CN101041052B

CN101041052B - Chinese traditional medicine compound took orally for treating Raynand's disease

Info

Publication number: CN101041052B
Application number: CN2007100154086A
Authority: CN
Inventors: 于振鹏
Original assignee: Individual
Current assignee: Individual
Priority date: 2007-04-20
Filing date: 2007-04-20
Publication date: 2010-10-06
Anticipated expiration: 2027-04-20
Also published as: CN101041052A

Abstract

The invention discloses an oral administration pharmaceutical composition for treating Raynaud's disease, wherein the active constituents include the following raw material herbs (by weight portion): astragalus root 20, cassia twig 10, Chinese angelica root 15, radix paeoniae rubrathe 10, root of herbaceous peony 10, Ligusticum wallichii 10, licorice root 10, asaryl 4, peach kernels 10, evodia rutaecarpa 3, atractylodes rhizome 10, prepared aconite root 10 and dried ginger 11. The medicament should be decocted in water for the oral dose.

Description

A kind of Chinese medicine composition of took orally for treating Raynand's disease

Technical field

The present invention relates to a kind of Chinese medicine composition of took orally for treating Raynand's disease, belong to the field of Chinese medicines.

Background technology

After Raynand's disease is the cold or emotional distress of a kind of chance, cause that with strong contraction of paroxysmal acra small artery acro-ischemia is the disease of characteristics, claims the acra vasospastic disease again.Acra skin becomes livid purplely by pale during outbreak, then transfers flushing to.Primary disease belongs to the traditional Chinese medical science " deadly cold hand and foot " and categories such as " arthromyodynias "." concise exposition on febrile disease " as Cheng Wuji has more detailed description to this sick cause of disease, pathogenesis and clinical manifestation, think " the typhoid fever person of fainting, the how bright person of fainting, also cold, be far more than that cold limbs is also.Through saying: the person of fainting, YIN QI and YANG QI circulating out of order is just for fainting.The person of fainting, the limbs with coldness is also, the meaning YANG QI falling into the interior, the contrary volt of steam, and brothers are also cold for it ".

The cause of disease of Raynaud disease it be unclear that so far; but cold, damage and medicine irritation are the reasons that causes the local vascular spasm; it also is key factor that the unusual or polypeptide of vasodilation lacks; the vasomotor nerve maincenter of oblongata is a former adjusting maincenter of skin, muscle vascular shrink tension; some zone of hypothalamus and cortex also is an important adjusting part; if these positions also can cause the generation of primary disease undermined.Because the neural characteristic distributions of peripheral vessels though promptly sympathetic nerve is the vasoconstrictor nerve fiber, is again the vasodilator nerve fiber in some zone, and hands and foot only have the vasoconstrictor nerve fiber, get involved so vasospasm disease is common in extremity.Except that above situation, the someone thinks the nervus centralis dysfunction, and sympathetic hyperfunction can cause primary disease.In addition, heredity, immune dysfunction and the arteriolar defective of congenital acra also can cause primary disease.

The method of treatment Raynand's disease mainly contains at present:

The western modern medicine treatment: (1) naturopathy is used cold and heat succeed each other hydrotherapy, phototherapy, direct current electrotherapy and massotherapy; (2) Drug therapy medicament for expanding vascellum; (3) surgical intervention operative treatment.

Chinese medicine: (1) internal treatment; (2) external treatment; (3) acupuncture treatment.

These methods have all played certain therapeutical effect on treating at present, but have the surgery cost costliness, and are dangerous big, the low deficiency that waits of versatility.Domestic a large amount of utilization Chinese medicine is cured primary disease, and method is different, has obtained remarkable progress, but not ideal.

Summary of the invention

The present invention has overcome the deficiency of above-mentioned treatment Raynand's disease, and a kind of Chinese medicine composition of took orally for treating Raynand's disease is provided, and all selects natural Chinese medicinal herb for use, improves the therapeutic effect of Raynand's disease.

Technical scheme of the present invention is: the Chinese medicine composition of this kind took orally for treating Raynand's disease, it is characterized in that, the crude drug of making active ingredient by following weight portion is: the Radix Astragali 20, Ramulus Cinnamomi 10, Radix Angelicae Sinensis 15, Radix Paeoniae Rubra 10, the Radix Paeoniae Alba 10, Rhizoma Chuanxiong 10, Radix Glycyrrhizae 10, Herba Asari 4, Semen Persicae 10, Fructus Evodiae 3, Rhizoma Atractylodis 10, Radix Aconiti Lateralis Preparata 10 and Rhizoma Zingiberis 11.

During compounding pharmaceutical, the said medicine impurities in raw materials is removed, put into pot successively, add 500 ml waters, decoction gets final product half an hour, and is oral, sooner or later each potion.Ten days is a course of treatment.

Pharmacological action:

The Radix Astragali: tonifying Qi and lifting yang, hemostasis by invigorating QI, the QI invigorating row stagnates, blood stasis removing eliminating stagnation, benefiting QI for strengthening the superficies, QI invigorating tonifying YIN, inducing diuresis to remove edema, warming the interior cold expelling, pus expelling by strengthening vital QI granulation promoting, strong body constitution, life lengthening.

Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.Be used for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.

Radix Angelicae Sinensis: benefiting blood and regulating blood circulation, menstruction regulating and pain relieving is moisturized laxation.

The Radix Paeoniae Alba: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.

Radix Paeoniae Rubra: clearing away heat and cooling blood, eliminating stasis to stop pain.

Radix Glycyrrhizae: and middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.Control weakness of the spleen and stomach, lack of appetite, the stomachache loose stool, the overstrain heating, the consumptive lung disease cough, cardiopalmus is fainted from fear; Give birth to usefulness, control laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.

Rhizoma Chuanxiong: air to open is strongly fragrant, dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain.Control air-cooled headache, revolve dizzyly, the hypochondriac pain abdomen is painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.

Rhizoma Atractylodis: spleen invigorating, dampness, resolving depression, ward off dirty, expelling cold and relieving exterior syndrome.Control wet the Sheng and be stranded spleen, the asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting is had loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens flu, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.

Semen Persicae: blood stasis removing and clots absorbing, moisturize laxation.Control amenorrhea, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.

Fructus Evodiae: dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.Be used for headache due to JUE YIN disorder, colic of cold type stomachache, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, abdominal distention, the vomiting acid regurgitation is had loose bowels the external treatment aphtha just before dawn; Hypertension.

Radix Aconiti Lateralis Preparata: recuperating depleted YANG is mended fire, dispelling cold and removing dampness.Control excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhea is fainted contrary, trusted subordinate's cold type of pain, the splenic diarrhea cold-dysentery, beriberi edema, children's's intermittent infantile convulsion, anemofrigid-damp arthralgia, contracture, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses.

Rhizoma Zingiberis: warming middle-JIAO is by cold, and recuperating depleted YANG is promoted blood circulation.Control trusted subordinate's cold type of pain, vomit and diarrhoea, the cold extremities faint pulse, cold fluid-retention is breathed with cough, anemofrigid-damp arthralgia, yang deficiency is told, hematochezia.

Herba Asari: dispel the wind, cold expelling, row water is had one's ideas straightened out.Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.

After the present invention mixed said medicine, its drug effect had synergism, in the Raynand's disease therapeutic process, has obtained remarkable result.The Chinese medicine composition of this kind took orally for treating Raynand's disease reaches 81% through clinical 100 example checking effective percentage.

Model case:

Example one: Mrs Gao, 36 years old, the patient fell ill before 2 years to both hands wrist place, when the state of an illness is the most serious, soaked with the warm water, still needed 1 many hours ability to alleviate.Through examination in hospital is Raynaud disease.Take various Chinese-western medicine preparations, DeGrain, after upon somebody's introduction, begin to take the Chinese medicine composition of this kind took orally for treating Raynand's disease, after medication course of treatment obviously sensation take a turn for the better, promptly accuse recovery from illness after three courses of treatment, for after treatment continues course of treatment of medication again.So far not recurrence.

Example two: Mrs Ceng, 21 years old, patient's readme the cold both hands colour of skin occurred meeting and loses color before 3 years, the then cyanosis that continues, flushing recovers normal after chance is warm gradually, and simultaneously with numb distending pain, autumn and winter season shows effect more frequent.One week of traditional Chinese medicine composition for treating back patient's attack times of taking this kind took orally for treating Raynand's disease reduces, and numb distending pain is sent out cold and alleviated.The both hands feeling of numbness disappears after January, and color is more ruddy, still has fear of cold. and strengthen living nursing, regulate diet.Patient's both hands do not have feeling of numbness after March, and the skin temperature is normal, and color is ruddy, meet coldly not increase the weight of.

Example three: CHENNU scholar, 25 years old, the frequent biped numbness of patient's readme was feared coldly, and intermittent attack with twinge, painfully sometimes can not be born.The frequent symptom of showing effect cold season obviously increases the weight of, the traditional Chinese medicine composition for treating of taking this kind took orally for treating Raynand's disease after course of treatment patient's attack times reduce, sx takes after two months that patient's biped does not have feeling of numbness, pain disappears, the foot temperature is normal.

Example four: from the Ms, 19 years old, the patient had Raynand's disease 3 years, turned cold gradually with weather at every turn, and patient's both hands refer to meet cold will losing color, and cyanosis is accompanied numb distending pain, and increases the weight of gradually, was difficult for alleviating, and took various Chinese-western medicine preparations, DeGrain.After take this kind took orally for treating Raynand's disease Chinese medicine composition after course of treatment, symptom is obviously alleviated, no feeling of numbness pain disappears, the ruddy body temperature of color is normal.Promptly fully recover three courses of treatment.

The specific embodiment

Example one: a kind of Chinese medicine composition of took orally for treating Raynand's disease, the crude drug of making active ingredient by following weight portion is: the Radix Astragali 20, Ramulus Cinnamomi 10, Radix Angelicae Sinensis 15, Radix Paeoniae Rubra 10, the Radix Paeoniae Alba 10, Rhizoma Chuanxiong 10, Radix Glycyrrhizae 10, Herba Asari 4, Semen Persicae 10, Fructus Evodiae 3, Rhizoma Atractylodis 10, Radix Aconiti Lateralis Preparata 10 and Rhizoma Zingiberis 11.

Claims

1. the Chinese medicine composition of a took orally for treating Raynand's disease, it is characterized in that crude drug and the weight portion thereof of making active ingredient are: the Radix Astragali 20, Ramulus Cinnamomi 10, Radix Angelicae Sinensis 15, Radix Paeoniae Rubra 10, the Radix Paeoniae Alba 10, Rhizoma Chuanxiong 10, Radix Glycyrrhizae 10, Herba Asari 4, Semen Persicae 10, Fructus Evodiae 3, Rhizoma Atractylodis 10, Radix Aconiti Lateralis Preparata 10 and Rhizoma Zingiberis 11.