CA2731067C - Compositions and methods for treating osteoarthritis - Google Patents

Compositions and methods for treating osteoarthritis Download PDF

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Publication number
CA2731067C
CA2731067C CA2731067A CA2731067A CA2731067C CA 2731067 C CA2731067 C CA 2731067C CA 2731067 A CA2731067 A CA 2731067A CA 2731067 A CA2731067 A CA 2731067A CA 2731067 C CA2731067 C CA 2731067C
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Prior art keywords
mrna
predicted
protein
similar
column
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CA2731067A
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English (en)
French (fr)
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CA2731067A1 (en
Inventor
Ryan Michael Yamka
Nolan Zebulon Frantz
Xiangming Gao
Samer Al Murrani
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Hills Pet Nutrition Inc
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Hills Pet Nutrition Inc
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Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/40Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/30Oligoelements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2731067A 2008-07-18 2009-07-20 Compositions and methods for treating osteoarthritis Active CA2731067C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8218508P 2008-07-18 2008-07-18
US61/082,185 2008-07-18
PCT/US2009/051169 WO2010009474A1 (en) 2008-07-18 2009-07-20 Compositions and methods for treating osteoarthritis

Publications (2)

Publication Number Publication Date
CA2731067A1 CA2731067A1 (en) 2010-01-21
CA2731067C true CA2731067C (en) 2013-10-01

Family

ID=41059867

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2731067A Active CA2731067C (en) 2008-07-18 2009-07-20 Compositions and methods for treating osteoarthritis

Country Status (12)

Country Link
US (1) US9629382B2 (https=)
EP (1) EP2323638B1 (https=)
JP (2) JP2011528668A (https=)
CN (1) CN102159197A (https=)
AU (1) AU2009270718B2 (https=)
BR (1) BRPI0915986A2 (https=)
CA (1) CA2731067C (https=)
DK (1) DK2323638T3 (https=)
ES (1) ES2480193T3 (https=)
RU (1) RU2619553C2 (https=)
WO (1) WO2010009474A1 (https=)
ZA (1) ZA201101055B (https=)

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* Cited by examiner, † Cited by third party
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US9629382B2 (en) 2008-07-18 2017-04-25 Hill's Pet Nutrition, Inc. Compositions and methods for treating osteoarthritis
US20110159500A1 (en) * 2009-12-29 2011-06-30 Hill's Pet Nutrition, Inc. Compositions including ginger for the amelioration or prevention of inflammatory conditions
CN102138961A (zh) * 2010-02-02 2011-08-03 北京绿色金可生物技术股份有限公司 黑豆皮提取物在预防和治疗骨关节炎的产品中的应用
CA2795575C (en) * 2010-05-12 2017-02-28 Hill's Pet Nutrition, Inc. Methods for the diagnosis, control and prophylaxis of inflammation and mitigation of inflammatory conditions in canines
BR112012025772A2 (pt) * 2010-05-12 2015-09-22 Hills Pet Nutrition Inc métodos de controle e profilaxia de inflamação e mitigação de condições inflamatórias em animais de estimação
WO2011143102A1 (en) * 2010-05-12 2011-11-17 Hill's Pet Nutrition, Inc. Methods of diagnosis, control and prophylaxis of inflammation and mitigation of inflammatory conditions in felines
US20130263294A1 (en) * 2010-09-20 2013-10-03 Bioiberica, S.A. Markers for joint displasia, osteoarthritis and conditions secondary thereto
WO2012150504A1 (en) * 2011-05-05 2012-11-08 Life Science Nutrition As Performance enhancing compositions and methods of use
BR112014007947A2 (pt) * 2011-10-03 2017-04-18 Univ Los Andes método para monitoramento, diagnóstico e/ou prognóstico de distúrbios relacionados à hipoxia usando nfat5
CN104039823A (zh) 2011-12-19 2014-09-10 希尔氏宠物营养品公司 用于诊断和治疗伴侣动物的甲状腺机能亢进的组合物和方法
US20140220006A1 (en) * 2013-02-01 2014-08-07 Meso Scale Technologies, Llc Lung cancer biomarkers
KR20250156824A (ko) * 2015-01-06 2025-11-03 데이비드 버톤 모바일 웨어러블 모니터링 시스템
PL3280423T3 (pl) * 2015-04-08 2023-12-27 Microvascular Health Solutions, LLC Kompozycje i sposoby do synergistycznego leczenia glikokaliksu
EP3446127A4 (en) * 2016-04-20 2020-01-22 Crescendo Bioscience, Inc. BIOMARKERS AND METHODS FOR ASSESSING RESPONSE TO INFLAMMATORY DISEASE TREATMENT
US20190316096A1 (en) * 2016-12-28 2019-10-17 Kyowa Hakko Kirin Co Method for selecting cell
EP3612570A4 (en) 2017-04-17 2021-01-13 The University of Chicago POLYMERIC MATERIALS FOR THE ADMINISTRATION OF SHORT-CHAIN FATTY ACIDS TO THE INTESTINE FOR HUMAN HEALTH AND DISEASE TREATMENT APPLICATIONS
CN107412240A (zh) * 2017-07-24 2017-12-01 冯纪敏 一种组合物及其应用
AU2017440239B2 (en) * 2017-11-17 2021-06-24 Hill's Pet Nutrition, Inc. Compositions comprising omega-3 polyunsaturated and medium chain fatty acids
JP7402225B2 (ja) 2018-05-11 2023-12-20 ロード アイランド ホスピタル ヌクレオシド系逆転写酵素阻害剤を用いて関節障害を処置するための組成物および方法
CN109266738A (zh) * 2018-11-19 2019-01-25 山西中医药大学 类风湿关节炎大鼠炎症因子检测引物及其方法
CN109680046B (zh) * 2019-01-17 2021-08-10 浙江大学 骨关节炎第一亚型的生物标记物以及用途
CN109965124A (zh) * 2019-03-29 2019-07-05 华熙生物科技股份有限公司 一种宠物食品及其制备方法
CN110511937B (zh) * 2019-08-05 2021-07-09 华南农业大学 Snf7基因及其防治瓢虫的应用
US20230030915A1 (en) * 2019-12-16 2023-02-02 Hill's Pet Nutrition, Inc. Pet Food Compositions
US20240382518A1 (en) * 2021-09-17 2024-11-21 Seoul National University R&Db Foundation Pharmaceutical composition and health functional food for prevention or treatment of osteoarthritis

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Also Published As

Publication number Publication date
US20110183006A1 (en) 2011-07-28
JP2014237709A (ja) 2014-12-18
US9629382B2 (en) 2017-04-25
EP2323638B1 (en) 2014-05-07
AU2009270718B2 (en) 2012-09-06
EP2323638A1 (en) 2011-05-25
WO2010009474A1 (en) 2010-01-21
ZA201101055B (en) 2014-07-30
RU2619553C2 (ru) 2017-05-16
ES2480193T3 (es) 2014-07-25
BRPI0915986A2 (pt) 2015-11-03
CA2731067A1 (en) 2010-01-21
JP6047128B2 (ja) 2016-12-21
JP2011528668A (ja) 2011-11-24
CN102159197A (zh) 2011-08-17
AU2009270718A1 (en) 2010-01-21
RU2011106033A (ru) 2012-08-27
DK2323638T3 (da) 2014-08-11

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