CN102429122B - Immunity-improving vegetable feed additive for sheep - Google Patents
Immunity-improving vegetable feed additive for sheep Download PDFInfo
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- CN102429122B CN102429122B CN 201110369064 CN201110369064A CN102429122B CN 102429122 B CN102429122 B CN 102429122B CN 201110369064 CN201110369064 CN 201110369064 CN 201110369064 A CN201110369064 A CN 201110369064A CN 102429122 B CN102429122 B CN 102429122B
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- rhizoma atractylodis
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- 241001494479 Pecora Species 0.000 title claims abstract description 23
- 239000003674 animal food additive Substances 0.000 title abstract description 11
- 235000013311 vegetables Nutrition 0.000 title abstract 4
- 241000258180 Echinacea <Echinodermata> Species 0.000 claims abstract description 18
- 235000014134 echinacea Nutrition 0.000 claims abstract description 18
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 claims abstract description 13
- 230000036039 immunity Effects 0.000 claims abstract description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 36
- 239000000463 material Substances 0.000 claims description 31
- 239000003814 drug Substances 0.000 claims description 17
- 239000010271 massa medicata fermentata Substances 0.000 claims description 14
- 229940079593 drug Drugs 0.000 claims description 13
- 239000009636 Huang Qi Substances 0.000 claims description 12
- 239000008187 granular material Substances 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 229920001353 Dextrin Polymers 0.000 claims description 10
- 239000004375 Dextrin Substances 0.000 claims description 10
- 229930006000 Sucrose Natural products 0.000 claims description 10
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 10
- 235000019425 dextrin Nutrition 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 10
- 239000005720 sucrose Substances 0.000 claims description 10
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 9
- 229920002472 Starch Polymers 0.000 claims description 9
- 239000008101 lactose Substances 0.000 claims description 9
- 239000008107 starch Substances 0.000 claims description 9
- 235000019698 starch Nutrition 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 8
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 6
- 239000000796 flavoring agent Substances 0.000 claims description 6
- 235000019634 flavors Nutrition 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 238000012856 packing Methods 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 6
- 239000000741 silica gel Substances 0.000 claims description 6
- 229910002027 silica gel Inorganic materials 0.000 claims description 6
- 239000000284 extract Substances 0.000 claims description 5
- 241000196324 Embryophyta Species 0.000 claims description 4
- 241000545442 Radix Species 0.000 claims description 2
- 241000045403 Astragalus propinquus Species 0.000 abstract 1
- 208000035240 Disease Resistance Diseases 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 238000000605 extraction Methods 0.000 description 16
- 238000012360 testing method Methods 0.000 description 10
- 241000283707 Capra Species 0.000 description 8
- 239000002245 particle Substances 0.000 description 8
- 239000000047 product Substances 0.000 description 8
- 230000001737 promoting effect Effects 0.000 description 8
- 238000010992 reflux Methods 0.000 description 8
- 239000008280 blood Substances 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 7
- 230000002567 autonomic effect Effects 0.000 description 6
- 239000000203 mixture Substances 0.000 description 6
- 241001465754 Metazoa Species 0.000 description 5
- 230000006837 decompression Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000000706 filtrate Substances 0.000 description 4
- 235000012054 meals Nutrition 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- 238000004064 recycling Methods 0.000 description 4
- 230000002354 daily effect Effects 0.000 description 3
- 206010059866 Drug resistance Diseases 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 238000009534 blood test Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 239000003651 drinking water Substances 0.000 description 2
- 235000020188 drinking water Nutrition 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000036737 immune function Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 208000031295 Animal disease Diseases 0.000 description 1
- 102000006395 Globulins Human genes 0.000 description 1
- 108010044091 Globulins Proteins 0.000 description 1
- 208000006650 Overbite Diseases 0.000 description 1
- 238000009360 aquaculture Methods 0.000 description 1
- 244000144974 aquaculture Species 0.000 description 1
- 235000021053 average weight gain Nutrition 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 239000003640 drug residue Substances 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 244000144992 flock Species 0.000 description 1
- 239000004459 forage Substances 0.000 description 1
- 244000144980 herd Species 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses an immunity-improving vegetable feed additive for sheep. The vegetable feed additive is prepared from 6-15 parts of Astragalus mongholicus, 6-15 parts of stir-fried medicated leaven, 6-15 parts of stir-fried malt, 4-10 parts of Rhizoma atractylodis and 4-15 parts of Echinacea and has the functions of improving immunity of sheep and further improving disease resistance of sheep. The vegetable feed additive is safe and efficient.
Description
Technical field
The invention belongs to feed additive field, be specifically related to the development and the application of the vegetalitas promoting immunity feed addictive of a kind of sheep.
Background technology
Along with the development of modern intensive aquaculture, zoogenetic infection various diseases dangerous increasing.In order to prevent Animal diseases; Promote animal growth and improve efficiency of feed utilization; A large amount of antibiotic, chemical synthesis class medicine or hormone medicine are employed as feed addictive; For a long time, a large amount of this type additive on probation, its negative effect manifests day by day, mainly shows: cause the bacterial drug resistance problem to be on the rise; Cause the animal body immunity degradation; Owing to cause the unbalance of the inside and outside flora of body, cause that animal endogenous infection and external source infect; Thereby in animal product and environment, cause the residual human health that makes to receive serious threat.
Autonomic drug is with the advantage common concern of animal health article industry extremely both at home and abroad of its relative natural sex.Chinese herbal granules is on the basis of decoction and powder, to grow up; It has kept decoction to be prone to absorb and act on the characteristics rapid, that bioavilability is high; Avoid the shortcoming that powder is digested and assimilated slowly, dosage is big; But and can mix water and drink also spice and feed, take, transport and store conveniently, receive liking of users.
Therefore, the purpose of this invention is to provide the vegetalitas promoting immunity feed addictive of a kind of sheep, and its methods for making and using same is provided.
Summary of the invention
For realizing above-mentioned purpose; The inventor proposes the vegetalitas promoting immunity feed addictive of a kind of sheep; It is characterized in that this feed addictive is prepared from Radix Astragali 6-15 part, Massa Medicata Fermentata preparata 6-15 part, coloured malt 6-15 part, rhizoma atractylodis 4-10 part and Echinacea 4-15 part and an amount of auxiliary material.
Preferably be prepared from 10 parts of the Radixs Astragali, 8 parts of Massa Medicata Fermentata preparatas, 8 parts of coloured malts, 6 parts of rhizoma atractylodis and 8 parts of Echinaceas and an amount of auxiliary material.
Auxiliary material is selected from one or more in sucrose, dextrin, lactose, starch, the superfine silica gel powder etc.
Above raw material adopts weight portion, calculates the weight with crude drug, can increase or reduce, but constant rate.
The present invention has proposed the preparation method of above-mentioned Chinese herbal granules simultaneously, comprises the steps:
(1) Echinacea is processed the ethanol extracted extract, 4 flavor medicinal materials such as the Radix Astragali, Massa Medicata Fermentata preparata, coloured malt, rhizoma atractylodis are extracted according to the prescription mixed process the water extracted immersing paste powder, the two mixing;
(2) add auxiliary material, mixing; Auxiliary material can be selected one or more in sucrose, dextrin, lactose, starch, the superfine silica gel powder etc.
(3) granulate drying, packing.
The use of this promoting immunity feed addictive: product is added in the sheep feed with 0.2～0.4% according to percentage by weight, can directly feed after stirring, perhaps mix in the drinking-water of sheep, supply sheep freely to drink with 0.1～0.2%.
This prescription has function of spleen and stomach regulating, promoting digestion and removing indigestion, invigorating the spleen with in, the effect of tonifying middle-Jiao and Qi.Through 60 days feeding experiment, can improve the mutton sheep immunologic function, thereby improve its resistance against diseases.
The specific embodiment
With reference to embodiment, content of the present invention is described more specifically below, is should be appreciated that following embodiment is used for explaining content of the present invention, but be not used for limiting scope of the present invention.
Embodiment 1
The raw material prescription is: Radix Astragali 100g, Massa Medicata Fermentata preparata 80g, coloured malt 80g, rhizoma atractylodis 60g, Echinacea 80g; Sucrose and dextrin are an amount of.
Granule preparation: get the Echinacea medicinal material, pulverize and be meal, add 10 times, soak 60min to medicinal material weight 60% ethanol; Refluxing extraction 1 time, extraction time is 2h, filters, the dregs of a decoction add 8 times of 60% ethanol to medicinal material weight again; Refluxing extraction 1 time, extraction time is 1h, filters, and merges filtrating twice; Decompression recycling ethanol, and be concentrated into thick paste, subsequent use.Get 4 flavor medicinal materials such as the Radix Astragali, Massa Medicata Fermentata preparata, coloured malt, rhizoma atractylodis according to the prescription mixed, add and extract twice later Echinacea dregs of a decoction, add 10 times of amount cold water soak 60min, decoct 120min; Filter, medicinal material adds 8 times of water gagings again and decocts 40min, filters merging filtrate; Be concentrated into thick paste, mix with above-mentioned thick paste, add suitable amount of sucrose and dextrin, the ratio of sucrose and dextrin is 1: 1; Mix, the ethanol of adding 90% is an amount of, and mixing adopts wet granulator to granulate; Drying is processed the 400g particle, and packing promptly gets.The crude drug content of gained autonomic drug particle is 1g/g.
Embodiment 2
The raw material prescription is: Radix Astragali 100g, Massa Medicata Fermentata preparata 75g, coloured malt 75g, rhizoma atractylodis 50g, Echinacea 100g; Sucrose and dextrin are an amount of.
Granule preparation: get the Echinacea medicinal material, pulverize and be meal, add 10 times, soak 60min to medicinal material weight 70% ethanol; Refluxing extraction 1 time, extraction time is 2h, filters, the dregs of a decoction add 10 times of 40% ethanol to medicinal material weight again; Refluxing extraction 1 time, extraction time is 1h, filters, and merges filtrating twice; Decompression recycling ethanol, and be concentrated into thick paste, subsequent use.Get 4 flavor medicinal materials such as the Radix Astragali, Massa Medicata Fermentata preparata, coloured malt, rhizoma atractylodis according to the prescription mixed, add 10 times of amount cold water soak 60min, decoct 120min, filter, medicinal material adds 10 times of water gagings again and decocts 40min; Filter, merging filtrate is concentrated into thick paste, mixes with above-mentioned thick paste, adds suitable amount of sucrose and dextrin; The ratio of sucrose and dextrin is 1: 1, mixes, and the ethanol of adding 90% is an amount of, and mixing adopts wet granulator to granulate; Drying is processed the 400g particle, and packing promptly gets.The crude drug content of gained autonomic drug particle is 1g/g.
Embodiment 3
The plant feed additive that embodiment 1 makes (below be stated as " product of the present invention ") is to the influence test of sheep promoting immunity effect:
Selecting 40 6-12 of Yunnan Province's sheep stud monthly age Yunling black goat is subjects, and it is divided into product group of the present invention, the diffusing group of four gentleman, strong diffusing group and blank group, 10 every group.Test is set up preliminary trial period separately and is just being tried the phase.Raise phase 7d in advance, 1/4, the 3-4d of 1-2d interpolation tested number adds 2/3, the 7 day interpolation tested number of 1/3, the 5-6d interpolation tested number of tested number.Preliminary trial period, carries out conventional expelling parasite, weigh and marks overbit the test sheep; Just the examination phase is 60d, during the free sufficient drinking-water of guarantee test flock of sheep, and in time handle pathology and the test sheep of eliminating.
That tests sheep herds supplementary feeding, feeding method, management system and daily arrangement etc. all in strict accordance with " Yunnan Province's sheep stud kind poultry epidemic preventing sanitary and eqpidemic disease are comprehensively put tubulation reason system "; Sheep was herded between 3 in 8 of every mornings to afternoon in test; Carry out supplementary feeding afterwards; Every test sheep supplementary feeding every day fine fodder amount is 0.2kg, and the addition of Chinese herb feed additive is 0.3% of a forage volume.
Pursued an empty stomach respectively at the 30th day, the 60th day that just tries the phase and weigh, calculate average weight gain, the synotus venous blood collection detects hematology and blood biochemical index.
With SPSS17.0 software data are carried out statistical analysis, the significant difference that hematology that employing t check is relatively respectively organized and blood biochemical are learned index.
Table 1 test is divided into groups and processing method
Result of the test:
(1) product of the present invention is to the influence of Yunling black goat routine blood test index
Add Chinese herb feed additive in table 2 daily ration to the influence of Yunling black goat routine blood test index (n=10 of Mean ± SD)
Annotate: colleague right side shoulder indicates lowercase identical table differential different not remarkable (P＞0.05), lowercase different table differential different significantly (P＜0.05), down together.
Visible by table 2, autonomic drug promoting immunity additive of the present invention has certain rising effect to Yunling black goat haemocyte ratio, but compares difference not remarkable (P＞0.05) with control group.
(2) product of the present invention is to the influence of Yunling black goat blood parameters
Add Chinese herb feed additive in table 3 daily ration to the influence of Yunling black goat blood parameters (n=10 of Mean ± SD)
Feeding experiment through 60 days; Visible by table 2; Product of the present invention to the influence of Yunling black goat blood parameters obviously can improve the content of total protein in the blood, globulin, compares significant difference (P＜0.05) with the blank group; Ig-G content there is certain rising effect, compares difference not remarkable (P＞0.05) with control group.
Visible by above result; Product plant feed additive of the present invention has the effect of certain promotion immunologic function to Yunling black goat, and can longerly in feed, add, and is easy to use; Drug residue free; Can not produce problems such as drug resistance and environmental pollution,, improve resistance against diseases and have positive meaning for improving the sheep immunity function.
Embodiment 4
Radix Astragali 60g, Massa Medicata Fermentata preparata 60g, coloured malt 60g, rhizoma atractylodis 40g and Echinacea 40g; Lactose and starch are an amount of.
Granule preparation: get the Echinacea medicinal material, pulverize and be meal, add 10 times, soak 60min to medicinal material weight 60% ethanol; Refluxing extraction 1 time, extraction time is 2h, filters, the dregs of a decoction add 8 times of 60% ethanol to medicinal material weight again; Refluxing extraction 1 time, extraction time is 1h, filters, and merges filtrating twice; Decompression recycling ethanol, and be concentrated into thick paste, subsequent use.Get 4 flavor medicinal materials such as the Radix Astragali, Massa Medicata Fermentata preparata, coloured malt, rhizoma atractylodis according to the prescription mixed, add and extract twice later Echinacea dregs of a decoction, add 10 times of amount cold water soak 60min, decoct 120min, filter; Medicinal material adds 8 times of water gagings again and decocts 40min, filters, and merging filtrate is concentrated into thick paste; Mix with above-mentioned thick paste, add an amount of lactose and starch, the ratio of lactose and starch is 1: 1, mixes; The ethanol of adding 90% is an amount of, and mixing adopts wet granulator to granulate drying; Add an amount of superfine silica gel powder, process the 400g particle, packing promptly gets.The crude drug content of gained autonomic drug particle is 1g/g.
Embodiment 5
The raw material prescription is: Radix Astragali 150g, Massa Medicata Fermentata preparata 150g, coloured malt 150g, rhizoma atractylodis 100g and Echinacea 150g
Granule preparation: get the Echinacea medicinal material, pulverize and be meal, add 10 times, soak 60min to medicinal material weight 60% ethanol; Refluxing extraction 1 time, extraction time is 2h, filters, the dregs of a decoction add 8 times of 60% ethanol to medicinal material weight again; Refluxing extraction 1 time, extraction time is 1h, filters, and merges filtrating twice; Decompression recycling ethanol, and be concentrated into thick paste, subsequent use.Get 4 flavor medicinal materials such as the Radix Astragali, Massa Medicata Fermentata preparata, coloured malt, rhizoma atractylodis according to the prescription mixed, add and extract twice later Echinacea dregs of a decoction, add 10 times of amount cold water soak 60min, decoct 120min, filter; Medicinal material adds 8 times of water gagings again and decocts 40min, filters, and merging filtrate is concentrated into thick paste; Mix with above-mentioned thick paste, add an amount of lactose and starch, the ratio of lactose and starch is 1: 1, mixes; The ethanol of adding 90% is an amount of, and mixing adopts wet granulator to granulate drying; Add an amount of superfine silica gel powder, process the 400g particle, packing promptly gets.The crude drug content of gained autonomic drug particle is 1g/g.
Claims (5)
1. the plant feed addictive of the raise immunity of a sheep is characterized in that: be prepared from following parts by weight of Chinese traditional medicine bulk drug: Radix Astragali 6-15 part, Massa Medicata Fermentata preparata 6-15 part, coloured malt 6-15 part, rhizoma atractylodis 4-10 part and Echinacea 4-15 part.
2. feed addictive according to claim 1 is characterized in that: be prepared from following parts by weight of Chinese traditional medicine bulk drug: 8 parts of 10 parts of the Radixs Astragali, 8 parts of Massa Medicata Fermentata preparatas, 8 parts of coloured malts, 6 parts of rhizoma atractylodis and Echinaceas.
3. feed addictive according to claim 1 is characterized in that: add auxiliary material as required.
4. feed addictive according to claim 3 is characterized in that: said auxiliary material is selected from: one or more in sucrose, dextrin, lactose, starch, the superfine silica gel powder.
5. the preparation method of the described feed addictive of claim 1 is characterized in that: comprise the steps:
(1) Echinacea is processed the ethanol extracted extract, 4 flavor medicinal materials such as the Radix Astragali, Massa Medicata Fermentata preparata, coloured malt, rhizoma atractylodis are extracted according to the prescription mixed process the water extracted immersing paste powder, the two mixing;
(2) add auxiliary material, mixing; Auxiliary material is selected from one or more in sucrose, dextrin, lactose, starch, the superfine silica gel powder;
(3) granulate drying, packing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110369064 CN102429122B (en) | 2011-11-18 | 2011-11-18 | Immunity-improving vegetable feed additive for sheep |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110369064 CN102429122B (en) | 2011-11-18 | 2011-11-18 | Immunity-improving vegetable feed additive for sheep |
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| Publication Number | Publication Date |
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| CN102429122A CN102429122A (en) | 2012-05-02 |
| CN102429122B true CN102429122B (en) | 2012-11-21 |
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| CN 201110369064 Expired - Fee Related CN102429122B (en) | 2011-11-18 | 2011-11-18 | Immunity-improving vegetable feed additive for sheep |
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| CN102885197A (en) * | 2012-08-22 | 2013-01-23 | 句容市富渔水产养殖专业合作社 | Feed for improving immunity of American reeves shads and preparation method for feed |
| CN102919561B (en) * | 2012-11-26 | 2013-10-23 | 洛宁农本畜牧科技开发有限公司 | Feed additive for improving weight increasing velocity and immunity of Funiu white goat and preparation method thereof |
| CN103583864A (en) * | 2013-10-09 | 2014-02-19 | 当涂县西湖家畜养殖场 | Rapid fattening sheep fodder |
| CN103583798A (en) * | 2013-10-09 | 2014-02-19 | 当涂县西湖家畜养殖场 | Sheep fodder capable of reducing morbidity |
| CN104054958A (en) * | 2014-06-16 | 2014-09-24 | 四川国凤中科生物科技有限公司 | Chinese herbal medicine sheep feed additive |
| CN106721032A (en) * | 2017-01-24 | 2017-05-31 | 长治市雄丰清真养殖屠宰有限公司 | A kind of fodder compound of prevention cattle and sheep rickets |
| CN107397048A (en) * | 2017-07-29 | 2017-11-28 | 马鞍山市金农牧业有限公司 | A kind of black goat breeding feed compound additive |
| CN107836577A (en) * | 2017-12-18 | 2018-03-27 | 安徽科技学院 | One kind adult mutton sheep daily ration additive and its application method |
| CN110637931A (en) * | 2019-10-28 | 2020-01-03 | 浙江大学 | Hu sheep fattening and parasite expelling feed additive and application thereof |
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|---|---|---|---|---|
| CN1379993A (en) * | 2001-09-24 | 2002-11-20 | 大连食品集团畜牧公司 | Chinese herbal medicine additive for pig feed |
| CN101856385A (en) * | 2009-04-09 | 2010-10-13 | 张丽环 | Composition containing echinacea extract and preparation method thereof |
| CN102100784A (en) * | 2009-12-16 | 2011-06-22 | 青岛康地恩药业有限公司 | Animal immunoenhancement taking Echinacea as main component |
| CN102100782A (en) * | 2009-12-16 | 2011-06-22 | 青岛康地恩药业有限公司 | Granulated immunopotentiator for pig and poultry and preparation method thereof |
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2011
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1379993A (en) * | 2001-09-24 | 2002-11-20 | 大连食品集团畜牧公司 | Chinese herbal medicine additive for pig feed |
| CN101856385A (en) * | 2009-04-09 | 2010-10-13 | 张丽环 | Composition containing echinacea extract and preparation method thereof |
| CN102100784A (en) * | 2009-12-16 | 2011-06-22 | 青岛康地恩药业有限公司 | Animal immunoenhancement taking Echinacea as main component |
| CN102100782A (en) * | 2009-12-16 | 2011-06-22 | 青岛康地恩药业有限公司 | Granulated immunopotentiator for pig and poultry and preparation method thereof |
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Address after: 266109 Chengyang District, Shandong, Qingdao Patentee after: Qingdao Agricultural University Patentee after: QINGDAO VLAND BIOTECH Inc. Address before: 266109 Chengyang District, Shandong, Qingdao Patentee before: Qingdao Agricultural University Patentee before: QINGDAO KDN PHARMACEUTICAL Co.,Ltd. |
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| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20121121 |