CN102008426A - Cosmetic composition with function of eliminating free radical - Google Patents

Cosmetic composition with function of eliminating free radical Download PDF

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Publication number
CN102008426A
CN102008426A CN2009101953579A CN200910195357A CN102008426A CN 102008426 A CN102008426 A CN 102008426A CN 2009101953579 A CN2009101953579 A CN 2009101953579A CN 200910195357 A CN200910195357 A CN 200910195357A CN 102008426 A CN102008426 A CN 102008426A
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extract
cosmetic composition
free radical
effect
percentage
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CN2009101953579A
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金素心
朱卫
吴小惠
李新华
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SHANGHAI LEASUN BIOCHEMICAL CO Ltd
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SHANGHAI LEASUN BIOCHEMICAL CO Ltd
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Abstract

The invention relates to a cosmetic composition with the function of eliminating free radical. The cosmetic composition comprises a flavonoids extract containing flavonoids compounds, a yeast extract containing reduced glutathione, a natural fruit acid extract containing alpha hydroxy acid and the balance of carriers acceptable for cosmetology. The flavonoids extract is extracted from pomace, the content range of the flavonoids extract is 0.05% to 0.4% by weight percent, the content range of the yeast extract is 0.1% to 20% by weight percent, and the content range of the natural fruit acid extract is 0.1% to 10% by weight percent. The cosmetic composition provided by the invention can effectively eliminate the free radical so as to make skin maintain flexibility and softness and improve skin wrinkles and light damage, has cosmetic results of oxidation resistance and aging resistance, and can be widely applied to various types of cosmetics and skin care products.

Description

A kind of cosmetic composition with the effect of removing free radical
Technical field
The present invention relates to a kind of cosmetic composition, specifically, the present invention relates to a kind of cosmetic composition of removing the free radical effect that has.
Background technology
People's skin aging comprises inherent aging and photo-aging.Inherent aging, except intrinsic inherited genetic factors, mainly be because the variation of skin supporting tissue-skin corium that the attack of free radical causes, cause skin forfeiture water holding capacity, the variation that puts in order of elastic fibers and collagen, the mechanical force and the flexibility decrease that cause skin to have, the crack of skin tendency increases, and drying, coarse, wrinkle, phenomenon such as lax will appear in skin.Photo-aging is by the skin aging that causes sunshine, and it is to cause Keratoderma disease, black speck, wrinkle and elastotic reason.The dyskeratosis of skin can show as that epidermis thickens and densification, and it can cause xerosis cutis and cause many as dermatosiss such as eczema, tinea, acne.So the aging of skin and the formation of wrinkle are the results of a composite factor influence.
Aging is the natural phenomena in the biological life process, and is irresistible, but can delay; Aging rate is subjected to the control of itself Gene Handling and external factor such as surrounding.Therefore, the cosmetics of anti aging effect extensively are subjected to women's favor.But merely anti-aging product is out-of-date, more people begin to pursue have the skin that compacts, desalination wrinkle and senile plaque and resist the cosmetics of the comprehensive beauty effect of ultraviolet injury.Because, extract and isolated the very additive of high bioactivity arranged from various natural materials, human body is endangered little, cosmetic result is remarkable, so composite cosmetic composition with comprehensive antiageing effect has vast market prospect from natural extract.
Summary of the invention
The invention provides a kind of by the composite cosmetic composition of natural extract, said composition can make skin become soft, smooth, can regulate the water balance of skin surface automatically, play the effect of preserving moisture, lubricating, can also reduce the invasion and attack of external factor to skin, smooth away wrinkles thereby reach, keep the purpose of competent moisture of skin and delay skin aging.
In order to achieve the above object, the invention provides a kind of cosmetic composition of removing the free radical effect that has, said composition comprises:
By the flavone extract that contains flavone compound of pomace extraction gained, the content range of this flavone extract is percentage by weight 0.05%-0.4%;
The yeast extract that contains reduced glutathion, the content range of this yeast extract are percentage by weight 0.1%-20%;
The natural tartaric acid extract that contains 'alpha '-hydroxy acids, the content range of this fruit acid extract are percentage by weight 0.1-10%;
Surplus is the beauty treatment acceptable carrier.
Described beauty treatment acceptable carrier, refer on the Dermatology/cosmetics on acceptable carrier, be suitable for contacting, not undesirable properties such as toxicity, incompatibility, unstability, anaphylaxis improperly with human keratinous tissue; The raw material etc. that it comprises cosmetic additive, beneficial skin material and is usually used in skin care item, for example adjuvant commonly used in the cosmetics such as water, antiseptic, silicone oil, alcohol ester, vitamin, coloring agent, cleaning agent, thickening agent, opacifier, diluent, dispersant, emulsifying agent.
More preferably, the content range of described yeast extract is percentage by weight 1%-10%.
More preferably, the content range of described fruit acid extract is percentage by weight 0.5-6%.
Particularly, the percentage by weight of described flavone compound content in flavone extract is 85%-99%, is preferably 85%-90%.
According to the free-radical theory of aging, reactive oxygen free radical and unsaturated fatty acid effect excessive in the body generate materials such as malonaldehyde, and effect such as the protein on malonaldehyde and the cell membrane generates brown pigment, and being deposited in skin just becomes various mottles.Free radical also can make the crosslinked and degeneration of collagen fiber, the elastic fiber in the skin, become fragile, follows the string, and when the water deficient in the skin, makes the elastic fiber fracture easily and forms wrinkle.
By the structure of flavone compound as can be known, the delocalization of the electronics on the phenyl ring makes the easy ionizing of phenolic hydroxyl group, be strong hydrogen donor, can make radical reduction, thereby end radical chain reaction with high oxidation, stop new free-radical generating, avoid the effect of radical pair cells injury.Thus, the flavone extract that contains flavone compound that extract to obtain by pomace, because of containing a large amount of hydrogen donors, free radical that can elimination activity has stronger antioxidant activity and radical scavenging activity.
Experiment showed, by pomace and extract the flavone extract that contains flavone compound that obtains that can improve skin elasticity by removing the generation of free radical delaying skin wrinkle, DNA avoids the ultraviolet radiation damage in the protective, reduces pigmentation.
The percentage by weight of described reduced glutathion content in yeast extract is 5%-15%, is preferably 5%-10%; Described yeast extract extracts from mycocandida Candida or Saccharomyces Saccharomyces yeast.
Contain active sulfydryl one SH in the structure of reduced glutathion (GSH), easy oxidized deoxidation, this specific structure makes it become main free radical scavenger in the body.Many free radicals meeting damaging cells films that the body intracellular metabolic produces, the invasion and attack life macromolecule impel body aging, and GSH can be removed free radical, plays strong protective effect.For example in cell, generate small amount of H 2O 2The time, GSH is under the effect of glutathion peroxidase, H 2O 2Be reduced into H 2O, himself is oxidized to GSSG, under the glutathion reductase catalytic action of GSSG in being present in liver and erythrocyte, accepts H and is reduced into GSH, makes the cleaning reaction of interior free yl can continue to carry out.
Thus, the yeast extract that contains reduced glutathion has the elimination free radical, and function in delaying senility can prevent skin aging and pigmentation, reduces melanic formation, improves the skin oxidation resistance and makes skin produce gloss.
The percentage by weight of described 'alpha '-hydroxy acids content in the fruit acid extract is 5-30%; Described 'alpha '-hydroxy acids refers to one or more the mixture in hydroxyacetic acid, L-lactic acid, citric acid, malic acid, tartaric acid, glucuronic acid, galacturonic acid, mandelic acid and their salt derivative.
The described fruit acid extract that contains 'alpha '-hydroxy acids is to extract from one or more plants of Fructus Citri Limoniae (Citrus Limonium), Caulis Sacchari sinensis (Saccharum Officinalis), Pericarpium Citri tangerinae (Vaccinium Myrtillus), Fructus Citri sinensis (Citrus Sinesis), Fructus Mali pumilae (Pyrus Malus), Acer saccharum Marsh. (Acer Saccharum), and 'alpha '-hydroxy acids claims fruit acid again.Wherein, 'alpha '-hydroxy acids can reduce the thickness of dyskeratosis epidermis, when newborn horny layer forms, can reduce the adhesion of epidermis cell, makes the aged dead cell of epidermis be easier to fall in flakes; And change the epidermis outward appearance, strengthen cuticular pliability.It can promote epidermal growth again simultaneously, accelerates the renewal of epidermis cell.
The cosmetics that contain 'alpha '-hydroxy acids can increase the water holding capacity of skin, remove tiny wrinkle rapidly, help to eliminate photoaging (photic damage), epidermis is thickened, the attenuation of corium sheath, hypopigmentation, skin moisturizing makes skin seem more plentiful, softness and high resilience.
The above-mentioned flavonoids from apple extract that contains flavone compound, the natural tartaric acid extract that contains the yeast extract of reduced glutathion and contain 'alpha '-hydroxy acids are made up by a certain percentage, can play antioxidation, aging-resistant comprehensive beauty effect, make skin keep elasticity and flexibility, improve skin fine wrinkle and photic damage.Cosmetic composition provided by the invention can be widely used in various forms of cosmetics such as facial film, gel, emulsion, cream frost, water preparation.
The specific embodiment
Described flavone extract is to adopt pomace, extracts through the ethanol heated and stirred, filters, concentrating under reduced pressure, the centrifugal lower sediment of removing, with the concentrated solution on upper strata by the sephadex lh-20 resin column, adopt ethanol elution, eluent concentrates the back spray drying, makes flavonoids from apple powder agent.
Described yeast extract is that yeast is carried out seed culture earlier, is fermentation culture then, adopt high speed centrifugation to carry out cell separation again, after the hot-water extraction, separate again, acquisition contains the extract of glutathion, adopts ion-exchange resin purification again, and last concentrate drying obtains.
Described natural tartaric acid extract is the fruit juice of the Fructus Citri Limoniae of will squeeze, Caulis Sacchari sinensis, Pericarpium Citri tangerinae, Fructus Citri sinensis, Fructus Mali pumilae, Acer saccharum Marsh., by repeatedly centrifugal filtration, remove impurity, acquisition contains the supernatant liquid of 'alpha '-hydroxy acids, concentrates the back and adopts ion-exchange resin purification, and last concentrate drying obtains.
To relevant details of the present invention be further described by embodiment below.
Embodiment 1: beauty mask:
Figure B2009101953579D0000041
Figure B2009101953579D0000051
Preparation method: the biphase raw material of A, B is heated to 85 degree respectively, B is slowly added the A phase mutually, 3000 rev/mins of homogenizing keep stopping homogenizing after 5 minutes, continue to stir, and add C and neutralize mutually, are cooled to 45 degree, add D and stir mutually, can obtain beauty mask.
Above-mentioned beauty mask can use every day, evenly is applied in face during use, stops flush away after 10 minutes.This beauty mask has the effect that promotes skin cell proliferation, delaying decrepitude of skin, improves skin fine wrinkle and photic damage, raising skin elasticity and flexibility.
Embodiment 2: beauty cosmetic water
Figure B2009101953579D0000052
Preparation method: A phase raw material is heated to 85 degree, and the back that stirs kept 5 minutes, was cooled to 45 degree and added the B phase, added the C phase at last, and stirring to obtain beauty cosmetic water.
Above-mentioned beauty cosmetic water can use every day, evenly is applied in face during use, and skin is fully absorbed.This beauty cosmetic water has the effect that promotes skin cell proliferation, delaying decrepitude of skin, improves skin fine wrinkle and photic damage, raising skin elasticity and flexibility.
Embodiment 3: the beauty treatment emulsion
Figure B2009101953579D0000061
Preparation method: the biphase raw material of A, B is heated to 85 degree respectively, A is slowly added B phase, 3000 rev/mins of homogenizing mutually, keep stopping homogenizing after 5 minutes, continue to stir, add C and neutralize mutually, be cooled to 45 degree, add D and stir mutually with E mutually, can obtain the emulsion of improving looks.
Above-mentioned beauty treatment emulsion can be used every day, evenly is applied in face during use.This beauty treatment emulsion has the effect that promotes skin cell proliferation, delaying decrepitude of skin, improves skin fine wrinkle and photic damage, raising skin elasticity and flexibility.
Embodiment 4: cosmetic cream
Figure B2009101953579D0000071
Preparation method: the biphase raw material of A, B is heated to 85 degree respectively, A is slowly added the B phase mutually, 3000 rev/mins of homogenizing keep stopping homogenizing after 5 minutes, continue to stir, and add C and neutralize mutually, are cooled to 50 degree, add D and stir mutually with E mutually, can obtain cosmetic cream.
Above-mentioned cosmetic cream can use every day, evenly is applied in face during use.This beauty treatment emulsion has the effect that promotes skin cell proliferation, delaying decrepitude of skin, improves skin fine wrinkle and photic damage, raising skin elasticity and flexibility.
Embodiment 5: the beauty treatment essence
Figure B2009101953579D0000081
Preparation method: A phase raw material is heated to 85 degree, and the back that stirs kept 5 minutes, was cooled to 50 degree and added the B phase, added the C phase at last, and stirring to obtain the essence of improving looks.
Above-mentioned beauty treatment essence can use every day, evenly is applied in face during use, and skin is fully absorbed.This beauty treatment essence has the effect that promotes skin cell proliferation, delaying decrepitude of skin, improves skin fine wrinkle and photic damage, raising skin elasticity and flexibility.
Although content of the present invention has been done detailed introduction by above preferred embodiment, will be appreciated that above-mentioned description should not be considered to limitation of the present invention.After those skilled in the art have read foregoing, for multiple modification of the present invention with to substitute all will be conspicuous.Therefore, protection scope of the present invention should be limited to the appended claims.

Claims (10)

1. one kind has the cosmetic composition of removing the free radical effect, it is characterized in that described compositions comprises:
By the flavone extract that contains flavone compound of pomace extraction gained, the content range of this flavone extract is percentage by weight 0.05%-0.4%;
The yeast extract that contains reduced glutathion, the content range of this yeast extract are percentage by weight 0.1%-20%;
The natural tartaric acid extract that contains 'alpha '-hydroxy acids, the content range of this fruit acid extract are percentage by weight 0.1-10%;
Surplus is the beauty treatment acceptable carrier.
2. the cosmetic composition with the effect of removing free radical as claimed in claim 1 is characterized in that the content range of described yeast extract is percentage by weight 1%-10%.
3. the cosmetic composition with the effect of removing free radical as claimed in claim 1 is characterized in that the content range of described fruit acid extract is percentage by weight 0.5-6%.
4. the cosmetic composition with the effect of removing free radical as claimed in claim 1 is characterized in that the percentage by weight of described flavone compound content in flavone extract is 85%-99%.
5. the cosmetic composition with the effect of removing free radical as claimed in claim 1 is characterized in that the percentage by weight of described flavone compound content in flavone extract is 85%-90%.
6. the cosmetic composition with the effect of removing free radical as claimed in claim 1 is characterized in that the percentage by weight of described reduced glutathion content in yeast extract is 5%-15%.
7. the cosmetic composition with the effect of removing free radical as claimed in claim 1 is characterized in that the percentage by weight of described reduced glutathion content in yeast extract is 5%-10%.
8. the cosmetic composition with the effect of removing free radical as claimed in claim 1 is characterized in that the percentage by weight of described 'alpha '-hydroxy acids content in the fruit acid extract is 5-30%.
9. the cosmetic composition with the effect of removing free radical as claimed in claim 1, it is characterized in that described 'alpha '-hydroxy acids refers to one or more the mixture in hydroxyacetic acid, L-lactic acid, citric acid, malic acid, tartaric acid, glucuronic acid, galacturonic acid, mandelic acid and their salt derivative.
10. the cosmetic composition with the effect of removing free radical as claimed in claim 1 is characterized in that described fruit acid extract is to extract from one or more plants of Fructus Citri Limoniae, Caulis Sacchari sinensis, Pericarpium Citri tangerinae, Fructus Citri sinensis, Fructus Mali pumilae, Acer saccharum Marsh..
CN2009101953579A 2009-09-08 2009-09-08 Cosmetic composition with function of eliminating free radical Pending CN102008426A (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103857382A (en) * 2011-09-30 2014-06-11 Elc管理公司 Regimen for reducing the appearance of thinning hair
US9155768B2 (en) 2011-09-30 2015-10-13 Elc Management Llc Regimen for reducing the appearance of thinning hair
CN105078814A (en) * 2014-12-19 2015-11-25 赵雅珺 Face cleanser
CN105434321A (en) * 2015-12-22 2016-03-30 温州任和教育科技有限责任公司 Whitening freckle-removing mask and preparation method thereof
CN105662940A (en) * 2016-01-05 2016-06-15 深圳典立生物科技有限公司 Active composition, and preparation method and application thereof in cosmetics or skin care products
JPWO2015151867A1 (en) * 2014-03-31 2017-04-13 興人ライフサイエンス株式会社 Utilization of yeast extract containing glutathione as a melanin production inhibitor
CN107951809A (en) * 2018-01-10 2018-04-24 福建师范大学 A kind of whitening maintenance Essence containing Caulis Sacchari sinensis extract and preparation method thereof
CN110075366A (en) * 2019-04-01 2019-08-02 杨青青 A kind of anti-oxidant lifting esthetic line of biological absorbable and its preparation method and application
CN113226273A (en) * 2018-10-30 2021-08-06 莱雅公司 Cosmetic composition for skin care

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103857382A (en) * 2011-09-30 2014-06-11 Elc管理公司 Regimen for reducing the appearance of thinning hair
US9155768B2 (en) 2011-09-30 2015-10-13 Elc Management Llc Regimen for reducing the appearance of thinning hair
CN103857382B (en) * 2011-09-30 2016-09-28 Elc管理公司 For alleviating the scheme of the outward appearance of sparse hair
JPWO2015151867A1 (en) * 2014-03-31 2017-04-13 興人ライフサイエンス株式会社 Utilization of yeast extract containing glutathione as a melanin production inhibitor
CN105078814A (en) * 2014-12-19 2015-11-25 赵雅珺 Face cleanser
CN105434321A (en) * 2015-12-22 2016-03-30 温州任和教育科技有限责任公司 Whitening freckle-removing mask and preparation method thereof
CN105662940A (en) * 2016-01-05 2016-06-15 深圳典立生物科技有限公司 Active composition, and preparation method and application thereof in cosmetics or skin care products
CN105662940B (en) * 2016-01-05 2018-05-18 深圳典立生物科技有限公司 Active compound and preparation method thereof and its application in cosmetics or skin care item
CN107951809A (en) * 2018-01-10 2018-04-24 福建师范大学 A kind of whitening maintenance Essence containing Caulis Sacchari sinensis extract and preparation method thereof
CN113226273A (en) * 2018-10-30 2021-08-06 莱雅公司 Cosmetic composition for skin care
CN110075366A (en) * 2019-04-01 2019-08-02 杨青青 A kind of anti-oxidant lifting esthetic line of biological absorbable and its preparation method and application

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Application publication date: 20110413