CN102482324B - 能够抑制自身免疫、炎症和癌症进程的新型趋化因子结合多肽 - Google Patents

能够抑制自身免疫、炎症和癌症进程的新型趋化因子结合多肽 Download PDF

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CN102482324B
CN102482324B CN201080036127.9A CN201080036127A CN102482324B CN 102482324 B CN102482324 B CN 102482324B CN 201080036127 A CN201080036127 A CN 201080036127A CN 102482324 B CN102482324 B CN 102482324B
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bkt
polypeptide
seq
chemokine
peptide
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CN102482324A (zh
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米哈尔·亚伯拉罕
奥尔利·艾森贝格
阿蒙·佩勒德
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Biokine Therapeutics Ltd
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CN201080036127.9A 2009-06-15 2010-06-15 能够抑制自身免疫、炎症和癌症进程的新型趋化因子结合多肽 Expired - Fee Related CN102482324B (zh)

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Application Number Priority Date Filing Date Title
US21349309P 2009-06-15 2009-06-15
US61/213,493 2009-06-15
PCT/IL2010/000473 WO2010146584A1 (en) 2009-06-15 2010-06-15 Novel chemokine binding polypeptides capable of inhibiting the course of autoimmunity, inflammation and cancer

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CN102482324A CN102482324A (zh) 2012-05-30
CN102482324B true CN102482324B (zh) 2014-07-02

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US (3) US8685398B2 (enExample)
EP (1) EP2443137B1 (enExample)
JP (1) JP5784010B2 (enExample)
KR (1) KR20120046163A (enExample)
CN (1) CN102482324B (enExample)
BR (1) BRPI1009716A2 (enExample)
CA (1) CA2765188A1 (enExample)
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HU (1) HUE025294T2 (enExample)
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ES2403932T3 (es) 2002-08-27 2013-05-22 Biokine Therapeutics Ltd. Antagonista de CXCR4 y uso del mismo
US8455450B2 (en) 2006-12-21 2013-06-04 Biokine Therapeutics Ltd. Methods for obtaining a therapeutically effective amount of hematopoietic precursor cells and long term engraftment thereof
ES2462517T3 (es) 2009-06-14 2014-05-23 Biokine Therapeutics Ltd. Terapia con péptidos para aumentar los niveles de plaquetas
EP2443137B1 (en) 2009-06-15 2015-05-20 Biokine Therapeutics Ltd. Novel chemokine binding polypeptides capable of inhibiting the course of autoimmunity, inflammation and cancer
WO2012095849A1 (en) 2011-01-10 2012-07-19 Biokine Therapeutics Ltd. Peptides and compositions for the treatment of neuroectodermal derived tumors and retinoblastoma
WO2013160895A1 (en) 2012-04-24 2013-10-31 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
CN106188237A (zh) * 2014-09-05 2016-12-07 马恒标 大蒜中提取得到的抗肿瘤活性的多肽
US20170226157A1 (en) * 2014-12-09 2017-08-10 Biokine Therapeutics Ltd. Compositions and methods for the treatment of ocular diseases
CN107921087A (zh) 2015-07-16 2018-04-17 百欧肯治疗有限公司 治疗癌症的组合物及方法
WO2017103931A1 (en) 2015-12-17 2017-06-22 Biokine Therapeutics Ltd. Small molecules against cancer
KR102828755B1 (ko) 2015-12-17 2025-07-03 바이오카인 테라퓨틱스 리미티드 케모카인 활성 및/또는 암세포 성장 억제용 저분자
US20170204154A1 (en) 2016-01-20 2017-07-20 Delinia, Inc. Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
BR112018016924A2 (pt) 2016-02-23 2019-01-02 Biolinerx Ltd método de seleção de regime de tratamento para indivíduo que tem leucemia mieloide aguda (lma), método de maximização de resposta ao tratamento de leucemia mieloide aguda (lma), método de tratamento de lma, antagonista de cxcr4 e agente quimioterápico no tratamento de lma
WO2020030672A1 (en) * 2018-08-10 2020-02-13 Pantherna Therapeutics Gmbh Recombinant nucleic acid construct
KR20200044321A (ko) * 2018-10-19 2020-04-29 아이진 주식회사 염증성 질환의 예방 또는 치료용 약학적 조성물
CA3090315C (en) 2019-05-15 2023-09-19 Biokine Therapeutics Ltd. 8-phenoxy-quinolinone derivatives for treating cancer, inhibiting chemokine activity and/or inducing cell death
KR102736939B1 (ko) * 2021-09-30 2024-12-03 (주)케어젠 항염증 활성을 갖는 펩타이드 및 이의 용도
KR102609822B1 (ko) * 2021-10-05 2023-12-06 (주)케어젠 항염증 활성을 갖는 펩타이드와 이의 용도

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WO2003072599A2 (en) * 2002-02-28 2003-09-04 Biokine Therapeutics Ltd. Novel chemokine binding peptides capable of modulating the biological activity of chemokines
WO2007052173A2 (en) * 2005-02-23 2007-05-10 Endocube S.A.S. Activity of thap-family chemokine-binding domains
WO2007094005A2 (en) * 2006-02-17 2007-08-23 Rappaport Family Institute For Research In The Medical Sciences Molecules and methods of using same for treating ccr5/ccr5 ligands associated diseases

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CA2765188A1 (en) 2010-12-23
CN102482324A (zh) 2012-05-30
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HUE025294T2 (en) 2016-02-29
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BRPI1009716A2 (pt) 2016-10-11
US20120087921A1 (en) 2012-04-12
JP5784010B2 (ja) 2015-09-24
WO2010146584A1 (en) 2010-12-23
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