CN101028503B - Oral Chinese-medicine composition for treating Raynaud's disease - Google Patents

Oral Chinese-medicine composition for treating Raynaud's disease Download PDF

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CN101028503B
CN101028503B CN2007100142356A CN200710014235A CN101028503B CN 101028503 B CN101028503 B CN 101028503B CN 2007100142356 A CN2007100142356 A CN 2007100142356A CN 200710014235 A CN200710014235 A CN 200710014235A CN 101028503 B CN101028503 B CN 101028503B
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disease
radix
cold
medicine composition
raynand
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CN101028503A (en
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贾卫滨
秦卫华
王芬
李永红
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Jia Weibin
Qin Weihua
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Abstract

An interior-applied Chinese medicine for treating Raynaud's disease is prepared from more than 13 Chinese-medicinal materials including cinnamon twig, astragalus root, Chinese angelica root, safflower, etc through decocting.

Description

A kind of Chinese medicine composition of took orally for treating Raynand's disease
Technical field
The present invention relates to a kind of Chinese medicine composition of took orally for treating Raynand's disease, belong to the field of Chinese medicines.
Background technology
After Raynand's disease is the cold or emotional distress of a kind of chance, cause that with strong contraction of paroxysmal acra small artery acro-ischemia is the disease of characteristics, claims the acra vasospastic disease again.Acra skin becomes livid purplely by pale during outbreak, then transfers flushing to.Raynaud at first described the color change phenomenon of this paroxysmal acra skin in 1862, thereby gained the name.Multiple reason all can cause this kind phenomenon, and what this phenomenon was secondary to other diseases is called Raynaud phenomenon or Raynaud syndrome, and no other reasons is called the Raynaud disease.
Primary disease belongs to the traditional Chinese medical science " deadly cold hand and foot " and categories such as " arthromyodynias "." concise exposition on febrile disease " as Cheng Wuji has more detailed description to this sick cause of disease, pathogenesis and clinical manifestation, think " the typhoid fever person of fainting, the how bright person of fainting, also cold, be far more than that cold limbs is also.Through day: the person of fainting, YIN QI and YANG QI circulating out of order is just for fainting.The person of fainting, the limbs with coldness is also, the meaning YANG QI falling into the interior, the contrary volt of steam, and brothers are also cold for it ".
The cause of disease of Raynaud disease it be unclear that so far; but cold, damage and medicine irritation are the reasons that causes the local vascular spasm; it also is key factor that the unusual or polypeptide of vasodilation lacks; the vasomotor nerve maincenter of oblongata is a former adjusting maincenter of skin, muscle vascular shrink tension; some zone of hypothalamus and cortex also is an important adjusting part; if these positions also can cause the generation of primary disease undermined.Because the neural characteristic distributions of peripheral vessels though promptly sympathetic nerve is the vasoconstrictor nerve fiber, is again the vasodilator nerve fiber in some zone, and hands and foot only have the vasoconstrictor nerve fiber, get involved so vasospasm disease is common in extremity.Except that above situation, the someone thinks the nervus centralis dysfunction, and sympathetic hyperfunction can cause primary disease.In addition, heredity, immune dysfunction and the arteriolar defective of congenital acra also can cause the Raynaud disease.
About pathogenesis two kinds of theories are arranged.The one,, Lewis can cause single finger Raynaud phenomenon outbreak with cold stimulation, and proposes the view that local defect makes blood vessel increase chill sensitive.The 2nd,, it is high partially with sympathetic activity that Raynaud thinks, and cause blood vessel to increase relevant to the blockage effect of normal stimulus.
The method of treatment Raynand's disease mainly contains at present:
The western modern medicine treatment of Raynand's disease: (1) naturopathy is used cold and heat succeed each other hydrotherapy, phototherapy, direct current electrotherapy and massotherapy; (2) Drug therapy medicament for expanding vascellum; (3) surgical intervention operative treatment.
The Chinese medicine of Raynand's disease: (1) internal treatment; (2) external treatment; (3) acupuncture treatment.
These methods have all played certain therapeutical effect on treating at present, have the surgery cost costliness, and are dangerous big, the low deficiency that waits of versatility.Domestic a large amount of utilization Chinese medicine is cured primary disease, and method is different, has obtained remarkable progress, but not ideal.
Summary of the invention
The objective of the invention is to overcome the deficiency of above-mentioned treatment Raynand's disease, and a kind of Chinese medicine composition of took orally for treating Raynand's disease is provided, it all selects natural Chinese medicinal herb for use, can fundamentally treat Raynand's disease.
Technical scheme of the present invention is: the Chinese medicine composition of this kind took orally for treating Raynand's disease, it is characterized in that, and make raw materials of effective components and be: Ramulus Cinnamomi 10 by stating weight portion, the Radix Astragali 15, Radix Angelicae Sinensis 10, the Radix Paeoniae Alba 10, Flos Carthami 10, Radix Glycyrrhizae 5, Caulis Akebiae 5, Rhizoma Chuanxiong 6, Rhizoma Atractylodis 10, Semen Persicae 10, Radix Clematidis 20, Radix Aconiti Lateralis Preparata 10 and Rhizoma Zingiberis 11.
During compounding pharmaceutical, the said medicine impurities in raw materials is removed, put into pot successively, add 500 ml waters, decoction gets final product half an hour, and is oral, sooner or later each potion.
Pharmacological action:
Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation.Control exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention etc.
The Radix Astragali: tonifying Qi and lifting yang, hemostasis by invigorating QI, the QI invigorating row stagnates, blood stasis removing eliminating stagnation, benefiting QI for strengthening the superficies, QI invigorating tonifying YIN, inducing diuresis to remove edema, warming the interior cold expelling, pus expelling by strengthening vital QI granulation promoting, strong body constitution, life lengthening.
Radix Angelicae Sinensis: benefiting blood and regulating blood circulation, menstruction regulating and pain relieving is moisturized laxation.
The Radix Paeoniae Alba: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Radix Glycyrrhizae: and middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.Control weakness of the spleen and stomach, lack of appetite, the stomachache loose stool, the overstrain heating, the consumptive lung disease cough, cardiopalmus is fainted from fear; Give birth to usefulness, control laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.
Flos Carthami: promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.Control amenorrhea, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
Caulis Akebiae: pathogenic fire purging row water.Promoting blood circulation.Control hot urination, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, sore throat pharyngalgia, inflexible pain all over, women's amenorrhea, galactostasis.
Rhizoma Chuanxiong: air to open is strongly fragrant, dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain.Control air-cooled headache, revolve dizzyly, the hypochondriac pain abdomen is painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.
Rhizoma Atractylodis: spleen invigorating, dampness, resolving depression, ward off dirty, expelling cold and relieving exterior syndrome.Control wet the Sheng and be stranded spleen, the asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting is had loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens flu, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.
Semen Persicae: blood stasis removing and clots absorbing, moisturize laxation.Control amenorrhea,, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.
Radix Clematidis: rheumatism, the meridian dredging, expectorant saliva, the hypochondriac lump of loosing.Control gout, insensitive impediment, chills and pain of the waist and kness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, the pharynx of all a fishbone or other bone caught in the throat.
Radix Aconiti Lateralis Preparata: recuperating depleted YANG is mended fire, dispelling cold and removing dampness.Control excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhea is fainted contrary, trusted subordinate's cold type of pain, the splenic diarrhea cold-dysentery, beriberi edema, children's's intermittent infantile convulsion, anemofrigid-damp arthralgia, contracture, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses.
Rhizoma Zingiberis: warming middle-JIAO is by cold, and recuperating depleted YANG is promoted blood circulation.Control trusted subordinate's cold type of pain, vomit and diarrhoea, the cold extremities faint pulse, cold fluid-retention is breathed with cough, anemofrigid-damp arthralgia, yang deficiency is told, hematochezia.
After the present invention mixed said medicine, its drug effect synergism in the Raynand's disease therapeutic process, had been obtained unexpected remarkable result.
Model case:
Example one: Cao, the woman, 27 years old, patient's readme the cold both hands colour of skin occurred meeting and loses color before 3 years, and then cyanosis continues, flushing, recover normal after chance is warm gradually, simultaneously with numb distending pain, autumn and winter season shows effect frequently. and one week of traditional Chinese medicine composition for treating back patient's paresthesia epilepsy number of times of taking this kind took orally for treating Raynand's disease reduces, numb distending pain is sent out cold and is alleviated.The both hands feeling of numbness disappears after January, and color is more ruddy, still has fear of cold. and strengthen living nursing, regulate diet.Patient's both hands do not have feeling of numbness after March, and the skin temperature is normal, and color is ruddy, meet coldly not increase the weight of.Follow up a case by regular visits to and do not see recurrence in 2 years.
Example two: the summer so-and-so, the woman,, 23 years old age.The patient fell ill before 3 years to both hands wrist place, when the state of an illness is the most serious, soaked with the warm water, still needed 2 many hours ability to alleviate.Be Raynaud disease on inspection.Begin to take the Chinese medicine composition of this kind took orally for treating Raynand's disease the year before.After medication course of treatment obviously sensation take a turn for the better, promptly accuse recovery from illness after three courses of treatment, for after treatment continues course of treatment of medication again.
Example three: Pueraria lobota so-and-so, the man, 25 years old, the frequent biped numbness of patient's readme was feared coldly, intermittent attack with twinge, painfully sometimes can not be born.Through taking the traditional Chinese medicine composition for treating of this kind took orally for treating Raynand's disease, recovery from illness in 45 days.
Example four: Zhang, the woman, 49 years old, the patient had Raynand's disease 5 years, recently because of weather turns cold gradually, patient's both hands refer to meet cold losing color, and cyanosis is accompanied numb distending pain, increase the weight of gradually, be difficult for to alleviate, take the Chinese medicine composition of this kind took orally for treating Raynand's disease after, promptly fully recover three courses of treatment.
The specific embodiment
Example one: a kind of Chinese medicine composition of took orally for treating Raynand's disease, make raw materials of effective components and be: Ramulus Cinnamomi 10, the Radix Astragali 15, Radix Angelicae Sinensis 10, the Radix Paeoniae Alba 10 by stating weight portion, Flos Carthami 10, Radix Glycyrrhizae 5, Caulis Akebiae 5, Rhizoma Chuanxiong 6, Rhizoma Atractylodis 10, Semen Persicae 10, Radix Clematidis 20, Radix Aconiti Lateralis Preparata 10, Rhizoma Zingiberis 11.
During compounding pharmaceutical, the said medicine impurities in raw materials is removed, put into pot successively, add 500 ml waters, decoction gets final product half an hour, and is oral, sooner or later each potion.

Claims (1)

1. the Chinese medicine composition of a took orally for treating Raynand's disease is characterized in that, makes raw materials of effective components by following weight portion to be: Ramulus Cinnamomi 10, the Radix Astragali 15, Radix Angelicae Sinensis 10, the Radix Paeoniae Alba 10, Flos Carthami 10, Radix Glycyrrhizae 5, Caulis Akebiae 5, Rhizoma Chuanxiong 6, Rhizoma Atractylodis 10, Semen Persicae 10, Radix Clematidis 20, Radix Aconiti Lateralis Preparata 10, Rhizoma Zingiberis 11.
CN2007100142356A 2007-04-05 2007-04-05 Oral Chinese-medicine composition for treating Raynaud's disease Expired - Fee Related CN101028503B (en)

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CN103212049A (en) * 2013-04-28 2013-07-24 长治市郊区黄碾镇中心卫生院 Medicament for treating Raynaud syndrome
CN105535878A (en) * 2014-11-03 2016-05-04 陈琼芳 Compound medicine for treating Raynaud's syndrome

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1106674A (en) * 1994-10-13 1995-08-16 汪志伟 Traditional Chinese medicine for curing paralysis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1106674A (en) * 1994-10-13 1995-08-16 汪志伟 Traditional Chinese medicine for curing paralysis

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
江红
江红;薛雷.温通法治疗雷诺氏病20例.辽宁中医学院学报4卷 4期.2002,4卷(4期),283页. *
薛雷.温通法治疗雷诺氏病20例.辽宁中医学院学报4卷 4期.2002,4卷(4期),283页.
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