CN102137618B - 组织生物标志物的定量多光谱光声断层摄影(msot) - Google Patents

组织生物标志物的定量多光谱光声断层摄影(msot) Download PDF

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CN102137618B
CN102137618B CN200880130942.4A CN200880130942A CN102137618B CN 102137618 B CN102137618 B CN 102137618B CN 200880130942 A CN200880130942 A CN 200880130942A CN 102137618 B CN102137618 B CN 102137618B
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target tissue
illumination
imaging
tissue
biomarker
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CN102137618A (zh
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D·拉扎斯基
V·恩齐亚赫里斯托斯
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Helmholtz Zentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit und Umwelt GmbH
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN200880130942.4A 2008-07-25 2008-07-25 组织生物标志物的定量多光谱光声断层摄影(msot) Active CN102137618B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2008/006142 WO2010009747A1 (en) 2008-07-25 2008-07-25 Quantitative multi-spectral opto-acoustic tomography (msot) of tissue biomarkers

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CN102137618A CN102137618A (zh) 2011-07-27
CN102137618B true CN102137618B (zh) 2015-06-17

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US (1) US9572497B2 (https=)
EP (1) EP2344019B1 (https=)
JP (1) JP5749164B2 (https=)
CN (1) CN102137618B (https=)
CA (1) CA2731409C (https=)
WO (1) WO2010009747A1 (https=)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7520860B2 (en) 2005-04-13 2009-04-21 Marie G. Johnson Detection of coronary artery disease using an electronic stethoscope
EP2527815B1 (en) 2008-07-25 2014-05-14 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Thermoacoustic imaging with quantitative extraction of an absorption image
JP5749164B2 (ja) 2008-07-25 2015-07-15 ヘルムホルツ・ツェントルム・ミュンヒェン・ドイチェス・フォルシュンクスツェントルム・フューア・ゲズントハイト・ウント・ウムベルト（ゲーエムベーハー）Ｈｅｌｍｈｏｌｔｚ Ｚｅｎｔｒｕｍ ＭｕｅｎｃｈｅｎＤｅｕｔｓｃｈｅｓ Ｆｏｒｓｃｈｕｎｇｓｚｅｎｔｒｕｍ ｆｕｅｒ Ｇｅｓｕｎｄｈｅｉｔ ｕｎｄ Ｕｍｗｅｌｔ （ＧｍｂＨ） 組織バイオマーカーの定量的多重スペクトル光音響トモグラフィ
CN102223840B (zh) * 2008-09-10 2015-03-18 安德拉有限公司 光声成像设备
US9271654B2 (en) 2009-06-29 2016-03-01 Helmholtz Zentrum Munchen Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) Thermoacoustic imaging with quantitative extraction of absorption map
EP2459987A1 (en) * 2009-07-27 2012-06-06 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Imaging device and method for optoacoustic imaging of small animals
EP2359745A1 (en) 2010-02-12 2011-08-24 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Method and device for multi-spectral photonic imaging
JP5693043B2 (ja) * 2010-04-28 2015-04-01 キヤノン株式会社 被検体情報取得装置、被検体情報取得方法
WO2011137247A2 (en) * 2010-04-30 2011-11-03 The Trustees Of Columbia University In The City Of New York System, method and computer-accessible medium for performing attenuation-corrected multispectral luminescence tomography of cerenkov and bioluminescent light sources
EP4238492A3 (en) * 2010-05-28 2023-09-27 The General Hospital Corporation Apparatus, systems, methods and computer-accessible medium for analyzing information regarding cardiovascular disease(s) and function(s)
JP5627360B2 (ja) * 2010-09-14 2014-11-19 キヤノン株式会社 光音響イメージング装置およびその制御方法
US20130109950A1 (en) * 2011-11-02 2013-05-02 Seno Medical Instruments, Inc. Handheld optoacoustic probe
US8686335B2 (en) 2011-12-31 2014-04-01 Seno Medical Instruments, Inc. System and method for adjusting the light output of an optoacoustic imaging system
US9289191B2 (en) 2011-10-12 2016-03-22 Seno Medical Instruments, Inc. System and method for acquiring optoacoustic data and producing parametric maps thereof
JP5875242B2 (ja) * 2010-10-05 2016-03-02 キヤノン株式会社 光音響イメージング用造影剤、及び、それを用いた光音響イメージング方法
CN102175617A (zh) * 2011-01-28 2011-09-07 华南理工大学 一种光强可控光纤耦合光声检测探头
JP5744557B2 (ja) * 2011-02-10 2015-07-08 キヤノン株式会社 音響波取得装置
JP5850633B2 (ja) * 2011-04-12 2016-02-03 キヤノン株式会社 被検体情報取得装置
JP2016209725A (ja) * 2011-05-12 2016-12-15 キヤノン株式会社 被検体情報取得装置及び被検体情報取得方法
JP5743957B2 (ja) * 2011-06-07 2015-07-01 富士フイルム株式会社 光音響画像生成装置及び方法
US20130289381A1 (en) 2011-11-02 2013-10-31 Seno Medical Instruments, Inc. Dual modality imaging system for coregistered functional and anatomical mapping
US20130116538A1 (en) 2011-11-02 2013-05-09 Seno Medical Instruments, Inc. Optoacoustic imaging systems and methods with enhanced safety
US11191435B2 (en) 2013-01-22 2021-12-07 Seno Medical Instruments, Inc. Probe with optoacoustic isolator
SG11201401986WA (en) * 2011-11-02 2014-08-28 Seno Medical Instr Inc Dual modality imaging system for coregistered functional and anatomical mapping
US9733119B2 (en) 2011-11-02 2017-08-15 Seno Medical Instruments, Inc. Optoacoustic component utilization tracking
US20130338475A1 (en) 2012-06-13 2013-12-19 Seno Medical Instruments, Inc. Optoacoustic imaging system with fiber optic cable
US10433732B2 (en) 2011-11-02 2019-10-08 Seno Medical Instruments, Inc. Optoacoustic imaging system having handheld probe utilizing optically reflective material
US20140005544A1 (en) 2011-11-02 2014-01-02 Seno Medical Instruments, Inc. System and method for providing selective channel sensitivity in an optoacoustic imaging system
US11287309B2 (en) 2011-11-02 2022-03-29 Seno Medical Instruments, Inc. Optoacoustic component utilization tracking
US9743839B2 (en) 2011-11-02 2017-08-29 Seno Medical Instruments, Inc. Playback mode in an optoacoustic imaging system
US9814394B2 (en) 2011-11-02 2017-11-14 Seno Medical Instruments, Inc. Noise suppression in an optoacoustic system
US9445786B2 (en) 2011-11-02 2016-09-20 Seno Medical Instruments, Inc. Interframe energy normalization in an optoacoustic imaging system
US9730587B2 (en) 2011-11-02 2017-08-15 Seno Medical Instruments, Inc. Diagnostic simulator
TWI435712B (zh) * 2011-12-14 2014-05-01 Univ Nat Chiao Tung 擴散式光學斷層掃描裝置及擴散式光學斷層掃描方法
JP5943598B2 (ja) 2011-12-26 2016-07-05 キヤノン株式会社 被検体情報取得装置
WO2013134772A2 (en) * 2012-03-09 2013-09-12 Seno Medical Instruments, Inc. Statistical mapping in an optoacoustic imaging system
US9297752B2 (en) 2012-04-10 2016-03-29 Advanced Telecommunications Research Institute International Object observing apparatus, object observing method, and storage medium
KR101974580B1 (ko) * 2012-05-03 2019-05-02 삼성전자주식회사 레이저 유도 초음파 장치 및 이를 이용한 영상 생성 방법
US20150366458A1 (en) 2012-05-07 2015-12-24 Helmholtz Zentrum Munchen Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) Apparatus and method for frequency-domain thermo-acoustic tomographic imaging
EP2742854B1 (en) 2012-12-11 2021-03-10 iThera Medical GmbH Handheld device and method for tomographic optoacoustic imaging of an object
EP2754388B1 (en) * 2013-01-15 2020-09-09 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH System and method for quality-enhanced high-rate optoacoustic imaging of an object
AU2014237034A1 (en) 2013-03-15 2015-09-24 Seno Medical Instruments, Inc. System and method for diagnostic vector classification support
JP2015000288A (ja) * 2013-06-18 2015-01-05 キヤノン株式会社 被検体情報取得装置およびその制御方法ならびに音響信号取得装置およびその制御方法
JP2015029550A (ja) * 2013-07-31 2015-02-16 船井電機株式会社 光音響画像化装置
CN103393408B (zh) * 2013-08-20 2015-12-02 中国科学院自动化研究所 一种光声和荧光循环互提升成像方法
US9953417B2 (en) 2013-10-04 2018-04-24 The University Of Manchester Biomarker method
US9519823B2 (en) * 2013-10-04 2016-12-13 The University Of Manchester Biomarker method
EP3054853A4 (en) 2013-10-11 2017-05-17 Seno Medical Instruments, Inc. Systems and methods for component separation in medical imaging
JP2015092914A (ja) * 2013-11-08 2015-05-18 キヤノン株式会社 被検体情報取得装置および音響波受信装置
SG10201804772UA (en) 2013-12-06 2018-07-30 Agency Science Tech & Res Method of imaging living tissue
US9670522B2 (en) * 2014-01-08 2017-06-06 University Of South Carolina Quantitative acoustic contrast tomography for studying fungal growth and toxicity
US10258241B2 (en) 2014-02-27 2019-04-16 Seno Medical Instruments, Inc. Probe adapted to control blood flow through vessels during imaging and method of use of same
US9959477B2 (en) 2014-03-03 2018-05-01 The Board Of Trustees Of The Leland Stanford Junior University Mapping of blood vessels for biometric authentication
WO2015174085A1 (en) * 2014-05-14 2015-11-19 Canon Kabushiki Kaisha Photoacoustic apparatus
JP6587410B2 (ja) * 2014-05-19 2019-10-09 キヤノン株式会社 被検体情報取得装置および信号処理方法
US9092691B1 (en) * 2014-07-18 2015-07-28 Median Technologies System for computing quantitative biomarkers of texture features in tomographic images
JP6152079B2 (ja) * 2014-08-29 2017-06-21 プレキシオン株式会社 光音響画像化装置用プローブ
EP3212065B1 (en) 2014-10-30 2022-03-30 Seno Medical Instruments, Inc. Opto-acoustic imaging system with detection of relative orientation of light source and acoustic receiver using acoustic waves
EP3056137B1 (en) 2015-02-13 2017-11-01 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH Device and method for multispectral optoacoustic imaging
CA2978042A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Tissue analysis by mass spectrometry or ion mobility spectrometry
EP3726562B1 (en) 2015-03-06 2023-12-20 Micromass UK Limited Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue
GB2552602B (en) 2015-03-06 2020-12-30 Micromass Ltd Desorption electrospray ionisation mass spectrometry ("DESI-MS") analysis of swabs
KR101956496B1 (ko) 2015-03-06 2019-03-08 마이크로매스 유케이 리미티드 전기수술 응용분야에 대한 액체 트랩 또는 세퍼레이터
WO2016142692A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Spectrometric analysis
US11139156B2 (en) 2015-03-06 2021-10-05 Micromass Uk Limited In vivo endoscopic tissue identification tool
GB2554181B (en) 2015-03-06 2021-09-08 Micromass Ltd Inlet instrumentation for ion analyser coupled to rapid evaporative ionisation mass spectrometry ("REIMS") device
EP3741303A3 (en) 2015-03-06 2020-12-30 Micromass UK Limited Chemically guided ambient ionisation mass spectrometry
EP3265818B1 (en) * 2015-03-06 2020-02-12 Micromass UK Limited Imaging guided ambient ionisation mass spectrometry
DE202016008460U1 (de) 2015-03-06 2018-01-22 Micromass Uk Limited Zellpopulationsanalyse
CN112964625B (zh) 2015-03-06 2024-06-07 英国质谱公司 细胞群体分析
GB2554206B (en) 2015-03-06 2021-03-24 Micromass Ltd Spectrometric analysis of microbes
CA2978165A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Improved ionisation of gaseous samples
WO2016142685A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Collision surface for improved ionisation
EP3269309B1 (en) * 2015-03-13 2018-12-12 FUJIFILM Corporation Photoacoustic measurement device and probe
JP2017012485A (ja) * 2015-07-01 2017-01-19 キヤノン株式会社 生体マーカおよび被検体情報取得装置
JP6824636B2 (ja) * 2015-07-21 2021-02-03 キヤノン株式会社 被検体情報取得装置および被検体情報取得方法
WO2017014167A1 (en) * 2015-07-21 2017-01-26 Canon Kabushiki Kaisha Object information acquiring apparatus and object information acquiring method
JP2017055838A (ja) * 2015-09-14 2017-03-23 プレキシオン株式会社 光音響画像化装置
GB201517195D0 (en) 2015-09-29 2015-11-11 Micromass Ltd Capacitively coupled reims technique and optically transparent counter electrode
WO2017167841A1 (en) * 2016-03-30 2017-10-05 Koninklijke Philips N.V. Tissue and vascular pathway mapping utilizing photoacoustic and ultrasound techniques
EP3443354B1 (en) 2016-04-14 2025-08-20 Micromass UK Limited Spectrometric analysis of plants
US12036000B2 (en) * 2016-05-27 2024-07-16 The Regents Of The University Of Michigan Method of photoacoustic imaging intraocular tumors including back-projection reconstruction to measure heterogeneity
US10709333B2 (en) * 2016-07-25 2020-07-14 PhotoSound Technologies, Inc. Instrument for acquiring co-registered orthogonal fluorescence and photoacoustic volumetric projections of tissue and methods of its use
US9976997B2 (en) * 2016-10-17 2018-05-22 Shimadzu Corporation Data processing device for quantitation
RU2649048C1 (ru) * 2016-11-25 2018-03-29 Самсунг Электроникс Ко., Лтд. Система компактного спектрометра, предназначенного для неинвазивного измерения спектров поглощения и пропускания образцов биологической ткани
EP3375353A1 (en) 2017-03-16 2018-09-19 Universität Zürich Photoacoustic imaging of inflamed tissue
EP3413235A1 (en) * 2017-06-08 2018-12-12 Moqi Inc. System and method for fingerprint recognition
JP7251873B2 (ja) * 2018-01-11 2023-04-04 センター フォー アイ リサーチ オーストラリア リミテッド 組織のバイオマーカを定量化するための方法及びシステム
CN108375547B (zh) * 2018-01-12 2020-08-18 华南师范大学 多光谱光声和光学相干层析双模态成像装置及方法
WO2019144232A1 (en) 2018-01-25 2019-08-01 Fadhel Muhannad N Method and system for fluence matching in photoacoustic imaging
JP7279957B2 (ja) * 2018-04-04 2023-05-23 トモウェーブ ラボラトリーズ，インク． 定量的撮像システムおよびその使用
JP7457710B2 (ja) * 2018-08-24 2024-03-28 デジタル ハーモニック エルエルシー 時間にわたる生体細胞及び生体組織の振動スペクトルを測定するシステム及び方法
CN115917369A (zh) * 2020-04-23 2023-04-04 加利福尼亚大学董事会 超快光场断层摄影
EP3932295A1 (en) 2020-06-30 2022-01-05 Universität Zürich Optoacoustic tomography method of a living organism, 2d- or 3d opotacoustic images, 2d- or 3d blood flow and light fluence images and a photoabsorbing agent for the use in an optoacoustic method
US20240023813A1 (en) * 2020-09-14 2024-01-25 Research Development Foundation Systems and methods for ultrasound and photoacoustic guidance of coronary procedures
CN112200883B (zh) * 2020-11-03 2023-03-24 华北电力大学（保定） 一种定量血管内光学相干层析成像方法及系统
CN115137358B (zh) * 2021-03-29 2024-05-14 上海近观科技有限责任公司 一种皮下无创检测装置、信号收集系统及方法
CN116269203A (zh) * 2021-12-09 2023-06-23 深圳迈瑞生物医疗电子股份有限公司 光声成像系统中的激光能量校正方法及提示方法、光声成像系统
CN114027802A (zh) * 2022-01-10 2022-02-11 杭州纬壹医疗科技有限公司 一种扩散光学层析成像系统
CN115128010B (zh) * 2022-07-21 2025-04-29 清华大学 一种物质成分比例确定方法及装置
CN115479927B (zh) * 2022-08-24 2025-09-30 中国科学院宁波材料技术与工程研究所 一种内窥镜用荧光校色卡片及其制备方法和应用
CN115607108B (zh) * 2022-09-30 2024-10-29 西北大学 一种基于表面测量信号盲源分离的多目标重建方法
CN117017280B (zh) * 2023-07-24 2024-03-19 西南交通大学 基于可穿戴柔性近红外光声/超声双模态成像系统及方法
US12607562B2 (en) 2024-05-10 2026-04-21 Digital Harmonic Llc System and method for measuring, storing, collating, and displaying vibrational spectra of living cells and tissue using digital comparative precision noise reduction
CN121213550B (zh) * 2025-11-26 2026-03-20 上海太易检测技术股份有限公司 基于双窄波段红外图像的核桃分选方法、装置及介质

Family Cites Families (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4255971A (en) 1978-11-01 1981-03-17 Allan Rosencwaig Thermoacoustic microscopy
CH643397A5 (de) 1979-09-20 1984-05-30 Ibm Raster-tunnelmikroskop.
US4385634A (en) 1981-04-24 1983-05-31 University Of Arizona Foundation Radiation-induced thermoacoustic imaging
EP0111386B1 (en) 1982-10-26 1987-11-19 University Of Aberdeen Ultrasound hyperthermia unit
FR2550678B1 (fr) 1983-08-11 1989-02-17 Cit Alcatel Centre satellite numerique de raccordement d'abonnes
US4770183A (en) 1986-07-03 1988-09-13 Advanced Magnetics Incorporated Biologically degradable superparamagnetic particles for use as nuclear magnetic resonance imaging agents
DE3826709C2 (de) 1987-08-05 1994-12-22 Toshiba Kawasaki Kk Ultraschall-Therapiegerät
DE69131528T2 (de) 1990-05-30 2000-05-04 Hitachi, Ltd. Verfahren und Vorrichtung zur Behandlung eines sehr kleinen Bereichs einer Probe
US6263221B1 (en) 1991-01-24 2001-07-17 Non-Invasive Technology Quantitative analyses of biological tissue using phase modulation spectroscopy
US5411730A (en) 1993-07-20 1995-05-02 Research Corporation Technologies, Inc. Magnetic microparticles
US5840023A (en) * 1996-01-31 1998-11-24 Oraevsky; Alexander A. Optoacoustic imaging for medical diagnosis
JPH09219563A (ja) * 1996-02-09 1997-08-19 Hitachi Ltd 半導体光素子とそれを用いた応用システム
US6173604B1 (en) 1996-09-20 2001-01-16 The Regents Of The University Of California Scanning evanescent electro-magnetic microscope
US5713356A (en) 1996-10-04 1998-02-03 Optosonics, Inc. Photoacoustic breast scanner
WO1998037811A1 (en) 1997-02-28 1998-09-03 Electro-Optical Sciences, Inc. Systems and methods for the multispectral imaging and characterization of skin tissue
US6428171B1 (en) * 1997-05-16 2002-08-06 Olympus Optical Co., Ltd. Height measuring apparatus
GB9712524D0 (en) 1997-06-16 1997-08-20 Nycomed Imaging As Method
US5928151A (en) 1997-08-22 1999-07-27 Acuson Corporation Ultrasonic system and method for harmonic imaging in three dimensions
US6477398B1 (en) 1997-11-13 2002-11-05 Randell L. Mills Resonant magnetic susceptibility imaging (ReMSI)
US6070093A (en) * 1997-12-02 2000-05-30 Abbott Laboratories Multiplex sensor and method of use
US6526298B1 (en) * 1998-05-18 2003-02-25 Abbott Laboratories Method for the non-invasive determination of analytes in a selected volume of tissue
US6662030B2 (en) * 1998-05-18 2003-12-09 Abbott Laboratories Non-invasive sensor having controllable temperature feature
US6216025B1 (en) 1999-02-02 2001-04-10 Optosonics, Inc. Thermoacoustic computed tomography scanner
US6760609B2 (en) 1999-07-14 2004-07-06 Providence Health System - Oregon Adaptive calibration pulsed oximetry method and device
DE60016761T2 (de) 1999-08-02 2005-12-15 Zetetic Institute, Tucson Interferometrische konfokale nahfeld-abtastmikroskopie
US6567688B1 (en) 1999-08-19 2003-05-20 The Texas A&M University System Methods and apparatus for scanning electromagnetically-induced thermoacoustic tomography
US6424410B1 (en) * 1999-08-27 2002-07-23 Maui Innovative Peripherals, Inc. 3D navigation system using complementary head-mounted and stationary infrared beam detection units
US6834063B2 (en) 2000-01-06 2004-12-21 Raytheon Company Efficient angle tunable output from a monolithic serial KTA optical parametric oscillator
US20020163735A1 (en) 2000-01-11 2002-11-07 Gunther Detlef Radially homogeneous high energy density UV sample ablating laser radiation in "pure" solid to gas sample preparation , for analysis by ICP-MS and ICP-OES
US6180087B1 (en) 2000-01-18 2001-01-30 Mallinckrodt Inc. Tunable indocyanine dyes for biomedical applications
US6751490B2 (en) * 2000-03-01 2004-06-15 The Board Of Regents Of The University Of Texas System Continuous optoacoustic monitoring of hemoglobin concentration and hematocrit
US6847168B1 (en) 2000-08-01 2005-01-25 Calabazas Creek Research, Inc. Electron gun for a multiple beam klystron using magnetic focusing with a magnetic field corrector
US6754519B1 (en) 2000-11-24 2004-06-22 Elgems Ltd. Multimodality imaging system
US6615063B1 (en) 2000-11-27 2003-09-02 The General Hospital Corporation Fluorescence-mediated molecular tomography
US20020073717A1 (en) 2000-12-19 2002-06-20 Dean David E. MR scanner including liquid cooled RF coil and method
US7498564B2 (en) 2001-02-06 2009-03-03 University Of Bristol Of Senate House Resonant scanning near-field optical microscope
DE10113661A1 (de) 2001-03-21 2002-09-26 Philips Corp Intellectual Pty Katheter zur Anwendung in einem Magnetresonanz-Bildgerät
US6498492B1 (en) 2001-03-23 2002-12-24 Rosemount Analytical Inc. Process of measuring conductivity using a pH analyzer
US6574490B2 (en) * 2001-04-11 2003-06-03 Rio Grande Medical Technologies, Inc. System for non-invasive measurement of glucose in humans
US6490470B1 (en) 2001-06-19 2002-12-03 Optosonics, Inc. Thermoacoustic tissue scanner
GB0126804D0 (en) 2001-11-07 2002-01-02 Univ London Flow velocity measurement
US6700459B2 (en) 2002-05-29 2004-03-02 Superconductor Technologies, Inc. Dual-mode bandpass filter with direct capacitive couplings and far-field suppression structures
WO2003102558A1 (en) 2002-06-04 2003-12-11 Visen Medical, Inc. Imaging volumes with arbitrary geometries in contact and non-contact tomography
US7005653B1 (en) 2002-06-18 2006-02-28 Nanopoint, Inc. Near-field intra-cellular apertureless tomographic imaging
US20040059265A1 (en) * 2002-09-12 2004-03-25 The Regents Of The University Of California Dynamic acoustic focusing utilizing time reversal
US7774042B2 (en) 2002-09-26 2010-08-10 Senco Brands, Inc. Tissue scanner
US7245789B2 (en) 2002-10-07 2007-07-17 Vascular Imaging Corporation Systems and methods for minimally-invasive optical-acoustic imaging
JP2006516207A (ja) 2003-01-13 2006-06-29 グルコン インク 光音響分析方法及び装置
WO2004068405A2 (en) 2003-01-25 2004-08-12 Oraevsky Alexander A High contrast optoacoustical imaging using nanoparticles
EP1593095B1 (en) 2003-02-05 2019-04-17 The General Hospital Corporation Method and system for free space optical tomography of diffuse media
US7551957B2 (en) 2003-03-06 2009-06-23 Bioelectronics Corp. Electromagnetic therapy device and methods
US7720525B2 (en) * 2003-03-12 2010-05-18 New Art Advanced Research Technologies Inc. Method and apparatus for combining continuous wave and time domain optical imaging
IES20030396A2 (en) 2003-05-23 2004-11-17 Univ Dublin City A method and apparatus for analysis of semiconductor materials using photoacoustic spectroscopy techniques
JP2004351023A (ja) 2003-05-30 2004-12-16 Olympus Corp 光音響プローブ
US7725151B2 (en) 2003-06-02 2010-05-25 Van Der Weide Daniel Warren Apparatus and method for near-field imaging of tissue
US7298869B1 (en) 2003-07-21 2007-11-20 Abernathy Donald A Multispectral data acquisition system and method
IL164030A0 (en) 2003-09-12 2005-12-18 Revital Pery Shechter Photoacoustic analyzer of a region of interest in a human body
US20050107694A1 (en) * 2003-11-17 2005-05-19 Jansen Floribertus H. Method and system for ultrasonic tagging of fluorescence
US20050154308A1 (en) 2003-12-30 2005-07-14 Liposonix, Inc. Disposable transducer seal
JP4643153B2 (ja) 2004-02-06 2011-03-02 株式会社東芝 非侵襲生体情報映像装置
US7525661B2 (en) 2004-02-17 2009-04-28 Andreas Mandelis Laser photo-thermo-acoustic (PTA) frequency swept heterodyned lock-in depth profilometry imaging system
US7804075B2 (en) 2004-03-11 2010-09-28 The General Hospital Corporation Method and system for tomographic imaging using fluorescent proteins
WO2005107592A1 (ja) 2004-05-06 2005-11-17 Nippon Telegraph And Telephone Corporation 成分濃度測定装置及び成分濃度測定装置制御方法
US7510555B2 (en) 2004-05-07 2009-03-31 Therm Med, Llc Enhanced systems and methods for RF-induced hyperthermia
US7471975B2 (en) * 2004-09-22 2008-12-30 The Research Foundation Of State University Of New York Optical tensor imaging
US20060084861A1 (en) 2004-10-18 2006-04-20 Topspin Medical (Isreal) Ltd. Magnet and coil configurations for MRI probes
WO2006061829A1 (en) * 2004-12-06 2006-06-15 Glucon Inc. Photoacoustic intravascular probe
WO2006063246A1 (en) * 2004-12-08 2006-06-15 The General Hospital Corporation System and method for normalized fluorescence or bioluminescence imaging
IL166408A0 (en) 2005-01-20 2006-01-15 Ultraview Ltd Combined 2d pulse-echo ultrasound and optoacousticsignal for glaucoma treatment
US20060184042A1 (en) 2005-01-22 2006-08-17 The Texas A&M University System Method, system and apparatus for dark-field reflection-mode photoacoustic tomography
WO2006125452A1 (en) 2005-05-23 2006-11-30 Universite De Geneve Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
DE102005030151B3 (de) 2005-06-28 2006-11-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Photoakustischer Freifelddetektor
US20070015992A1 (en) 2005-06-30 2007-01-18 General Electric Company System and method for optoacoustic imaging
US7247842B1 (en) 2005-07-12 2007-07-24 California Institute Of Technology Method and system for scanning apertureless fluorescence mircroscope
US8041409B2 (en) 2005-09-08 2011-10-18 Carestream Health, Inc. Method and apparatus for multi-modal imaging
US8660631B2 (en) 2005-09-08 2014-02-25 Bruker Biospin Corporation Torsional support apparatus and method for craniocaudal rotation of animals
WO2007058895A2 (en) 2005-11-11 2007-05-24 Visualsonics Inc. Overlay image contrast enhancement
ATE500778T1 (de) 2005-12-22 2011-03-15 Visen Medical Inc Kombiniertes röntgen- und optisches tomographie- bildgebungssystem
US20090054763A1 (en) 2006-01-19 2009-02-26 The Regents Of The University Of Michigan System and method for spectroscopic photoacoustic tomography
WO2007084771A2 (en) 2006-01-20 2007-07-26 Seno Medical Instruments, Inc. Quantitative optoacoustic tomography with enhanced contrast
JP2007307007A (ja) 2006-05-17 2007-11-29 Hamamatsu Kagaku Gijutsu Kenkyu Shinkokai 光音響効果を用いたカテーテルシステム
WO2008018082A2 (en) 2006-08-10 2008-02-14 Technion - Research & Development Foundation Ltd Plasmon resonance bolometer for radiation detection
US7741045B2 (en) 2006-11-16 2010-06-22 General Electric Company Sequential analysis of biological samples
WO2008067438A2 (en) 2006-11-29 2008-06-05 The Regents Of University Of Michigan System and method for photoacoustic guided diffuse optical imaging
US20080173093A1 (en) 2007-01-18 2008-07-24 The Regents Of The University Of Michigan System and method for photoacoustic tomography of joints
WO2008101019A2 (en) 2007-02-13 2008-08-21 Board Of Regents, The University Of Texas System Molecular specific photoacoustic imaging
US20080221647A1 (en) * 2007-02-23 2008-09-11 The Regents Of The University Of Michigan System and method for monitoring photodynamic therapy
US20080228073A1 (en) 2007-03-12 2008-09-18 Silverman Ronald H System and method for optoacoustic imaging of peripheral tissues
US8314406B2 (en) 2007-04-06 2012-11-20 The General Hospital Corporation Systems and methods for optical imaging using early arriving photons
US7894885B2 (en) 2007-05-02 2011-02-22 Biosense Webster, Inc. Coherent signal rejection in ECG
WO2009011884A1 (en) 2007-07-16 2009-01-22 Arnold Stephen C Acoustic imaging probe incorporating photoacoustic excitation
US20090058746A1 (en) 2007-08-31 2009-03-05 Harris Corporation Evanescent wave-coupled frequency selective surface
US8492734B2 (en) 2007-10-19 2013-07-23 Visen Medical, Inc. Imaging systems featuring waveguiding compensation
CA2708675C (en) 2007-12-12 2016-07-19 Jeffrey J. L. Carson Three-dimensional photoacoustic imager and methods for calibrating an imager
US9332942B2 (en) 2008-01-28 2016-05-10 The General Hospital Corporation Systems, processes and computer-accessible medium for providing hybrid flourescence and optical coherence tomography imaging
EP2110076A1 (en) 2008-02-19 2009-10-21 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Method and device for near-field dual-wave modality imaging
JP5749164B2 (ja) 2008-07-25 2015-07-15 ヘルムホルツ・ツェントルム・ミュンヒェン・ドイチェス・フォルシュンクスツェントルム・フューア・ゲズントハイト・ウント・ウムベルト（ゲーエムベーハー）Ｈｅｌｍｈｏｌｔｚ Ｚｅｎｔｒｕｍ ＭｕｅｎｃｈｅｎＤｅｕｔｓｃｈｅｓ Ｆｏｒｓｃｈｕｎｇｓｚｅｎｔｒｕｍ ｆｕｅｒ Ｇｅｓｕｎｄｈｅｉｔ ｕｎｄ Ｕｍｗｅｌｔ （ＧｍｂＨ） 組織バイオマーカーの定量的多重スペクトル光音響トモグラフィ
CN102223840B (zh) 2008-09-10 2015-03-18 安德拉有限公司 光声成像设备
US9528966B2 (en) 2008-10-23 2016-12-27 Washington University Reflection-mode photoacoustic tomography using a flexibly-supported cantilever beam
JP2010125260A (ja) 2008-12-01 2010-06-10 Canon Inc 生体検査装置
WO2010086861A1 (en) 2009-01-29 2010-08-05 Noel Axelrod Multimodal depth-resolving endoscope
US9271654B2 (en) 2009-06-29 2016-03-01 Helmholtz Zentrum Munchen Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) Thermoacoustic imaging with quantitative extraction of absorption map
JP5574674B2 (ja) 2009-11-12 2014-08-20 キヤノン株式会社 音響波測定装置
EP2332614A1 (en) 2009-12-10 2011-06-15 Theraclion SAS Ultrasound treatment device
US10786158B2 (en) 2009-12-10 2020-09-29 The Board Of Regents Of The University Of Texas System Optoacoustic / photoacoustic / acoustic imaging system using probe beam deflection
EP2359745A1 (en) 2010-02-12 2011-08-24 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Method and device for multi-spectral photonic imaging
JP5448918B2 (ja) 2010-02-24 2014-03-19 キヤノン株式会社 生体情報処理装置
JP5479173B2 (ja) 2010-03-17 2014-04-23 キヤノン株式会社 情報処理装置および情報処理方法
US20130190591A1 (en) 2010-04-30 2013-07-25 Desmond Hirson Photoacoustic transducer and imaging system
US8930145B2 (en) 2010-07-28 2015-01-06 Covidien Lp Light focusing continuous wave photoacoustic spectroscopy and its applications to patient monitoring
WO2012103903A1 (en) 2011-02-04 2012-08-09 Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Ultrasound detector and detecting device for optoacoustic or thermoacoustic imaging
JP5744557B2 (ja) 2011-02-10 2015-07-08 キヤノン株式会社 音響波取得装置
JP5939786B2 (ja) 2011-02-10 2016-06-22 キヤノン株式会社 音響波取得装置
JP5469113B2 (ja) 2011-02-24 2014-04-09 富士フイルム株式会社 光音響分析用プローブユニットおよび光音響分析装置
JP5704998B2 (ja) 2011-04-06 2015-04-22 キヤノン株式会社 光音響装置およびその制御方法
JP5762118B2 (ja) 2011-05-02 2015-08-12 キヤノン株式会社 光照射装置およびその制御方法、ならびに被検体情報取得装置
US9390522B2 (en) 2011-11-18 2016-07-12 Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt (Gmbh) System for creating a tomographic object image based on multiple imaging modalities
US20150366458A1 (en) 2012-05-07 2015-12-24 Helmholtz Zentrum Munchen Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) Apparatus and method for frequency-domain thermo-acoustic tomographic imaging
JP5969701B2 (ja) 2012-06-11 2016-08-17 ヘルムホルツ ツェントルム ミュンヘン ドイチェス フォルシュンクスツェントルム フュア ゲスントハイト ウント ウンベルト ゲゼルシャフト ミット ベシュレンクテル ハフツング 対象物を撮像するための撮像システムと方法
EP2695893A1 (en) 2012-08-09 2014-02-12 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH Novel far red fluorescent protein
US10076248B2 (en) 2012-10-22 2018-09-18 The General Hospital Corporation Hybrid catheter system
EP2742854B1 (en) 2012-12-11 2021-03-10 iThera Medical GmbH Handheld device and method for tomographic optoacoustic imaging of an object
EP2742853B1 (en) 2012-12-11 2022-03-23 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH Handheld device and method for volumetric real-time optoacoustic imaging of an object
EP2754388B1 (en) 2013-01-15 2020-09-09 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH System and method for quality-enhanced high-rate optoacoustic imaging of an object

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