CN102482324B - 能够抑制自身免疫、炎症和癌症进程的新型趋化因子结合多肽 - Google Patents

能够抑制自身免疫、炎症和癌症进程的新型趋化因子结合多肽 Download PDF

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CN102482324B
CN102482324B CN201080036127.9A CN201080036127A CN102482324B CN 102482324 B CN102482324 B CN 102482324B CN 201080036127 A CN201080036127 A CN 201080036127A CN 102482324 B CN102482324 B CN 102482324B
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bkt
polypeptide
seq
chemokine
peptide
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CN102482324A (zh
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米哈尔·亚伯拉罕
奥尔利·艾森贝格
阿蒙·佩勒德
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Biokine Therapeutics Ltd
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CN201080036127.9A 2009-06-15 2010-06-15 能够抑制自身免疫、炎症和癌症进程的新型趋化因子结合多肽 Expired - Fee Related CN102482324B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21349309P 2009-06-15 2009-06-15
US61/213,493 2009-06-15
PCT/IL2010/000473 WO2010146584A1 (en) 2009-06-15 2010-06-15 Novel chemokine binding polypeptides capable of inhibiting the course of autoimmunity, inflammation and cancer

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Publication Number Publication Date
CN102482324A CN102482324A (zh) 2012-05-30
CN102482324B true CN102482324B (zh) 2014-07-02

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US (3) US8685398B2 (enExample)
EP (1) EP2443137B1 (enExample)
JP (1) JP5784010B2 (enExample)
KR (1) KR20120046163A (enExample)
CN (1) CN102482324B (enExample)
BR (1) BRPI1009716A2 (enExample)
CA (1) CA2765188A1 (enExample)
DK (1) DK2443137T3 (enExample)
HU (1) HUE025294T2 (enExample)
MX (1) MX2011013457A (enExample)
WO (1) WO2010146584A1 (enExample)

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US7423007B2 (en) 2002-08-27 2008-09-09 Biokine Therapeutics Ltd. Cxcr4 antagonist and use thereof
CA2673484A1 (en) 2006-12-21 2008-06-26 Biokine Therapeutics Ltd. T-140 peptide analogs having cxcr4 super-agonist activity for cancer therapy
WO2010146578A2 (en) 2009-06-14 2010-12-23 Biokine Therapeutics Ltd. Peptide therapy for increasing platelet levels
BRPI1009716A2 (pt) 2009-06-15 2016-10-11 Biokine Therapeutics Ltd ligações péptidicas de quemoquina, capazes de inibir o curso da autoimunidade, inflamação e câncer
EP2663320A1 (en) 2011-01-10 2013-11-20 Biokine Therapeutics Ltd. Peptides and compositions for the treatment of neuroectodermal derived tumors and retinoblastoma
US9439942B2 (en) 2012-04-24 2016-09-13 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
CN106317202A (zh) * 2014-09-05 2017-01-11 马恒标 大蒜中提取得到的抗肿瘤活性的多肽
WO2016092544A1 (en) * 2014-12-09 2016-06-16 Biokine Therapeutics Ltd. Compositions and methods for the treatment of ocular diseases
CA2986705A1 (en) 2015-07-16 2017-01-19 Biokine Therapeutics Ltd. A cxcr4 inhibitor and a pdi antagonist for use in treating cancer
US10646465B2 (en) 2015-12-17 2020-05-12 Biokine Therapeutics Ltd. Small molecules against cancer
JP6941611B2 (ja) 2015-12-17 2021-09-29 バイオカイン セラピューティックス リミテッド ケモカイン活性および／または癌細胞成長を阻害するための小分子
US20170204154A1 (en) 2016-01-20 2017-07-20 Delinia, Inc. Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
EP3419645B1 (en) 2016-02-23 2020-09-02 BioLineRx Ltd. Method of selecting a treatment regimen in acute myeloid leukemia (aml)
HUE066311T2 (hu) * 2018-08-10 2024-07-28 Pantherna Therapeutics Gmbh Rekombináns nukleinsav-konstrukció
KR20200044321A (ko) * 2018-10-19 2020-04-29 아이진 주식회사 염증성 질환의 예방 또는 치료용 약학적 조성물
EP4524131A1 (en) 2019-05-15 2025-03-19 AlonBio Ltd. Small molecules for treating cancer, inhabiting chemokine activity and/or inducing cell death
KR102736939B1 (ko) * 2021-09-30 2024-12-03 (주)케어젠 항염증 활성을 갖는 펩타이드 및 이의 용도
KR102609822B1 (ko) * 2021-10-05 2023-12-06 (주)케어젠 항염증 활성을 갖는 펩타이드와 이의 용도

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WO2003072599A2 (en) * 2002-02-28 2003-09-04 Biokine Therapeutics Ltd. Novel chemokine binding peptides capable of modulating the biological activity of chemokines
WO2007052173A2 (en) * 2005-02-23 2007-05-10 Endocube S.A.S. Activity of thap-family chemokine-binding domains
WO2007094005A2 (en) * 2006-02-17 2007-08-23 Rappaport Family Institute For Research In The Medical Sciences Molecules and methods of using same for treating ccr5/ccr5 ligands associated diseases

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CN102482324A (zh) 2012-05-30
US9493557B2 (en) 2016-11-15
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KR20120046163A (ko) 2012-05-09
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