CN102272287B - 冷冻干燥粉末状菌体及其制造方法 - Google Patents

冷冻干燥粉末状菌体及其制造方法 Download PDF

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Publication number
CN102272287B
CN102272287B CN201080004172.6A CN201080004172A CN102272287B CN 102272287 B CN102272287 B CN 102272287B CN 201080004172 A CN201080004172 A CN 201080004172A CN 102272287 B CN102272287 B CN 102272287B
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lyophilize
thalline
powdered
trehalose
manufacture method
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CN102272287A (zh
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上条政幸
寺原正树
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Meiji Co Ltd
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Meiji Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CN201080004172.6A 2009-03-04 2010-03-03 冷冻干燥粉末状菌体及其制造方法 Active CN102272287B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009051118 2009-03-04
JP2009-051118 2009-03-04
PCT/JP2010/053421 WO2010101175A1 (fr) 2009-03-04 2010-03-03 Poudre lyophilisée de cellules microbiennes et son procédé de fabrication

Publications (2)

Publication Number Publication Date
CN102272287A CN102272287A (zh) 2011-12-07
CN102272287B true CN102272287B (zh) 2014-12-10

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ID=42709730

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CN201080004172.6A Active CN102272287B (zh) 2009-03-04 2010-03-03 冷冻干燥粉末状菌体及其制造方法

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JP (1) JP5583114B2 (fr)
CN (1) CN102272287B (fr)
HK (1) HK1159688A1 (fr)
SG (1) SG172859A1 (fr)
TW (1) TWI501731B (fr)
WO (1) WO2010101175A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110189343A1 (en) * 2008-06-26 2011-08-04 Hideo Hasegawa Nano-sized lactic acid bacteria
JP2012055288A (ja) * 2010-09-13 2012-03-22 Kaneka Corp 安定化された生菌製剤およびその製造方法。
JP6032737B2 (ja) * 2012-09-27 2016-11-30 株式会社明治 ビフィズス菌の検出方法
JP6230796B2 (ja) * 2013-03-08 2017-11-15 日清食品ホールディングス株式会社 凍結乾燥菌試料およびその製造方法
TW201636010A (zh) * 2014-12-26 2016-10-16 Meiji Co Ltd 有機酸的產生促進劑、發炎性腸疾病的預防及／或改善劑
JP6807677B2 (ja) * 2016-07-15 2021-01-06 株式会社明治 微生物培養液の濃縮方法及び微生物濃縮物
CN110177866B (zh) * 2016-07-15 2023-06-20 Cj第一制糖株式会社 气体产生量低的肠膜明串珠菌cjlm627菌株以及使用该菌株制作泡菜的方法
RU2731642C2 (ru) * 2016-07-15 2020-09-07 СиДжей ЧЕИЛДЗЕДАНГ КОРПОРЕЙШН Штамм cjlm119 leuconostoc mesenteroides, продуцирующий пониженное количество газа, и способ приготовления кимчи с использованием этого штамма
HUE065092T2 (hu) 2016-07-15 2024-04-28 Cj Cheiljedang Corp Csökkent mennyiségû gázt termelõ Leuconostoc mesenteroides CJLM181 törzs és kimcsi elõállítási eljárása ennek alkalmazásával
CN111534434B (zh) * 2020-06-28 2022-07-05 江南大学 一种冻干保护剂及其在冻干青春双歧杆菌中的应用
CN113005040B (zh) * 2021-01-22 2023-07-25 武汉微康益生菌研究院有限公司 一种乳双歧杆菌冻干保护剂及其使用方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006273852A (ja) * 2005-03-03 2006-10-12 Meiji Milk Prod Co Ltd ビフィズス菌を有効成分とするアレルギー予防および／または治療剤
CN1922305A (zh) * 2004-02-24 2007-02-28 科·汉森有限公司 单个颗粒的冷冻乳酸菌培养物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0638704A (ja) * 1991-06-19 1994-02-15 Morinaga Milk Ind Co Ltd 発酵調味料及びその製造法
JPH0551321A (ja) * 1991-08-23 1993-03-02 Yotsuba Nyugyo Kk 免疫賦活剤
JPH08187071A (ja) * 1995-01-11 1996-07-23 Morinaga Milk Ind Co Ltd 食品の保存方法
EP1493806A1 (fr) * 2003-07-02 2005-01-05 Chr. Hansen A/S Utilisation de compositions impliquées dans la biosynthèse d'acides nucléiques comme agents cryoprotecteurs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1922305A (zh) * 2004-02-24 2007-02-28 科·汉森有限公司 单个颗粒的冷冻乳酸菌培养物
JP2006273852A (ja) * 2005-03-03 2006-10-12 Meiji Milk Prod Co Ltd ビフィズス菌を有効成分とするアレルギー予防および／または治療剤

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
B. De Giulio et al..Use of alginate and cryo-protective sugars to improve the viability of lactic acid bacteria after freezing and freeze-drying.《World Journal of Microbiology & Biotechnology》.2005,第21卷全文. *
B. De Giulio et al..Use of alginate and cryo-protective sugars to improve the viability of lactic acid bacteria after freezing and freeze-drying.《World Journal of Microbiology &amp *
Biotechnology》.2005,第21卷全文. *
Gaber Zayed & Yrjo H. Roos.Influence of trehalose and moisture content on survival of Lactobacillus salivarius subjected to freeze-drying and storage.《Process Biochemistry》.2004,第39卷(第9期),摘要部分，第1082页左栏倒数第6行至右栏第44行以及图1和图2. *
Gaber Zayed &amp *
Influence of fermentation time, cryoprotectant and neutralization of cell concentrate on freeze-drying survival, storage stability, and acid and bile exposure of Bifidobacterium animalis ssp. lactis cells produced without milk-based ingredients;M. Saarela et al.;《Journal of Applied Microbiology》;20051231;全文 *
M. Saarela et al..Influence of fermentation time, cryoprotectant and neutralization of cell concentrate on freeze-drying survival, storage stability, and acid and bile exposure of Bifidobacterium animalis ssp. lactis cells produced without milk-based ingredients.《Journal of Applied Microbiology》.2005,全文. *
SAMUEL B. LESLIE et al..Trehalose and Sucrose Protect Both Membranes and Proteins in Intact Bacteria during Drying.《APPLIED AND ENVIRONMENTAL MICROBIOLOGY》.1995,第61卷(第10期),全文. *
Trehalose and Sucrose Protect Both Membranes and Proteins in Intact Bacteria during Drying;SAMUEL B. LESLIE et al.;《APPLIED AND ENVIRONMENTAL MICROBIOLOGY》;19951030;第61卷(第10期);全文 *
Yrjo H. Roos.Influence of trehalose and moisture content on survival of Lactobacillus salivarius subjected to freeze-drying and storage.《Process Biochemistry》.2004,第39卷(第9期),摘要部分,第1082页左栏倒数第6行至右栏第44行以及图1和图2. *

Also Published As

Publication number Publication date
WO2010101175A1 (fr) 2010-09-10
TW201043152A (en) 2010-12-16
SG172859A1 (en) 2011-08-29
JP5583114B2 (ja) 2014-09-03
CN102272287A (zh) 2011-12-07
HK1159688A1 (en) 2012-08-03
JPWO2010101175A1 (ja) 2012-09-10
TWI501731B (zh) 2015-10-01

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