CN102228668A - Chinese medicinal composition for treating deficiency-cold vomiting of pregnancy and preparation method thereof - Google Patents

Abstract

The invention relates to a Chinese medicinal composition for treating deficiency-cold vomiting of pregnancy and a preparation method thereof. The Chinese medicinal composition comprises the following components in part by mass: 20 to 30 parts of medicinal evodia fruit, 20 to 30 parts of szechuan tangshen root, 20 to 30 parts of ginger-processed pinellia tuber, 10 to 20 parts of ginseng, 10 to 20 parts of officinal magnolia bark, 10 to 20 parts of white paeony root, 10 to 20 parts of Chinese date and 10 to 20 parts of dried ginger. The Chinese medicinal composition can treat the deficiency-cold vomiting of pregnancy effectively, is quick and stable in response and does not have obvious toxic or side effect. By clinical application, the obvious clinical effect is obtained.

Description

A kind of Chinese medicine composition for the treatment of the deficiency and coldness vomiting during pregnancy and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of the deficiency and coldness vomiting during pregnancy, belong to pure Chinese herbal medicine.The preparation method that also relates to described Chinese medicine composition.

Background technology

The deficiency and coldness vomiting during pregnancy is meant in the pregnant process because the vomiting that Deficiency and coldness of spleen and stomach causes.At present the most antiemetic effects of the medicine that uses are poor, in addition have bigger toxic and side effects arranged, and cost height can not be satisfactory aspect therapeutic effect.

Summary of the invention

Technical problem to be solved by this invention is, a kind of Chinese medicine composition for the treatment of the deficiency and coldness vomiting during pregnancy and preparation method thereof is provided, by warming the liver and stomach, expelling cold pathogen and lowering adverse QI, fundamentally treat the deficiency and coldness vomiting during pregnancy, to overcome the defective of existing such disease medicine of treatment.

It is as follows that the present invention solves the problems of the technologies described above the technical scheme that is adopted:

A kind of Chinese medicine composition for the treatment of the deficiency and coldness vomiting during pregnancy is characterized in that its prescription is: Fructus Evodiae 20-30 part, Radix Codonopsis 20-30 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20-30 part, Radix Ginseng 10-20 part, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China 10-20 part, Radix Paeoniae Alba 10-20 part, Fructus Jujubae 10-20 part, Rhizoma Zingiberis 10-20 part, described part refers to mass parts.

Preferred prescription is: 25 parts of Fructus Evodiaes, 25 parts of Radix Codonopsis, 25 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 15 parts of Radix Ginsengs, 15 parts of CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, 15 parts of the Radix Paeoniae Albas, 15 parts in Fructus Jujubae, 15 parts of Rhizoma Zingiberiss.

The preparation method of the Chinese medicine composition of described treatment deficiency and coldness vomiting during pregnancy is characterized in that:

(1), get the Fructus Evodiae of described ratio, Radix Codonopsis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Ginseng, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, the Radix Paeoniae Alba, Fructus Jujubae, the Rhizoma Zingiberis mix homogeneously is ground into 80 purpose granules;

(2), with above-mentioned granule in 130-135 ℃ the baking 6-10 minute, be cooled to room temperature;

(3), with (2) step made mixture be ball with honey, every ball weigh 3 the gram.

Instructions about how to take medicine and usage: oral, every clothes 1 ball, every day 3 times.

The main Chinese herbal medicine of prescription of the present invention is according to traditional medicine and modern medicine analysis, and the property of medicine and pharmacological action are as follows:

Fructus Evodiae: meridian distribution of property and flavor: heat; Hot, bitter; Return liver, spleen, stomach, kidney channel; Mild toxicity.Function cures mainly: dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.Be used for headache due to JUE YIN disorder, colic of cold type stomachache, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, abdominal distention, the vomiting acid regurgitation is had loose bowels just before dawn; The external treatment aphtha, hypertension.

Radix Codonopsis: meridian distribution of property and flavor: flat; Sweet; Return spleen, lung meridian.Function cures mainly: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.Be used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool is breathed heavily empty cough, and interior-heat is quenched one's thirst.

Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens): nature and flavor with return through: hot, warm; Poisonous.Return spleen, stomach, lung meridian.Function with cure mainly: stopping nausea and vomiting by lowering the adverse flow of QI.Be used to vomit regurgitation, breast gastral cavity painful abdominal mass is vexed, globus hystericus.

Radix Ginseng: meridian distribution of property and flavor: tepor; Sweet, little hardship; GUIXIN, lung, spleen channel.Function cures mainly: strongly invigorating primordial QI, and multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung promotes the production of body fluid, and calms the nerves.Be used for weak body and prostration, the cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, prolonged illness weakness with emaciation, palpitation with fear insomnia, sexual impotence cold womb; Heart failure, cardiogenic shock.

CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China meridian distribution of property and flavor: temperature; Bitter, hot; Return spleen, lung, stomach, large intestine channel.Function cures mainly: the dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is removed full.Be used for the humidity hysteresis damaging the spleen and stomach, the gastral cavity painful abdominal mass is vomited and diarrhoea, stagnation of QI due to dyspepsia, and abdominal distention constipation, phlegm retention is breathed with cough.

The Radix Paeoniae Alba: meridian distribution of property and flavor: be slightly cold; Bitter, acid, sweet; Return liver, spleen channel.Function cures mainly: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.It is dizzy to be used to have a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.

Fructus Jujubae: meridian distribution of property and flavor: temperature; Sweet; Return spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.Be used for insufficiency of the spleen lack of appetite, weak loose stool, the married woman is dirty dry.

Rhizoma Zingiberis: meridian distribution of property and flavor: heat; Hot; Return spleen, stomach, kidney, the heart, lung meridian.Function cures mainly: warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, the dampness expectorant.Be used for coldness and pain in the epigastrium, vomiting is had loose bowels, cold extremities faint pulse, phlegm retention cough with asthma.

The Fang Xieyu good effect:

The traditional Chinese medical science is thought: the evil cold enemy intrusion or invasion cloudy Liver Channel of fainting, and yin-cold excess, hypoactivity of spleen-YANG, stomach-QI being unable to descend normally, so the gas superinverse of turbid yin, sputum rises thereupon, so retch, salivation; Insufficiency of stomach has cold, the gas superinverse of YIN-cold, and cause vomiting; The gas superinverse of gestation aggravation YIN-cold, mechanism of qi is obstructed, so vomiting increases the weight of.Fructus Evodiae warming the liver and stomach, cold expelling the turbid descending are main among the present invention, Radix Codonopsis, Radix Ginseng invigorating primordial QI, the CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China therapeutic method to keep the adverse QI flowing downwards is removed full, and the Radix Paeoniae Alba is separated the painful bitter taste of abdomen, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) ends vomiting usually, the Fructus Jujubae of assistant, Rhizoma Zingiberis, warming the liver and stomach, all medicines share, treat the deficiency and coldness vomiting during pregnancy effectively, and effect is fast, and is steady, no obvious toxic and side effects.Obtained tangible clinical effectiveness through clinical practice.

The specific embodiment

Further specify the present invention below in conjunction with concrete preparation example.

Prescription example one:

The set of dispense ratio is: 20 parts of Fructus Evodiaes, 20 parts of Radix Codonopsis, 20 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 10 parts of Radix Ginsengs, 10 parts of CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, 10 parts of the Radix Paeoniae Albas, 10 parts in Fructus Jujubae, 10 parts of Rhizoma Zingiberiss.

Preparation method:

(1) get 20 parts of Fructus Evodiaes, 20 parts of Radix Codonopsis, 20 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 10 parts of Radix Ginsengs, 10 parts of CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, 10 parts of the Radix Paeoniae Albas, 10 parts in Fructus Jujubae, 10 parts of mix homogeneously of Rhizoma Zingiberis are ground into 80 purpose granules.

(2) with above-mentioned granule in 130-135 ℃ the baking 6-10 minute, be cooled to room temperature.

(3) be ball with honey with (2) made mixture, every ball weighs 3 grams.

Instructions about how to take medicine and usage: oral, every clothes 1 ball, every day 3 times.

Prescription example two:

The set of dispense ratio is: 25 parts of Fructus Evodiaes, 25 parts of Radix Codonopsis, 25 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 15 parts of Radix Ginsengs, 115 parts of CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, 15 parts of the Radix Paeoniae Albas, 15 parts in Fructus Jujubae, 15 parts of Rhizoma Zingiberiss.

Preparation method:

(1) get 25 parts of Fructus Evodiaes, 25 parts of Radix Codonopsis, 25 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 15 parts of Radix Ginsengs, 115 parts of CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, 15 parts of the Radix Paeoniae Albas, 15 parts in Fructus Jujubae, 15 parts of mix homogeneously of Rhizoma Zingiberis are ground into 80 purpose granules.

(2) with above-mentioned granule in 130-135 ℃ the baking 6-10 minute, be cooled to room temperature.

(3) be ball with honey with (2) made mixture, every ball weighs 3 grams.

Instructions about how to take medicine and usage are with embodiment one.

Prescription example three:

The set of dispense ratio is: 30 parts of Fructus Evodiaes, 30 parts of Radix Codonopsis, 30 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 20 parts of Radix Ginsengs, 20 parts of CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, 20 parts of the Radix Paeoniae Albas, 20 parts in Fructus Jujubae, 20 parts of Rhizoma Zingiberiss.

Preparation method:

(1) get 30 parts of Fructus Evodiaes, 30 parts of Radix Codonopsis, 30 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 20 parts of Radix Ginsengs, 20 parts of CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, 20 parts of the Radix Paeoniae Albas, 20 parts in Fructus Jujubae, 20 parts of mix homogeneously of Rhizoma Zingiberis are ground into 80 purpose granules.

2) with above-mentioned granule in 130-135 ℃ the baking 6-10 minute, be cooled to room temperature.

(3) be ball with honey with (2) made mixture, every ball weighs 3 grams.

Instructions about how to take medicine and usage are with embodiment one.

It below is clinical report

From year February in February, 2008 to 2011, the inventor uses the present invention's example two treatment deficiency and coldness vomiting during pregnancy 75 examples of writing out a prescription in Yantai Zhifu District the People's Hospital, and treats 30 examples and carry out controlled observation with using vitamin B6 the same period, receives better effects, now is reported as follows.

1, clinical data

Physical data is observed case totally 105 examples, is divided into 2 groups at random.Women 75 examples are organized in treatment; (26 ± 2 years old age; The course of disease (16 ± 2) sky; Matched group woman 30 examples; Age 26 ± 2) year; The course of disease (16 ± 2) sky.

Two groups of physical data are learned processing by statistics, and there are no significant that meaning (P＞0.05) has comparability for difference.

2, Therapeutic Method

2.1 matched group adopts oral 75 milligrams of vitamin Bies, every day 2 times, continues the treatment of three weeks.

2.2 the treatment group adopts every clothes 1 ball of oral medicine of the present invention, every day 2 times, continues the treatment of three weeks.

2.3 feel sick before and after the observation item treatment, vomiting, feed, hematuria situation,

2.4 statistical method adopts the SPSS statistical software to analyze.

3, criterion of therapeutical effect and therapeutic outcome

Criterion of therapeutical effect is with reference to relevant criterion of therapeutical effect in " disease of tcm judgement criterion of therapeutical effect ".Recovery from illness: clinical symptoms all disappears, and the test chamber inspection is normal.Take a turn for the better: clinical symptom relief, lab testing improve or are normal.Invalid: clinical symptoms does not have being clearly better or increases the weight of.

Therapeutic outcome:

Two groups of clinical efficacies relatively see Table 1.Total effective rate treatment group is 87.9%, and matched group is 76.6%, 2 group and compares that difference has significance meaning (P＜0.05).

Table 1 liang group clinical efficacy relatively

Group n improvement recovery from illness invalid total effective rate (%)

Treatment organizes 75 13 (17.3%) 53 (70.6%) 9 (12%) 87.9%

Matched group 302 (6.6%) 21 (70%) 7 (23.3%) 76.6%

With preceding relatively ※ P＜0.01 of treatment; With comparison after the treatment of control group, Δ P＜0.01.

This shows that medicine of the present invention is better than other medicines for treatment deficiency and coldness vomiting during pregnancy effect, cures the effective percentage height, is the medicine of ideal treatment deficiency and coldness vomiting during pregnancy.

Claims (3)

1. a Chinese medicine composition for the treatment of the deficiency and coldness vomiting during pregnancy is characterized in that its prescription is: Fructus Evodiae 20-30 part, Radix Codonopsis 20-30 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20-30 part, Radix Ginseng 10-20 part, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China 10-20 part, Radix Paeoniae Alba 10-20 part, Fructus Jujubae 10-20 part, Rhizoma Zingiberis 10-20 part, described part refers to mass parts.

2. the Chinese medicine composition of treatment deficiency and coldness vomiting during pregnancy as claimed in claim 1 is characterized in that its prescription is: 25 parts of Fructus Evodiaes, 25 parts of Radix Codonopsis, 25 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 15 parts of Radix Ginsengs, 15 parts of CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, 15 parts of the Radix Paeoniae Albas, 15 parts in Fructus Jujubae, 15 parts of Rhizoma Zingiberiss.

3. the preparation method of the Chinese medicine composition of treatment deficiency and coldness vomiting during pregnancy as claimed in claim 1 or 2 is characterized in that:

(1), get the Fructus Evodiae of described ratio, Radix Codonopsis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Ginseng, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, the Radix Paeoniae Alba, Fructus Jujubae, the Rhizoma Zingiberis mix homogeneously is ground into 80 purpose granules;

(2), with above-mentioned granule in 130-135 ℃ the baking 6-10 minute, be cooled to room temperature;

(3), with (2) step made mixture be ball with honey, every ball weigh 3 the gram.