CN102228652B - Chinese medicinal composition for treating chronic peritonitis and preparation method thereof - Google Patents

Abstract

The invention discloses a Chinese medicinal composition for treating chronic peritonitis and a preparation method thereof. According to a prescription, the Chinese medicinal composition comprises the following components in parts by mass: 30-50 parts of wine-decocted peony, 20-30 parts of cassia twig, 20-30 parts of cauterized licorice root, 10-20 parts of Chinese date, 30-50 parts of malt syrup,10-20 parts of katsumade galangal seed, 10-20 parts of tangerine peel, 10-20 parts of costus root and 10-20 parts of Chinese pulsatilla root. The medicine can be used for effectively treating the chronic peritonitis, has quick and stable response and does not have obvious toxic or side effect. Clinical application shows that the medicine has an obvious clinical effect.

Description

Chinese medicine composition of treatment chronic peritonitis and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine composition of treating chronic peritonitis, belong to pure Chinese herbal medicine.Also relate to its preparation method.

Background technology

Chronic peritonitis is meant the disease of the long-term pain inflammation of the peritoneum that is caused by a variety of causes, normally is transformed by acute peritonitis.The most weak effects of the medicine that uses at present, in addition have bigger toxic and side effects arranged; Operative treatment has a big risk, and cost is high, and the ubiquity sequela can not be satisfactory aspect therapeutic effect.

Summary of the invention

Technical problem to be solved by this invention is, a kind of Chinese medicine composition of treating chronic peritonitis and preparation method thereof is provided, and dispels cold through tonify deficiency, and antibacterial relieves the pain, and fundamentally treats chronic peritonitis, to overcome the defective of existing such disease medicine of treatment and method.

It is following that the present invention solves the problems of the technologies described above the technical scheme that is adopted:

A kind of Chinese medicine composition of treating chronic peritonitis is characterized in that its prescription is: Radix Paeoniae Alba preparata medicine 30-50 part, Ramulus Cinnamomi 20-30 part; Radix Glycyrrhizae Preparata 20-30 part, Fructus Jujubae 10-20 part, maltose 30-50 part; Semen Alpiniae Katsumadai 10-20 part, Pericarpium Citri Reticulatae 10-20 part, Radix Aucklandiae 10-20 part; Radix Pulsatillae 10-20 part, described part refers to mass parts.

Preferred prescription is: 40 parts of Radix Paeoniae Alba preparata medicines, 25 parts of Ramulus Cinnamomi, 25 parts of Radix Glycyrrhizae Preparatas, 15 parts in Fructus Jujubae, 40 parts of maltoses, 15 parts of Semen Alpiniae Katsumadai, 15 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 15 parts of the Radix Pulsatillaes.

The method for preparing of the Chinese medicine composition of said treatment chronic peritonitis is characterized in that:

(1), get the Radix Paeoniae Alba preparata medicine of said ratio, Ramulus Cinnamomi, Radix Glycyrrhizae Preparata, Fructus Jujubae, maltose, Semen Alpiniae Katsumadai, Pericarpium Citri Reticulatae, the Radix Aucklandiae, Radix Pulsatillae mix homogeneously is ground into 80 purpose granules.

(2), with above-mentioned granule in 130-135 ℃ the baking 6-10 minute, be cooled to room temperature.

(3), with (2) step made mixture be ball with honey, every ball weigh 8 the gram.

Instructions about how to take medicine and usage: oral, every clothes 1 ball, every day 3 times.

The main Chinese herbal medicine of prescription of the present invention is according to traditional medicine and modern medicine analysis, and the property of medicine and pharmacological action are following:

Radix Paeoniae Alba preparata medicine: meridian distribution of property and flavor: be slightly cold; Bitter, acid, sweet; Return liver, spleen channel.Function cures mainly: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.It is dizzy to be used to have a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.

Ramulus Cinnamomi: meridian distribution of property and flavor: temperature; Hot, sweet; GUIXIN, lung, urinary bladder channel.Function cures mainly: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI.Be used for anemofrigid cold, wrist abdomen cold type of pain, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.

Radix Glycyrrhizae Preparata: meridian distribution of property and flavor: flat; Sweet; GUIXIN, lung, spleen, stomach warp. function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

Fructus Jujubae: meridian distribution of property and flavor: temperature; Sweet; Return spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.Be used for insufficiency of the spleen lack of appetite, weak loose stool, the married woman is dirty dry.

Rhizoma Zingiberis: meridian distribution of property and flavor: heat; Hot; Return spleen, stomach, kidney, the heart, lung meridian.Function cures mainly: warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, the dampness expectorant.Be used for coldness and pain in the epigastrium, vomiting is had loose bowels, cold extremities faint pulse, phlegm retention cough with asthma.

Maltose: sweet in the mouth, warm in nature.Ability invigorating middle warmer emergency, nourishing the lung to arrest cough, detoxifcation.Dissolve drink, go into decoction, hold in the mouth or the eyes pharynx, or go into confection etc.

Semen Alpiniae Katsumadai: meridian distribution of property and flavor: temperature; Hot; Return spleen, stomach warp. function cures mainly: drying damp and strengthening spleen, the stomach warming preventing or arresting vomiting.Be used for the cold-damp internal resistance, distension and fullness in the abdomen cold type of pain, belch vomiting, anorexia.

Pericarpium Citri Reticulatae: meridian distribution of property and flavor: temperature; Hot, bitter; Return spleen, lung meridian. function cures mainly: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Be used for fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.

The Radix Aucklandiae: meridian distribution of property and flavor: temperature; Hot, bitter; Return lung, stomach, large intestine, gallbladder, tri-jiao channel. function cures mainly: promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.Be used for breast gastral cavity distending pain, heavy behind the dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).Stomachache is used to have loose bowels.

The Radix Pulsatillae: meridian distribution of property and flavor: cold; Bitter; Return stomach, large intestine channel. function cures mainly: heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery.Be used for toxic-heat and blood stasis, pudendal pruritus leukorrhagia, amebic dysentery.

The Fang Xieyu good effect:

The traditional Chinese medical science is thought: peritonitis is yin-cold excess, and cold bringing about contraction is so abdomen is painful more than, also or hydrops, inflammation.During the maltose tonify deficiency is built among the present invention, and can relieving spasm to stop pain, join Ramulus Cinnamomi, Radix Glycyrrhizae can be controlled middle tonify deficiency, closes Radix Paeoniae, Radix Glycyrrhizae, can relieve the pain with the lining emergency, but again with Fructus Jujubae, Rhizoma Zingiberis Recens not only strengthening the spleen and stomach but also can manage jointly and defend; Fructus Amomi Rotundus, Pericarpium Citri Reticulatae, Radix Aucklandiae stomach warming, flat gas, change are expired; Radix Pulsatillae bactericidal antiphlogistic.Compatibility like this, middle burnt yang-energy must be answered, and YIN-cold is from diffusing, and stomachache is certainly only.The all medicines of Chinese herbaceous peony share, and treat chronic peritonitis and effect effectively soon, and are steady, no obvious toxic and side effects.Obtained tangible clinical effectiveness through clinical practice.

The specific embodiment

Further specify the present invention below in conjunction with concrete preparation instance.

Prescription instance one:

The set of dispense ratio is: 30 parts of Radix Paeoniae Alba preparata medicines, 20 parts of Ramulus Cinnamomi, 20 parts of Radix Glycyrrhizae Preparatas, 10 parts in Fructus Jujubae, 30 parts of maltoses, 10 parts of Semen Alpiniae Katsumadai, 10 parts of Pericarpium Citri Reticulataes, 10 parts of the Radix Aucklandiae, 10 parts of the Radix Pulsatillaes.

Method for preparing:

(1) get 30 parts of Radix Paeoniae Alba preparata medicines, 20 parts of Ramulus Cinnamomi, 20 parts of Radix Glycyrrhizae Preparatas, 10 parts in Fructus Jujubae, 30 parts of maltoses, 10 parts of Semen Alpiniae Katsumadai, 10 parts of Pericarpium Citri Reticulataes, 10 parts of the Radix Aucklandiae, 10 parts of mix homogeneously of the Radix Pulsatillae are ground into 80 purpose granules.

(2) with above-mentioned granule in 130-135 ℃ the baking 6-10 minute, be cooled to room temperature.

(3) be ball with honey with (2) made mixture, every ball weighs 8 grams.

Instructions about how to take medicine and usage: oral, every clothes 1 ball, every day 3 times.

Prescription instance two:

The set of dispense ratio is: 40 parts of Radix Paeoniae Alba preparata medicines, 25 parts of Ramulus Cinnamomi, 25 parts of Radix Glycyrrhizae Preparatas, 15 parts in Fructus Jujubae, 40 parts of maltoses, 15 parts of Semen Alpiniae Katsumadai, 15 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 15 parts of the Radix Pulsatillaes.

Method for preparing:

(1) get 40 parts of Radix Paeoniae Alba preparata medicines, 25 parts of Ramulus Cinnamomi, 25 parts of Radix Glycyrrhizae Preparatas, 15 parts in Fructus Jujubae, 40 parts of maltoses, 15 parts of Semen Alpiniae Katsumadai, 15 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 15 parts of mix homogeneously of the Radix Pulsatillae are ground into 80 purpose granules.

(2) with above-mentioned granule in 130-135 ℃ the baking 6-10 minute, be cooled to room temperature.

(3) be ball with honey with (2) made mixture, every ball weighs 8 grams.

Instructions about how to take medicine and usage are with embodiment one.

Prescription instance three:

The set of dispense ratio is: 50 parts of Radix Paeoniae Alba preparata medicines, 30 parts of Ramulus Cinnamomi, 30 parts of Radix Glycyrrhizae Preparatas, 20 parts in Fructus Jujubae, 50 parts of maltoses, 20 parts of Semen Alpiniae Katsumadai, 20 parts of Pericarpium Citri Reticulataes, 20 parts of the Radix Aucklandiae, 20 parts of the Radix Pulsatillaes.

Method for preparing:

(1) get 50 parts of Radix Paeoniae Alba preparata medicines, 30 parts of Ramulus Cinnamomi, 30 parts of Radix Glycyrrhizae Preparatas, 20 parts in Fructus Jujubae, 50 parts of maltoses, 20 parts of Semen Alpiniae Katsumadai, 20 parts of Pericarpium Citri Reticulataes, 20 parts of the Radix Aucklandiae, 20 parts of mix homogeneously of the Radix Pulsatillae are ground into 80 purpose granules.

2) with above-mentioned granule in 130-135 ℃ the baking 6-10 minute, be cooled to room temperature.

(3) be ball with honey with (2) made mixture, every ball weighs 8 grams.

Instructions about how to take medicine and usage are with embodiment one.

It below is clinical report

From year February in February, 2008 to 2011; The Fushan District the People's Hospital uses the present invention's instance two treatment chronic peritonitiss 75 examples of writing out a prescription to the inventor in Yantai; And with the same period application of metronidazole add amino benzylpcnicillin and treat 30 examples and carry out controlled observation, receive better effects, existing report as follows.

Clinical data

Physical data is observed case totally 105 examples, is divided into 2 groups at random.Women 35 examples are organized in treatment, male 35 examples, totally 75 examples; Year at age (36 ± 2); The course of disease (16 ± 2) sky.Matched group woman 10 examples, male 20 examples, totally 30 examples; Year at age (33 ± 3); The course of disease (16 ± 2) sky.Two groups of physical data are through statistical procedures, and there are no significant that meaning (P＞0.05) has comparability for difference.

Therapeutic Method

Matched group adopts metronidazole to add amino benzylpcnicillin drop, every day 2 times, continues the treatment of 1 week.

The treatment group adopts every clothes 1 ball of oral medicine of the present invention, every day 3 times, continues the treatment of 1 week.

Stomachache before and after the observation item treatment, feel sick, vomiting, feed, hematuria, the body temperature situation,

Statistical method adopts the SPSS statistical software to analyze.

Criterion of therapeutical effect and therapeutic outcome

Criterion of therapeutical effect is with reference to relevant criterion of therapeutical effect in " disease of tcm judgement criterion of therapeutical effect ".Recovery from illness: clinical symptoms all disappears, and the test chamber inspection is normal.Take a turn for the better: clinical symptom relief, lab testing improve or are normal.Invalid: clinical symptoms does not have being clearly better or increases the weight of.

Therapeutic outcome:

Two groups of clinical efficacies are relatively seen table 1.Total effective rate treatment group is 87.9%, and matched group is 76.6%, 2 group and compares that difference has significance meaning (P＜0.05).

Table 1 liang group clinical efficacy relatively

With preceding relatively ※ P＜0.01 of treatment; With comparison after the treatment of control group, Δ P＜0.01.

This shows that medicine of the present invention is superior to other medicines for treatment chronic peritonitis effect, cures the effective percentage height, is the medicine of ideal treatment chronic peritonitis.

Claims (3)

1. a Chinese medicine composition of treating chronic peritonitis is characterized in that this Chinese medicine is: Radix Paeoniae Alba preparata medicine 30-50 part, Ramulus Cinnamomi 20-30 part; Radix Glycyrrhizae Preparata 20-30 part, Fructus Jujubae 10-20 part, maltose 30-50 part; Semen Alpiniae Katsumadai 10-20 part, Pericarpium Citri Reticulatae 10-20 part, Radix Aucklandiae 10-20 part; Radix Pulsatillae 10-20 part, described part refers to mass parts.

2. a kind of Chinese medicine composition of treating chronic peritonitis as claimed in claim 1 is characterized in that this Chinese medicine is: 40 parts of Radix Paeoniae Alba preparata medicines, 25 parts of Ramulus Cinnamomi, 25 parts of Radix Glycyrrhizae Preparatas; 15 parts in Fructus Jujubae, 40 parts of maltoses, 15 parts of Semen Alpiniae Katsumadai; 15 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 15 parts of the Radix Pulsatillaes.

3. like the method for preparing of the Chinese medicine composition of claim 1 and 2 described treatment chronic peritonitiss, it is characterized in that:

(1), get the Radix Paeoniae Alba preparata medicine of said ratio, Ramulus Cinnamomi, Radix Glycyrrhizae Preparata, Fructus Jujubae, maltose, Semen Alpiniae Katsumadai, Pericarpium Citri Reticulatae, the Radix Aucklandiae, Radix Pulsatillae mix homogeneously is ground into 80 purpose granules;

(2), with above-mentioned granule in 130-135 ℃ the baking 6-10 minute, be cooled to room temperature;

(3), with (2) step made mixture be ball with honey, every ball weigh 8 the gram.