CN102227503B - 重组载体 - Google Patents

重组载体 Download PDF

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Publication number
CN102227503B
CN102227503B CN200980147515.1A CN200980147515A CN102227503B CN 102227503 B CN102227503 B CN 102227503B CN 200980147515 A CN200980147515 A CN 200980147515A CN 102227503 B CN102227503 B CN 102227503B
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sequence
retrovirus
seq
cells
vector
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Expired - Fee Related
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CN200980147515.1A
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Chinese (zh)
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CN102227503A (zh
Inventor
哈利·E·格鲁贝尔
道格拉斯·乔利
奥马尔·佩雷斯
克里斯托弗·R·洛格
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Suoyuan Biomedical Usa Co ltd
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Tocagen Inc
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C12Y305/04—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amidines (3.5.4)
    • C12Y305/04001—Cytosine deaminase (3.5.4.1)
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/10—Vectors comprising a special translation-regulating system regulates levels of translation
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

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  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200980147515.1A 2008-09-26 2009-09-26 重组载体 Expired - Fee Related CN102227503B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510624987.9A CN105624193B (zh) 2008-09-26 2009-09-26 重组载体

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US10066608P 2008-09-26 2008-09-26
US61/100,666 2008-09-26
US12061808P 2008-12-08 2008-12-08
US61/120,618 2008-12-08
US18682309P 2009-06-13 2009-06-13
US61/186,823 2009-06-13
PCT/US2009/058512 WO2010036986A2 (en) 2008-09-26 2009-09-26 Recombinant vectors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201510624987.9A Division CN105624193B (zh) 2008-09-26 2009-09-26 重组载体

Publications (2)

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CN102227503A CN102227503A (zh) 2011-10-26
CN102227503B true CN102227503B (zh) 2015-10-21

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ID=42060421

Family Applications (4)

Application Number Title Priority Date Filing Date
CN200980147515.1A Expired - Fee Related CN102227503B (zh) 2008-09-26 2009-09-26 重组载体
CN201510624987.9A Expired - Fee Related CN105624193B (zh) 2008-09-26 2009-09-26 重组载体
CN200980147509.6A Expired - Fee Related CN102227501B (zh) 2008-09-26 2009-09-26 基因治疗载体和胞嘧啶脱氨酶
CN201510505943.4A Pending CN105274125A (zh) 2008-09-26 2009-09-26 基因治疗载体和胞嘧啶脱氨酶

Family Applications After (3)

Application Number Title Priority Date Filing Date
CN201510624987.9A Expired - Fee Related CN105624193B (zh) 2008-09-26 2009-09-26 重组载体
CN200980147509.6A Expired - Fee Related CN102227501B (zh) 2008-09-26 2009-09-26 基因治疗载体和胞嘧啶脱氨酶
CN201510505943.4A Pending CN105274125A (zh) 2008-09-26 2009-09-26 基因治疗载体和胞嘧啶脱氨酶

Country Status (18)

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US (3) US8722867B2 (enExample)
EP (4) EP3502256A3 (enExample)
JP (6) JP5771147B2 (enExample)
KR (3) KR101724162B1 (enExample)
CN (4) CN102227503B (enExample)
AU (1) AU2009303690B2 (enExample)
BR (1) BRPI0919113A2 (enExample)
CA (1) CA2738472A1 (enExample)
CO (1) CO6362050A2 (enExample)
DK (1) DK2346995T3 (enExample)
EA (2) EA027693B1 (enExample)
ES (2) ES2709481T3 (enExample)
IL (3) IL211847A (enExample)
MX (3) MX2011003039A (enExample)
MY (1) MY156333A (enExample)
NZ (1) NZ592070A (enExample)
WO (2) WO2010036986A2 (enExample)
ZA (1) ZA201102115B (enExample)

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