CN102177255B - 利用foxo3a的多态性和单元型预测和促进健康衰老和长寿的方法 - Google Patents

利用foxo3a的多态性和单元型预测和促进健康衰老和长寿的方法 Download PDF

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CN102177255B
CN102177255B CN200980140170.7A CN200980140170A CN102177255B CN 102177255 B CN102177255 B CN 102177255B CN 200980140170 A CN200980140170 A CN 200980140170A CN 102177255 B CN102177255 B CN 102177255B
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allele
foxo3a
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polymorphism
gene
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CN102177255A (zh
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蒂莫斯·艾奇逊·唐隆
布拉德利·约翰·威尔科克斯
戴维·J·库尔巴
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KUAKINI MEDICAL CT
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • G01—MEASURING; TESTING
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
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    • C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
    • C12Q2535/125—Allele specific primer extension
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN200980140170.7A 2008-08-10 2009-08-10 利用foxo3a的多态性和单元型预测和促进健康衰老和长寿的方法 Active CN102177255B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8772208P 2008-08-10 2008-08-10
US61/087,722 2008-08-10
PCT/US2009/053307 WO2010019519A2 (en) 2008-08-10 2009-08-10 Method of using foxo3a polymorphisms and haplotypes to predict and promote healthy aging and longevity

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CN102177255A CN102177255A (zh) 2011-09-07
CN102177255B true CN102177255B (zh) 2015-12-16

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US (3) US20110212447A1 (https=)
EP (1) EP2324127B1 (https=)
JP (1) JP5814119B2 (https=)
KR (2) KR101649541B1 (https=)
CN (1) CN102177255B (https=)
AU (1) AU2009282172B2 (https=)
CA (1) CA2733597C (https=)
DK (1) DK2324127T3 (https=)
WO (1) WO2010019519A2 (https=)

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US20110212447A1 (en) * 2008-08-10 2011-09-01 Timothy Atchison Donlon Method of Using FOXO3A Polymorphisms and Haplotypes to Predict and Promote Healthy Aging and Longevity
US8990135B2 (en) * 2010-06-15 2015-03-24 The Regents Of The University Of Michigan Personalized health risk assessment for critical care
CN103233001B (zh) * 2012-06-25 2016-11-02 西北农林科技大学 秦川牛FoxO1基因单核苷酸多态性分子标记的检测方法与应用
KR102017562B1 (ko) * 2013-03-13 2019-09-03 (주)아모레퍼시픽 미백 효능 물질의 스크리닝 방법
WO2017062751A1 (en) * 2015-10-08 2017-04-13 The Regents Of The University Of California Compounds and methods for promoting stress resistance
WO2018183353A1 (en) * 2017-03-27 2018-10-04 Cardax Pharma, Inc. Small molecule compounds to support healthy human aging
WO2018209222A1 (en) * 2017-05-12 2018-11-15 Massachusetts Institute Of Technology Systems and methods for crowdsourcing, analyzing, and/or matching personal data
WO2019156591A1 (en) * 2018-02-12 2019-08-15 Limited Liability Company "Gero" Methods and systems for prediction of frailty background
CN111235250A (zh) * 2020-03-31 2020-06-05 中国科学院昆明动物研究所 与健康老龄相关的关键通路及其外周血dna甲基化位点标志物和应用
CN115466321B (zh) * 2022-09-23 2024-03-22 南方医科大学珠江医院 FOXO3a-DRI肽段、其药物组合物及应用

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WO2010019519A3 (en) 2010-05-27
AU2009282172B2 (en) 2016-06-02
JP5814119B2 (ja) 2015-11-17
EP2324127B1 (en) 2015-01-21
CA2733597A1 (en) 2010-02-18
AU2009282172A1 (en) 2010-02-18
CN102177255A (zh) 2011-09-07
KR20160102081A (ko) 2016-08-26
JP2011530312A (ja) 2011-12-22
US20110212447A1 (en) 2011-09-01
HK1158271A1 (en) 2012-07-13
KR20110057147A (ko) 2011-05-31
DK2324127T3 (en) 2015-04-27
US20150337383A1 (en) 2015-11-26
US20130295566A1 (en) 2013-11-07
EP2324127A2 (en) 2011-05-25
CA2733597C (en) 2019-02-26
US12534761B2 (en) 2026-01-27
WO2010019519A2 (en) 2010-02-18
KR101649541B1 (ko) 2016-08-19
EP2324127A4 (en) 2012-06-13

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