CN102066405B - 用于细胞穿透的超荷电蛋白 - Google Patents

用于细胞穿透的超荷电蛋白 Download PDF

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Publication number
CN102066405B
CN102066405B CN200980123772.1A CN200980123772A CN102066405B CN 102066405 B CN102066405 B CN 102066405B CN 200980123772 A CN200980123772 A CN 200980123772A CN 102066405 B CN102066405 B CN 102066405B
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protein
complex
supercharged
proteins
supercharged protein
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CN102066405A (zh
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大卫·R·刘
布赖恩·R·麦克诺顿
詹姆斯·约瑟夫·克罗尼坎
戴维·B·汤普森
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Harvard University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN200980123772.1A 2008-04-28 2009-04-28 用于细胞穿透的超荷电蛋白 Expired - Fee Related CN102066405B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4837008P 2008-04-28 2008-04-28
US61/048,370 2008-04-28
US10528708P 2008-10-14 2008-10-14
US61/105,287 2008-10-14
PCT/US2009/041984 WO2009134808A2 (en) 2008-04-28 2009-04-28 Supercharged proteins for cell penetration

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CN102066405A CN102066405A (zh) 2011-05-18
CN102066405B true CN102066405B (zh) 2015-09-30

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Country Link
US (1) US20110112040A1 (https=)
EP (1) EP2297182A4 (https=)
JP (2) JP2011523353A (https=)
CN (1) CN102066405B (https=)
AU (1) AU2009243187C1 (https=)
CA (1) CA2725601A1 (https=)
WO (1) WO2009134808A2 (https=)

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JP2011523353A (ja) 2011-08-11
AU2009243187B2 (en) 2015-09-17
AU2009243187B9 (en) 2015-11-12
AU2009243187A1 (en) 2009-11-05
EP2297182A4 (en) 2012-08-15
EP2297182A2 (en) 2011-03-23
CA2725601A1 (en) 2009-11-05
JP2014159484A (ja) 2014-09-04
WO2009134808A2 (en) 2009-11-05
AU2009243187C1 (en) 2015-12-24
WO2009134808A3 (en) 2010-06-10
US20110112040A1 (en) 2011-05-12

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