ES2005165A6 - Procedimiento de preparacion del complejo de cincl de 5-cloro-7-yodo-8-hidroxi-quinolina - Google Patents

Procedimiento de preparacion del complejo de cincl de 5-cloro-7-yodo-8-hidroxi-quinolina

Info

Publication number
ES2005165A6
ES2005165A6 ES8701110A ES8701110A ES2005165A6 ES 2005165 A6 ES2005165 A6 ES 2005165A6 ES 8701110 A ES8701110 A ES 8701110A ES 8701110 A ES8701110 A ES 8701110A ES 2005165 A6 ES2005165 A6 ES 2005165A6
Authority
ES
Spain
Prior art keywords
pharmaceutical composition
complex
zinc complex
formula
organic zinc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8701110A
Other languages
English (en)
Inventor
Gyula Sebestyen
Istvan Simony
Gizella Miholics
Marta Kovacs
Frigyes Gorgenyi
Marton Fekete
Pal Vago
Istvan Seres
Janos Egri
Maria Szeli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ES2005165A6 publication Critical patent/ES2005165A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/30—Metal salts; Chelates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Abstract

EL COMPLEJO DE FORMULA (I) SE PREPARA HACIENDO REACCIONAR UNA SOLUCION DE UNA SAL METALICA ALCALINA DE 5-CLORO-7-YODO-8-HIDROXI-QUINOLINA CON UNA SOLUCION QUE CONTENGA UN EXCESO DE UNA SAL INORGANICA U ORGANICA DE CINC O UN COMPLEJO DE CINC DOTADO DE UNA CONSTANTE DE ESTABILIDAD INFERIOR A LA DEL COMPLEJO DE FORMULA (I), Y SEPARANDO EL PRODUCTO PRECIPITADO.LOS PRODUCTOS OBTENIDOS SON APLICABLES AL TRATAMIENTO EFECTIVO DE INFECCIONES MICOTICAS EN LA SUPERFICIE DE LA PIEL, MEMBRANAS, MUCOSAS O UÑAS.
ES8701110A 1986-04-18 1987-04-15 Procedimiento de preparacion del complejo de cincl de 5-cloro-7-yodo-8-hidroxi-quinolina Expired ES2005165A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU861623A HU196554B (en) 1986-04-18 1986-04-18 Process for production of medical compounds with fungicidal effect

Publications (1)

Publication Number Publication Date
ES2005165A6 true ES2005165A6 (es) 1989-03-01

Family

ID=10955373

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8701110A Expired ES2005165A6 (es) 1986-04-18 1987-04-15 Procedimiento de preparacion del complejo de cincl de 5-cloro-7-yodo-8-hidroxi-quinolina

Country Status (24)

Country Link
US (2) US4868172A (es)
JP (1) JPS62294616A (es)
KR (1) KR870010036A (es)
CN (1) CN1021632C (es)
AU (1) AU601725B2 (es)
BE (1) BE1001251A4 (es)
BG (1) BG47945A3 (es)
CA (1) CA1306685C (es)
CH (1) CH671880A5 (es)
CS (1) CS269993B2 (es)
DE (1) DE3713372A1 (es)
DK (1) DK200087A (es)
ES (1) ES2005165A6 (es)
FI (1) FI871703A (es)
FR (1) FR2597343B1 (es)
GB (1) GB2189144B (es)
GR (1) GR870617B (es)
HU (1) HU196554B (es)
IL (1) IL82238A0 (es)
IT (1) IT1207583B (es)
NL (1) NL8700906A (es)
PL (1) PL265249A1 (es)
SE (1) SE8701592L (es)
YU (1) YU46313B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0355383A1 (de) * 1988-07-28 1990-02-28 Ciba-Geigy Ag Solubilisierungsverfahren
WO1990015603A1 (fr) * 1989-06-12 1990-12-27 Shiseido Company, Ltd. Composition antipruritique
US5219847A (en) * 1989-06-12 1993-06-15 Shiseido Company, Ltd. Antipruritic composition
US7846919B2 (en) * 1998-02-10 2010-12-07 Dermex Pharmaceuticals, Llc Chelated 8-hydroxyquinoline and use thereof in a method of treating epithelial lesions
US9089730B2 (en) * 2010-11-25 2015-07-28 Zzakey Technologies Ltd Biodegradable fire-fighting formulation
CN111937886A (zh) * 2019-05-16 2020-11-17 兰州大学 一种8-羟基喹啉配合物的制备及其在防治植物病害中的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH494760A (de) * 1962-11-30 1970-08-15 Metalsalts Corp Verfahren zur Herstellung von Metall-8-chinolinolaten mit Ausnahme der Alkalimetallderivate
US3886277A (en) * 1967-02-14 1975-05-27 Schwarzkopf Gmbh Hans Methods of controlling dandruff using 5,7-dichloro-8-hydroxy quinoline
BE755584A (fr) * 1969-09-19 1971-03-01 Ugine Kuhlmann Nouveaux medicaments a activite amoebicide
DE2154020A1 (de) * 1971-10-29 1973-05-03 Hoechst Ag Metallkomplexe von substituierten benzimidazolen
NO156672C (no) * 1975-10-24 1987-11-04 Chapman Chem Co Preparat med antimikrobiell og eventuelt insekticid virkning og anvendelse av et slikt preparat som tre- og vekstbeskyttelsesmiddel.
ZA786259B (en) * 1977-11-09 1979-10-31 Procter & Gamble Therapeutic composition
DE3129685C2 (de) * 1981-07-28 1986-11-06 geb. Stoffel Annemarie Dr. 7802 Merzhausen Buck Antiseptische Lösung

Also Published As

Publication number Publication date
US4871728A (en) 1989-10-03
DK200087D0 (da) 1987-04-15
GB8709166D0 (en) 1987-05-20
GB2189144B (en) 1990-04-25
HUT43781A (en) 1987-12-28
AU7175887A (en) 1987-10-22
HU196554B (en) 1988-12-28
GR870617B (en) 1987-08-18
DE3713372C2 (es) 1991-12-19
CN87102747A (zh) 1987-12-09
BG47945A3 (en) 1990-10-15
GB2189144A (en) 1987-10-21
JPH0525858B2 (es) 1993-04-14
KR870010036A (ko) 1987-11-30
CN1021632C (zh) 1993-07-21
AU601725B2 (en) 1990-09-20
CS203587A2 (en) 1989-04-14
SE8701592D0 (sv) 1987-04-16
NL8700906A (nl) 1987-11-16
SE8701592L (sv) 1987-10-19
DK200087A (da) 1987-10-19
CS269993B2 (en) 1990-05-14
FR2597343A1 (fr) 1987-10-23
PL265249A1 (en) 1988-07-21
IL82238A0 (en) 1987-10-30
FI871703A0 (fi) 1987-04-16
BE1001251A4 (fr) 1989-09-05
US4868172A (en) 1989-09-19
JPS62294616A (ja) 1987-12-22
YU46313B (sh) 1993-05-28
CA1306685C (en) 1992-08-25
IT1207583B (it) 1989-05-25
FI871703A (fi) 1987-10-19
FR2597343B1 (fr) 1991-11-29
IT8720168A0 (it) 1987-04-17
DE3713372A1 (de) 1987-10-22
YU69387A (en) 1988-12-31
CH671880A5 (es) 1989-10-13

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