CN103565729B - Condensation and preparation method thereof is repaired in a kind of black Fructus Lycii moisturizing - Google Patents
Condensation and preparation method thereof is repaired in a kind of black Fructus Lycii moisturizing Download PDFInfo
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- CN103565729B CN103565729B CN201310560191.2A CN201310560191A CN103565729B CN 103565729 B CN103565729 B CN 103565729B CN 201310560191 A CN201310560191 A CN 201310560191A CN 103565729 B CN103565729 B CN 103565729B
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- fructus lycii
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Abstract
The invention provides a kind of black Fructus Lycii moisturizing and repair condensation.Present invention also offers moisturizing and repair the preparation method of condensation.Condensation is repaired in moisturizing of the present invention, uses more convenient, just can reach moisturizing from inside to outside and repair the purpose of skin during sleeping.The black Fructus Lycii of interpolation, yeast, Sargassum, propolis extract, skin is made to carry out long-acting moisturizing at night, supplement aminoacid, abundant maintenance and be dried low and deep sub-health state, excite skin water vigor, infiltration lane is opened for skin, osmotrophy material, accelerates the self-regeneration of skin, strengthens skin updating ability, water is tender, compact, ruddy glossy, high resilience to make skin recover, and also has freckle removing and whitening, antioxidation, anti-aging effect.The present invention is without artificial color, using natural biological extract as active substance, plays its given efficacy, and permanence operation is obvious, and processing technology is simple, best in quality, and safety has no side effect.
Description
Technical field
The present invention relates to a kind of black Fructus Lycii moisturizing and repair condensation and preparation method thereof.
Background technology
Skin, through the metabolism of a day, is done reparation maintenance process to night and can promote skin by skin
Matter, particularly before sleeping or take a shower after, body and mind is joyful, look quiet, is skin absorption nutrient, enters
The inning that row moisturizing is repaired.
Traditional stripping facial film, powder face pack etc. are all typically necessary coating about 30 minutes, finally must
Use clean water skin, and facial film can be done on limit after applying ointment or plaster for a long time, can absorb the water in skin on the contrary
Point, skin is caused damage.For busy crowd, the facial film of the above-mentioned type exists many
Inconvenience.Disposable sleep mask becomes more and more popular, because not only having effect of common facial film, and uses
Convenient, utilize a thick layer of elite to apply face, intercepted contacting of skin and air, decreased moisture
Evaporation, increases cuticular humidity, horny layer softening layer, beneficially skin absorption nutritional labeling, repairs flesh
Skin.Skin moisture is full, will smooth delicacy, microgroove also can shoal disappearance, and skin quality is improved.
Summary of the invention
It is an object of the invention to provide a kind of moisturizing reparation with natural biological extract as active component to coagulate
Dew and preparation method thereof.
The invention provides a kind of black Fructus Lycii moisturizing and repair condensation, it is by following weight percentage
Supplementary material is prepared from:
Further, it is to be prepared from by the supplementary material of following weight percentage:
In the present invention, multiple natural extract is applied in combination, has played the best skin care activity,
The skin care item that a kind of skin effect is more preferable, safety is high are provided for market.
Wherein, described black Fructus Lycii extracting solution is the water extract of black Fructus Lycii fruit powder；Preferably, Radix osteomelis schwerinais Chinese holly
The preparation method of Qi extracting solution is as follows: precision weighs the dried powder of 5g black Fructus Lycii, adds 50mL and goes
Ion distilled water, extracts 2 times in 50 DEG C of water-baths, and each 15 minutes, added water after filtration 100mL by residue
Extract 2 times at 75 DEG C, each 15 minutes, merge twice extracting solution, filter, be evaporated to 10g/mL,
Obtain black Fructus Lycii extracting solution.
Wherein, the preparation method of yeast extract is as follows: by beer yeast washing impurity-removing in 0-4 DEG C of water
Matter, de-hardship, then carry out coarse filtration, obtain the yeast slurry containing solid content, be subsequently adding accelerator, matter
Wall separating medium and NaOH, regulate pH to 6.0～7.0, and at a temperature of 52 DEG C ± 2 DEG C, 2-2.5 is extracted in self-dissolving
Hour, then boil, enzyme denaturing, cooling standing, centrifugation, removing cell wall fragments, vacuum decompression is dense
Being reduced to concentration is 10g/mL, obtains yeast extract.
Wherein, the preparation method of seaweed extracted liquor is as follows: be 2～4 by the Sargassum pH after the removal of impurity
Dilute acid soln is carried out, rubs, and grinds homogenate in the dilute acid soln that pH is 2～4, then will
Sargassum after homogenate temperature 121～135 DEG C, ripening sterilizing 0.5～2 hours under pressure 1～5MPa, fall
Sargassum slurry after solution adds alkali and adjusts pH to 5.0-7.0, inoculates and cultivate in advance in the Sargassum serosity after adjusting
Good probiotic bacteria strain normal fermentation, then the serosity after fermentation add algin oligosaccharide allocate,
Probiotic bacteria is protected, breeds, be deployed into the serosity that concentration is 20g/mL, be seaweed extracted liquor.
Wherein, the preparation method of propolis extract is as follows: propolis goes the temperature below-5 DEG C after the removal of impurity
Lower freezing 45h～52h of degree, then by the propolis quick crashing after freezing, screening, by the propolis after screening
Add ethanol solution at a temperature of 22 DEG C～26 DEG C, impregnate 5h～7h, take out after then standing 1.5h～2.5h
The supernatant, remaining material adds ethanol solution again and continues dipping, stands, so repeats at least three times, and
The supernatant that rear merging obtains for each time cools to less than 5 DEG C, filters, by filtrate below 50 DEG C
Carrying out heating evaporation, being concentrated into concentration is 10g/mL, obtains propolis extract.
Wherein, described wetting agent selected from hyaluronic acid, allantoin, collagen protein, silk peptide, glycerol, 1,3-
One or more in butanediol, Lubrajel CG.
Wherein, described solubilizing agent is selected from HPS, Cremophor RH40, the PPG-1-PEG-9 month
One in osmanthus glycol ethers, PEG-400 Polyethylene Glycol, polyoxyethylated coconut oil alcohol-7 (AEO-7) or
Several.
Wherein, described antibacterial is selected from Kathon CG, Germall II, Germall Plus, Glydant
One or more in PLUS.
Present invention also offers above-mentioned black Fructus Lycii moisturizing and repair the preparation method of condensation, it includes grasping as follows
Make step:
(1) raw material is weighed by weight ratio；
(2) taking Acritamer 940 to add water 80 DEG C ± 5 DEG C stirring and dissolving, being made into concentration is 2%g/ml's
Colloid solution is standby；
(3) by wetting agent, methyl hydroxybenzoate, disodiumedetate, solubilizing agent and water 70～90
Fully dissolve at DEG C, form the solution A of transparent clarification；
(4) colloid solution, triethanolamine are joined in solution A, at 60～80 DEG C, continue stirring
It is uniformly dissolved, forms clear gum mixture；
(5) when said mixture is cooled to 40～50 DEG C, add antibacterial, black Fructus Lycii extracting solution,
Yeast extract, seaweed extracted liquor, propolis extract and essence, stir, and obtains black Fructus Lycii and protects
Wet reparation condensation.
Wherein, black Fructus Lycii extracting solution is the water extract of black Fructus Lycii fruit powder.In lycium ruthenicum fruit rich in
The compositions such as protein, aminoacid, flavone, procyanidin, fat, polysaccharide, vitamin E.Protein
It is the structural material of human body skin, gives skin with nutrition, impaired cell, tissue can be made to obtain in time
High-quality repairing, makes skin gloss high resilience, delaying senility.Containing except color in lycium ruthenicum fruit
17 kinds of aminoacid beyond propylhomoserin, aminoacid is to constitute organism protein closely bound up with vital movement
One of most basic material, it is provided that nutrition, promote growth, maintain normal metabolism.Radix osteomelis schwerinais
Wolfberry pigment is anthocyanin class and flavone compound, and its non-oxidizability is significantly stronger than ratio vitamin E, and
Visible ray and ultraviolet there is Stabilization.The non-oxidizability of flavone is mainly manifested in removing free radical and resists
The aspects such as liposome peroxidation.
Yeast extract is rich in active skull cap components such as the aminoacid of little molecule, peptide, nucleotide, vitamin
Material, wherein amino acid content more than 30%, total protein more than 50%, nucleotide more than 10%.Core
Acid and nucleotide are the central genetic materials of human body, have enhancing metabolism, improve protein synthesis speed
The effects such as degree, strengthen immune function, enhancement of SOD activity, improve skin antiradical activities, it is provided that skin
Skin nutrition, adjusts sebum secretion, promotes collagen protein synthesis, smoothes away wrinkles, isolation radiation, prevents purple
Outer line absorption.Additionally, the nutrient such as vitamin a small amount of in product and mineral can also carry for skin
For sufficient nutrition.
Seaweed extracted liquor is the marine organisms product of a kind of pure natural, include abundant algin acid, crude protein,
Multivitamin, enzyme, trace element etc., these nutrients can reduce skin surface after skin absorption
Blood fat, promote epidermis cell hemopoietic function, can to cell in vitro produce bacteriostasis, also have moisturizing,
Smooth function.It addition, a large amount of aniones contained, fibrocyte can be stimulated to generate collagen protein and elasticity
Albumen, promotes the metabolism of skin, imparts its crease-resistant, effect of defying age.
In propolis extract rich in multiple flavone compound, terpenoid, mineral, trace element,
Vitamin, organic acid, aminoacid etc..Flavonoid substances has extremely strong antioxidation, stops skin
In the generation of free radical, senile plaque, slow down aging, antiinflammatory, anti-acne can be eliminated, the most absorbable
200-450nm length ultraviolet line, effectively stops and absorbs the ultraviolet injury to human body.In propolis
Galangin, A Wei acid, caffeic acid and salicylic acid, have stronger anti-inflammation, the work of horny layer softening
With, can effectively kill and suppress the pathogenic bacterium such as corynebacterium acnes, acarid, remove the hair funnel blocked,
Facial acne is had significant therapeutic effect.
Condensation is repaired in moisturizing of the present invention, uses more convenient, just can reach and protect from inside to outside during sleeping
The purpose of wet reparation skin.The black Fructus Lycii of interpolation, yeast, Sargassum, propolis extract, make skin exist
Carry out long-acting moisturizing night, supplement aminoacid, abundant maintenance and be dried low and deep sub-health state, excite flesh
Skin water vigor, opens infiltration lane, osmotrophy material for skin, accelerates the self-regeneration of skin,
Strengthening skin updating ability, water is tender, compact, ruddy glossy, high resilience to make skin recover, and also has
There are freckle removing and whitening, antioxidation, anti-aging effect.The present invention is without artificial color, with natural biological
Extract, as active substance, plays its given efficacy, and permanence operation is obvious, and processing technology
Simply, best in quality, safety has no side effect.
Below by way of detailed description of the invention, the scope of the present invention is further elaborated and illustrates, but this
Bright protection domain is not limited thereto, and any those of ordinary skill in the art disclosed herein
In technical scope, all can should contain the protection in the present invention without the amendment of creative work or replacement
Within the scope of.
Detailed description of the invention
The preparation method of yeast extract is as follows: by beer yeast washing impurity-removing matter, de-in 0-4 DEG C of water
Hardship, then carry out coarse filtration, obtain the yeast slurry containing solid content, be subsequently adding accelerator, plasmolysis
Agent and NaOH, regulate pH to 6.0～7.0, and at a temperature of 52 DEG C ± 2 DEG C, self-dissolving is extracted 2-2.5 hour,
Boil again, enzyme denaturing, cooling standing, centrifugation, removing cell wall fragments, vacuum-concentrcted is to the denseest
Degree is 10g/mL, obtains yeast extract.
The preparation method of seaweed extracted liquor is as follows: by molten for the diluted acid that Sargassum pH is 2～4 after the removal of impurity
Liquid is carried out, rubs, and grinds homogenate in the dilute acid soln that pH is 2～4, after being then homogenized
Sargassum temperature 121～135 DEG C, ripening sterilizing 0.5～2 hours under pressure 1～5MPa, after degraded
Sargassum slurry adds alkali and adjusts pH to 5.0-7.0, inoculates the most cultured benefit in the Sargassum serosity after adjusting
Raw bacterium strain normal fermentation, then the serosity after fermentation add algin oligosaccharide allocate, to benefit
Raw bacterium carries out protecting, breeding, and is deployed into the serosity that concentration is 20g/mL, is seaweed extracted liquor.
The preparation method of propolis extract is as follows: gone by propolis after the removal of impurity at a temperature of below-5 DEG C cold
Freeze 45h～52h, then by the propolis quick crashing after freezing, screening, the propolis after screening is added second
Alcoholic solution impregnates 5h～7h at a temperature of 22 DEG C～26 DEG C, takes out upper strata clear after then standing 1.5h～2.5h
Liquid, remaining material adds ethanol solution again and continues dipping, stands, so repeats at least three times, then merge
The supernatant that each time obtains cools to less than 5 DEG C, filters, filtrate is added below 50 DEG C
Thermal evaporation, being concentrated into concentration is 10g/mL, obtains propolis extract.
The water extract that black Fructus Lycii extracting solution is black Fructus Lycii fruit powder that the present invention uses, its concrete side of preparation
Method may is that precision weighs the dried powder of 5g black Fructus Lycii, adds 50mL deionized-distilled water,
Extracting 2 times in 50 DEG C of water-baths, each 15 minutes, the 100mL that added water by residue after filtration carried at 75 DEG C
Take 2 times, each 15 minutes, merge twice extracting solution, filter, be evaporated to 10g/mL, to obtain final product
Black Fructus Lycii extracting solution.
Concentration after concentrating in the present invention is all to calculate the ratio of gained with the mass/volume of concentrated solution.
In the embodiment of the present invention, each component is shown in Table 1, and proportional quantity is with mass percent example.
Table 1
The preparation method of the various embodiments described above is all according to following steps:
(1) Acritamer 940 is added water about 80 DEG C stirring and dissolving, be made into the colloid that concentration is 2%g/ml molten
Liquid is standby；
(2) by wetting agent, methyl hydroxybenzoate, disodiumedetate, solubilizing agent and deionized water 70～90
Fully dissolve at DEG C, form the solution of transparent clarification；
(3) the Acritamer 940 solution that concentration is 2%, the triethanolamine (1) prepared joins in (2) solution,
At 60～80 DEG C, continue stirring and dissolving uniform, form clear gum mixture；
(4) when said mixture is cooled to 40～50 DEG C, antibacterial, black Fructus Lycii extracting solution, yeast are added
Extracting solution, seaweed extracted liquor, propolis extract and essence, stir, and obtains black Fructus Lycii moisturizing and repaiies
Multiple condensation.
Embodiment 9
The Detection of Stability of the embodiment of the present invention 6 product:
1, pH value is 6.8.
2, heat resistant test, puts into calorstat (40 ± 1) DEG C the sample of Packing Intact and keeps 24h, extensive
Answer to room temperature without oil-water separation phenomenon.
3, low temperature resistant test, the sample of Packing Intact put in refrigerator-5～-10 DEG C place 24h, extensive
Answer to room temperature without layering, coarse, metachromatism.
4, centrifugal test, places the sample of Packing Intact in centrifuge with 2000 revs/min, centrifugal
30 minutes, without oil-water separation phenomenon.
As can be seen here, the facial cream of the embodiment of the present invention 6 preparation has good stability.
Embodiment 10 clinical experiment of the present invention and result
In order to test the moisturizing repairing effect of the present invention, carry out investigation on probation and tested:
1, respondent: choose the dry skin of areal, neutral skin, oily skin aspiration on probation
Each 10 people of person；
2, control time: on June 10 ,-2013 years on the 10th April in 2013；
3, product is used: A product is to repair condensation with the black Fructus Lycii moisturizing of the embodiment of the present invention 6 preparation,
B product is the product prepared by embodiment 3；
4, method of testing: after each group trier cleans face, respectively A, B product is spread upon left and right
Both sides facial skin, observes and investigates using effect；
5, test result statistics is as follows:
Table 2 A product service condition feedback conclusive table
Table 3 B product beta test situation feedback conclusive table
6, feedback conclusion:
Trier all represents that A product can not only moisturizing, moreover it is possible to skin care, improves skin quality, reduces microgroove,
There is no thick and heavy sense during use, there is no zest, and do not have allergic phenomena to occur.Institute is summed up by feedback in table
Showing, the people of 80% recommends product of the present invention.
Claims (11)
1. condensation is repaired in a black Fructus Lycii moisturizing, it is characterised in that: it is by following weight percentage
Supplementary material be prepared from:
Black Fructus Lycii moisturizing the most according to claim 1 repair condensation, it is characterised in that: it be by
The supplementary material of following weight percentage is prepared from:
Condensation is repaired in black Fructus Lycii moisturizing the most according to claim 1 and 2, it is characterised in that: institute
State the water extract that black Fructus Lycii extracting solution is black Fructus Lycii fruit powder.
Condensation is repaired in black Fructus Lycii moisturizing the most according to claim 3, it is characterised in that: Radix osteomelis schwerinais Chinese holly
The preparation method of Qi extracting solution is as follows: precision weighs the dried powder of 5g black Fructus Lycii, adds 50mL and goes
Ion distilled water, extracts 2 times in 50 DEG C of water-baths, and each 15 minutes, added water after filtration 100mL by residue
Extraction 2 times at 75 DEG C, each 15 minutes, extracting solution at merging 50 DEG C and 75 DEG C, filters, decompression
It is concentrated into 10g/mL, obtains black Fructus Lycii extracting solution.
Condensation is repaired in black Fructus Lycii moisturizing the most according to claim 1 and 2, it is characterised in that: ferment
The preparation method of female extracting solution is as follows: by beer yeast washing impurity-removing matter, de-hardship in 0-4 DEG C of water, then
Carry out coarse filtration, obtain the yeast slurry containing solid content, be subsequently adding accelerator, plasmolyticum and
NaOH, regulates pH to 6.0～7.0, and at a temperature of 52 DEG C ± 2 DEG C, self-dissolving is extracted 2-2.5 hour, then boils
Boiling, enzyme denaturing, cooling standing, centrifugation, removing cell wall fragments, vacuum-concentrcted to concentration is
10g/mL, obtains yeast extract.
Condensation is repaired in black Fructus Lycii moisturizing the most according to claim 1 and 2, it is characterised in that: sea
The preparation method of algae extracting solution is as follows: carried out by the dilute acid soln that Sargassum pH is 2～4 after the removal of impurity
Clean, rub, and grind homogenate in the dilute acid soln that pH is 2～4, then by the Sargassum after homogenate
Temperature 121～135 DEG C, ripening sterilizing 0.5～2 hours under pressure 1～5MPa, the Sargassum slurry after degraded
Add alkali and adjust pH to 5.0-7.0, the Sargassum serosity after adjusting inoculates the most cultured probiotics bacterial
Plant addition algin oligosaccharide in normal fermentation, then the serosity after fermentation to allocate, probiotic bacteria is entered
Row protection, propagation, be deployed into the serosity that concentration is 20g/mL, be seaweed extracted liquor.
Condensation is repaired in black Fructus Lycii moisturizing the most according to claim 1 and 2, it is characterised in that: honeybee
The preparation method of glue extracting solution is as follows: gone by propolis after the removal of impurity at a temperature of below-5 DEG C freezing
45h～52h, then by the propolis quick crashing after freezing, screening, adds ethanol by the propolis after screening
Solution impregnates 5h～7h at a temperature of 22 DEG C～26 DEG C, takes out the supernatant after then standing 1.5h～2.5h,
Remaining material adds ethanol solution again and continues dipping, stands, and so repeats at least three times, then merges each time
The supernatant obtained cools to less than 5 DEG C, filters, and filtrate carries out below 50 DEG C heating and steams
Sending out, being concentrated into concentration is 10g/mL, obtains propolis extract.
Condensation is repaired in black Fructus Lycii moisturizing the most according to claim 1, it is characterised in that: described guarantor
Humectant is selected from hyaluronic acid, allantoin, collagen protein, silk peptide, glycerol, 1,3 butylene glycol, Lubrajel CG
In one or more.
Condensation is repaired in black Fructus Lycii moisturizing the most according to claim 1, it is characterised in that: described
Solubilizing agent is selected from HPS, Cremophor RH40, PPG-1-PEG-9 Laurel glycol ethers, poly-second two
One or more in alcohol PEG-400, polyoxyethylated coconut oil alcohol-7.
Condensation is repaired in black Fructus Lycii moisturizing the most according to claim 1 and 2, it is characterised in that:
Described antibacterial is in Kathon CG, Germall II, Germall Plus, Glydant PLUS
One or more.
The preparation method of condensation is repaired in black Fructus Lycii moisturizing described in 11. claim 1, it is characterised in that
It includes following operating procedure:
(1) raw material is weighed by weight ratio；
(2) taking Acritamer 940 to add water 80 DEG C ± 5 DEG C stirring and dissolving, being made into concentration is 2%g/ml's
Colloid solution is standby；
(3) by wetting agent, methyl hydroxybenzoate, disodiumedetate, solubilizing agent and water at 70～90 DEG C
Lower fully dissolving, forms the solution A of transparent clarification；
(4) colloid solution, triethanolamine are joined in solution A, at 60～80 DEG C, continue stirring
It is uniformly dissolved, forms clear gum mixture；
(5) when said mixture is cooled to 40～50 DEG C, add antibacterial, black Fructus Lycii extracting solution,
Yeast extract, seaweed extracted liquor, propolis extract and essence, stir, and obtains black Fructus Lycii and protects
Wet reparation condensation.
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| CN104434741A (en) * | 2014-12-23 | 2015-03-25 | 吴辰 | Black wolfberry facial mask |
| CN105193700A (en) * | 2015-10-31 | 2015-12-30 | 代秀梅 | Anti-freckle enzyme cream |
| CN105232441A (en) * | 2015-10-31 | 2016-01-13 | 代秀梅 | Preparing method of enzyme speckle removing cream |
| CN105193692A (en) * | 2015-10-31 | 2015-12-30 | 代秀梅 | Application of enzyme cream |
| CN105193701A (en) * | 2015-10-31 | 2015-12-30 | 代秀梅 | Use method of anti-freckle enzyme cream |
| CN106038464A (en) * | 2016-07-11 | 2016-10-26 | 佛山杰致信息科技有限公司 | Composite anti-wrinkle skin care product and preparation method thereof |
| CN107822945A (en) * | 2017-09-28 | 2018-03-23 | 杭州惠博士健康产业有限公司 | One kind is matched unartificial yeast composition, preparation method and applied in cosmetics |
| CN109172433B (en) * | 2018-10-12 | 2020-08-07 | 广州市科能化妆品科研有限公司 | Long-acting moisturizing composition and application thereof in cosmetics |
| CN109820807A (en) * | 2019-04-11 | 2019-05-31 | 易志 | A kind of moisturizing restorative facial cream and preparation method thereof |
| CN115607586A (en) * | 2020-04-24 | 2023-01-17 | 珠海岐微生物科技有限公司 | Application of dandelion and monomer compound thereof in mite killing |
| CN111643437A (en) * | 2020-07-22 | 2020-09-11 | 宁夏志超科技有限公司 | Formula and preparation method of facial mask containing lycium ruthenicum essence |
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| CN101991709A (en) * | 2010-11-09 | 2011-03-30 | 中国科学院西北高原生物研究所 | Method for preparing antioxidant lycium ruthenicum extract |
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