CN102202668A - 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品 - Google Patents

磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品 Download PDF

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CN102202668A
CN102202668A CN2009801431736A CN200980143173A CN102202668A CN 102202668 A CN102202668 A CN 102202668A CN 2009801431736 A CN2009801431736 A CN 2009801431736A CN 200980143173 A CN200980143173 A CN 200980143173A CN 102202668 A CN102202668 A CN 102202668A
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mtor
hydrogen
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C·加西亚-埃切夫埃里亚
S-M·马伊拉
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Novartis AG
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Novartis AG
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    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
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CN2009801431736A 2008-10-31 2009-10-29 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品 Pending CN102202668A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510402018.9A CN105030784A (zh) 2008-10-31 2009-10-29 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08168044 2008-10-31
EP08168044.9 2008-10-31
PCT/EP2009/064274 WO2010049481A1 (en) 2008-10-31 2009-10-29 Combination of a phosphatidylinositol-3-kinase (pi3k) inhibitor and a mtor inhibitor

Related Child Applications (1)

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CN201510402018.9A Division CN105030784A (zh) 2008-10-31 2009-10-29 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品

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CN102202668A true CN102202668A (zh) 2011-09-28

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CN2009801431736A Pending CN102202668A (zh) 2008-10-31 2009-10-29 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品
CN201510402018.9A Pending CN105030784A (zh) 2008-10-31 2009-10-29 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品

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US (3) US20110195966A1 (https=)
EP (1) EP2349275B1 (https=)
JP (4) JP2012506898A (https=)
KR (1) KR20110090911A (https=)
CN (2) CN102202668A (https=)
AU (1) AU2009309616B2 (https=)
BR (1) BRPI0921802A8 (https=)
CA (1) CA2736361C (https=)
ES (1) ES2627677T3 (https=)
MX (1) MX2011004585A (https=)
RU (2) RU2538683C2 (https=)
WO (1) WO2010049481A1 (https=)

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EP2968281B1 (en) 2013-03-13 2020-08-05 The Board of Regents of The University of Texas System Mtor inhibitors for prevention of intestinal polyp growth
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KR20150127720A (ko) 2013-03-14 2015-11-17 유니버시티 오브 매릴랜드, 발티모어 안드로겐 수용체 하향 조절제 및 그의 용도
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CN110114070A (zh) 2016-11-23 2019-08-09 诺华公司 使用依维莫司(everolimus)、达托里昔布(dactolisib)或二者增强免疫反应的方法
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CN112294967A (zh) * 2020-09-30 2021-02-02 四川大学 一种mTOR抑制剂与抗癌药物的用途

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Publication number Priority date Publication date Assignee Title
CN103483345A (zh) * 2013-09-25 2014-01-01 中山大学 Pi3k 激酶抑制剂、包含其的药物组合物及其应用
CN103483345B (zh) * 2013-09-25 2016-07-06 中山大学 Pi3k激酶抑制剂、包含其的药物组合物及其应用

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CA2736361C (en) 2017-10-10
ES2627677T3 (es) 2017-07-31
JP2012506898A (ja) 2012-03-22
RU2011121508A (ru) 2012-12-10
CN105030784A (zh) 2015-11-11
JP2015013883A (ja) 2015-01-22
CA2736361A1 (en) 2010-05-06
KR20110090911A (ko) 2011-08-10
BRPI0921802A2 (pt) 2016-09-27
BRPI0921802A8 (pt) 2018-03-13
JP2017002058A (ja) 2017-01-05
AU2009309616B2 (en) 2014-02-13
EP2349275B1 (en) 2017-03-08
RU2014115188A (ru) 2015-10-20
US20160136175A1 (en) 2016-05-19
MX2011004585A (es) 2011-06-01
JP2018197243A (ja) 2018-12-13
WO2010049481A1 (en) 2010-05-06
US20110195966A1 (en) 2011-08-11
RU2538683C2 (ru) 2015-01-10
US20180133226A1 (en) 2018-05-17
EP2349275A1 (en) 2011-08-03
AU2009309616A1 (en) 2010-05-06
AU2009309616A2 (en) 2011-07-07

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