CN102100730A - Traditional Chinese medicine for improving poultry immunity - Google Patents
Traditional Chinese medicine for improving poultry immunity Download PDFInfo
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- CN102100730A CN102100730A CN 201110028631 CN201110028631A CN102100730A CN 102100730 A CN102100730 A CN 102100730A CN 201110028631 CN201110028631 CN 201110028631 CN 201110028631 A CN201110028631 A CN 201110028631A CN 102100730 A CN102100730 A CN 102100730A
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Abstract
The invention discloses a traditional Chinese medicine for improving poultry immunity, which is prepared from the following raw material medicines in part by weight: 200 to 600 parts of astragalus, 100 to 400 parts of fried largehead atractylodes rhizome, 100 to 200 parts of divaricate saposhnikovia root and 100 to 300 parts of epimedium herb. The components are prepared into powder, ultramicro powder (superfine powder), oral liquid, granules, fluid extracts, extracts and medicinal preparations for clinical application. The preparation has effects of tonifying qi, consolidating superficial resistance, improving yang, and improving immunity and antibody titer and poultry uniformity after the poultry is immunized by vaccines. The preparation is used for health care of weak, low-uniformity poultry groups with frequent diseases, and is used for improving disease resistance and improving vaccine immunity effect. The content of the contained harmful substances, such as lead (pb) and arsenic (As), does not exceed national specified standard.
Description
Technical field
The present invention relates to a kind of birds and use Chinese medicine, relate in particular to a kind of be used to improve the antibody titer behind poultry immunity power and the vaccine immunity and the Chinese medicine of poultry regularity.
Background technology
At present, at poultry farming, for prevent disease and treatment disease, generally give a large amount of antibiotic, hormone and other antibacterials of poultry feeding, because antibiotic and hormone retain in poultry body for a long time in a large number, not only meat greatly reduces, and harmful material is residual too high in meat products and the egg products simultaneously, is threatening human edible safety.According to the study, eat too much and contain chemohormonal food, can cause child's sexual precosity, concerning the adult, can influence even destroy human organs such as liver, kidney, but also can destroy the beneficial bacteria in the intestinal, What is more, may cause cancer.Because feeding time is not enough, thereby cause the deficiency of nutrition, the former poultry egg that should contain 40 multiple nutrients materials, owing to used chemical hormone, not only nutrition is not up to standard, and harmful substance exceeds standard, and more seriously the shortage of nutrition can make the people suffer from rickets.The production of chemical feed has also caused severe contamination to environment, and China relevant department has begun to formulate higher meat products standard.Ban use of chemical addition agent, the development green cultivation had become the trend of aquaculture development already.In order to prevent poultry infection immunity inhibition virus or to treat infection immunity inhibition virus, method commonly used is to use vaccine, but immune vaccine only plays the effect of this kind of prevention disease, does not reach the effect of treatment, and antibody titer rising speed is slow, the antibody weak point of holding time; Also need to use a large amount of antibiotic and hormone in order to treat disease.
Summary of the invention
Purpose of the present invention aims to provide a kind of poultry immunity power that is used to strengthen, the antibody titer behind the raising vaccine immunity and the Chinese medicine that is used to strengthen poultry immunity power of poultry regularity.
For finishing above-mentioned purpose, technical solution of the present invention is: a kind of Chinese medicine that is used to strengthen poultry immunity power, it is made by following material medicine, by weight calculating the Radix Astragali of 200-600, the Rhizoma Atractylodis Macrocephalae of 100-400 (stir-fry), the Radix Saposhnikoviae of 100-200 and the Herba Epimedii of 100-300.
The above-mentioned described manufacture method that is used to strengthen the Chinese medicine of poultry immunity power can be pulverized the Radix Astragali, the Rhizoma Atractylodis Macrocephalae (stir-fry) and the Radix Saposhnikoviae of above-mentioned described amount and be mixed and made into powder, superfine powder (impalpable powder) and granule; Also can make oral liquid, fluid extract and extractum by the water extraction.Also can be made into can be for the pharmaceutical preparation of clinical practice.The usage and the consumption of said preparation are: the 2g raw medicinal herbs is made corresponding preparations and can be converted water 1L and drink for fowl, and logotype 3-5 days is a course of treatment.With the oral liquid is example, can be made into the oral liquid that 1ml contains the 1g raw medicinal herbs, mixes drink with water, and the oral liquid of every 2ml and 1L water mix drink, logotype 3～5 days.When being used to improve immune effect of vaccine, can use the administration of drinking water respectively with vaccine simultaneously.
The present invention has QI invigorating, consolidating superficial resistance, yang invigorating, the antibody titer behind raising immunity and the vaccine immunity and the effect of poultry regularity.Be used for the chicken group's weak, that regularity is poor, disease takes place frequently health care, disease resistance enhancemen increases immune effect of vaccine.Through check, poisonous and harmful substance lead of the present invention (pb), arsenic (As) content all do not surpass the GB required standard.
Its clinical trial is as follows:
Experiment one, oral liquid that the present invention is made are to the influence of the brown laying hen IBD of Yi Sha immune effect of vaccine.
1 test material and method
1.1 test grouping and processing
Strong young 450 of the brown laying hen of 1 age in days Yi Sha is divided into 3 groups, 150 every group by the random packet test design method.Experimental group (I group) carries out the IBD vaccine immunity as requested, and since the administration of drinking water in the 7th day (adding oral liquid 2.0mL of the present invention in every liter of drinking-water), 3 weeks of administration; Any medicine is not added in negative control group (II group) immunity; The not immune any medicine (III group) that do not add of jack to jack adapter matched group.Test group and matched group are all taked to raise in cages, free choice feeding, identical conventional feeding and management condition, 9 weeks of experimental period.
1.2IBD antibody horizontal is measured
Each for examination chickling in 14,28 days with the immunity of IBD vaccine collunarium eye dripping.And respectively get 10 blood samplings respectively at 21,35,49,63 days, and conventional separation of serum suppresses (HI) test method determination HI antibody titer with Microhemagglutination, and indirect ELISA method detects IBD antibody.
2. result and analysis
2.1 the oral liquid that the present invention makes to the IBD vaccine immunity after the influence of antibody
The results are shown in Table 1.It is close that 21 ages in days are respectively organized bursal antibody, and difference is remarkable (P＞0.05) not; 35 age in days I group antibody horizontal is significantly higher than II and III group, significant difference (P＜0.05); 49 ages in days, 63 age in days I group antibody horizontal are significantly higher than II and III group, and difference is (P＜0.01) extremely significantly.Show that the oral liquid that the present invention makes drinks the immune effect that can significantly strengthen chicken IBD vaccine by 0.2% concentration, can impel the antibody titer of bursal disease virus to raise rapidly, prolong antibody and hold time.
Table 1ELISA method detects the antibody result (nlog10) who respectively organizes bursal disease virus
2.2 influence to the chicken growth promoter
The results are shown in Table 2.21 ages in days, it is close that each organizes average weight, and difference is remarkable (P＞0.05) not; 35,49 ages in days, I and II group average weight are significantly higher than III group, significant difference (P＜0.05); 63 ages in days, I group average weight is significantly higher than II group (P＜0.05), and the utmost point is significantly higher than III group (P＜0.01); I and the average daily gain of II group are significantly higher than III group, significant difference (P＜0.05).Show that this invention oral liquid drinks the growth promoter that can significantly promote chicken by 0.20% and 0.4% concentration.
The influence of table 2 pair test chickling fertility performance
3. conclusion
Test shows, adds oral liquid of the present invention in the drinking-water and can promote chick growth to grow, and significantly strengthens the immune effect of chicken IBD vaccine, impels chickling to produce antibody rapidly, prolongs antibody and holds time.
Experiment two, oral liquid of the present invention are to the influence of parts in Beijing opera spoken in Beijing dialect laying chickling ND immune effect of vaccine
1. materials and methods
1.1 laboratory animal grouping
450 raising to 7 ages in days of 1 age in days parts in Beijing opera spoken in Beijing dialect cock are equally divided into the administration group with chickling: every premium on currency administration 2mL at random for examination; Blank group I: not administration of immunity group; Blank II: not immune not administration group, 150 every group.
1.2 test method
The mensuration of antibody horizontal: adopt Microhemagglutination (HA) and blood clotting to suppress (HI) test and detect newcastle epidemic disease antibody.
2. result
The blood serum sample of 5 collections is measured newcastle epidemic disease antibody tire, each newcastle epidemic disease antibody of organizing different all ages the results are shown in following table.
Each organizes the antibody horizontal in each age in week
3. conclusion
This laboratory observation oral liquid of the present invention variation that chicken ND vaccine immunity parts in Beijing opera spoken in Beijing dialect laying chickling newcastle epidemic disease antibody is tired.The result proves, oral liquid of the present invention is for the effect of being significantly improved of tiring of chicken ND vaccine immunity parts in Beijing opera spoken in Beijing dialect laying chickling newcastle epidemic disease antibody.
The specific embodiment
Below in conjunction with specific embodiment the present invention is described further.
Embodiment 1: present embodiment is made by following raw materials according: by weight calculating the Radix Astragali 600, the Rhizoma Atractylodis Macrocephalae (stir-fry) 100, Radix Saposhnikoviae 100, Herba Epimedii 200.Above component is made powder, superfine powder (impalpable powder), oral liquid, granule, fluid extract, extractum and any pharmaceutical preparation for clinical practice according to aforementioned proportion.
Embodiment 2: present embodiment is made by following raw materials according: the Radix Astragali 500, the Rhizoma Atractylodis Macrocephalae (stir-fry) 200, Radix Saposhnikoviae 150, Herba Epimedii 150.Above component is made powder, superfine powder (impalpable powder), oral liquid, granule, fluid extract, extractum and any pharmaceutical preparation for clinical practice according to aforementioned proportion.
Embodiment 3: present embodiment is made by following raw materials according: the Radix Astragali 400, the Rhizoma Atractylodis Macrocephalae (stir-fry) 300, Radix Saposhnikoviae 200, Herba Epimedii 100.Above component is made powder, superfine powder (impalpable powder), oral liquid, granule, fluid extract, extractum and any pharmaceutical preparation for clinical practice according to aforementioned proportion.
Embodiment 4: present embodiment is made by following raw materials according: the Radix Astragali 300, the Rhizoma Atractylodis Macrocephalae (stir-fry) 250, Radix Saposhnikoviae 125, Herba Epimedii 300.Above component is made powder, superfine powder (impalpable powder), oral liquid, granule, fluid extract, extractum and any pharmaceutical preparation for clinical practice according to aforementioned proportion.
Embodiment 5: present embodiment is made by following raw materials according: the Radix Astragali 200, the Rhizoma Atractylodis Macrocephalae (stir-fry) 400, Radix Saposhnikoviae 175, Herba Epimedii 250.Above component is made powder, superfine powder (impalpable powder), oral liquid, granule, fluid extract, extractum and any pharmaceutical preparation for clinical practice according to aforementioned proportion.
Embodiment 6: present embodiment is made by following raw materials according: the Radix Astragali 350, the Rhizoma Atractylodis Macrocephalae (stir-fry) 150, Radix Saposhnikoviae 140, Herba Epimedii 175.Above component is made powder, superfine powder (impalpable powder), oral liquid, granule, fluid extract, extractum and any pharmaceutical preparation for clinical practice according to aforementioned proportion.
Embodiment 7: present embodiment is made by following raw materials according: the Radix Astragali 450, the Rhizoma Atractylodis Macrocephalae (stir-fry) 350, Radix Saposhnikoviae 190, Herba Epimedii 225.Above component is made powder, superfine powder (impalpable powder), oral liquid, granule, fluid extract, extractum and any pharmaceutical preparation for clinical practice according to aforementioned proportion.
Claims (9)
1. Chinese medicine that is used to strengthen poultry immunity power, it is characterized in that: it is made by following material medicine, by weight calculating the Radix Astragali of 200-600, the Rhizoma Atractylodis Macrocephalae of 100-400 (stir-fry), the Radix Saposhnikoviae of 100-200 and the Herba Epimedii of 100-300.
2. the Chinese medicine that is used to strengthen poultry immunity power according to claim 1 is characterized in that: it is made by following material medicine, by weight calculating the Radix Astragali 600, the Rhizoma Atractylodis Macrocephalae (stir-fry) 100, Radix Saposhnikoviae 100, Herba Epimedii 200.
3. the Chinese medicine preparation that is used to strengthen poultry immunity power according to claim 1 is characterized in that: it is made by following material medicine, by weight calculating the Radix Astragali 500, the Rhizoma Atractylodis Macrocephalae (stir-fry) 200, Radix Saposhnikoviae 150, Herba Epimedii 150.
4. the Chinese medicine preparation that is used to strengthen poultry immunity power according to claim 1 is characterized in that: it is made by following material medicine, by weight calculating the Radix Astragali 400, the Rhizoma Atractylodis Macrocephalae (stir-fry) 300, Radix Saposhnikoviae 200, Herba Epimedii 100.
5. the Chinese medicine preparation that is used to strengthen poultry immunity power according to claim 1 is characterized in that: it is made by following material medicine, by weight calculating the Radix Astragali 300, the Rhizoma Atractylodis Macrocephalae (stir-fry) 250, Radix Saposhnikoviae 125, Herba Epimedii 300.
6. the Chinese medicine preparation that is used to strengthen poultry immunity power according to claim 1 is characterized in that: it is made by following material medicine, by weight calculating the Radix Astragali 200, the Rhizoma Atractylodis Macrocephalae (stir-fry) 400, Radix Saposhnikoviae 175, Herba Epimedii 250.
7. the Chinese medicine preparation that is used to strengthen poultry immunity power according to claim 1 is characterized in that: it is made by following material medicine, by weight calculating the Radix Astragali 350, the Rhizoma Atractylodis Macrocephalae (stir-fry) 150, Radix Saposhnikoviae 140, Herba Epimedii 175.
8. the Chinese medicine preparation that is used to strengthen poultry immunity power according to claim 1 is characterized in that: it is made by following material medicine, by weight calculating the Radix Astragali 450, the Rhizoma Atractylodis Macrocephalae (stir-fry) 350, Radix Saposhnikoviae 190, Herba Epimedii 225.
9. each described manufacture method that is used to strengthen the Chinese medicine preparation of poultry immunity power in the claim 1 to 8, it is characterized in that: it can be pulverized the Radix Astragali, the Rhizoma Atractylodis Macrocephalae (stir-fry) and the Radix Saposhnikoviae of above-mentioned described amount be mixed and made into powder, superfine powder (impalpable powder) and granule; Also can make oral liquid, fluid extract and extractum by the water extraction.
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| CN2011100286310A CN102100730B (en) | 2011-01-27 | 2011-01-27 | Traditional Chinese medicine for improving poultry immunity |
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| CN2011100286310A CN102100730B (en) | 2011-01-27 | 2011-01-27 | Traditional Chinese medicine for improving poultry immunity |
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| CN102100730A true CN102100730A (en) | 2011-06-22 |
| CN102100730B CN102100730B (en) | 2012-08-15 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860656A (en) * | 2012-12-11 | 2014-06-18 | 洛阳惠中兽药有限公司 | Traditional Chinese medicinal composition, and preparation method and application thereof |
| CN107594094A (en) * | 2017-10-27 | 2018-01-19 | 石开林 | A kind of poultry insect Chinese herbal feed nutritional agents |
| CN108619469A (en) * | 2018-05-11 | 2018-10-09 | 陈庆和 | A kind of immunity of poultry reinforcing agent and preparation method thereof |
-
2011
- 2011-01-27 CN CN2011100286310A patent/CN102100730B/en active Active
Non-Patent Citations (4)
| Title |
|---|
| 《中国优秀硕士学位论文全文数据库 农业科技辑》 20091015 王海龙 玉屏风散对法氏囊病疫苗免疫效果的影响 摘要，正文第10页"2.2中药制剂的制备" 1-9 , 第10期 * |
| 《中国优秀硕士学位论文全文数据库 农业科技辑》 20091015 王海龙 玉屏风散对法氏囊病疫苗免疫效果的影响 摘要，正文第10页"2.2中药制剂的制备" 1-9 , 第10期 2 * |
| 《牡丹江医学院学报》 20001231 张红军，等 玉屏风散的免疫学研究进展 第58页左栏倒数第6-10行 1-9 第21卷, 第4期 * |
| 《牡丹江医学院学报》 20001231 张红军，等 玉屏风散的免疫学研究进展 第58页左栏倒数第6-10行 1-9 第21卷, 第4期 2 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860656A (en) * | 2012-12-11 | 2014-06-18 | 洛阳惠中兽药有限公司 | Traditional Chinese medicinal composition, and preparation method and application thereof |
| CN107594094A (en) * | 2017-10-27 | 2018-01-19 | 石开林 | A kind of poultry insect Chinese herbal feed nutritional agents |
| CN108619469A (en) * | 2018-05-11 | 2018-10-09 | 陈庆和 | A kind of immunity of poultry reinforcing agent and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN102100730B (en) | 2012-08-15 |
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Denomination of invention: Traditional Chinese medicine for enhancing immunity of poultry Effective date of registration: 20210115 Granted publication date: 20120815 Pledgee: China Construction Bank Gaoyang sub branch Pledgor: BAODING JIZHONG PHARMACEUTICAL Co.,Ltd. Registration number: Y2021980000409 |
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