CN102159238A - 抑制病理性血管发生作用的组合物 - Google Patents
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- CN102159238A CN102159238A CN2009801372193A CN200980137219A CN102159238A CN 102159238 A CN102159238 A CN 102159238A CN 2009801372193 A CN2009801372193 A CN 2009801372193A CN 200980137219 A CN200980137219 A CN 200980137219A CN 102159238 A CN102159238 A CN 102159238A
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- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
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Abstract
本发明提供一种抑制病理性血管发生作用和/或细胞增生性疾病的医药组合物。本发明的医药组合物包括有效量的LECT2蛋白或其类似物，以及药学上可接受的载体。
Description
PCT国内申请，说明书已公开。
Claims (1)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13663508P | 2008-09-22 | 2008-09-22 | |
| US61/136,635 | 2008-09-22 | ||
| PCT/CN2009/074086 WO2010031361A1 (zh) | 2008-09-22 | 2009-09-22 | 抑制病理性血管发生作用的组合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102159238A true CN102159238A (zh) | 2011-08-17 |
Family
ID=42039102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009801372193A Pending CN102159238A (zh) | 2008-09-22 | 2009-09-22 | 抑制病理性血管发生作用的组合物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20120071405A1 (zh) |
| EP (1) | EP2347761A4 (zh) |
| JP (1) | JP2012502934A (zh) |
| KR (1) | KR20110092270A (zh) |
| CN (1) | CN102159238A (zh) |
| TW (1) | TW201012473A (zh) |
| WO (1) | WO2010031361A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102552882A (zh) * | 2011-12-22 | 2012-07-11 | 宁波大学 | Lect2蛋白及lect2蛋白变体在制药中应用 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102802658A (zh) * | 2009-12-21 | 2012-11-28 | 台湾东洋药品工业股份有限公司 | 白细胞衍生趋化因子2于肿瘤细胞内降低肝细胞生长因子受体的磷酸化相关的方法与组合物 |
| CN102559739B (zh) * | 2012-01-20 | 2014-06-25 | 宁波大学 | 重组人源lect2蛋白在毕赤酵母中的表达及纯化方法 |
| WO2017110425A1 (ja) * | 2015-12-22 | 2017-06-29 | ロート製薬株式会社 | 肝疾患治療剤及び肝疾患を治療する方法 |
| CN110646615B (zh) * | 2019-08-27 | 2021-07-13 | 南方医科大学 | 肝纤维化的生物学标志物、治疗靶点及其用途 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1785426A (zh) * | 2005-10-27 | 2006-06-14 | 南京大学 | 一种抑制肿瘤血管新生的方法 |
| CN101065486A (zh) * | 2004-11-02 | 2007-10-31 | 马德里自治大学 | 多功能和多价的血管生成抑制剂 |
| WO2008027055A1 (en) * | 2006-08-31 | 2008-03-06 | Abraxis Bioscience, Llc | Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3637087B2 (ja) * | 1994-11-28 | 2005-04-06 | 和男 鈴木 | 新規な白血球活性化因子 |
| JP4378439B2 (ja) * | 1998-12-22 | 2009-12-09 | 国立感染症研究所長 | 骨吸収抑制剤 |
-
2009
- 2009-09-18 TW TW098131497A patent/TW201012473A/zh unknown
- 2009-09-22 US US13/120,101 patent/US20120071405A1/en not_active Abandoned
- 2009-09-22 CN CN2009801372193A patent/CN102159238A/zh active Pending
- 2009-09-22 JP JP2011527194A patent/JP2012502934A/ja not_active Withdrawn
- 2009-09-22 EP EP09814081A patent/EP2347761A4/en not_active Withdrawn
- 2009-09-22 KR KR1020117009131A patent/KR20110092270A/ko not_active Application Discontinuation
- 2009-09-22 WO PCT/CN2009/074086 patent/WO2010031361A1/zh active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101065486A (zh) * | 2004-11-02 | 2007-10-31 | 马德里自治大学 | 多功能和多价的血管生成抑制剂 |
| CN1785426A (zh) * | 2005-10-27 | 2006-06-14 | 南京大学 | 一种抑制肿瘤血管新生的方法 |
| WO2008027055A1 (en) * | 2006-08-31 | 2008-03-06 | Abraxis Bioscience, Llc | Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases |
Non-Patent Citations (2)
| Title |
|---|
| YU-LING WU ET AL.: "The roles of leukocyte cell-derived chemotaxin 2 （LECT2） in hepatocellular carcinoma invasion and angiogenesis", 《PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL MEETING》 * |
| 张晓实: "肿瘤血管生成抑制剂研究进展", 《癌症》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102552882A (zh) * | 2011-12-22 | 2012-07-11 | 宁波大学 | Lect2蛋白及lect2蛋白变体在制药中应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010031361A1 (zh) | 2010-03-25 |
| KR20110092270A (ko) | 2011-08-17 |
| US20120071405A1 (en) | 2012-03-22 |
| JP2012502934A (ja) | 2012-02-02 |
| TW201012473A (en) | 2010-04-01 |
| EP2347761A4 (en) | 2012-07-04 |
| EP2347761A1 (en) | 2011-07-27 |
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