CN102427815A - 使用氟喹诺酮类治疗肺部细菌感染的方法 - Google Patents
使用氟喹诺酮类治疗肺部细菌感染的方法 Download PDFInfo
- Publication number
- CN102427815A CN102427815A CN2010800180220A CN201080018022A CN102427815A CN 102427815 A CN102427815 A CN 102427815A CN 2010800180220 A CN2010800180220 A CN 2010800180220A CN 201080018022 A CN201080018022 A CN 201080018022A CN 102427815 A CN102427815 A CN 102427815A
- Authority
- CN
- China
- Prior art keywords
- antibacterial
- described method
- bacterial
- pulmonary bacterial
- fluoroquinolone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Abstract
Description
Claims (25)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610900988.6A CN107050032A (zh) | 2009-04-24 | 2010-04-22 | 使用氟喹诺酮类治疗肺部细菌感染的方法 |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17262509P | 2009-04-24 | 2009-04-24 | |
US61/172,625 | 2009-04-24 | ||
PCT/US2010/032128 WO2010124141A1 (en) | 2009-04-24 | 2010-04-22 | Methods of treating a pulmonary bacterial infection using fluoro-quinolones |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610900988.6A Division CN107050032A (zh) | 2009-04-24 | 2010-04-22 | 使用氟喹诺酮类治疗肺部细菌感染的方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN102427815A true CN102427815A (zh) | 2012-04-25 |
Family
ID=43011488
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2010800180220A Pending CN102427815A (zh) | 2009-04-24 | 2010-04-22 | 使用氟喹诺酮类治疗肺部细菌感染的方法 |
CN201610900988.6A Pending CN107050032A (zh) | 2009-04-24 | 2010-04-22 | 使用氟喹诺酮类治疗肺部细菌感染的方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610900988.6A Pending CN107050032A (zh) | 2009-04-24 | 2010-04-22 | 使用氟喹诺酮类治疗肺部细菌感染的方法 |
Country Status (27)
Country | Link |
---|---|
US (2) | US20120035166A1 (zh) |
EP (1) | EP2421539B1 (zh) |
JP (2) | JP6179844B2 (zh) |
KR (1) | KR20120034626A (zh) |
CN (2) | CN102427815A (zh) |
AU (1) | AU2010238765B2 (zh) |
BR (1) | BRPI1006626B8 (zh) |
CA (1) | CA2759874C (zh) |
CL (1) | CL2011002649A1 (zh) |
CO (1) | CO6450642A2 (zh) |
CY (1) | CY1122525T1 (zh) |
DK (1) | DK2421539T3 (zh) |
ES (1) | ES2755754T3 (zh) |
HR (1) | HRP20191951T1 (zh) |
HU (1) | HUE046595T2 (zh) |
IL (1) | IL215777A (zh) |
LT (1) | LT2421539T (zh) |
MX (1) | MX339077B (zh) |
MY (1) | MY178871A (zh) |
NZ (1) | NZ596245A (zh) |
PL (1) | PL2421539T3 (zh) |
PT (1) | PT2421539T (zh) |
RU (1) | RU2535056C2 (zh) |
SG (3) | SG175288A1 (zh) |
SI (1) | SI2421539T1 (zh) |
WO (1) | WO2010124141A1 (zh) |
ZA (1) | ZA201107903B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108849939A (zh) * | 2018-07-31 | 2018-11-23 | 广东省农业科学院植物保护研究所 | 盐酸左氧氟沙星在制备用于防治烟草青枯病的农药制剂中的应用 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8524735B2 (en) | 2005-05-18 | 2013-09-03 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
KR20160150110A (ko) | 2008-10-07 | 2016-12-28 | 랩터 파마슈티컬스 인코포레이티드 | 약동학 개선을 위한 에어로졸 플루오로퀴놀론 제형 |
PL2346509T3 (pl) | 2008-10-07 | 2021-03-08 | Horizon Orphan Llc | Lewofloksacyna w postaci aerozolu dla zmniejszania stanu zapalnego płuc |
CA2773033C (en) | 2009-09-04 | 2016-10-11 | Mpex Pharmaceuticals, Inc. | Use of aerosolized levofloxacin for treating cystic fibrosis |
US9572774B2 (en) | 2011-05-19 | 2017-02-21 | Savara Inc. | Dry powder vancomycin compositions and associated methods |
WO2014152326A1 (en) * | 2013-03-14 | 2014-09-25 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
JP6966835B2 (ja) * | 2016-02-05 | 2021-11-17 | ホライズン オーファン リミテッド ライアビリティ カンパニー | 嚢胞性線維症のためのフルオロキノロン製剤 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040009126A1 (en) * | 2002-03-05 | 2004-01-15 | Transave, Inc. | Inhalation system for prevention and treatment of intracellular infections |
CN101222927A (zh) * | 2005-05-18 | 2008-07-16 | Mpex医药有限公司 | 气溶胶化的氟喹诺酮类药物及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2255757C1 (ru) * | 2004-06-22 | 2005-07-10 | Санкт-Петербургская Общественная Организация "Санкт-Петербургский Институт Биорегуляции И Геронтологии Сзо Рамн" | Пептидное соединение, восстанавливающее функцию органов дыхания |
US7838532B2 (en) | 2005-05-18 | 2010-11-23 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
BRPI0913021A2 (pt) * | 2008-05-15 | 2015-10-13 | Novartis Ag | distribuição pulmonar de uma fluoroquinolona |
KR20160150110A (ko) * | 2008-10-07 | 2016-12-28 | 랩터 파마슈티컬스 인코포레이티드 | 약동학 개선을 위한 에어로졸 플루오로퀴놀론 제형 |
-
2010
- 2010-04-22 SG SG2011076932A patent/SG175288A1/en unknown
- 2010-04-22 WO PCT/US2010/032128 patent/WO2010124141A1/en active Application Filing
- 2010-04-22 BR BRPI1006626A patent/BRPI1006626B8/pt active IP Right Grant
- 2010-04-22 PT PT107678005T patent/PT2421539T/pt unknown
- 2010-04-22 CA CA2759874A patent/CA2759874C/en active Active
- 2010-04-22 HU HUE10767800A patent/HUE046595T2/hu unknown
- 2010-04-22 CN CN2010800180220A patent/CN102427815A/zh active Pending
- 2010-04-22 EP EP10767800.5A patent/EP2421539B1/en active Active
- 2010-04-22 SI SI201031951T patent/SI2421539T1/sl unknown
- 2010-04-22 KR KR1020117027809A patent/KR20120034626A/ko active Search and Examination
- 2010-04-22 SG SG10201811494SA patent/SG10201811494SA/en unknown
- 2010-04-22 PL PL10767800T patent/PL2421539T3/pl unknown
- 2010-04-22 NZ NZ596245A patent/NZ596245A/xx unknown
- 2010-04-22 JP JP2012507400A patent/JP6179844B2/ja active Active
- 2010-04-22 LT LT10767800T patent/LT2421539T/lt unknown
- 2010-04-22 CN CN201610900988.6A patent/CN107050032A/zh active Pending
- 2010-04-22 MX MX2011011190A patent/MX339077B/es active IP Right Grant
- 2010-04-22 ES ES10767800T patent/ES2755754T3/es active Active
- 2010-04-22 DK DK10767800T patent/DK2421539T3/da active
- 2010-04-22 MY MYPI2011005063A patent/MY178871A/en unknown
- 2010-04-22 RU RU2011145430/15A patent/RU2535056C2/ru active
- 2010-04-22 SG SG10201403512TA patent/SG10201403512TA/en unknown
- 2010-04-22 AU AU2010238765A patent/AU2010238765B2/en active Active
-
2011
- 2011-10-21 US US13/278,706 patent/US20120035166A1/en not_active Abandoned
- 2011-10-23 IL IL215777A patent/IL215777A/en active IP Right Grant
- 2011-10-24 CL CL2011002649A patent/CL2011002649A1/es unknown
- 2011-10-29 ZA ZA2011/07903A patent/ZA201107903B/en unknown
- 2011-11-02 CO CO11148624A patent/CO6450642A2/es not_active Application Discontinuation
-
2015
- 2015-10-09 JP JP2015201285A patent/JP6228580B2/ja not_active Expired - Fee Related
-
2019
- 2019-10-28 HR HRP20191951TT patent/HRP20191951T1/hr unknown
- 2019-11-06 CY CY20191101155T patent/CY1122525T1/el unknown
-
2020
- 2020-02-20 US US16/796,525 patent/US20210015811A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040009126A1 (en) * | 2002-03-05 | 2004-01-15 | Transave, Inc. | Inhalation system for prevention and treatment of intracellular infections |
CN101222927A (zh) * | 2005-05-18 | 2008-07-16 | Mpex医药有限公司 | 气溶胶化的氟喹诺酮类药物及其应用 |
Non-Patent Citations (1)
Title |
---|
KELLI L. PALMER,ET AL: "Membrane-Bound Nitrate Reductase Is Required for Anaerobic Growth in Cystic Fibrosis Sputum", 《JOURNAL OF BACTERIOLOGY》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108849939A (zh) * | 2018-07-31 | 2018-11-23 | 广东省农业科学院植物保护研究所 | 盐酸左氧氟沙星在制备用于防治烟草青枯病的农药制剂中的应用 |
CN108849939B (zh) * | 2018-07-31 | 2021-02-19 | 广东省农业科学院植物保护研究所 | 盐酸左氧氟沙星在制备用于防治烟草青枯病的农药制剂中的应用 |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20210015811A1 (en) | Methods of treating a pulmonary bacterial infection using fluoroquinolones | |
US20180055895A1 (en) | Bacteriophage-containing therapeutic agents | |
CN115869306A (zh) | Iowh-032用于制备抗革兰氏阳性细菌感染药物中的应用 | |
Mimoz et al. | Cefepime and amikacin synergy in vitro and in vivo against a ceftazidime-resistant strain of Enterobacter cloacae. | |
Smit et al. | Nocardia farcinica as the causative agent in a primary psoas abscess in a previously healthy cattle inspector | |
Dolan et al. | Two new nontoxic, non-pathogenic strains of Sphingomonas elodea for gellan gum production | |
Akinola et al. | Antibiotic sensitivity and sodium chloride susceptibility patterns of Flavobacterium columnare isolated from clinical columnaris in cultured Clarias gariepinus | |
CN117017983B (zh) | 曲普坦类药物在制备抗感染药物中的应用 | |
Davis et al. | Enrofloxacin use in a long-distance transport model of equine respiratory disease | |
Ahmed et al. | In vivo and In vitro Model for Evaluation of Anti-microbial activity: A Review | |
Dassanayake et al. | Administration of a bolus formulation of baquiloprim and sulphadimidine to calves: plasma concentration-time profiles and efficacy in suppressing experimental pneumonic pasteurellosis | |
El-Shennawy et al. | Antibacterial potentials of silver nanoparticles on multi-drug resistant Pseudomonas aeruginosa isolated from patients with catheter associated urinary tract infections | |
DE STAPHYLOCOCCUS et al. | STUDY ON THE ANTIBIOTIC RESISTANCE OF STRAINS OF STAPHYLOCOCCUS AUREUS ISOLATED FROM ANIMALS WITH CONTAGIOUS ECTHYMA | |
CN117085012A (zh) | 抗金黄色葡萄球菌药物增效剂及抗金黄色葡萄球菌药物 | |
CN115501324A (zh) | 一种复合抗菌剂及其应用 | |
Ray et al. | Alcaligenes Faecalis, An Opportunistic Pathogen of Multidrug Resistance | |
Kudaravalli et al. | ANTIBIOTIC SUSCEPTIBILITY PATTERNS OF BACTERIAL PATHOGENS TO AMINOGLYCOSIDES | |
TW201705949A (zh) | 抑制具抗藥性微生物之醫藥組合物及其方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20160503 Address after: California, USA Applicant after: Horizon Orphan LLC Address before: California, USA Applicant before: Pixar pharmaceuticals Ltd. Effective date of registration: 20160503 Address after: California, USA Applicant after: Pixar pharmaceuticals Ltd. Address before: California, USA Applicant before: MPEX PHARMACEUTICALS, Inc. |
|
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20120425 |
|
RJ01 | Rejection of invention patent application after publication |