CN102159197A - 治疗骨关节炎的组合物和方法 - Google Patents

治疗骨关节炎的组合物和方法 Download PDF

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Publication number
CN102159197A
CN102159197A CN2009801374555A CN200980137455A CN102159197A CN 102159197 A CN102159197 A CN 102159197A CN 2009801374555 A CN2009801374555 A CN 2009801374555A CN 200980137455 A CN200980137455 A CN 200980137455A CN 102159197 A CN102159197 A CN 102159197A
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China
Prior art keywords
composition
genes
animal
animals
osteoarthritis
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Pending
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CN2009801374555A
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English (en)
Chinese (zh)
Inventor
R·M·杨卡
N·Z·弗兰茨
高向明
S·阿尔穆拉尼
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Hills Pet Nutrition Inc
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Hills Pet Nutrition Inc
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Publication of CN102159197A publication Critical patent/CN102159197A/zh
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A23K20/30—Oligoelements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN2009801374555A 2008-07-18 2009-07-20 治疗骨关节炎的组合物和方法 Pending CN102159197A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8218508P 2008-07-18 2008-07-18
US61/082185 2008-07-18
PCT/US2009/051169 WO2010009474A1 (en) 2008-07-18 2009-07-20 Compositions and methods for treating osteoarthritis

Publications (1)

Publication Number Publication Date
CN102159197A true CN102159197A (zh) 2011-08-17

Family

ID=41059867

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801374555A Pending CN102159197A (zh) 2008-07-18 2009-07-20 治疗骨关节炎的组合物和方法

Country Status (12)

Country Link
US (1) US9629382B2 (https=)
EP (1) EP2323638B1 (https=)
JP (2) JP2011528668A (https=)
CN (1) CN102159197A (https=)
AU (1) AU2009270718B2 (https=)
BR (1) BRPI0915986A2 (https=)
CA (1) CA2731067C (https=)
DK (1) DK2323638T3 (https=)
ES (1) ES2480193T3 (https=)
RU (1) RU2619553C2 (https=)
WO (1) WO2010009474A1 (https=)
ZA (1) ZA201101055B (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107412240A (zh) * 2017-07-24 2017-12-01 冯纪敏 一种组合物及其应用
CN109266738A (zh) * 2018-11-19 2019-01-25 山西中医药大学 类风湿关节炎大鼠炎症因子检测引物及其方法
CN109680046A (zh) * 2019-01-17 2019-04-26 浙江大学 骨关节炎第一亚型的生物标记物以及用途
EP3709817B1 (en) * 2017-11-17 2022-11-16 Hill's Pet Nutrition, Inc. Compositions comprising omega-3 polyunsaturated and medium chain fatty acids

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* Cited by examiner, † Cited by third party
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US9629382B2 (en) 2008-07-18 2017-04-25 Hill's Pet Nutrition, Inc. Compositions and methods for treating osteoarthritis
US20110159500A1 (en) * 2009-12-29 2011-06-30 Hill's Pet Nutrition, Inc. Compositions including ginger for the amelioration or prevention of inflammatory conditions
CN102138961A (zh) * 2010-02-02 2011-08-03 北京绿色金可生物技术股份有限公司 黑豆皮提取物在预防和治疗骨关节炎的产品中的应用
CA2795575C (en) * 2010-05-12 2017-02-28 Hill's Pet Nutrition, Inc. Methods for the diagnosis, control and prophylaxis of inflammation and mitigation of inflammatory conditions in canines
BR112012025772A2 (pt) * 2010-05-12 2015-09-22 Hills Pet Nutrition Inc métodos de controle e profilaxia de inflamação e mitigação de condições inflamatórias em animais de estimação
WO2011143102A1 (en) * 2010-05-12 2011-11-17 Hill's Pet Nutrition, Inc. Methods of diagnosis, control and prophylaxis of inflammation and mitigation of inflammatory conditions in felines
US20130263294A1 (en) * 2010-09-20 2013-10-03 Bioiberica, S.A. Markers for joint displasia, osteoarthritis and conditions secondary thereto
WO2012150504A1 (en) * 2011-05-05 2012-11-08 Life Science Nutrition As Performance enhancing compositions and methods of use
BR112014007947A2 (pt) * 2011-10-03 2017-04-18 Univ Los Andes método para monitoramento, diagnóstico e/ou prognóstico de distúrbios relacionados à hipoxia usando nfat5
CN104039823A (zh) 2011-12-19 2014-09-10 希尔氏宠物营养品公司 用于诊断和治疗伴侣动物的甲状腺机能亢进的组合物和方法
US20140220006A1 (en) * 2013-02-01 2014-08-07 Meso Scale Technologies, Llc Lung cancer biomarkers
KR20250156824A (ko) * 2015-01-06 2025-11-03 데이비드 버톤 모바일 웨어러블 모니터링 시스템
PL3280423T3 (pl) * 2015-04-08 2023-12-27 Microvascular Health Solutions, LLC Kompozycje i sposoby do synergistycznego leczenia glikokaliksu
EP3446127A4 (en) * 2016-04-20 2020-01-22 Crescendo Bioscience, Inc. BIOMARKERS AND METHODS FOR ASSESSING RESPONSE TO INFLAMMATORY DISEASE TREATMENT
US20190316096A1 (en) * 2016-12-28 2019-10-17 Kyowa Hakko Kirin Co Method for selecting cell
EP3612570A4 (en) 2017-04-17 2021-01-13 The University of Chicago POLYMERIC MATERIALS FOR THE ADMINISTRATION OF SHORT-CHAIN FATTY ACIDS TO THE INTESTINE FOR HUMAN HEALTH AND DISEASE TREATMENT APPLICATIONS
JP7402225B2 (ja) 2018-05-11 2023-12-20 ロード アイランド ホスピタル ヌクレオシド系逆転写酵素阻害剤を用いて関節障害を処置するための組成物および方法
CN109965124A (zh) * 2019-03-29 2019-07-05 华熙生物科技股份有限公司 一种宠物食品及其制备方法
CN110511937B (zh) * 2019-08-05 2021-07-09 华南农业大学 Snf7基因及其防治瓢虫的应用
US20230030915A1 (en) * 2019-12-16 2023-02-02 Hill's Pet Nutrition, Inc. Pet Food Compositions
US20240382518A1 (en) * 2021-09-17 2024-11-21 Seoul National University R&Db Foundation Pharmaceutical composition and health functional food for prevention or treatment of osteoarthritis

Citations (5)

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US20060073192A1 (en) * 2004-02-09 2006-04-06 Friesen Kim G Composition and method for use in cartilage affecting conditions
WO2006053010A2 (en) * 2004-11-09 2006-05-18 Hill's Pet Nutrition, Inc. Use of antioxidants for gene modulation
WO2007002837A2 (en) * 2005-06-29 2007-01-04 Hill's Pet Nutrition, Inc. Methods and compositions for the prevention and treatement of inflammatory disease
WO2007079301A2 (en) * 2005-12-28 2007-07-12 Hill's Pet Nutrition, Inc. Method of diagnosing a body weight condition or predisposition in an animal
US20070253941A1 (en) * 2006-04-28 2007-11-01 Naidu A Satyanarayan Coenzyme Q10, lactoferrin and angiogenin compositions and uses thereof

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ES2210705T5 (es) * 1998-03-19 2011-02-15 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composición combinada que comprende una l-carnitina o una alcanoil-l-carnitina, un glucosaminoglucano y/o un constituyente del mismo.
US6506785B2 (en) * 1998-05-22 2003-01-14 Pfizer, Inc. Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives
PL346860A1 (en) * 1998-09-08 2002-03-11 Monsanto Co Methods of treating osteoarthritis with inducible nitric oxide synthase inhibitors
US6534261B1 (en) 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US6277842B1 (en) * 2000-10-17 2001-08-21 James Alexander Carthron Dietary supplemental method for fat and weight reduction
US20020099032A1 (en) * 2000-11-10 2002-07-25 Kiyotsugu Higashi Preparations and method of producing the same
WO2005000331A2 (en) * 2003-06-04 2005-01-06 Mucosal Therapeutics, Inc. Compositions for the treatment and prevention of degenerative joint disorders
US8633247B2 (en) 2003-08-11 2014-01-21 Hill's Pet Nutrition, Inc. Method for decreasing cartilage damage in dogs
ES2310757T3 (es) * 2003-08-11 2009-01-16 Hill's Pet Nutrition Inc. Acidos grasos omega-3 para el tratamiento de la artrosis canina.
US8633246B2 (en) 2003-08-11 2014-01-21 Hill's Pet Nutrition, Inc. Omega-3 fatty acids for osteoarthritis
JP5667737B2 (ja) * 2004-07-01 2015-02-12 ネステク ソシエテ アノニム イヌ変形性関節症食餌製剤
US9629382B2 (en) 2008-07-18 2017-04-25 Hill's Pet Nutrition, Inc. Compositions and methods for treating osteoarthritis

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060073192A1 (en) * 2004-02-09 2006-04-06 Friesen Kim G Composition and method for use in cartilage affecting conditions
WO2006053010A2 (en) * 2004-11-09 2006-05-18 Hill's Pet Nutrition, Inc. Use of antioxidants for gene modulation
WO2007002837A2 (en) * 2005-06-29 2007-01-04 Hill's Pet Nutrition, Inc. Methods and compositions for the prevention and treatement of inflammatory disease
WO2007079301A2 (en) * 2005-12-28 2007-07-12 Hill's Pet Nutrition, Inc. Method of diagnosing a body weight condition or predisposition in an animal
US20070253941A1 (en) * 2006-04-28 2007-11-01 Naidu A Satyanarayan Coenzyme Q10, lactoferrin and angiogenin compositions and uses thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107412240A (zh) * 2017-07-24 2017-12-01 冯纪敏 一种组合物及其应用
EP3709817B1 (en) * 2017-11-17 2022-11-16 Hill's Pet Nutrition, Inc. Compositions comprising omega-3 polyunsaturated and medium chain fatty acids
CN109266738A (zh) * 2018-11-19 2019-01-25 山西中医药大学 类风湿关节炎大鼠炎症因子检测引物及其方法
CN109680046A (zh) * 2019-01-17 2019-04-26 浙江大学 骨关节炎第一亚型的生物标记物以及用途
CN109680046B (zh) * 2019-01-17 2021-08-10 浙江大学 骨关节炎第一亚型的生物标记物以及用途

Also Published As

Publication number Publication date
US20110183006A1 (en) 2011-07-28
JP2014237709A (ja) 2014-12-18
US9629382B2 (en) 2017-04-25
EP2323638B1 (en) 2014-05-07
AU2009270718B2 (en) 2012-09-06
EP2323638A1 (en) 2011-05-25
WO2010009474A1 (en) 2010-01-21
ZA201101055B (en) 2014-07-30
RU2619553C2 (ru) 2017-05-16
ES2480193T3 (es) 2014-07-25
BRPI0915986A2 (pt) 2015-11-03
CA2731067A1 (en) 2010-01-21
JP6047128B2 (ja) 2016-12-21
JP2011528668A (ja) 2011-11-24
AU2009270718A1 (en) 2010-01-21
RU2011106033A (ru) 2012-08-27
CA2731067C (en) 2013-10-01
DK2323638T3 (da) 2014-08-11

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Application publication date: 20110817