CN102016571A - 血清素转运体基因与酗酒的治疗 - Google Patents
血清素转运体基因与酗酒的治疗 Download PDFInfo
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- CN102016571A CN102016571A CN2009801152206A CN200980115220A CN102016571A CN 102016571 A CN102016571 A CN 102016571A CN 2009801152206 A CN2009801152206 A CN 2009801152206A CN 200980115220 A CN200980115220 A CN 200980115220A CN 102016571 A CN102016571 A CN 102016571A
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9406—Neurotransmitters
- G01N33/942—Serotonin, i.e. 5-hydroxy-tryptamine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/30—Psychoses; Psychiatry
- G01N2800/307—Drug dependency, e.g. alcoholism
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- General Chemical & Material Sciences (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3226308P | 2008-02-28 | 2008-02-28 | |
| US61/032,263 | 2008-02-28 | ||
| US5930108P | 2008-06-06 | 2008-06-06 | |
| US61/059,301 | 2008-06-06 | ||
| US14644009P | 2009-01-22 | 2009-01-22 | |
| US61/146,440 | 2009-01-22 | ||
| PCT/US2009/035420 WO2009108837A2 (en) | 2008-02-28 | 2009-02-27 | Serotonin transporter gene and treatment of alcoholism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102016571A true CN102016571A (zh) | 2011-04-13 |
Family
ID=41016720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009801152206A Pending CN102016571A (zh) | 2008-02-28 | 2009-02-27 | 血清素转运体基因与酗酒的治疗 |
Country Status (18)
| Country | Link |
|---|---|
| US (11) | US8697361B2 (https=) |
| EP (1) | EP2255184B1 (https=) |
| JP (1) | JP2011515076A (https=) |
| KR (1) | KR20100127799A (https=) |
| CN (1) | CN102016571A (https=) |
| AU (1) | AU2009219174B2 (https=) |
| BR (1) | BRPI0908425B8 (https=) |
| CA (1) | CA2716498C (https=) |
| DK (1) | DK2255184T3 (https=) |
| EA (1) | EA019200B1 (https=) |
| ES (1) | ES2430940T3 (https=) |
| HR (1) | HRP20130621T1 (https=) |
| IL (1) | IL207822A (https=) |
| MX (1) | MX2010009509A (https=) |
| NZ (1) | NZ588037A (https=) |
| PL (1) | PL2255184T3 (https=) |
| WO (1) | WO2009108837A2 (https=) |
| ZA (1) | ZA201006485B (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104615913A (zh) * | 2014-12-31 | 2015-05-13 | 深圳先进技术研究院 | 一种标志物相关性检测方法以及装置 |
| CN112002375A (zh) * | 2020-07-30 | 2020-11-27 | 苏州因顿医学检验实验室有限公司 | 一种酒量预测模型的构建方法 |
| CN119563945A (zh) * | 2024-11-29 | 2025-03-07 | 重庆大学 | 一种智能戒烟管理系统 |
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| US8631151B2 (en) | 2006-05-18 | 2014-01-14 | Intel Corporation | Techniques for guaranteeing bandwidth with aggregate traffic |
| JP2010513569A (ja) * | 2006-12-19 | 2010-04-30 | ユニバーシティ オブ バージニア パテント ファウンデーション | アルコール摂取に対するトピラメートおよびオンダンセトロンの併用効果 |
| CA2677205A1 (en) * | 2007-01-31 | 2008-08-07 | University Of Virginia Patent Foundation | Topiramate plus naltrexone for the treatment of addictive disorders |
| WO2009029308A1 (en) * | 2007-08-27 | 2009-03-05 | University Of Virginia Patent Foundation | Medication combinations for the treatment of alcoholism and drug addiction |
| MX2010009509A (es) | 2008-02-28 | 2010-11-30 | Univ Virginia | Gen transportador de serotonina y tratamiento de alcoholismo. |
| EP2425013A1 (en) * | 2009-05-01 | 2012-03-07 | University Of Virginia Patent Foundation | Serotonin transporter gene and treatment of alcoholism |
| US8355927B2 (en) | 2010-11-05 | 2013-01-15 | Genomind, Llc | Neuropsychiatric test reports |
| EA024450B1 (ru) | 2010-07-02 | 2016-09-30 | Юниверсити Оф Вирджиния Пэтент Фаундейшн | Молекулярно-генетический подход к лечению и диагностике алкогольной и наркотической зависимости |
| JP5899527B2 (ja) * | 2011-03-14 | 2016-04-06 | 国立研究開発法人理化学研究所 | 第6染色体短腕21.33領域の一塩基多型に基づく抗てんかん薬による薬疹リスクの検査方法 |
| US9965584B2 (en) | 2011-05-17 | 2018-05-08 | National Ict Australia Limited | Identifying interacting DNA loci using a contingency table, classification rules and statistical significance |
| EP2751137A4 (en) * | 2011-09-09 | 2015-06-03 | Univ Virginia Patent Found | MOLECULAR GENETIC APPROACH FOR THE TREATMENT AND DIAGNOSIS OF ALCOHOL AND DRUG INDEPENDENCE |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
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| JP2015165780A (ja) * | 2014-03-04 | 2015-09-24 | 大学共同利用機関法人情報・システム研究機構 | 視床−皮質軸索でegfpを発現するマウス |
| ES2546896B1 (es) * | 2014-03-26 | 2016-07-07 | Universitat De Les Illes Balears | Método para la predicción y/o la prevención de sobrepeso, obesidad y/o sus complicaciones mediante análisis de expresión génica |
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| RU2695659C1 (ru) * | 2018-09-28 | 2019-07-25 | Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия непрерывного профессионального образования" Министерства здравоохранения Российской Федерации (ФГБОУ ДПО РМАНПО Минздрава России) | Способ прогнозирования оценки эффективности терапии промазином для лечения расстройств, сопровождающихся развитием психотической симптоматики |
| KR101950372B1 (ko) * | 2018-10-30 | 2019-02-20 | 한국화학연구원 | 스테로이드 대사 변화 분석 방법, 이에 따른 인터넷 또는 스마트폰 중독 예측방법 및 이를 실현하기 위한 프로그램이 저장된 컴퓨터 판독 가능한 기록 매체 |
| RU2700565C1 (ru) * | 2019-06-06 | 2019-09-19 | Федеральное бюджетное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН "ФНЦ медико-профилактических технологий управления рисками здоровью | Способ определения предрасположенности к развитию ожирения у детей в условиях избыточной контаминации алюминием |
| US12475984B2 (en) * | 2019-08-05 | 2025-11-18 | Rxassurance Corporation | Techniques for providing interactive clinical decision support for drug dosage reduction |
| KR102203807B1 (ko) * | 2019-08-05 | 2021-01-15 | 한국과학기술연구원 | 중독의 진단용 조성물, 키트 및 이를 이용한 중독의 진단을 위한 세로토닌의 검출 방법 |
| RU2722834C1 (ru) * | 2019-12-19 | 2020-06-04 | Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия непрерывного профессионального образования" Министерства здравоохранения Российской Федерации (ФГБОУ ДПО РМАНПО Минздрава России) | Способ прогнозирования оценки эффективности терапии флувоксамином для лечения расстройств, сопровождающихся развитием депрессивной симптоматики |
| WO2021127391A1 (en) * | 2019-12-20 | 2021-06-24 | The Jackson Laboratory | Molecular targets for addiction |
| US20220117916A1 (en) * | 2020-10-19 | 2022-04-21 | SafeRx Pharmaceuticals, LLC | Combination Products to Mitigate the Risk of Non-Benzodiazepine Benzodiazepine Agonist Adverse Reaction and Overdose |
| RU2753899C1 (ru) * | 2020-11-23 | 2021-08-24 | Александр Борисович Мулик | Способ прогнозирования риска развития алкоголизации населения локальных территорий |
| WO2022117573A1 (en) * | 2020-12-01 | 2022-06-09 | Fundació Institut De Recerca De L'hospital De La Santa Creu I Sant Pau | Predicting behavioural addictions |
| RU2767699C1 (ru) * | 2021-09-02 | 2022-03-18 | Федеральное государственное бюджетное научное учреждение «Томский национальный исследовательский медицинский центр Российской академии наук» (Томский НИМЦ) | Способ прогнозирования коморбидного течения аффективных расстройств и алкоголизма на основе определения белков сыворотки крови |
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| CN112002375B (zh) * | 2020-07-30 | 2022-10-14 | 苏州因顿医学检验实验室有限公司 | 一种酒量预测模型的构建方法 |
| CN119563945A (zh) * | 2024-11-29 | 2025-03-07 | 重庆大学 | 一种智能戒烟管理系统 |
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