CN1021632C - 制备含有有机锌螯合物的药用组合物的方法 - Google Patents

制备含有有机锌螯合物的药用组合物的方法 Download PDF

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Publication number
CN1021632C
CN1021632C CN87102747A CN87102747A CN1021632C CN 1021632 C CN1021632 C CN 1021632C CN 87102747 A CN87102747 A CN 87102747A CN 87102747 A CN87102747 A CN 87102747A CN 1021632 C CN1021632 C CN 1021632C
Authority
CN
China
Prior art keywords
iodo
chloro
hydroxyquinoline
zinc
chelate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN87102747A
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English (en)
Chinese (zh)
Other versions
CN87102747A (zh
Inventor
吉尤拉·西贝斯蒂恩
伊斯特万·西门尼
吉泽拉·米赫利克斯
马尔他·科娃克斯
弗利格耶斯·格尔格尼
马顿·菲克特
帕尔·瓦格
伊斯特万·塞尔斯
亚诺斯·埃格利
马尔利亚·斯泽利
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egis Gyógyszergyár Zrt
Original Assignee
Egis Gyógyszergyár Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egis Gyógyszergyár Zrt filed Critical Egis Gyógyszergyár Zrt
Publication of CN87102747A publication Critical patent/CN87102747A/zh
Application granted granted Critical
Publication of CN1021632C publication Critical patent/CN1021632C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/30—Metal salts; Chelates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN87102747A 1986-04-18 1987-04-14 制备含有有机锌螯合物的药用组合物的方法 Expired - Fee Related CN1021632C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU861623A HU196554B (en) 1986-04-18 1986-04-18 Process for production of medical compounds with fungicidal effect
HU1623/86 1986-04-18

Publications (2)

Publication Number Publication Date
CN87102747A CN87102747A (zh) 1987-12-09
CN1021632C true CN1021632C (zh) 1993-07-21

Family

ID=10955373

Family Applications (1)

Application Number Title Priority Date Filing Date
CN87102747A Expired - Fee Related CN1021632C (zh) 1986-04-18 1987-04-14 制备含有有机锌螯合物的药用组合物的方法

Country Status (24)

Country Link
US (2) US4868172A (enExample)
JP (1) JPS62294616A (enExample)
KR (1) KR870010036A (enExample)
CN (1) CN1021632C (enExample)
AU (1) AU601725B2 (enExample)
BE (1) BE1001251A4 (enExample)
BG (1) BG47945A3 (enExample)
CA (1) CA1306685C (enExample)
CH (1) CH671880A5 (enExample)
CS (1) CS269993B2 (enExample)
DE (1) DE3713372A1 (enExample)
DK (1) DK200087A (enExample)
ES (1) ES2005165A6 (enExample)
FI (1) FI871703A7 (enExample)
FR (1) FR2597343B1 (enExample)
GB (1) GB2189144B (enExample)
GR (1) GR870617B (enExample)
HU (1) HU196554B (enExample)
IL (1) IL82238A0 (enExample)
IT (1) IT1207583B (enExample)
NL (1) NL8700906A (enExample)
PL (1) PL265249A1 (enExample)
SE (1) SE8701592L (enExample)
YU (1) YU46313B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0355383A1 (de) * 1988-07-28 1990-02-28 Ciba-Geigy Ag Solubilisierungsverfahren
WO1990015603A1 (en) * 1989-06-12 1990-12-27 Shiseido Company, Ltd. Antipruritic composition
US5219847A (en) * 1989-06-12 1993-06-15 Shiseido Company, Ltd. Antipruritic composition
US7846919B2 (en) * 1998-02-10 2010-12-07 Dermex Pharmaceuticals, Llc Chelated 8-hydroxyquinoline and use thereof in a method of treating epithelial lesions
US9089730B2 (en) * 2010-11-25 2015-07-28 Zzakey Technologies Ltd Biodegradable fire-fighting formulation
CN111937886A (zh) * 2019-05-16 2020-11-17 兰州大学 一种8-羟基喹啉配合物的制备及其在防治植物病害中的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH494760A (de) * 1962-11-30 1970-08-15 Metalsalts Corp Verfahren zur Herstellung von Metall-8-chinolinolaten mit Ausnahme der Alkalimetallderivate
US3886277A (en) * 1967-02-14 1975-05-27 Schwarzkopf Gmbh Hans Methods of controlling dandruff using 5,7-dichloro-8-hydroxy quinoline
BE755584A (fr) * 1969-09-19 1971-03-01 Ugine Kuhlmann Nouveaux medicaments a activite amoebicide
DE2154020A1 (de) * 1971-10-29 1973-05-03 Hoechst Ag Metallkomplexe von substituierten benzimidazolen
NO156672C (no) * 1975-10-24 1987-11-04 Chapman Chem Co Preparat med antimikrobiell og eventuelt insekticid virkning og anvendelse av et slikt preparat som tre- og vekstbeskyttelsesmiddel.
ZA786259B (en) * 1977-11-09 1979-10-31 Procter & Gamble Therapeutic composition
DE3129685C2 (de) * 1981-07-28 1986-11-06 geb. Stoffel Annemarie Dr. 7802 Merzhausen Buck Antiseptische Lösung

Also Published As

Publication number Publication date
NL8700906A (nl) 1987-11-16
PL265249A1 (en) 1988-07-21
DK200087A (da) 1987-10-19
GB2189144A (en) 1987-10-21
BG47945A3 (bg) 1990-10-15
DE3713372C2 (enExample) 1991-12-19
IL82238A0 (en) 1987-10-30
KR870010036A (ko) 1987-11-30
YU69387A (en) 1988-12-31
FR2597343A1 (fr) 1987-10-23
BE1001251A4 (fr) 1989-09-05
CN87102747A (zh) 1987-12-09
FI871703A0 (fi) 1987-04-16
CH671880A5 (enExample) 1989-10-13
IT8720168A0 (it) 1987-04-17
AU601725B2 (en) 1990-09-20
DK200087D0 (da) 1987-04-15
HU196554B (en) 1988-12-28
AU7175887A (en) 1987-10-22
US4871728A (en) 1989-10-03
SE8701592L (sv) 1987-10-19
HUT43781A (en) 1987-12-28
CA1306685C (en) 1992-08-25
CS269993B2 (en) 1990-05-14
GB8709166D0 (en) 1987-05-20
YU46313B (sh) 1993-05-28
IT1207583B (it) 1989-05-25
GR870617B (en) 1987-08-18
JPS62294616A (ja) 1987-12-22
GB2189144B (en) 1990-04-25
JPH0525858B2 (enExample) 1993-04-14
FI871703A7 (fi) 1987-10-19
CS203587A2 (en) 1989-04-14
DE3713372A1 (de) 1987-10-22
ES2005165A6 (es) 1989-03-01
SE8701592D0 (sv) 1987-04-16
FR2597343B1 (fr) 1991-11-29
US4868172A (en) 1989-09-19

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