CN102018654A - Analogous fibroin - Google Patents
Analogous fibroin Download PDFInfo
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- CN102018654A CN102018654A CN2010105126510A CN201010512651A CN102018654A CN 102018654 A CN102018654 A CN 102018654A CN 2010105126510 A CN2010105126510 A CN 2010105126510A CN 201010512651 A CN201010512651 A CN 201010512651A CN 102018654 A CN102018654 A CN 102018654A
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- red algae
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Abstract
The invention belongs to the field of cosmetics, and relates to a skin-care product, namely a Quna analogous fibroin. The analogous fibroin contains the following components of: L-carnosine, lycopene and mixed extract of betel and red alga; the betel extract is obtained by crushing betel and red alga, adding aqueous solution of ethanol for extraction (microwave extraction for 4 to 8 minutes), concentrating the extract and drying the concentrate; and the analogous fibroin contains the following components in part by weight: 0.05 to 0.5 part of L-carnosine, 0.05 to 0.5 part of lycopene and 12 to 16 parts of mixed extract of betel and red alga based on the total weight of the betel and the red alga. The skin-care product provided by the invention can effectively prevent ultraviolet rays from destroying horny cells under the environment of ultraviolet (UV) radiation, supplement skin collagen, repair the destroyed netlike fiber layer, enhance the elasticity of the skin, enhance the vitality and the elasticity of the skin after long-term use and repair the destroyed horny cells.
Description
Technical field
The invention belongs to cosmetic field, relate to a kind of skin care item that contain natural constituent.
Background technology
The rising of the pollution of modern environment and life and work pressure makes people's skin be subjected in various degree damage easily; The radiation of sunlight simultaneously also makes skin aging quicken easily, has to report the driver who drives the taxi car for a long time, and a side skin of accepting sun lights was than opposite side skin aging 7 years, and the office clan on long-term seating window limit also face same problem.Therefore, how to avoid or repair the damage of skin, become the focus of present skin care field research.Although moisturizing, skin care item such as crease-resistant are a feast for the eyes, really can effectively repair damaged skin, slow down aging, still very limited.
Summary of the invention
The objective of the invention is at the deficiencies in the prior art, provide a kind of and can repair impaired horn cell, strengthen skin vigor and elastic skin care item.
Invention is achieved through the following technical solutions above-mentioned purpose.
Invention provides a kind of Quna class fibroin skin care item, contains following composition: the mixed extract of L-carnosine, lycopene, betel leaf and red algae.
Described betel leaf extract is with after betel leaf and the red algae pulverizing, adds ethanol water and extracts (microwave extraction 4-8 minute), and the extracting solution concentrate drying obtains.
Alcoholic acid mass fraction is 60-80% in the described ethanol water; The red algae of betel leaf 1-2 part weight of per 2 parts of weight mixes, and the ethanol-water solution that adds 3-6 part weight extracts.
Each composition weight proportioning constitutes: L-carnosine 0.05-0.5 part, and lycopene 0.05-0.5 part, the mixed extract of betel leaf and red algae is counted 12-16 part with the gross weight of betel leaf and red algae.
These skin care item also contain vitamin B6.The content of vitamin B6 is counted 0.5-1 part with parts by weight.
L-carnosine (β-alanyl-L-histidine) how as food additive, has anti-oxidation characteristics; Be used for cosmetics, have and report that it has the effect that the aging that prevents skin and skin brighten, and can prevent the free radical that produces because of smoking.The present invention mixes the active substance in L-carnosine, lycopene, betel leaf and the red algae; be used for skin keratin cell culture test and body local tuerculoderma; find that it has the function of the shielding angle cell plastid that significantly is better than the L-carnosine, and strengthened the elasticity of human body skin.
Compared with prior art, the present invention has following beneficial effect:
1. skin care item provided by the present invention still can effectively prevent the infringement of ultraviolet to horn cell under the radiating environment of UV, and the character gentleness, can be used as daily skin care item life-time service, can not produce the effect of stimulation of most sunscreen cream.
2. skin care item provided by the present invention replenish the skin collagen protein, repair injured arlt's strata, strengthen skin elasticity, and life-time service can strengthen skin vigor and elasticity, the horn cell of repairing damage.
The specific embodiment
Below further specify technical scheme of the present invention by specific embodiment.
Embodiment 1 emollient cream
The preparation of the mixed extract of betel leaf and red algae:
8 parts of 8 parts of betel leafs, red algae are mixed with 20 parts of ethanol-water solutions (alcoholic acid mass fraction is 90%), and microwave extracting (300W) through vacuum concentration (40 ℃ of temperature), obtained the mixed extract of betel leaf and red algae after 8 minutes.
The preparation of protective skin cream:
List of ingredients (parts by weight)
A. in the mixed extract of above-mentioned betel leaf and red algae, add 0.1 part of L-carnosine, 0.1 part of lycopene is as component A.
B. 2 parts of Arlacel-60s, 0.1 part of imidazolidinyl urea, 1 part of Tween-60
C. the purified cotton seed oil is 7 parts
D. essence is 0.4 part
E. to be supplemented to whole component total amounts be 100 parts for 2 parts of octadecanol, (70%) 3 part of sorbitol solution, deionized water.
Preparation: general, C, E component mix respectively and be heated with stirring to 60 ℃, places emulsator fully emulsified B, C, E component, adds A, D component when temperature is reduced to 40 ℃, static 24h.
Embodiment 2 facial cleaning cream
The preparation of the mixed extract of betel leaf and red algae:
4 parts of 8 parts of betel leafs, red algae are mixed with 15 parts of ethanol-water solutions (alcoholic acid mass fraction is 90%), and microwave extracting (300W) through vacuum concentration (40 ℃ of temperature), obtained the mixed extract of betel leaf and red algae after 6 minutes.
The preparation of facial cleaning cream:
List of ingredients (parts by weight)
A. in the mixed extract of above-mentioned betel leaf and red algae, add 0.3 part of L-carnosine, 0.2 part of lycopene is as component A.
B. 2 parts of octadecanol, 3 parts of squalanes, 1 part of self-emulsifying type glycerol monostearate
It is 100 parts that 20 parts of C.C9-10 alkyl poly glucosides, deionization are supplemented to whole component total amounts.
Preparation: B and C component are heated to 75 ℃ respectively, mix homogenizing.Stirring is cooled to 45 ℃, adds the A component, homogenizing.Cool to room temperature.
Embodiment 3 skin creams
The preparation of the mixed extract of betel leaf and red algae:
6 parts of 10 parts of betel leafs, red algae are mixed with 20 parts of ethanol-water solutions (alcoholic acid mass fraction is 90%), and microwave extracting (300W) through vacuum concentration (40 ℃ of temperature), obtained the mixed extract of betel leaf and red algae after 8 minutes.
The preparation of skin cream:
List of ingredients (parts by weight)
A. in the mixed extract of above-mentioned betel leaf and red algae, add 0.5 part of L-carnosine, 0.5 part of lycopene is as component A.
B. 0.2 part in essence, 3 parts of hexadecanol
C. to be supplemented to whole component total amounts be 100 parts for 4 parts of lanolines, 3 parts of glyceryl monostearates, 2.5 parts of glycerol, 2 parts of isopropyl myristates, 1 part of triethanolamine, 2 parts of stearic acid, 0.2 part of methyl hydroxybenzoate, deionization.
Preparation: C is heated to 75 ℃ makes its dissolving, carry out emulsifying, when temperature is reduced to 45 ℃, add A, B, mixing.
Embodiment 4 surfactant
The preparation of the mixed extract of betel leaf and red algae:
6 parts of 8 parts of betel leafs, red algae are mixed with 20 parts of ethanol-water solutions (alcoholic acid mass fraction is 90%), and microwave extracting (300W) through vacuum concentration (40 ℃ of temperature), obtained the mixed extract of betel leaf and red algae after 8 minutes.
The preparation of surfactant:
List of ingredients (parts by weight)
A. in the mixed extract of above-mentioned betel leaf and red algae, add 0.05 part of L-carnosine, 0.3 part of lycopene is as component A.
B. to be supplemented to whole component total amounts be 100 parts for stearic acid 3%, emulsifying agent 3%, deionization.
Preparation: with B component even matter under 75 ℃, be cooled to 50 ℃ and add the A components, stir.
Embodiment 5 common surfactant
The preparation of common moisture retention water:
Lack the component A in batching, other are with embodiment 4.
Embodiment 6L-carnosine surfactant
With embodiment 4, but component A wherein is: 5 parts of L-carnosines.
Embodiment 7
Compositions is to the protection test of ultraviolet injury keratinocyte:
Cell is handled:
The cell that is opposite in the phosphate buffer with desk-top ultra-vioket radiation instrument shines, and quantitative with the survey meter of 285nmUVB.Behind the ultraviolet radiation, discard covering liquid PBS, add people's serum-free 1640 culture medium to the HaCaT cell, the HaCaT cell in 96 orifice plates is accepted 80mJ/cm
2The UVB irradiation, and continue to cultivate 72h.
The HaCaT cell of 96 well culture plates is divided into 3 groups.Group 1: normal control group (not adding any material); Group 2: compositions group (adding the component A of embodiment 1); Group 3:L-carnosine group (adding the component A of embodiment 6).Every group 3 multiple holes.
After irradiation finished, collecting cell and culture fluid detected.
Detect:
With common blood cell counting plate counting cells;
Detect cytoactive with MTT spare method: behind cell irradiation UV24h in 96 orifice plates, adding 20 μ l concentration in per 100 culture medium is the MMT of 5kg/ml, hatch 4h, supernatant discarded, every hole adds people's dimethyl sulfoxide (DMSO) 100ml, the 15min that vibrates under the room temperature measures the absorbance value in each hole with wavelength 490nm wavelength.
Experimental result is as shown in table 1:
Cell quantity rate of descent under table 1 irradiation under ultraviolet ray and MTT spare method detect the light absorption value result
| ? | Group 1 | Group 2 | Group 3 |
| The cell quantity rate of descent | 75％? | 4％? | 70％? |
| The OD value | 0.82? | 0.19? | 0.79? |
By the result as can be known; under the UV radiation; the cellular control unit quantity and the activity of not adding any material all have bigger decline; interpolation L-carnosine group; infringement has alleviation slightly, and has added embodiment 1 compositions of the present invention, can well the shielding angle cell plastid avoids the radiation injury of UV; basically keep cell quantity and cell viability, have and be far superior to organize 1 and the effect of group 3.
Embodiment 8
The skin protection test:
With the surfactant of embodiment 4 as test group, the common surfactant of embodiment 5 is organized in contrast, adopt Callegari Soft5.5, test 120 30-35 year women triers, experimenter's keratodermatitis moisture and skin elasticity value before record uses earlier, begin afterwards to be coated with continuously and use experimental solutions at specific part, be coated with the position is the skin of the inboard 3.0*3.0cm area of upper arm, respectively choose skin everywhere, fixedly smear respectively embodiment 4 surfactant (test group invention surfactant) and, the common surfactant of embodiment 5 (matched group 1 common surfactant), the L-carnosine moisture retention water of embodiment 6 (matched group 2L-carnosine surfactant), any skin care item (blank group) are not smeared at another place, and every day, each once was coated with continuously with after 16 weeks sooner or later, test is coated with keratodermatitis moisture and skin elasticity value in the area respectively, contrasted with trying previous crops, estimate the effective percentage that 120 tester's skin elasticitys are improved, the result is shown in table 3 and table 2.
Table 2. is coated with the effective percentage with the back experimenter's skin elasticity improvement of 16 weeks continuously
| Group | Effective percentage (%) |
| Test group | 98.3％? |
| Matched group 1 | 19.2％? |
| Matched group 2 | 20.0％? |
| Blank group | -1.7％? |
By the result of table 3 and table 4 as can be known, compare with common surfactant, the surfactant of embodiment 4 improves the elastic effectiveness of skin apparently higher than common surfactant and L-carnosine surfactant, and effective percentage exceeds 3 times than matched group.
Claims (8)
1.Quna class fibroin skin care item is characterized in that containing following component: the mixed extract of L-carnosine, lycopene, betel leaf and red algae.
2. skin care item as claimed in claim 1 is characterized in that described betel leaf extract is with after betel leaf and the red algae pulverizing, add ethanol water and extract, and extracting solution concentrates and obtains.
3. skin care item as claimed in claim 2 is characterized in that alcoholic acid mass fraction is 80-90% in the described ethanol water; The red algae of betel leaf 1-2 part weight of per 2 parts of weight mixes, and the ethanol water that adds 3-6 part weight extracts.
4. skin care item as claimed in claim 2 is characterized in that described extraction is to adopt microwave extraction 4-8 minute.
5. as the described skin care item of the arbitrary claim of claim 1～4, it is characterized in that described composition weight proportioning constitutes: L-carnosine 0.05-0.5 part, lycopene 0.05-0.5 part, the mixed extract of betel leaf and red algae is counted 12-16 part with the gross weight of betel leaf and red algae.
6. skin care item as claimed in claim 5 is characterized in that also containing vitamin B6.
7. skin care item as claimed in claim 6 is characterized in that the content of described vitamin B6 is counted 0.5-1 part with parts by weight.
8. skin care item as claimed in claim 1 is characterized in that described skin care item are protective skin cream, facial cleaning cream, cream for skin care or surfactant.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105126510A CN102018654A (en) | 2010-10-19 | 2010-10-19 | Analogous fibroin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105126510A CN102018654A (en) | 2010-10-19 | 2010-10-19 | Analogous fibroin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102018654A true CN102018654A (en) | 2011-04-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010105126510A Pending CN102018654A (en) | 2010-10-19 | 2010-10-19 | Analogous fibroin |
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| Country | Link |
|---|---|
| CN (1) | CN102018654A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105748311A (en) * | 2016-03-29 | 2016-07-13 | 苏州蔻美新材料有限公司 | Cosmetic additive and preparation method thereof |
| CN115746166A (en) * | 2022-12-01 | 2023-03-07 | 海南大学 | Piper betel leaf pectin and preparation method and application thereof |
-
2010
- 2010-10-19 CN CN2010105126510A patent/CN102018654A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105748311A (en) * | 2016-03-29 | 2016-07-13 | 苏州蔻美新材料有限公司 | Cosmetic additive and preparation method thereof |
| CN115746166A (en) * | 2022-12-01 | 2023-03-07 | 海南大学 | Piper betel leaf pectin and preparation method and application thereof |
| CN115746166B (en) * | 2022-12-01 | 2024-03-22 | 海南大学 | Fructus trichosanthis She Guojiao and preparation method and application thereof |
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Application publication date: 20110420 |