CN102215839B - 用于人工喂养重病的重症特护患者的脂肪乳剂 - Google Patents

用于人工喂养重病的重症特护患者的脂肪乳剂 Download PDF

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Publication number
CN102215839B
CN102215839B CN200980145702.6A CN200980145702A CN102215839B CN 102215839 B CN102215839 B CN 102215839B CN 200980145702 A CN200980145702 A CN 200980145702A CN 102215839 B CN102215839 B CN 102215839B
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China
Prior art keywords
acid
triglycerides
application
fat emulsion
fatty acids
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
CN200980145702.6A
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English (en)
Chinese (zh)
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CN102215839A (zh
Inventor
迈克尔·博尔
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B Braun Melsungen AG
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B Braun Melsungen AG
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0029Parenteral nutrition; Parenteral nutrition compositions as drug carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Dispersion Chemistry (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Food Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN200980145702.6A 2008-11-18 2009-11-09 用于人工喂养重病的重症特护患者的脂肪乳剂 Ceased CN102215839B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008057867.3 2008-11-18
DE102008057867A DE102008057867A1 (de) 2008-11-18 2008-11-18 Fettemulsion zur künstlichen Ernährung von schwerkranken Intensivpatienten
PCT/EP2009/064839 WO2010057804A1 (de) 2008-11-18 2009-11-09 Fettemulsion zur künstlichen ernährung von schwerkranken intensivpatienten

Publications (2)

Publication Number Publication Date
CN102215839A CN102215839A (zh) 2011-10-12
CN102215839B true CN102215839B (zh) 2016-08-24

Family

ID=41581163

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980145702.6A Ceased CN102215839B (zh) 2008-11-18 2009-11-09 用于人工喂养重病的重症特护患者的脂肪乳剂

Country Status (12)

Country Link
US (2) US20110207819A1 (enExample)
EP (1) EP2355813B1 (enExample)
JP (1) JP2012509292A (enExample)
KR (1) KR20110084513A (enExample)
CN (1) CN102215839B (enExample)
BR (1) BRPI0921917B8 (enExample)
CA (1) CA2739390C (enExample)
DE (1) DE102008057867A1 (enExample)
ES (1) ES2561207T3 (enExample)
MX (1) MX338223B (enExample)
RU (1) RU2528108C2 (enExample)
WO (1) WO2010057804A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009013914B4 (de) * 2009-03-19 2011-05-05 Bruker Daltonik Gmbh Kalibriersubstanzen für Atmosphärendruck-Ionenquellen
KR20130093180A (ko) * 2011-01-31 2013-08-21 니폰 조키 세야쿠 가부시키가이샤 항암제에 의한 말초신경장애의 예방 또는 치료제
US8183227B1 (en) 2011-07-07 2012-05-22 Chemo S. A. France Compositions, kits and methods for nutrition supplementation
US8168611B1 (en) 2011-09-29 2012-05-01 Chemo S.A. France Compositions, kits and methods for nutrition supplementation
CN106900888B (zh) * 2015-12-23 2021-12-24 丰益(上海)生物技术研发中心有限公司 含有奇数碳脂肪酸结构脂的油脂组合物及其应用
TWI749016B (zh) * 2016-06-08 2021-12-11 董宇紅 具有奇數碳的脂類化合物及其作為醫藥組合物或者營養補充劑的用途
CN109602704A (zh) * 2019-01-23 2019-04-12 广东嘉博制药有限公司 丁酸氯维地平脂肪乳注射液及其制备工艺
CN110326789A (zh) * 2019-06-11 2019-10-15 上海互众药业有限公司 一种脂肪乳食品补充液及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030162833A1 (en) * 2001-08-01 2003-08-28 Roe Charles R. Fatty acid treatment for cardiac patients
US6740679B1 (en) * 1999-02-05 2004-05-25 Baylor University Medical Center Nutritional supplement or pharmaceutical preparation comprising triglycerides with seven-carbon fatty acid
WO2004103307A2 (en) * 2003-05-20 2004-12-02 Baylor Research Institute Method of use of five and fifteen carbon fatty acids

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2515174A1 (fr) 1981-10-23 1983-04-29 Roussel Uclaf Nouveaux triglycerides, procede de preparation et d'applications en dietetique et en therapeutique
US4526902A (en) 1983-10-24 1985-07-02 Century Laboratories, Inc. Combined fatty acid composition for treatment or prophylaxis of thrombo-embolic conditions
DE3721137A1 (de) 1987-06-26 1989-01-05 Dietl Hans Fettemulsion zur intravenoesen anwendung
DE3722540A1 (de) 1987-07-08 1989-01-19 Fresenius Ag Fettemulsion, verfahren zu ihrer herstellung und ihre verwendung
DE3734147C2 (de) * 1987-10-09 1998-10-29 Braun Melsungen Ag Isotone omega-3-fettsäurenhaltige Fettemulsion und ihre Verwendung
AU682894B2 (en) * 1993-10-28 1997-10-23 Institut National De La Recherche Agronomique Composition based on amino acids intended for the treatment of sepsis or of an attack bringing about an inflammatory reaction, in animals and man
RU2155612C2 (ru) * 1997-01-30 2000-09-10 Скрипченко Наталия Викторовна Способ лечения острых инфекционных заболеваний периферической нервной системы
NZ513329A (en) * 1999-02-05 2003-11-28 Baylor University Medical Ct Nutritional supplement or pharmaceutical preparation comprising triglycerides with seven-carbon fatty acid
DK1434597T3 (da) * 2001-10-11 2012-02-27 Merck Serono Sa Anvendelse af gp130-aktivatorer ved diabetisk neuropati
CA2573054C (en) * 2004-07-02 2012-10-09 Baylor Research Institute Glycogen or polysaccharide storage disease treatment method
ATE358468T1 (de) * 2005-02-16 2007-04-15 Straetmans Chemische Produktio Kosmetische und dermatologische lichtschutzformulierungen mit einem gehalt an chemischen uv-filtern und triheptanonin
KR20150038525A (ko) 2006-09-26 2015-04-08 베일러 리서치 인스티튜트 영양물 센서

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6740679B1 (en) * 1999-02-05 2004-05-25 Baylor University Medical Center Nutritional supplement or pharmaceutical preparation comprising triglycerides with seven-carbon fatty acid
US20030162833A1 (en) * 2001-08-01 2003-08-28 Roe Charles R. Fatty acid treatment for cardiac patients
WO2004103307A2 (en) * 2003-05-20 2004-12-02 Baylor Research Institute Method of use of five and fifteen carbon fatty acids

Also Published As

Publication number Publication date
RU2528108C2 (ru) 2014-09-10
JP2012509292A (ja) 2012-04-19
WO2010057804A1 (de) 2010-05-27
MX2011005201A (es) 2011-06-01
CA2739390A1 (en) 2010-05-27
MX338223B (es) 2016-04-08
CN102215839A (zh) 2011-10-12
EP2355813A1 (de) 2011-08-17
US20110207819A1 (en) 2011-08-25
ES2561207T3 (es) 2016-02-25
EP2355813B1 (de) 2015-11-04
BRPI0921917B8 (pt) 2021-05-25
KR20110084513A (ko) 2011-07-25
BRPI0921917B1 (pt) 2020-08-25
RU2011124887A (ru) 2012-12-27
DE102008057867A1 (de) 2010-05-20
US20160051506A1 (en) 2016-02-25
BRPI0921917A2 (pt) 2015-12-29
CA2739390C (en) 2016-05-03

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Decision date of declaring invalidation: 20181205

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