-pulmonary candidiasis, pulmonary aspergillosis, pulmonary cryptococosis, pulmonary mucormycosis, lung pityrosporion ovale disease etc. are the most common.Because the host is in immunosuppressive condition, the common insidious onset of patient's Pulmonary Fungal Infections causes the diagnosis of this type disease and treatment comparatively difficult.Doctor trained in Western medicine is generally taked the means of antifungal therapy to this type of patient at present; And that this treatment means often has a fungicidal spectrum is narrower; Drug resistance and obvious toxic and side effects and fail to reach satisfied curative effect become primary disease and cause one of cause of death of organ transplant recipients, malignant hematologic disease and malignant tumor patient and other critical illnesses patient.
Chinese medicine does not have the name of disease of Pulmonary Fungal Infections, but belongs to diseases caused by exogenous pathogenic factor according to clinical manifestation and site of pathological change, endogenous cough's category.The traditional Chinese medical science is thought lung governing qi, and department breathes, on connect air flue, throat is had one's ideas straightened out in nose, closes fur outward, interior be the canopy of the vital organs of the human body, its gas passes through hundred arteries and veins and logical he is dirty, cold-resistant heat is " it is dirty to spoil " so claim lung again, is subject to that inside and outside pathogen is attacked and is disease.Pneumonopathy a surname then falls not normal, and abnormal rising of lung-QI is sent out and is cough.Therefore, no matter the cough due to diseases caused by exogenous pathogenic factor or the internal injury all belongs to lung system and receives disease, says like " Jing Yue's complete work cough " piece of writing: " though cough demonstrate,prove many, pneumonopathy nothing but "." three-character medical verses cough " piece of writing: " lung is the canopy of internal organs, and that exhales is then empty, suctions then full, only receive the healthy energy of naturalness; must not receive external courteous, courteous dried then choking and coughing, only receive the clearing heat in QI system of internal organs; must not receive the pathogenic QI in the body of internal organs, pathogenic QI in the body is done it, also chokes and coughs "; " Medicine Comprehended ": " the lung body belongs to gold; such as Zhong Ran, Zhong Fei kowtows and do not ring, and the pathogen of wind and cold heat-damp in summer dryness-fire six climate exopathogens is from the then ring of hitting outward; labor desire feelings will diet process rich fire from the then also ring of hitting ", pointing out to cough is that a kind of pathologic that inside and outside pathogenic factor is produced when violating is reacted.
Adopting motherland's theory of medicine, carry out Chinese medicine, is the characteristic and the advantage of China's Pulmonary Fungal Infections disease treatment.Think according to TCM Document is said: the cause of disease of Pulmonary Fungal Infections is the pathogen of affection of exogenous wind-cold heat-damp in summer dryness-fire six climate exopathogens, due to the internal injury vital organs of the human body negative and positive of qi and blood, and particularly radiotherapy, the patient of chemotherapy; Because of disease own and side effects of pharmaceutical drugs, at first cause the damage of viscera, resistance against diseases weakens, and very easily is the exopathogen invasion and attack, because of lung be " it is dirty to spoil "; Department breathes, and closes fur outward, the exopathogen invasion and attack; Stand in the breach, as Ye Xiangyan " diseases caused by exogenous pathogenic factor are warm " piece: " warm pathogen tend to attack the upper orifices, attacking the lung first ".Diseases such as the cough that occurs when fungus causes pulmonary infection, in the traditional Chinese medical science, its cause of disease is due to weakened body resistance pathogen is attacked; Pathogenesis is: abnormal rising of lung-QI, a surname falls not normal.Remove if only set upright then the pathogen difficulty, if only eliminating evil not only disease can not be removed, it is deeply evil to be prone on the contrary cause a disease, and increases the weight of the state of an illness.Adopt the relevant report of therapy of combining Chinese and Western medicine pulmonary infection fungal infection also to have following deficiency at present: 1, not standardization of medicine, each cures house makes the medicament custom become to vary with drug group; 2, clinical observation on the therapeutic effect often lacks experimental basis to medicine in the concrete pharmacology mechanism of body, but lacks generalization.
Summary of the invention
The technical problem that the present invention will solve provides a kind of Chinese medicine composition with supplementing QI and nourishing YIN, heat-clearing and toxic substances removing cough suppressing effect and preparation method thereof for to the western medicine poor effect that exists in the western medical treatment of present Pulmonary Fungal Infections and the shortcoming of obvious toxic-side effects.
For solving the problems of the technologies described above, technical scheme provided by the invention is:
A kind of Chinese medicine composition of treating Pulmonary Fungal Infections, contained active component is prepared from following raw materials according by weight ratio: 8～32 parts of Flos Lonicerae, 8～32 parts of Fructus Forsythiaes, 8～32 parts of Herba Houttuyniae, 8～32 parts of Rhizoma Polygoni Cuspidati, 8～15 parts of Fructus Arctiis, 8～15 parts of Semen Lepidii (Semen Descurainiae)s, 8～15 parts of Rhizoma Belamcandae, 8～20 parts of Bulbus Fritillariae Thunbergiis, 8～15 parts of Fructus Perillaes, 20～32 parts of the Radixs Astragali, windproof 8～15 parts, 8～20 parts of the Rhizoma Atractylodis Macrocephalaes, 8～20 parts of Radix Ophiopogonis, 15～32 parts of Radix Adenophorae (Radix Glehniae), 8～15 parts of Rhizoma Coptidis, 10～15 parts of Radix Scutellariaes, 5～12 parts in Radix Glycyrrhizae.
The present invention also provides the method for preparing of this Chinese medicine composition:
Step 1) takes by weighing the medical material of respectively distinguishing the flavor of by said weight portion proportioning, and crude drug is mixed, pulverizes;
Step 2) under the room temperature above-mentioned raw materials medicine is flooded 3 times in extracting solvent, said crude drug is 1: 1.5～4 with the part by weight that extracts solvent, stirs, and filters, and taking liquid is subsequent use;
Step 3) merges three dipping medicinal liquids that above-mentioned steps obtains and concentrates, dry behind the extractum, promptly get.
In Chinese medicine composition of the present invention, Flos Lonicerae, Fructus Forsythiae, Herba Houttuyniae, Rhizoma Polygoni Cuspidati, Fructus Arctii, Rhizoma Belamcandae, Semen Lepidii (Semen Descurainiae), Bulbus Fritillariae Thunbergii, as monarch drug, heat-clearing and toxic substances removing, preventing phlegm from forming and stopping coughing, eliminating evil going out; The Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Adenophorae share supplementing QI and nourishing YIN Radix Ophiopogonis, and shared is ministerial drug, the resistance against diseases of enhances human body; Rhizoma Coptidis, Radix Scutellariae, heat clearing and damp drying, assistant monarch drug heat-clearing and toxic substances removing, the assistant ministerial drug is to give birth to the source of expectorant extremely; Windproof assistant monarch drug is walked table and is dispeled the wind, and imperial ailment said due to cold or exposure; The gas of superinverse can fall in Fructus Perillae assistant ministerial drug, and holding concurrently can expectorant.Radix Glycyrrhizae is a messenger drug, can be in harmonious proportion each medicine of full side, and can play the effect of QI invigorating antidotal.
Flos Lonicerae is called Flos Lonicerae, Flos Lonicerae, plants the alabastrum of Radix Ophiopogonis Lonicera japonice Taponica Thunb for the perennial half evergreen prehensile woody climber of Caprifoliaceae.Alabastrum contains luteolin and glycoside thereof, also contains inositol, Saponin tannin etc.Decoct and pure immersion be in vitro to staphylococcus aureus, Hemolytic streptococcus, and streptococcus pneumoniae, meningococcus, typhoid fever, dysentery and Bacillus tuberculosis and leptospira equalization have inhibitory action, and external all have the resisiting influenza virus effect with in vivo test.Nature and flavor are sweet, cold.Return lung, stomach, large intestine channel.Have effects such as heat-clearing and toxic substances removing.Like Compendium of Material Medica: control " all rheumatism gas, and all toxic swellings, carbuncle, scabies, all malignant boil of poplar poison "; " Chongqing hall random notes ": " wind-fire excess-heat in the clear network." be used for anemopyretic cold, epidemic febrile disease initial stage, laryngopharynx swelling and pain, acute conjunctivitis, lobar pneumonia, dysentery, epidemic encephalitis type B leptospirosis etc.
Fructus Forsythiae, the another name Fructus Forsythiae is the fruit of Oleaceae plant Fructus Forsythiae (Forsythia suspenss (Thunb)).Contain forsythol, sterol compound, Saponin etc., decoct has inhibitory action external to equalizations such as staphylococcus aureus, streptococcus, streptococcus pneumoniae, diphtheria corynebacteriums.The water logging agent also can suppress the commonly encountered diseases dermatophytes, and injection has blood pressure lowering, diuresis and anti-inflammatory efficacy to animal.Nature and flavor are bitter, are slightly cold, and go into the heart, gallbladder meridian.Has heat-clearing and toxic substances removing, the effect of detumescence and apocenosis." Japan hanako materia medica ": " logical small intestinal, furuncle is controlled in evacuation of pus, pain relieving, logical menstruation "; " herbal classic ": " main cold and heat ".Be used for anemopyretic cold, laryngopharynx swelling and pain, macule, sore swollen toxin, scrofula, erysipelas, diseases such as pyretic stranguria.
Rhizoma Polygoni Cuspidati, another name speckle cane is polygonaceae plant Rhizoma Polygoni Cuspidati (Polygon-um cuspidatum Sieb, et Zucc) rhizome.Contain emodin, physcione, chrysophanol, Polydatin etc.Decoct has inhibitory action external to staphylococcus aureus, green pus, typhoid fever and shigella flexneri etc., and Polydatin ability antitussive brings high blood pressure down, and the expansion coronary vasodilator increases coronary flow, slightly strengthens the contraction of heart.Nature and flavor are bitter, acid, cold.Go into Liver Channel, have clearing away heat-damp and promoting diuresis, effects such as promoting blood circulation and detoxication.Be used for jaundice, cholelithiasis, bronchitis, pneumonia, rheumatic arthritis, stranguria with turbid discharge cholelithiasis, bronchitis, pneumonia, rheumatic arthritis, diseases such as stranguria with turbid discharge.
Herba Houttuyniae, the another name Herba Houttuyniae is the herb of saururaceae plant houttuynia cordata (Houttuynia cordata Thunb).Contain volatile oil, main component is a houttuynine sodium bisulfite, and to staphylococcus aureus, streptococcus pneumoniae and large intestine, dysentery, Bacillus typhi all have inhibitory action external.Decoct has inhibitory action to some strain of influenza virus, and mice is had antitussive action.Nature and flavor are hot, are slightly cold.Go into lung, large intestine channel.Has heat-clearing and toxic substances removing, effects such as diuresis." Bencao Jingshu ": " control phlegm-heat obstructing in the lung, send out and to be the key medicine of lung abscess vomiting bloody pus." these article are usually used in treating diseases such as lung abscess, pneumonia, pertussis, urinary tract infection.
Rhizoma Belamcandae is called flat bamboo, crow fan, Herba Iridis japonicae.Be irides Rhizoma Belamcandae (Belamcanda chinensis (L) DC) rhizome.Contain belamcandin, shekanin, tectorigenin etc.Decoct or preserved material can suppress common pathogenic dermatophytes and echovirus and herpes virus in external high concentration, and shekanin, tectorigenin have antiinflammatory action.Nature and flavor are bitter, and are cold.Return lung meridian.Has eliminating fire and detoxication, sore-throat relieving expectorant, effects such as dissipating blood stasis.Be usually used in laryngopharynx swelling and pain, the card of breathing with cough of productive cough intenseness of heat.Like " herbal classic ": " control cough with dyspnea, the sore throat pharyngalgia must not message, eliminating stagnation gas.”
Fructus Arctii, another name FRUCTUS ARCTII, Fructus Arctii, evil are in fact.Mature seed for herbaceos perennial Fructus Arctii (Arctium lappa L).Contain arctigenin, isoarctigenin etc.Decoct has inhibitory action external to staphylococcus aureus, and the water logging agent has inhibitory action to multiple pathomycete.Nature and flavor are hot, and hardship is cold.Into lung, the stomach warp.Has dispelling wind, rash, sore-throat relieving, effects such as detumescence.Be usually used in anemopyretic cold, cough, rash goes out not smooth, laryngopharynx swelling and pain, cards such as heat in blood constipation.
Windproof, another name RADIX SAPOSHINOKOVIAE from Northeast, RADIX LEDEBOURIELLAE are the root of umbelliferae Saposhnikovia divaricata (Ledeboufiella divrata (Benth et Hookf) Hiroe).Contain volatile oil, mannitol, bitterness glycoside etc.Nature and flavor are hot, sweet tepor.Go into bladder, liver, spleen channel.Have and deliver, dispel the wind, win and wet, effects such as pain relieving." book on Chinese herbal medicine converge with speech ": " typhoid fever from the beginning of, sick Taiyang channel is had a headache and fever, general pain is lossless, or cough, the nose dry pharynx of tremble with fear, with windproof hot temperature, light loosing, it is not dry to moisten, and can send out heresy and go out from the hair key." these article are usually used in anemofrigid cold, headache and dizziness, anemofrigid-damp arthralgia, joint is ached, diseases such as tetanus.
The Radix Astragali, Gu is made Radix Astragali, is the root of the leguminous plant Radix Astragali (Astr-galus membraceus (Fisch) Bun-ge) or astragalus mongholicus Bge (AmongholicusBunge).Contain choline, betanin, coumarin, chromocor compound, Saponin, aminoacid etc.Nature and flavor are sweet, tepor.Go into lung, spleen channel.Has invigorating the spleen and replenishing QI, consolidating superficial resistance, diuretic, holder skin ulcer, effects such as granulation promoting.Like " not Lu ": " it be deficient to mend the husband, the five kinds of over strain weakness and emaciation.Quench the thirst stomachache, dysentery, QI invigorating " " pearl sac ": " the sweet Wen Chunyang of the Radix Astragali, it is with having five: mend all empty deficiencies, one also; Benefit vigour, two also; Strong taste, three; Go flesh heat, four also; The evacuation of pus pain relieving is invigorated blood circulation, hemopoietic, and the expelling the toxic substance from the body with tonic carbuncle of yin nature is persons particularly liable to develop skin infection's panacea." these article are usually used in weakness of the spleen and stomach, the lack of appetite asthenia, deficiency of vital energy blood prostration, metrorrhagia, leukorrhagia, the chronic diarrhea proctoptosis, uterine prolapse, gastroptosis, the exterior deficiency spontaneous perspiration, night sweat, deficiency of vital energy edema, chronic nephritis, carbuncle not diabrosis is for a long time burst and disease such as is not held back for a long time.
The Rhizoma Atractylodis Macrocephalae is the feverfew Rhizoma Atractylodis Macrocephalae (Atractylodes ma-crocephalz) rhizome.Contain volatile oil, main component is atractylol, atractylone, vitamin etc., and decoct is to Canis familiaris L., and rat, rabbit have diuresis, can promote the particularly drainage of sodium of electrolyte, and potassium is drained also to be increased, and have strong, protect the liver, increase effect to albumin and anticoagulant.For chemotherapy, or the leukocyte decline that actinotherapy causes has the effect that makes its rising, Rhizoma Atractylodis Macrocephalae oil that calmness and mitigation gastrointestinal peristalsis effect are arranged.Nature and flavor are bitter, and are sweet, tepor.Go into the taste warp.Have spleen invigorating and in, dampness, diuretic, hidroschesis, effect such as antiabortive.Like " pearl sac ": " expectorant is relieved oedema or abdominal distension through diuresis or purgation, promoting the production of body fluid to quench thirst for dehumidifying QI invigorating, invigorating middle warmer YANG invigorating ... the antiabortive heat clearing away of assistant Radix Scutellariae." " herbal classic ": " the hidroschesis heat extraction helps digestion "." not Lu ": " expectorant water, it be swollen to allowance for bark an edema due to wind pathogen knot." be usually used in insufficiency of the spleen lack of appetite, dyspepsia, deficiency-distension is had loose bowels, phlegm retention, edema, cards such as frequent fetal movement.
Radix Adenophorae (Radix Glehniae), another name bubble Radix Adenophorae (Radix Glehniae), RADIX ADENOPHORAE.Be campanulaceae plant wheel Radix Adenophorae (Radix Glehniae) (Adenophoratetahyiia (Thunb) Fish), or the root of Folium Pruni Radix Adenophorae (Radix Glehniae) (A.axtrlliun Borb) etc.The root of Folium Pruni Radix Adenophorae (Radix Glehniae) contains xanthotoxin, and the adenophora tetraphylla decoct has phlegm-dispelling functions to rabbit, and Radix Adenophorae (Radix Glehniae) immersion agent has bright cardiotonic to the Bufo siccus heart that exsomatizes.Nature and flavor are sweet, go into lung, stomach warp.Have clearing away lung-heat, support lung yin, effects such as expelling phlegm for arresting cough, like Compendium of Material Medica: " the lung moderate heat that disappears is controlled the chronic cough consumptive lung disease." " herbal classic ": " main accumulation of blood is shied gas, removes cold and heat, invigorating middle warmer, lung benefiting gas." be usually used in the cough due to lung-heat, the not umbrella of coughing up phlegm, dryness of the mouth and throat, pertussis, cards such as toothache caused by fire of deficiency type.
Radix Ophiopogonis, another name Radix Ophiopogonis, Radix Ophiopogonis.Be liliaceous plant dwarf lilyturf (Ophiopogonjaponieusaker-Gawl) tuber.Contain multiple careless glycoside, it is liquor-saturated with chrysanthemum grape glucoside, stigmasterol etc. also to contain β-paddy steroid.Injection is to the white mice hypoxia-bearing capability that is significantly improved.Nature and flavor are sweet, and little hardship is cold.Go into the heart, lung, stomach warp.Has clearing away heart-fire and moistening the lung, effects such as YIN nourishing and the production of body fluid promoting.Like " not Lu ": " treat the asthenia exopathogenic heat, the xerostomia excessive thirst ... protect refreshingly, decide lung qi, settling five organs." " property of medicine opinion ": " main lung qi cough with dyspnea, it is short anxious to pant, logical kidney." " pearl sac ": " controlling the lung fire second of the three ten-day periods of the hot season ".It is vexed to be usually used in calentura, and Tianjin wound is thirsty, dryness of the lung dry cough, and spitting of blood, epistaxis, carbuncle furuncle and phyma poison is quenched one's thirst, and the dryness of the intestine constipation was tried out in treating coronary heart disease etc. modern age.
Bulbus Fritillariae Thunbergii, another name Bulbus Fritillariae Thunbergii, Bulbus Fritillariae Thunbergii.Bulb for liliaceous plant Bulbus Fritillariae Thunbergii (Fritillar vertillata Willdvar, thunbergii Bak).Contain peimine, peiminine, peimine glycoside etc.Peimine and peiminine have antitussive effect to white mice, during the peimine low concentration cat, rabbit bronchial smooth muscle are had dilating effect.Nature and flavor are bitter, and are cold.Go into lung, the heart, stomach warp.Has clearing heat, eliminating phlegm, relieving cough, effects such as powder detoxifcation.Like " book on Chinese herbal medicine can compile ": control " cough due to consumptive disease, the spitting of blood of spitting blood, lung abscess consumptive lung disease." be usually used in treating anemopyretic cold, laryngopharynx swelling and pain, cough due to lung-heat, abundant expectoration, lung abscess, stomach, duodenal ulcer, scrofula goiter, carbuncle furuncle and phyma poison etc.
Semen Lepidii (Semen Descurainiae) is crucifer Lepidium sativum L. (Lepi_dium apetalum Willdak) or bird's-pepper (pl. bird's-peppers) (L, virgincum L), the seed of descurainia sophia (l.) webb ex prantl (Descurania (L) Webb).Contain the Lepidium sativum L. seed and contain potassium myronate and cardiotonic glycoside etc., descurainia sophia seed contains volatile oil, and cardiotonic glycoside etc., alcohol extract are the effect of cardiotonic glycoside appearance in animal experiment, can strengthen myocardial contraction, decreased heart rate.Heavy dose can be drawn tachycardia, ventricular fibrillation etc.Nature and flavor are hot, and hardship is cold.Go into lung, urinary bladder channel.These article have eliminating the pathogens from the lung row water, effects such as eliminating phlegm relieving asthma.Like " property of medicine opinion ": " treat lung and stop up and go up the gas cough, Zhichuan is short, removes phlegm retention in the heart ".Be usually used in treating cough and asthma, sputum is stopped up lung, the edema of the face, cards such as breast abdomen hydrops dysuria.
Fructus Perillae, another name Fructus Perillae, FRUCTUS PERILLAE.Fruit for labiate wrinkle Folium Perillae (Perillascens (L) Britt var crspa (Thund) Hand-Mazz) or sharp Folium Perillae (P, frutescns (L) Brittvar acuta (Thunb) Budo) etc.The fatty oil of seed, vitamin B1.Nature and flavor are hot, temperature.Go into lung, large intestine channel.Have the sending down the abnormal ascending QI expectorant, the loosening bowel to relieve constipation relieving cough and asthma, effects such as the wide intestinal of sharp diaphragm are like " Japan hanako materia medica ": " cough-relieving, the profit heart, lung, eliminating phlegm-retention ".Be usually used in cough with dyspnea, phlegm dyspnea, uncomfortable in chest, cards such as constipation.
Assistant monarch drug heat-clearing and toxic substances removing, the assistant ministerial drug is to give birth to the source of expectorant extremely.
Radix Scutellariae is the root of Labiatae herbaceos perennial Radix Scutellariae (Scutellariabai-calensis Gcoroi).Contain baicaligenin, baicalin, wogonin, wogonoside and neobaicalein etc.Decoct external to staphylococcus, streptococcus, streptococcus pneumoniae; Meningococcus, dysentery, diphtheria; Green pus and tubercule bacillus all have inhibitory action; Various skin fungus and leptospira are also had inhibitory action, the white mice of influenza virus is had the certain protection effect, decoct, tincture and yellow glycoside all have hypotensive effect to anesthetized dog, cat, rabbit.In addition, Radix Scutellariae also has the effect of function of gallbladder promoting, releasing smooth muscle spasm.Nature and flavor are bitter, and are cold.Go into gallbladder, stomach, large intestine channel, heart channel.These article have, the clearing away heat-fire detoxifcation, and except that damp and hot, hemostasis, antiabortive, control effects such as excessive thirst.Like Compendium of Material Medica: " control wind heat, damp and hot, headache, renal mass, cough caused by pathogenic fire consumptive lung disease, larynx raw meat, all losing blood." " not Lu ": " treating expectorant heat, pathogenic heat in the stomach " etc.Be usually used in hygropyrexia, jaundice, cards such as carbuncle sore tumefacting virus.
Rhizoma Coptidis, the another name Rhizoma Coptidis.Be perennial buttercup plant Rhizoma Coptidis (Cop-tis chinesis Frinch) and sibling species plant rhizome thereof.Contain berberine, 13-methyl-.psi.-coptisine. etc.In vitro tests proof Rhizoma Coptidis or berberine be to Hemolytic streptococcus, meningococcus, and Diplococcus pneumoniae, golden staphylococci, and Shi Shi dysentery bacterium etc. has stronger inhibition bacterium effect; Also effective to bacillus such as will Hayes and Fu Shi dysentery, pertussis, the plagues; To sick fungus, leptospira, ameba, infusorian etc. also have inhibitory action.Single develop immunity to drugs with being prone to.Nature and flavor are bitter, and are cold.Go into the heart, liver, stomach, large intestine channel.Go into heart channel.These article have heat clearing and damp drying, effects such as eliminating fire and detoxication.Like " pearl sac ": " it is with having six: the dirty fire of removing pathogen in the heart, and one also; Remove damp-heat in middle-JIAO, two also; All skin ulcers must be used, and three also; Curing rheumatism, four also; Go acute conjunctivitis to break out, five also, ends the middle part and see blood, and six also." be usually used in treating aphtha, laryngopharynx swelling and pain, carbuncle sore tumefacting virus, the furunculosis inside fire attack, knowledge swells and ache, the stomachache due to gastrointestinal is damp and hot, dysentery, vomiting; Calentura intenseness of heat heated, high fever, dry tired, even disease such as unconsciousness and delirium.
Radix Glycyrrhizae, the another name Radix Glycyrrhizae.Be glycyrrhizic legume (Clycyrhiza rlensisu Fiscs) rhizome.Contain glycyrrhizic acid, enoxolone.Extractum has protective effect to the rat experiment gastric ulcer, and decoct can suppress intestine in vitro.Extractum, glycyrrhizin, enoxolone have edema, the hypertension that promotes sodium, water retention effect and cause.Enoxolone has antiinflammatory action, and glycyrrhizin has anti-allergic effects.Radix Glycyrrhizae tool antitussive effect, the rats'liver infringement that carbon tetrachloride is caused has protective effect.Extractum and glycyrrhizin have certain Detoxication to some poisonous substance; The latter can reduce cholesterolemia and increase bile secretion.Nature and flavor are sweet, and are flat.Go into spleen, lung meridian.These article have the spleen reinforcing stomach function regulating, relieving spasm to stop pain, expelling phlegm for arresting cough, detoxifcation, the effect of coordinating the actions of various ingredients in a prescription.Be usually used in weakness of the spleen and stomach, epigastric pain, cough cardiopalmus, laryngopharynx swelling and pain, skin infection, cards such as poisoning.Also be used to treat hypocorticoidism disease modern age.
According to the effect and the drug effect of each flavor medicine, Chinese medicine composition prescription proportioning provided by the invention is: 8～32 parts of Flos Lonicerae, 8～32 parts of Fructus Forsythiaes, 8～32 parts of Herba Houttuyniae, 8～32 parts of Rhizoma Polygoni Cuspidati, 8～15 parts of Fructus Arctiis, 8～15 parts of Semen Lepidii (Semen Descurainiae)s, 8～15 parts of Rhizoma Belamcandae, 8～20 parts of Bulbus Fritillariae Thunbergiis, 8～15 parts of Fructus Perillaes, 20～32 parts of the Radixs Astragali, windproof 8～15 parts, 8～20 parts of the Rhizoma Atractylodis Macrocephalaes, 8～20 parts of Radix Ophiopogonis, 15～32 parts of Radix Adenophorae (Radix Glehniae), 8～15 parts of Rhizoma Coptidis, 10～15 parts of Radix Scutellariaes, 5～12 parts in Radix Glycyrrhizae.
As preferably, Chinese medicine composition prescription proportioning provided by the invention is: 10～30 parts of Flos Lonicerae, 10～30 parts of Fructus Forsythiaes, 10～30 parts of Herba Houttuyniae, 10～30 parts of Rhizoma Polygoni Cuspidati, 10～15 parts of Fructus Arctiis, 10～12 parts of Semen Lepidii (Semen Descurainiae)s, 10～15 parts of Rhizoma Belamcandae, 10～20 parts of Bulbus Fritillariae Thunbergiis, 10～15 parts of Fructus Perillaes, 20～30 parts of the Radixs Astragali, windproof 10～15 parts, 10～20 parts of the Rhizoma Atractylodis Macrocephalaes, 10～20 parts of Radix Ophiopogonis, 15～30 parts of Radix Adenophorae (Radix Glehniae), 10～12 parts of Rhizoma Coptidis, 12～15 parts of Radix Scutellariaes, 5～10 parts in Radix Glycyrrhizae.
More preferably, Chinese medicine composition prescription proportioning provided by the invention is: 30 parts of Flos Lonicerae, 30 parts of Fructus Forsythiaes, 30 parts of Herba Houttuyniae, 30 parts of Rhizoma Polygoni Cuspidati, 15 parts of Fructus Arctiis, 12 parts of Semen Lepidii (Semen Descurainiae)s, 15 parts of Rhizoma Belamcandae, 20 parts of Bulbus Fritillariae Thunbergiis, 15 parts of Fructus Perillaes, 30 parts of the Radixs Astragali, windproof 15 parts, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts of Radix Ophiopogonis, 30 parts of Radix Adenophorae (Radix Glehniae), 12 parts of Rhizoma Coptidis, 15 parts of Radix Scutellariaes, 10 parts in Radix Glycyrrhizae.
The present invention also provides the method for preparing of this Chinese medicine composition, and its process is:
Step 1) takes by weighing the medical material of respectively distinguishing the flavor of by said weight portion proportioning, and crude drug is mixed, pulverizes;
Step 2) under the room temperature above-mentioned raw materials medicine is flooded 3 times in extracting solvent, said crude drug is 1: 1.5～4 with the part by weight that extracts solvent, stirs, and filters, and taking liquid is subsequent use;
Step 3) merges three dipping medicinal liquids that above-mentioned steps obtains and concentrates, dry behind the extractum, promptly get.
As preferably, step 2) extracting solvent described in is 60% ethanol.
The adoptable dosage form of Chinese medicine composition of the present invention is oral solutions, tablet, powder, capsule, pill or granule.
The specific embodiment
The invention discloses a kind of Chinese medicine composition of treating Pulmonary Fungal Infections and preparation method thereof, those skilled in the art can use for reference this paper content, suitably improve technological parameter and realize.Special needs to be pointed out is that all similarly replace and change apparent to those skilled in the art, they all are regarded as and are included in the present invention.Method of the present invention and application are described through preferred embodiment; The related personnel obviously can change or suitably change and combination methods and applications as herein described in not breaking away from content of the present invention, spirit and scope, realizes and use technology of the present invention.
Technical scheme provided by the invention is:
A kind of Chinese medicine composition of treating Pulmonary Fungal Infections, contained active component is prepared from following raw materials according by weight ratio: 8～32 parts of Flos Lonicerae, 8～32 parts of Fructus Forsythiaes, 8～32 parts of Herba Houttuyniae, 8～32 parts of Rhizoma Polygoni Cuspidati, 8～15 parts of Fructus Arctiis, 8～15 parts of Semen Lepidii (Semen Descurainiae)s, 8～15 parts of Rhizoma Belamcandae, 8～20 parts of Bulbus Fritillariae Thunbergiis, 8～15 parts of Fructus Perillaes, 20～32 parts of the Radixs Astragali, windproof 8～15 parts, 8～20 parts of the Rhizoma Atractylodis Macrocephalaes, 8～20 parts of Radix Ophiopogonis, 15～32 parts of Radix Adenophorae (Radix Glehniae), 8～15 parts of Rhizoma Coptidis, 10～15 parts of Radix Scutellariaes, 5～12 parts in Radix Glycyrrhizae.
The method for preparing of this Chinese medicine composition provided by the invention:
Step 1) takes by weighing the medical material of respectively distinguishing the flavor of by said weight portion proportioning, and crude drug is mixed, pulverizes;
Step 2) under the room temperature above-mentioned raw materials medicine was flooded 3 days in extracting solvent, said crude drug is 1: 1.5～4 with the part by weight that extracts solvent, stirs, and filters, and taking liquid is subsequent use; The medicinal residues that obtain after filtering were flooded taking liquid 2 days and 1 day under the reuse extraction solvent room temperature respectively;
Step 3) merges three dipping medicinal liquids that above-mentioned steps obtains and concentrates, dry behind the extractum, promptly get.
In order to make those skilled in the art understand technical scheme of the present invention better, the present invention is done further detailed description below in conjunction with specific embodiment.
Embodiment 1: Chinese medicine composition prescription of the present invention and method for preparing
Prescription: Flos Lonicerae 10 grams, Fructus Forsythiae 10 grams, Herba Houttuyniae 10 grams, Rhizoma Polygoni Cuspidati 10 grams, Fructus Arctii, 10 grams; Semen Lepidii (Semen Descurainiae) 10 grams, Rhizoma Belamcandae 10 grams, Bulbus Fritillariae Thunbergii 10 grams, the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Fructus Perillae 10 grams; Windproof 10 grams, Rhizoma Coptidis 10 grams, Radix Scutellariae 12 grams, restrain Radix Ophiopogonis 10, Radix Adenophorae (Radix Glehniae) 15 grams, Radix Glycyrrhizae 5 grams.
Method for preparing:
1) takes by weighing each crude drug according to above-mentioned weight, mix, pulverize;
2) under the room temperature above-mentioned raw materials medicine was flooded in water 3 days, the part by weight of crude drug and water is 1: 1.5, stirs, and filters, and taking liquid is subsequent use; Medicinal residues reuse water retting twice with obtaining after filtering flooded taking liquid respectively 2 days and 1 day;
3) merge the dipping medicinal liquid three times, concentrate, get extractum, oven dry promptly gets.
Embodiment 2: Chinese medicine composition prescription of the present invention and method for preparing
Prescription: Flos Lonicerae 15 grams, Fructus Forsythiae 15 grams, Herba Houttuyniae 15 grams, Rhizoma Polygoni Cuspidati 15 grams, Fructus Arctii 12 grams, Semen Lepidii (Semen Descurainiae) 10 grams; Rhizoma Belamcandae 12 grams, Bulbus Fritillariae Thunbergii 12 grams, the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, restrain Radix Ophiopogonis 12, Radix Adenophorae (Radix Glehniae) 20 grams; Fructus Perillae 10 grams, windproof 12 grams, Rhizoma Coptidis 10 grams, Radix Scutellariae 12 grams, Radix Glycyrrhizae 5 grams.
Method for preparing:
1) takes by weighing each crude drug according to above-mentioned weight, mix, pulverize;
2) under the room temperature above-mentioned raw materials medicine was flooded 3 days in 60% ethanol, crude drug and 60% alcoholic acid part by weight are 1: 2, stir, and filter, and taking liquid is subsequent use; With medicinal residues reuse 60% alcohol dipping twice that obtains after filtering, flooded taking liquid respectively 2 days and 1 day;
3) merge the dipping medicinal liquid three times, concentrate, get extractum, oven dry promptly gets.
Embodiment 3: Chinese medicine composition prescription of the present invention and method for preparing
Prescription: Flos Lonicerae 20 grams, Fructus Forsythiae 20 grams, Herba Houttuyniae 20 grams, Rhizoma Polygoni Cuspidati 20 grams, Fructus Arctii 12 grams, Semen Lepidii (Semen Descurainiae) 10 grams; Rhizoma Belamcandae 12 grams, Bulbus Fritillariae Thunbergii 15 grams, the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, restrain Radix Ophiopogonis 15, Radix Adenophorae (Radix Glehniae) 20 grams; Fructus Perillae 10 grams, windproof 12 grams, Rhizoma Coptidis 10 grams, Radix Scutellariae 12 grams, Radix Glycyrrhizae 10 grams.
Method for preparing:
1) takes by weighing each crude drug according to above-mentioned weight, mix, pulverize;
2) under the room temperature above-mentioned raw materials medicine was flooded in water 3 days, the part by weight of crude drug and water is 1: 2.5, stirs, and filters, and taking liquid is subsequent use; Medicinal residues reuse water retting twice with obtaining after filtering flooded taking liquid respectively 2 days and 1 day;
3) merge the dipping medicinal liquid three times, concentrate, get extractum, oven dry promptly gets.
Embodiment 4: Chinese medicine composition prescription of the present invention and method for preparing
Prescription: Flos Lonicerae 25 grams, Fructus Forsythiae 25 grams, Herba Houttuyniae 25 grams, Rhizoma Polygoni Cuspidati 25 grams, Fructus Arctii 12 grams, Semen Lepidii (Semen Descurainiae) 10 grams; Rhizoma Belamcandae 12 grams, Bulbus Fritillariae Thunbergii 15 grams, the Radix Astragali 25 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, restrain Radix Ophiopogonis 20, Radix Adenophorae (Radix Glehniae) 25 grams; Fructus Perillae 10 grams, windproof 12 grams, Rhizoma Coptidis 12 grams, Radix Scutellariae 15 grams, Radix Glycyrrhizae 10 grams.
Method for preparing:
1) takes by weighing each crude drug according to above-mentioned weight, mix, pulverize;
2) under the room temperature above-mentioned raw materials medicine was flooded 3 days in 60% ethanol, crude drug and 60% alcoholic acid part by weight are 1: 3.5, stir, and filter, and taking liquid is subsequent use; With medicinal residues reuse 60% alcohol dipping twice that obtains after filtering, flooded taking liquid respectively 2 days and 1 day;
3) merge the dipping medicinal liquid three times, concentrate, get extractum, oven dry promptly gets.
Embodiment 5: Chinese medicine composition prescription of the present invention and method for preparing
Prescription: Flos Lonicerae 30 grams, Fructus Forsythiae 30 grams, Herba Houttuyniae 30 grams, Rhizoma Polygoni Cuspidati 30 grams, Fructus Arctii 15 grams, Semen Lepidii (Semen Descurainiae) 12 grams; Rhizoma Belamcandae 15 grams, Bulbus Fritillariae Thunbergii 20 grams, the Radix Astragali 30 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, restrain Radix Ophiopogonis 20, Radix Adenophorae (Radix Glehniae) 30 grams; Fructus Perillae 15 grams, windproof 15 grams, Rhizoma Coptidis 12 grams, Radix Scutellariae 15 grams, Radix Glycyrrhizae 10 grams.
Method for preparing:
1) takes by weighing each crude drug according to above-mentioned weight, mix, pulverize;
2) under the room temperature above-mentioned raw materials medicine was flooded 3 days in 60% ethanol, crude drug and 60% alcoholic acid part by weight are 1: 4, stir, and filter, and taking liquid is subsequent use; With medicinal residues reuse 60% alcohol dipping twice that obtains after filtering, flooded taking liquid respectively 2 days and 1 day;
3) merge the dipping medicinal liquid three times, concentrate, get extractum, oven dry promptly gets.
Embodiment 6: Chinese medicine composition of the present invention is to Pulmonary Fungal Infections patient's clinical trial
(1) medicine and administering mode, dosage
Experimental group: adopt the prepared Chinese medicine composition of embodiment 1-5.
The experimental group drug usage: 1.35g/ time, one day 2 times, 4 weeks of logotype.
Matched group: itraconazole capsule (Janssen Pharmaceutica company limited)
The matched group drug usage: 200mg-400mg/ time, oral one day 1-2 time, 4 weeks of logotype.
(2) group technology:
Select diagnose clear and definite Pulmonary Fungal Infections 246 examples in hospital year October in January, 2010 to 2011, male's 142 examples wherein, women's 104 examples in my institute (No.2 Hospital Attached to No.3 Military Medical College, PLA); Age is from 17～68 years old, 50.5 years old mean age; The course of disease was from 1 month～9 months.246 patients are divided into five groups at random; The Chinese medicine composition group and the matched group that promptly use embodiment 1-5 to process: embodiment 1 group of (first group), embodiment 2 groups of (second group), 4 groups of (the 4th group) embodiment of 3 groups of (the 3rd group) embodiment of embodiment 5 groups of (the 5th group) and matched groups, every group 41 people.
(3) therapeutic evaluation standard
1., clinical recovery: clinical symptoms complete obiteration, iconography change no abnormal, do not have recurrence after the drug withdrawal;
2., produce effects: most of clinical symptom disappearance such as cough, subjective symptoms significantly alleviates or disappears; Rabat: no abnormal.
3., take a turn for the better: most of clinical symptom disappearance such as cough are more than 2/3, and subjective symptoms alleviates;
4., invalid: treating forward and backward symptom and rabat does not have obvious improvement or aggravation.
(4) statistical method
Adopt the clinical efficacy of more above-mentioned each group of chi-square criterion, p＜0.05 expression has statistical significance.
(5) experimental result is seen table 1
The curative effect of table 1 various dose treatment Pulmonary Fungal Infections medicine
Compare * P＜0.05 with matched group
Research shows that the pharmaceutical capsules of the treatment Pulmonary Fungal Infections that the present invention relates to compares with conventional at present itraconazole capsule for treating, determined curative effect, and side effect is little, has certain superiority; And cheap, make simplely, have good promotion prospect.
The above only is a preferred implementation of the present invention; Should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention; Can also make some improvement and retouching, these improvement and retouching also should be regarded as protection scope of the present invention.
Claims (7)
1. Chinese medicine composition of treating Pulmonary Fungal Infections; It is characterized in that contained active component is prepared from following raw materials according by weight ratio: 8～32 parts of Flos Lonicerae, 8～32 parts of Fructus Forsythiaes, 8～32 parts of Herba Houttuyniae, 8～32 parts of Rhizoma Polygoni Cuspidati, 8～15 parts of Fructus Arctiis, 8～15 parts of Semen Lepidii (Semen Descurainiae)s, 8～15 parts of Rhizoma Belamcandae, 8～20 parts of Bulbus Fritillariae Thunbergiis, 8～15 parts of Fructus Perillaes, 20～32 parts of the Radixs Astragali, windproof 8～15 parts, 8～20 parts of the Rhizoma Atractylodis Macrocephalaes, 8～20 parts of Radix Ophiopogonis, 15～32 parts of Radix Adenophorae (Radix Glehniae), 8～15 parts of Rhizoma Coptidis, 10～15 parts of Radix Scutellariaes, 5～12 parts in Radix Glycyrrhizae.
2. Chinese medicine composition according to claim 1; It is characterized in that contained active component is prepared from following raw materials according by weight ratio: 10～30 parts of Flos Lonicerae, 10～30 parts of Fructus Forsythiaes, 10～30 parts of Herba Houttuyniae, 10～30 parts of Rhizoma Polygoni Cuspidati, 10～15 parts of Fructus Arctiis, 10～12 parts of Semen Lepidii (Semen Descurainiae)s, 10～15 parts of Rhizoma Belamcandae, 10～20 parts of Bulbus Fritillariae Thunbergiis, 10～15 parts of Fructus Perillaes, 20～30 parts of the Radixs Astragali, windproof 10～15 parts, 10～20 parts of the Rhizoma Atractylodis Macrocephalaes, 10～20 parts of Radix Ophiopogonis, 15～30 parts of Radix Adenophorae (Radix Glehniae), 10～12 parts of Rhizoma Coptidis, 12～15 parts of Radix Scutellariaes, 5～10 parts in Radix Glycyrrhizae.
3. Chinese medicine composition according to claim 1 and 2; It is characterized in that contained active component is prepared from following raw materials according by weight ratio: 30 parts of Flos Lonicerae, 30 parts of Fructus Forsythiaes, 30 parts of Herba Houttuyniae, 30 parts of Rhizoma Polygoni Cuspidati, 15 parts of Fructus Arctiis, 12 parts of Semen Lepidii (Semen Descurainiae)s, 15 parts of Rhizoma Belamcandae, 20 parts of Bulbus Fritillariae Thunbergiis, 15 parts of Fructus Perillaes, 30 parts of the Radixs Astragali, windproof 15 parts, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts of Radix Ophiopogonis, 30 parts of Radix Adenophorae (Radix Glehniae), 12 parts of Rhizoma Coptidis, 15 parts of Radix Scutellariaes, 10 parts in Radix Glycyrrhizae.
4. a method for preparing like any said Chinese medicine composition of claim 1～3 is characterized in that, may further comprise the steps:
Step 1) takes by weighing the medical material of respectively distinguishing the flavor of by said weight portion proportioning, and crude drug is mixed, pulverizes;
Step 2) under the room temperature above-mentioned raw materials medicine is flooded 3 times in extracting solvent, said crude drug is 1: 1.5～4 with the part by weight that extracts solvent, stirs, and filters, and taking liquid is subsequent use;
Step 3) merges three dipping medicinal liquids that above-mentioned steps obtains and concentrates, dry behind the extractum, promptly get.
5. method according to claim 4 is characterized in that step 2) said extraction solvent is 60% ethanol.
6. method according to claim 4 is characterized in that step 2) time of said dipping 3 times is 3 days, 2 days and 1 day respectively.
7. one kind like any said Chinese medicine composition of claim 1～3 dosage form clinically, it is characterized in that this dosage form is any one in oral solutions, tablet, powder, capsule, pill, the granule.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103550664A (en) * | 2013-10-31 | 2014-02-05 | 钱丹丹 | Traditional Chinese medicine for treating pneumonia |
| CN103989919A (en) * | 2014-04-21 | 2014-08-20 | 史家举 | Traditional Chinese medicine composition for relieving cough and resolving phlegm |
| KR101619733B1 (en) * | 2014-10-17 | 2016-05-12 | 원광대학교산학협력단 | A composition for anti-tussive activity or discharge of phlegm activity comprising of lonicera japonica, scutellaria baicalensis, adenophorea radix and polygonati odorati |
| CN105770219A (en) * | 2016-03-24 | 2016-07-20 | 钱浩 | Anti-infection spray formula |
| KR101732720B1 (en) * | 2014-10-17 | 2017-05-04 | 유한회사한풍제약 | A composition for anti-tussive activity or discharge of phlegm activity comprising of lonicera japonica, scutellaria baicalensis and liriopis tuber |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110600A (en) * | 1995-01-17 | 1995-10-25 | 河南省焦作市卫生材料厂 | Antalgic paster and its preparation method |
| CN1174732A (en) * | 1997-07-14 | 1998-03-04 | 迟经惠 | Powder medicine for pulmonary abscess |
| CN1194843A (en) * | 1997-04-01 | 1998-10-07 | 李恩洪 | Method for producing green health medicine |
| CN1352964A (en) * | 2000-11-06 | 2002-06-12 | 曾广财 | Powdered medicine for treating pulmonary tuberculosis |
| CN1562151A (en) * | 2004-03-30 | 2005-01-12 | 沈惠明 | Medicinal formulation for treating upper respiratory track infection and its design method |
| CN101199738A (en) * | 2006-12-16 | 2008-06-18 | 张元正 | Medicament for treating cough and gasp disease |
-
2012
- 2012-02-15 CN CN 201210033959 patent/CN102526467B/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110600A (en) * | 1995-01-17 | 1995-10-25 | 河南省焦作市卫生材料厂 | Antalgic paster and its preparation method |
| CN1194843A (en) * | 1997-04-01 | 1998-10-07 | 李恩洪 | Method for producing green health medicine |
| CN1174732A (en) * | 1997-07-14 | 1998-03-04 | 迟经惠 | Powder medicine for pulmonary abscess |
| CN1352964A (en) * | 2000-11-06 | 2002-06-12 | 曾广财 | Powdered medicine for treating pulmonary tuberculosis |
| CN1562151A (en) * | 2004-03-30 | 2005-01-12 | 沈惠明 | Medicinal formulation for treating upper respiratory track infection and its design method |
| CN101199738A (en) * | 2006-12-16 | 2008-06-18 | 张元正 | Medicament for treating cough and gasp disease |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103550664A (en) * | 2013-10-31 | 2014-02-05 | 钱丹丹 | Traditional Chinese medicine for treating pneumonia |
| CN103989919A (en) * | 2014-04-21 | 2014-08-20 | 史家举 | Traditional Chinese medicine composition for relieving cough and resolving phlegm |
| KR101619733B1 (en) * | 2014-10-17 | 2016-05-12 | 원광대학교산학협력단 | A composition for anti-tussive activity or discharge of phlegm activity comprising of lonicera japonica, scutellaria baicalensis, adenophorea radix and polygonati odorati |
| KR101732720B1 (en) * | 2014-10-17 | 2017-05-04 | 유한회사한풍제약 | A composition for anti-tussive activity or discharge of phlegm activity comprising of lonicera japonica, scutellaria baicalensis and liriopis tuber |
| CN105770219A (en) * | 2016-03-24 | 2016-07-20 | 钱浩 | Anti-infection spray formula |
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