CN102339356B - 应用代谢组学技术评价与预测药物毒性和药效的方法 - Google Patents
应用代谢组学技术评价与预测药物毒性和药效的方法 Download PDFInfo
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CN102788849B (zh) * | 2012-06-01 | 2013-11-13 | 中国人民解放军第二军医大学 | 一种色谱-质谱代谢组学数据分析的新方法 |
CN104655800A (zh) * | 2014-12-30 | 2015-05-27 | 中国农业科学院柑桔研究所 | 模拟室外的柑桔蚜虫生物活性测定和药效测定方法及其应用 |
CN105004825A (zh) * | 2015-05-05 | 2015-10-28 | 南京工业大学 | 一种基于成骨细胞细胞组织gc/ms代谢组学分析方法 |
CN105760708B (zh) * | 2016-01-25 | 2018-12-14 | 哈尔滨工业大学深圳研究生院 | 一种代谢混合物ms/ms质谱的仿真生成方法及系统 |
CN107167617B (zh) * | 2017-05-26 | 2018-09-25 | 山东师范大学 | 鉴定ic50剂量维生素c对raw264.7和k562细胞差异标志物的方法 |
CN110044997B (zh) * | 2018-01-15 | 2023-08-04 | 中国医学科学院药物研究所 | 一种体内药物的离子强度虚拟校正和定量质谱成像分析方法 |
CN110646601A (zh) * | 2019-10-15 | 2020-01-03 | 大连工业大学 | 一种重金属暴露对细胞脂质代谢影响的检测方法 |
CN113009537B (zh) * | 2021-02-18 | 2023-10-31 | 中国人民解放军国防科技大学 | 一种惯导辅助卫导相对定位单历元部分模糊度求解方法 |
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CN101813680A (zh) * | 2010-04-08 | 2010-08-25 | 中国药科大学 | 一种应用代谢组学技术定量评价药物毒性的方法 |
CN102100706A (zh) * | 2009-12-18 | 2011-06-22 | 中国科学院大连化学物理研究所 | 一种应用代谢组学对中成药质量评价的方法 |
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US20050170441A1 (en) * | 2003-09-12 | 2005-08-04 | Health Research, Inc. | Early detection of cancer of specific type using 1HNMR metabonomics |
EP1886134B1 (en) * | 2005-06-03 | 2017-01-18 | Waters Technologies Corporation | Methods for fractionation-based chemical analyses |
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CN102100706A (zh) * | 2009-12-18 | 2011-06-22 | 中国科学院大连化学物理研究所 | 一种应用代谢组学对中成药质量评价的方法 |
CN101813680A (zh) * | 2010-04-08 | 2010-08-25 | 中国药科大学 | 一种应用代谢组学技术定量评价药物毒性的方法 |
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