CN102245765B - 细胞移植 - Google Patents
细胞移植 Download PDFInfo
- Publication number
- CN102245765B CN102245765B CN200980150617.9A CN200980150617A CN102245765B CN 102245765 B CN102245765 B CN 102245765B CN 200980150617 A CN200980150617 A CN 200980150617A CN 102245765 B CN102245765 B CN 102245765B
- Authority
- CN
- China
- Prior art keywords
- cells
- polymer
- fat
- certain embodiments
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
- A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
- A61L2/18—Liquid substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Transplantation (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Botany (AREA)
- Polymers & Plastics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10702308P | 2008-10-21 | 2008-10-21 | |
| US61/107,023 | 2008-10-21 | ||
| PCT/US2009/005727 WO2010047793A2 (en) | 2008-10-21 | 2009-10-21 | Cell transplantation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102245765A CN102245765A (zh) | 2011-11-16 |
| CN102245765B true CN102245765B (zh) | 2015-01-07 |
Family
ID=42117712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200980150617.9A Active CN102245765B (zh) | 2008-10-21 | 2009-10-21 | 细胞移植 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8512695B2 (enExample) |
| EP (1) | EP2350274B1 (enExample) |
| JP (3) | JP5795961B2 (enExample) |
| CN (1) | CN102245765B (enExample) |
| AU (1) | AU2009308152B2 (enExample) |
| CA (1) | CA2744100C (enExample) |
| IL (1) | IL212471A (enExample) |
| WO (1) | WO2010047793A2 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2744100C (en) | 2008-10-21 | 2020-06-30 | The General Hospital Corporation | Cell transplantation |
| US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| CN108504539B (zh) * | 2010-08-06 | 2021-11-02 | 通用医院公司以麻省总医院名义经营 | 用于细胞处理相关应用的系统和设备 |
| US11090338B2 (en) | 2012-07-13 | 2021-08-17 | Lifecell Corporation | Methods for improved treatment of adipose tissue |
| US10549112B2 (en) | 2012-07-20 | 2020-02-04 | The General Hospital Corporation | Apparatus for tissue irradiation and methods and kits utilizing the same |
| WO2014015274A1 (en) | 2012-07-20 | 2014-01-23 | The General Hospital Corporation | Methods for tissue passivation |
| US12558316B2 (en) | 2013-03-13 | 2026-02-24 | University Of Miami | Methods and compositions for the treatment of epidermolysis bullosa |
| WO2014159662A1 (en) | 2013-03-13 | 2014-10-02 | University Of Miami | Method for isolation and purification of microvesicles from cell culture supernatants and biological fluids |
| CA3278502A1 (en) | 2013-07-18 | 2025-10-31 | The General Hospital Corporation | Vessel treatment systems, methods, and kits |
| US20150037436A1 (en) | 2013-07-30 | 2015-02-05 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| CA2929970C (en) | 2013-12-20 | 2020-05-12 | F. Hoffmann-La Roche Ag | Method of immobilizing a cell on a support using compounds comprising a polyethylene glycol moiety |
| JP6629736B2 (ja) | 2013-12-20 | 2020-01-15 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 1以上の疎水性ドメインおよびpeg部分を含む親水性ドメインを含む、細胞を結合するのに有用な化合物 |
| CN105917226B (zh) * | 2013-12-20 | 2018-06-01 | 豪夫迈·罗氏有限公司 | 包含两个或多个疏水结构域和一个含有peg部分的亲水结构域的化合物用于稳定细胞的用途 |
| JP6747748B2 (ja) | 2014-07-07 | 2020-08-26 | ライフラフト バイオサイエンシーズ,インコーポレイテッド | 長期循環物質のないポロクサマー組成物、その産生方法およびその使用 |
| WO2016154206A1 (en) * | 2015-03-26 | 2016-09-29 | Smith & Nephew, Inc. | Biopreservation medium and uses for biopreservation of biological materials |
| CA2986702C (en) | 2015-05-21 | 2023-04-04 | David Wang | Modified demineralized cortical bone fibers |
| US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
| JP7067744B2 (ja) * | 2016-06-30 | 2022-05-16 | 株式会社ヘリオス | 移植用媒体 |
| CN109257779B (zh) | 2017-07-14 | 2024-09-17 | 华为技术有限公司 | 网络切换方法及装置 |
| US20230190676A1 (en) * | 2020-07-09 | 2023-06-22 | Musc Foundation For Research Development | Methods of protecting cells from insults |
| US11229779B1 (en) * | 2020-08-12 | 2022-01-25 | Enrico Guarino | Method for skin ligament injection to obtain a lifting effect |
| AU2021327376A1 (en) | 2020-08-21 | 2023-04-20 | University Of Miami | Compositions and methods of treatment using microvesicles from bone marrow-derived mesenchymal stem cells |
| US11679198B2 (en) | 2021-04-28 | 2023-06-20 | Chopra Gryskiewicz, LLC | System and related methods for fat harvesting |
| GB2609940A (en) * | 2021-08-18 | 2023-02-22 | Life Science Group Ltd | Cell transport and storage composition and method |
| EP4511045A1 (en) | 2022-04-19 | 2025-02-26 | University of Miami | Compositions comprising microvesicles for use in the prevention and treatment of graft versus host disease |
| CN114908044A (zh) * | 2022-05-13 | 2022-08-16 | 北京大学第三医院(北京大学第三临床医学院) | 一种富含外泌体的微颗粒脂肪片段提纯方法及其乳化器 |
| WO2025265118A1 (en) * | 2024-06-21 | 2025-12-26 | Trustees Of Tufts College | Use of emulsifiers and amphiphilic agents to increase yields during cell isolations |
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| WO2006044738A2 (en) * | 2004-10-18 | 2006-04-27 | Maroon Biotech Corporation | Methods and compositions for treatment of free radical injury |
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| EP2350274A2 (en) | 2011-08-03 |
| US8512695B2 (en) | 2013-08-20 |
| EP2350274A4 (en) | 2014-01-08 |
| WO2010047793A3 (en) | 2010-08-05 |
| CN102245765A (zh) | 2011-11-16 |
| JP2016185962A (ja) | 2016-10-27 |
| AU2009308152B2 (en) | 2015-05-21 |
| US20100104542A1 (en) | 2010-04-29 |
| US9730963B2 (en) | 2017-08-15 |
| AU2009308152A1 (en) | 2010-04-29 |
| JP5795961B2 (ja) | 2015-10-14 |
| IL212471A0 (en) | 2011-06-30 |
| IL212471A (en) | 2015-05-31 |
| JP2014208654A (ja) | 2014-11-06 |
| JP2012506430A (ja) | 2012-03-15 |
| BRPI0919919A2 (pt) | 2017-05-30 |
| US20130336936A1 (en) | 2013-12-19 |
| JP5933629B2 (ja) | 2016-06-15 |
| EP2350274B1 (en) | 2019-01-23 |
| CA2744100A1 (en) | 2010-04-29 |
| WO2010047793A2 (en) | 2010-04-29 |
| CA2744100C (en) | 2020-06-30 |
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