CN102448493B - 胰岛素抗性疾病的治疗 - Google Patents

胰岛素抗性疾病的治疗 Download PDF

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Publication number
CN102448493B
CN102448493B CN201080023924.3A CN201080023924A CN102448493B CN 102448493 B CN102448493 B CN 102448493B CN 201080023924 A CN201080023924 A CN 201080023924A CN 102448493 B CN102448493 B CN 102448493B
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antibody
antibodies
insulin
human
insulin resistance
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Chinese (zh)
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CN102448493A (zh
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G·A·科卢玛姆
Y·(H)·胡
W·欧阳
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201080023924.3A 2009-04-01 2010-03-30 胰岛素抗性疾病的治疗 Active CN102448493B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16567709P 2009-04-01 2009-04-01
US61/165,677 2009-04-01
PCT/US2010/029280 WO2010114859A1 (en) 2009-04-01 2010-03-30 Treatment of insulin-resistant disorders

Publications (2)

Publication Number Publication Date
CN102448493A CN102448493A (zh) 2012-05-09
CN102448493B true CN102448493B (zh) 2014-04-30

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ID=42229822

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CN201080023924.3A Active CN102448493B (zh) 2009-04-01 2010-03-30 胰岛素抗性疾病的治疗

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US (1) US20100266595A1 (enExample)
EP (1) EP2413967A1 (enExample)
JP (1) JP5795306B2 (enExample)
KR (1) KR101766927B1 (enExample)
CN (1) CN102448493B (enExample)
AR (1) AR075998A1 (enExample)
AU (1) AU2010232692C1 (enExample)
BR (1) BRPI1011535A2 (enExample)
CA (1) CA2752908A1 (enExample)
CL (1) CL2011002416A1 (enExample)
CO (1) CO6410313A2 (enExample)
CR (1) CR20110552A (enExample)
EC (1) ECSP11011429A (enExample)
IL (1) IL214745A0 (enExample)
MA (1) MA33248B1 (enExample)
MX (1) MX347978B (enExample)
NZ (1) NZ595005A (enExample)
PE (1) PE20120628A1 (enExample)
RU (1) RU2537142C2 (enExample)
SG (1) SG174891A1 (enExample)
TW (1) TWI474833B (enExample)
UA (1) UA105384C2 (enExample)
WO (1) WO2010114859A1 (enExample)
ZA (1) ZA201106076B (enExample)

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SG10201608871XA (en) 2008-05-05 2016-12-29 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
US8790642B2 (en) 2008-08-29 2014-07-29 Genentech, Inc. Cross-reactive and bispecific anti-IL-17A/F antibodies
WO2012061129A1 (en) 2010-10-25 2012-05-10 Genentech, Inc Treatment of gastrointestinal inflammation and psoriasis a
US9117641B2 (en) 2012-10-29 2015-08-25 Perkinelmer Health Sciences, Inc. Direct sample analysis device adapters and methods of using them
ES2804719T3 (es) * 2013-02-04 2021-02-09 Sanofi Sa Formulaciones farmacéuticas estabilizadas de análogos de insulina y/o derivados de insulina
TWI641381B (zh) * 2013-02-04 2018-11-21 法商賽諾菲公司 胰島素類似物及／或胰島素衍生物之穩定化醫藥調配物
EP3091995B1 (en) 2014-01-09 2024-03-20 Sanofi Stabilized pharmaceutical formulations of insulin aspart
AR103173A1 (es) 2014-12-22 2017-04-19 Novarits Ag Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17
EP3592771A4 (en) 2017-03-10 2020-09-09 Suzhou Kanova Biopharmaceutical Co., Ltd. MONOCLONAL ANTIBODIES DIRECTED AGAINST IL-17A AND IL-17F AND ASSOCIATED USE

Citations (1)

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Also Published As

Publication number Publication date
RU2011144122A (ru) 2013-05-10
CO6410313A2 (es) 2012-03-30
KR20120005483A (ko) 2012-01-16
US20100266595A1 (en) 2010-10-21
TWI474833B (zh) 2015-03-01
EP2413967A1 (en) 2012-02-08
BRPI1011535A2 (pt) 2016-03-29
CR20110552A (es) 2011-12-07
WO2010114859A1 (en) 2010-10-07
MX2011010273A (es) 2011-10-17
AU2010232692B2 (en) 2016-12-01
AR075998A1 (es) 2011-05-11
CL2011002416A1 (es) 2012-04-20
ZA201106076B (en) 2012-11-28
CA2752908A1 (en) 2010-10-07
TW201038284A (en) 2010-11-01
AU2010232692C1 (en) 2017-06-01
UA105384C2 (ru) 2014-05-12
SG174891A1 (en) 2011-11-28
JP5795306B2 (ja) 2015-10-14
KR101766927B1 (ko) 2017-08-09
MA33248B1 (fr) 2012-05-02
CN102448493A (zh) 2012-05-09
JP2012522788A (ja) 2012-09-27
AU2010232692A1 (en) 2011-09-08
MX347978B (es) 2017-05-22
PE20120628A1 (es) 2012-05-26
RU2537142C2 (ru) 2014-12-27
NZ595005A (en) 2014-04-30
IL214745A0 (en) 2011-11-30
ECSP11011429A (es) 2011-12-30

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