CN102100784A - Animal immunoenhancement taking Echinacea as main component - Google Patents
Animal immunoenhancement taking Echinacea as main component Download PDFInfo
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- CN102100784A CN102100784A CN2009102556887A CN200910255688A CN102100784A CN 102100784 A CN102100784 A CN 102100784A CN 2009102556887 A CN2009102556887 A CN 2009102556887A CN 200910255688 A CN200910255688 A CN 200910255688A CN 102100784 A CN102100784 A CN 102100784A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
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Abstract
The invention discloses an animal immunoenhancement taking Echinacea as the main component. The formula of the animal immunoenhancement comprises the following components in parts by weight: 40-50 parts of Echinacea, 25-35 parts of astragalus mongholicus, 18-22 parts of angelica sinensis and 13-17 parts of dried orange peel. The animal immunoenhancement disclosed by the invention has low cost and a good effect on improving the animal immunologic function, and can improve animal growth performance.
Description
Technical field
The present invention relates to a kind of animal immunity potentiator, the spy be fully a kind of be the animal immunity potentiator of main formula with the Echinacea.
Technical background
The imbalance of the generation of numerous disease and development and body immune system functional defect or function has close getting in touch.The height of body's immunity directly influences health status and the production capacity of animal, thereby influences human life quality.Immunostimulant is to use the material of can enhancing human body immunity replying with antigen individually or simultaneously, and its kind reaches hundreds of, mainly comprises: minerals, natural drug class, chemicals class, microorganism formulation class etc.There is the reduction breeding performonce fo animals in the part chemicals as immunomodulator, causes toxic and side effects and drug residue pollution livestock products such as multiple disease, contaminated environment, numerous drawbacks such as harm humans health.
Medical herbs in the natural drug is the human defending and fighting against diseases material of using the earliest, it also is the feed additive that is employed the earliest, it has safe, toxic and side effects is little, plurality of advantages such as immunoenhancement result is good, in the today of " back to nature is advocated green ", obtained the extensive approval of countries in the world.Echinacea is as the plantation widely at home of a kind of advantitious plant, and its property is sweet, and little hardship is slightly cold; Return lung, spleen, Liver Channel.Wind and heat dispersing, benefiting QI for strengthening the superficies, suppressing the hyperactive liver makes eye bright.Cure mainly affection due to external wind and heat, instability of surface, conjunctival congestion and swelling pain.The foreign study report, Echinacea has the effect of " nourishing bone marrow ", and domestic result of study shows, its benefiting action and the Chinese medicine Rhizoma Atractylodis Macrocephalae or the Radix Astragali are suitable, the effect of " strengthening the body resistance " is therefore also arranged, can grow void and help the weak, improve body specificity and non-specific immunity.But the animal immunity potentiator that with the Echinacea is main formula does not appear in the newspapers.
Summary of the invention
At the deficiencies in the prior art, it is low to the invention provides a kind of cost, can improve the animal immune ability and improve the animal immunity potentiator of its growth performance.
The present invention is for reaching above purpose, be achieved through the following technical solutions: providing a kind of is the animal immunity potentiator of main formula with the Echinacea, and the recipe ingredient of this reinforcing agent is counted by weight: Echinacea 40-50 part, Radix Astragali 25-35 part, Radix Angelicae Sinensis 18-22 part and Pericarpium Citri Reticulatae 13-17 part.
To of the present invention a kind of be that the animal immunity potentiator of main formula carries out following improvement with the Echinacea: the recipe ingredient of this reinforcing agent is counted by weight: 15 parts of 45 parts of Echinaceas, 30 parts of the Radixs Astragali, 20 parts of Radix Angelicae Sinensis and Pericarpium Citri Reticulataes.
Of the present invention is the animal immunity potentiator of main formula with the Echinacea, and what select for use all is common raw material, therefore can control production cost to greatest extent.Main formula Echinacea particularly, already in China's successful introduction, there is sizable cultivated area in domestic a plurality of provinces at present, therefore the raw material problem solves, and result of study shows the Echinacea safety non-toxic, with it is the animal immunity potentiator that raw material is made, and can improve the animal immune function, promotes growth of animal.The veterinary drug or the feed additive of the various dosage forms of moving immunostimulant suitable for making of the present invention are suitable for all kinds of animals such as pig, fowl, dog, cat and take for a long time, can not develop immunity to drugs, and also can partly replace the antibiotic that adds in the feedstuff.
Of the present invention is the animal immunity potentiator of main formula with the Echinacea, to the enhancing of animal immune ability with promote that growth of animal can prove by following test:
1,1 age in days egg cock is 240, is divided into 8 groups at random, 30 every group.Carry out administration according to table 1 scheme respectively since 10 ages in days, continuous use 10 days.13 ages in days are the immunity of Seedling collunarium eye dripping with newcastle IV, and 2 part/only, 24 ages in days begin the above medication of repetition, and 27 ages in days carry out two and exempt from.
Table 1 experiment grouping and processing method
2, evaluating drug effect index: select 10 chicken blood samplings respectively at every group of 10,20,27,35,42 age in days, separation of serum is done newcastle HI antibody titer and is measured, and concrete grammar is seen the diffusing clinical medicine dose screening test that strengthens the chickling immunologic function of Echinacea; Select 10 chicken jugular vein blood samplings respectively at every group of 20,27,35,42 age in days, carry out lymhocyte transformation rate and measure; Data are represented with average ± standard deviation, carry out statistical analysis with SPSS software, and HI antibody titer, fertility performance adopt variance analysis and LSD method multiple comparisons, survival rate x
2Check.
3, result of the test: see Table 2, table 3
Table 2 newcastle HI antibody titer (log2)
By table 2 as seen, newcastle HI antibody titer difference not significantly (p＞0.05) between each group before the immunity; The antibody titer that 20 ages in days (immunity back 1 week) are the 4th, 5 group and the 6th group of difference is remarkable (p＞0.05) not, is significantly higher than 1,2,7,8 group (p＜0.05); The the 3rd, 4 group of 27 age in days (immunity 2 weeks of back) and the 5th, 6 group differences are remarkable (p＞0.05) not, is significantly higher than 1,2,7,8 group (p＜0.05); The the 3rd, 4 group and the 5th, 6 group difference of 35 ages in days (immunity 3 weeks of back) is remarkable (p＞0.05) not, is significantly higher than all the other each groups (p＜0.05); The the 3rd, 4 group and the 5th, 6 group difference of 42 ages in days (immunity 4 weeks of back) is remarkable (p＞0.05) not, is significantly higher than all the other each groups (p＜0.05).Above result shows that the 3rd, 4 group antibody titer is higher, promptly adopt 0.15%, 0.3% concentration take Echinacea loose better to improving chicken antibody titre effect, and 0.15% and 0.3% differences nonsignificance.
Table 3 chicken lymphopoiesis transforms and changes (OD
570)
Result of the test shows, in the OD value of 20 ages in days (immunity 1 week of back) the 3rd, group and the 2nd, 4,6 group of difference not remarkable (p＞0.05), the 1st, 5,7 group of significant difference is lower than the 6th group (p＜0.05); During 27 ages in days, the 3rd, 4,5 group with the 6th group of difference not significantly (p＞0.05), the 1st, 7 group significantly is lower than the 6th group (p＜0.05); During 35 ages in days, the 3rd group is significantly higher than all the other each group (p＜0.05), 4,5 groups with the 6th group of difference not significantly (p＞0.05); During 42 ages in days, 3,4,5 groups of difference is significantly (p＞0.05) not, and the 3rd group is significantly higher than the 6th group (p＜0.05), and 1,2,7 group significantly is lower than 6 groups (p＜0.05).Above result shows, Echinacea is mixed diseases caused by retention of fluid usefulness with 0.15% and 0.3% concentration, and better to improving chicken peripheral blood lymphocyte propagation conversion ratio effect, what wherein effect was best is the 3rd group, and promptly mixing diseases caused by retention of fluid concentration is 0.15%.
Whole test is in the phase, and each organizes chicken does not all have death condition.
The specific embodiment
Embodiment 1, a kind of be the animal immunity potentiator of main formula with the Echinacea, take by weighing raw material (kg) by following proportioning: 15 parts of 45 parts of Echinaceas, 30 parts of the Radixs Astragali, 20 parts of Radix Angelicae Sinensis and Pericarpium Citri Reticulataes.
Above-mentioned raw materials is pulverized proportionally mixing.
Embodiment 2, a kind of be the animal immunity potentiator of main formula with the Echinacea, take by weighing raw material (kg) by following proportioning: 15 parts of 40 parts of Echinaceas, 25 parts of the Radixs Astragali, 20 parts of Radix Angelicae Sinensis and Pericarpium Citri Reticulataes.
Above-mentioned raw materials is pulverized proportionally mixing.
Embodiment 3, a kind of be the animal immunity potentiator of main formula with the Echinacea, take by weighing raw material (kg) by following proportioning: 15 parts of 35 parts of Echinaceas, 25 parts of the Radixs Astragali, 22 parts of Radix Angelicae Sinensis and Pericarpium Citri Reticulataes.
Above-mentioned raw materials is pulverized proportionally mixing.
Claims (2)
1. one kind is the animal immunity potentiator of main formula with the Echinacea, it is characterized in that the recipe ingredient of this reinforcing agent is counted by weight: Echinacea 40-50 part, Radix Astragali 25-35 part, Radix Angelicae Sinensis 18-22 part and Pericarpium Citri Reticulatae 13-17 part.
2. according to claim 1 a kind of be the animal immunity potentiator of main formula with the Echinacea, it is characterized in that the recipe ingredient of this reinforcing agent is counted by weight: 15 parts of 45 parts of Echinaceas, 30 parts of the Radixs Astragali, 20 parts of Radix Angelicae Sinensis and Pericarpium Citri Reticulataes.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009102556887A CN102100784A (en) | 2009-12-16 | 2009-12-16 | Animal immunoenhancement taking Echinacea as main component |
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| CN2009102556887A CN102100784A (en) | 2009-12-16 | 2009-12-16 | Animal immunoenhancement taking Echinacea as main component |
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| CN102100784A true CN102100784A (en) | 2011-06-22 |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429122A (en) * | 2011-11-18 | 2012-05-02 | 青岛农业大学 | Immunity-improving vegetable feed additive for sheep |
| CN102919521A (en) * | 2012-11-02 | 2013-02-13 | 北京大北农科技集团股份有限公司 | Vegetable feed additives for improving meat quality, pre-mix feed and formulated feed |
| CN103549134A (en) * | 2013-11-05 | 2014-02-05 | 安徽科技学院 | Broiler chicken feed additive without antibiotics |
| CN103549150A (en) * | 2013-11-05 | 2014-02-05 | 安徽科技学院 | Compound feed additive for green broiler chickens |
| CN104472880A (en) * | 2014-12-12 | 2015-04-01 | 四川乾坤生物科技有限公司 | Veterinary drug composition as well as preparation method and application thereof |
| CN105230970A (en) * | 2015-11-11 | 2016-01-13 | 郑州后羿制药有限公司 | Feed additive for poultry and preparation method of feed additive |
| CN107319171A (en) * | 2017-07-03 | 2017-11-07 | 石家庄江山动物药业有限公司 | It is a kind of to strengthen the Chinese herb feed additive of chicken immunity |
| CN108887473A (en) * | 2018-06-07 | 2018-11-27 | 广东鹏汇生物科技有限公司 | A kind of natural plant feed additives and preparation method thereof |
-
2009
- 2009-12-16 CN CN2009102556887A patent/CN102100784A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429122A (en) * | 2011-11-18 | 2012-05-02 | 青岛农业大学 | Immunity-improving vegetable feed additive for sheep |
| CN102429122B (en) * | 2011-11-18 | 2012-11-21 | 青岛农业大学 | Immunity-improving vegetable feed additive for sheep |
| CN102919521A (en) * | 2012-11-02 | 2013-02-13 | 北京大北农科技集团股份有限公司 | Vegetable feed additives for improving meat quality, pre-mix feed and formulated feed |
| CN103549134A (en) * | 2013-11-05 | 2014-02-05 | 安徽科技学院 | Broiler chicken feed additive without antibiotics |
| CN103549150A (en) * | 2013-11-05 | 2014-02-05 | 安徽科技学院 | Compound feed additive for green broiler chickens |
| CN104472880A (en) * | 2014-12-12 | 2015-04-01 | 四川乾坤生物科技有限公司 | Veterinary drug composition as well as preparation method and application thereof |
| CN105230970A (en) * | 2015-11-11 | 2016-01-13 | 郑州后羿制药有限公司 | Feed additive for poultry and preparation method of feed additive |
| CN105230970B (en) * | 2015-11-11 | 2018-11-02 | 河南后羿实业集团有限公司 | A kind of poultry fodder additive and preparation method thereof |
| CN107319171A (en) * | 2017-07-03 | 2017-11-07 | 石家庄江山动物药业有限公司 | It is a kind of to strengthen the Chinese herb feed additive of chicken immunity |
| CN108887473A (en) * | 2018-06-07 | 2018-11-27 | 广东鹏汇生物科技有限公司 | A kind of natural plant feed additives and preparation method thereof |
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Application publication date: 20110622 |