CN108685097B - Application of iris angulatus in anti-aging - Google Patents

Application of iris angulatus in anti-aging Download PDF

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CN108685097B
CN108685097B CN201810219805.3A CN201810219805A CN108685097B CN 108685097 B CN108685097 B CN 108685097B CN 201810219805 A CN201810219805 A CN 201810219805A CN 108685097 B CN108685097 B CN 108685097B
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iris
aging agent
aging
fruits
angulatus
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CN108685097A (en
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薛长松
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Tonghua guozhenbufan Technology Development Co.,Ltd.
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Tonghua Normal University
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/09—Mashed or comminuted products, e.g. pulp, purée, sauce, or products made therefrom, e.g. snacks
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3562—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention discloses application of iris diaphragm in anti-aging, which is to directly prepare iris diaphragm anti-aging agent from iris diaphragm fruits, protoplasm or processed iris diaphragm; or the iris angulatus fruits, the original pulp or the processed iris angulatus are used together with other raw materials or auxiliary materials to prepare the iris angulatus anti-aging agent which is used as an anti-aging agent for drinks and foods, medicaments, medicines and cosmetics. The drinks and foods are any approved product types, including common foods, functional foods and the like; the medicine or medicament is any approved product formulation, including granules, tablets, medicinal granules, soft capsules, dripping pills, ointments, injections and the like; the cosmetic is in any acceptable form, including cream, emulsion, facial film, etc. The beneficial effects are that: the anti-aging agent has good anti-aging effect, can keep the nutritional components of the iris angulatus, has the characteristics of stable system, difficult moisture absorption and deliquescence, and has long shelf life.

Description

Application of iris angulatus in anti-aging
Technical Field
The invention relates to application of iris angulatus in food, in particular to application of iris angulatus in anti-aging.
Background
The biological aging process is a multidimensional topic, and the organism aging process of an organism can be embodied in normal organism physiological functions and organism tissues, cells and molecular changes, and can also be embodied in a series of organism aging related diseases such as osteoporosis, cancer and the like. The aging process is influenced by genetic genes and external environmental factors, and scientific research proves that the external factors can delay the organism aging process of organisms.
Cypress of yellow mushroom is of Solanaceae (Solanaceae) Fruits of Physalis pubescens L, also called as Physalis pubescens, sweet mushroom, agaricus, pineapple and calyx, annual herbaceous plants are mainly distributed in northeast China, especially in Heilongjiang province with highest yield, mature in summer and autumn and long storage time. The ripe fruits of the pholiota nivea are orange yellow, can be directly eaten after the persistent calyx is removed, have sour and sweet taste and rich nutrition, are suitable for all ages, and are popular current fruits in northeast China.
The iris tectorum contains more than 20 mineral substances and trace elements such as abundant vitamin C, carotenoid, calcium, iron, selenium and the like, contains 18 amino acids required by a human body, accounts for 31 percent of the total amount of the amino acids, wherein the content of aspartic acid and leucine is high, and the iris tectorum also contains abundant carbohydrate components, sterols, alkaloids, lipids, organic acids and the like, and has a very good health care function. The organic acids such as tartaric acid, malic acid and citric acid contained in the iris angulatus make the berries of the iris angulatus have a unique sweet and sour taste and have the function of promoting appetite. The seed oil of iris angulatus contains unsaturated fatty acids essential to the human body, and is composed of linoleic acid, oleic acid, palmitic acid, and stearic acid. The flavous mushroom quamoclit fruit can be used as a medicine, is considered by the traditional Chinese medicine to have sour and mild nature and taste, enter lung channels, have the effects of clearing heat and removing toxicity, promoting urination and stopping bleeding, and is one of the raw materials of Chinese patent medicines such as physalis alkekengi cough relieving liquid, golden lantern antiphlogistic, ruby trauma paste and the like. The quamoclit angulatus fruit contains abundant bioactive components, such as flavonoids, physalins, carotenoids, physalin A and B, and has antibacterial, antitumor, fatigue relieving, muscle pain relieving, blood pressure lowering, wound healing promoting, and arteriosclerosis and cardiovascular diseases preventing effects.
At present, the iris diaphragm as a characteristic resource is popular with people, and a series of foods such as drinks, fruit wine, fruit vinegar, preserved fruits, jelly and the like are developed by using the iris diaphragm as a raw material, and the foods are deeply favored by mass consumers by utilizing the nutrition and delicious characteristics of the iris diaphragm and have huge market and wide development prospect. In addition, the anti-oxidation health-care food of the iris angulatus is also applied and developed, and preliminary research is carried out on chemical components of the iris angulatus. At present, however, the role of iris diaphragm in the senescence of organisms, and in particular in the slowing or resistance of the biological senescence process as judged by the detection of the senescence-associated biomarker β -galactosidase activity, is not known at all.
The advantages of zebrafish as a novel model animal are gradually recognized, and the central nervous system, internal organs, blood and visual system of zebrafish are 87% homologous to human at the gene level, and the early development is very similar to human, and the zebrafish is the best model organism for researching related disease genes. Internationally, the use of zebrafish-model organisms is gradually expanding and deepening in the research of development, functions and diseases (e.g., neurodegenerative diseases, hereditary cardiovascular diseases, diabetes, etc.) of various systems (e.g., nervous system, cardiovascular system, immune system, etc.) of a living body, has been successfully used for the scale new drug screening of small molecule compounds, and has been successfully marketed. Scholars at home and abroad develop a plurality of researches on aging biology related researches and anti-aging efficacy evaluation by using zebra fish, the SA-beta-Gal positive rate can well reflect the aging speed of cell groups or individual tissues, and the SA-beta-Gal positive rate is an important biological index for reflecting the aging degree and is widely applied to anti-aging mechanism researches and efficacy evaluation researches at home and abroad.
Disclosure of Invention
The invention aims to provide an application of iris diaphragm in anti-aging, which is prepared from iris diaphragm fruits, raw pulp or processed iris diaphragm into an anti-aging agent with stable system and difficult moisture absorption and deliquescence, and the anti-aging agent can be used in drinks and foods, medicaments, medicines and cosmetics and meets the requirements of people with anti-aging.
Aiming at the problems mentioned in the technology, the invention adopts the technical scheme that:
the application of the iris diaphragm in anti-aging is that the iris diaphragm fruits, raw pulp or processed iris diaphragms are directly prepared into an anti-aging agent; or the iris angulatus fruits, the original pulp or the processed iris angulatus are used together with other raw materials or auxiliary materials to prepare the iris angulatus anti-aging agent which is used as an anti-aging agent for drinks and foods. The food and drink is any kind of approved product, including general food, functional food, and the like.
The application of the iris diaphragm in anti-aging is that the iris diaphragm fruits, raw pulp or processed iris diaphragms are directly prepared into an anti-aging agent; or the iris angulatus fruits, the original pulp or the processed iris angulatus are used together with other raw materials or auxiliary materials to prepare the iris angulatus anti-aging agent which is used as an anti-aging agent for medicines and medicaments. The medicine or medicament is any approved product formulation, including granules, tablets, medicinal granules, soft capsules, dripping pills, ointments, injections and the like.
The application of the iris diaphragm in anti-aging is that the iris diaphragm fruits, raw pulp or processed iris diaphragms are directly prepared into an anti-aging agent; or the iris angulatus fruits, the original pulp or the processed iris angulatus are used together with other raw materials or auxiliary materials to prepare the iris angulatus anti-aging agent which is used in cosmetics as an anti-aging agent. The cosmetic is in any acceptable form, including cream, emulsion, facial film, etc.
Preferably, the pleurotus citrinopileatus protoplasm anti-aging agent comprises the following components in parts by weight: 1-5 parts of physalis pubescens fruit primary pulp, 0-1 part of mannitol, 0-0.5 part of Chinese rose stem cells, 0-1 part of wolfberry extract and 0-1 part of sea buckthorn extract. The effective components in the anti-aging agent can be mutually increased, so that the anti-aging agent can reduce oxidation pressure, provide nutrition or energy factors, maintain the reduction state of cells and delay aging; has strong oxidation resistance, can remove free radicals in organisms, reduce peroxide oxygen and lipid peroxide, can be combined with membrane lipid bilayer molecules to protect cells, is prevented from being damaged by free radicals inside and outside the cells, and can prevent and treat diseases related to aging such as obstructive atherosclerosis, coronary heart disease, apoplexy and the like; it has effects in inhibiting activity of melanogenesis enzyme, preventing skin aging and pigmentation, improving skin oxidation resistance, improving skin luster, and delaying skin aging.
More preferably, the mannitol contains 1.2-1.5% of levo-mannitol, and the levo-mannitol can cooperate with homogenization to release more soluble saccharide substances in the Huanggu quan, increase the content of soluble solid substances in the fruit juice, destroy the viscosity network structure of the pulp, enhance the ability of particles to bind water, improve the suspension stability of the Huanggu quan fruit pulp, increase the glass transition temperature of the pulp, reduce the reaction of heat-sensitive substances such as vitamin C, and the like, maintain the nutrient components of the Huanggu quan, make the obtained Huanggu quan anti-aging agent difficult to absorb moisture and deliquesce, maintain the moisture of the Huanggu quan anti-aging agent, and prolong the shelf life of the Huanggu quan anti-aging agent.
Preferably, the preparation method of the pleurotus citrinopileatus primary pulp anti-aging agent comprises the following steps:
inactivating enzyme: boiling cleaned iris diaphragm fruits in boiling water for 5-15min according to the material-liquid ratio of 1:1-2, taking out and cooling to room temperature to obtain the enzyme-inactivated iris diaphragm fruits for later use, wherein the step can destroy the activities of pectinase and oxidase in the iris diaphragm fruits, inhibit enzymatic browning and degradation of pectin substances, prevent phenols from being oxidized into quinones under aerobic conditions, further form melanin and melanoid, have the function of color protection, soften the tissue of the iris diaphragm fruits and facilitate pulping treatment;
pulping: adding isomaltulose alcohol 0.023-0.028% of the weight of the flavipidemia iris fruits and erythritol 0.013-0.016% of the weight of the flavipidemia iris fruits into the enzyme inactivated flavipidemia fruits, grinding by using a colloid mill with the emulsification fineness of 2-50 mu m, adding mannitol, homogenizing at the temperature of 40-50 ℃ and the pressure of 20-30MPa to obtain flavipidemic pulp, filtering, adjusting the solid content of the filtrate to be 0.125-0.25mg/mL to obtain the flavipidemic pulp, wherein the homogenization can generate the effects of impacting, blasting, shearing force and the like on large granular substances such as fat, fiber, protein and the like in pulp, so that the particle diameter can be reduced, the volume and the mass of single particles can be reduced, the particles can be dispersed, the fat spheres can be refined, the problems of fat sphere suspension and large granular flocculation substances can be solved, and the suspension stability of the flavipidemic pulp can be improved, the components in the obtained anti-aging agent are uniformly distributed, and the isomaltitol and the erythritol are mutually matched, so that the viscosity network structure of the pulp can be destroyed, the binding capacity of pulp particles and water is enhanced, the viscosity of the pulp is reduced, and the stability of the anti-aging agent is improved;
preparing an anti-aging agent: the anti-aging agent is prepared by uniformly mixing physalis pubescens protoplasm, Chinese rose stem cells, a wolfberry fruit extract and a sea buckthorn extract according to the formula amount, wherein the active ingredients in the anti-aging agent can be mutually gained, and the metabolic network and the cell communication network in the aging process of an organism can be adjusted and controlled through hormones, cytokines, various signal transmission and the like, so that the anti-aging agent has an obvious anti-aging effect, has obvious medicinal health-care functions of resisting inflammation, resisting biological oxidation, reducing blood fat, enhancing the immunity of the organism and the like, is used for drinks and foods, medicaments and cosmetics and can meet the requirements of anti-aging people.
Compared with the prior art, the invention has the advantages that: 1) application of the iris angulatus in anti-aging, iris angulatus fruits, raw pulp or processed iris angulatus are prepared into an anti-aging agent, and the anti-aging agent is used in drinks and foods, medicaments, medicines and cosmetics and can meet the requirements of anti-aging people; 2) the anti-aging agent has the advantages that the effective components in the anti-aging agent can be mutually gained, the metabolic network and the cell communication network in the aging process of the organism can be adjusted and controlled through hormone, cell factors, various signal transmission and the like, the anti-aging agent has obvious anti-aging effect, and simultaneously has obvious medicinal health care functions of resisting inflammation, resisting biological oxidation, reducing blood fat, enhancing the immunity of the organism and the like; 3) the antiaging agent can maintain nutritional components of Cyamopsis angulatus, has stable system, is not prone to moisture absorption and deliquescence, and has long shelf life.
Drawings
FIG. 1 is a collected image of SA- β -gal staining of zebrafish according to example 6 of the present invention.
Detailed Description
The scheme of the invention is further illustrated by the following examples:
example 1:
the application of the iris angulatus in anti-aging is that iris angulatus protoplasm is used together with other raw materials or auxiliary materials to prepare the iris angulatus anti-aging agent which is used as an anti-aging agent in drinks and foods. The food and drink is any kind of approved product, including general food, functional food, and the like.
The application of the iris angulatus in anti-aging is that iris angulatus protoplasm is used together with other raw materials or auxiliary materials to prepare the iris angulatus anti-aging agent which is used as an anti-aging agent for medicines and medicaments. The medicine or medicament is any approved product formulation, including granules, tablets, medicinal granules, soft capsules, dripping pills, ointments, injections and the like.
The application of the iris angulatus in anti-aging is that iris angulatus protoplasm is used together with other raw materials or auxiliary materials to prepare the iris angulatus anti-aging agent which is used as an anti-aging agent in cosmetics. The cosmetic is in any acceptable form, including cream, emulsion, facial film, etc.
The pleurotus citrinopileatus protoplasm anti-aging agent comprises the following components in parts by weight: 5 parts of physalis pubescens fruit primary pulp, 1 part of mannitol, 0.4 part of Chinese rose stem cells, 0.2 part of wolfberry extract and 0.8 part of sea buckthorn extract. The effective components in the anti-aging agent can be mutually increased, so that the anti-aging agent can reduce oxidation pressure, provide nutrition or energy factors, maintain the reduction state of cells and delay aging; has strong oxidation resistance, can remove free radicals in organisms, reduce peroxide oxygen and lipid peroxide, can be combined with membrane lipid bilayer molecules to protect cells, is prevented from being damaged by free radicals inside and outside the cells, and can prevent and treat diseases related to aging such as obstructive atherosclerosis, coronary heart disease, apoplexy and the like; it has effects in inhibiting activity of melanogenesis enzyme, preventing skin aging and pigmentation, improving skin oxidation resistance, improving skin luster, and delaying skin aging.
The mannitol contains 1.2% of levo-mannitol, and the levo-mannitol can cooperate with homogenization to release more soluble saccharide substances in the Huanggu quan, increase the content of soluble solid matters in fruit juice, destroy the network structure of pulp viscosity, enhance the binding capacity of particles and water, improve the suspension stability of Huanggu quan fruit puree, increase the vitrification conversion temperature of the puree, reduce the reaction of heat-sensitive substances such as vitamin C, maintain the nutrient components of the Huanggu quan, prevent moisture absorption and deliquescence of the obtained Huanggu quan anti-aging agent, maintain the moisture of the Huanggu quan anti-aging agent and prolong the shelf life of the Huanggu quan anti-aging agent.
Preferably, the preparation method of the pleurotus citrinopileatus primary pulp anti-aging agent comprises the following steps:
1) inactivating enzyme: boiling cleaned iris diaphragm fruits in boiling water for 15min according to a material-liquid ratio of 1:1, taking out the boiled fruits, cooling the boiled fruits to room temperature to obtain the enzyme-inactivated iris diaphragm fruits for later use, wherein the step can destroy activities of pectinase and oxidase in the iris diaphragm fruits, inhibit enzymatic browning and degradation of pectin substances, prevent phenols from being oxidized into quinone substances under aerobic conditions, further form melanin and melanoid, have a color protection function, soften iris diaphragm fruit tissues and facilitate pulping;
2) pulping: adding isomaltulose alcohol 0.023% of the weight of the iris angulatus fruits and erythritol 0.016% of the weight of the iris angulatus fruits into enzyme inactivated iris angulatus fruits, grinding by using a colloid mill with the emulsification fineness of 2-50 mu m, adding mannitol, homogenizing at the temperature of 40 ℃ and the pressure of 30MPa to obtain phytin fruit puree, filtering, adjusting the solid content of the filtrate to be 0.125mg/mL to obtain the phytin puree, wherein the homogenization can generate the effects of impacting, blasting, shearing force and the like on large granular substances such as fat, fiber, protein and the like in pulp, reduce the particle diameter, reduce the volume and the mass of single particles, disperse the particles, refine the fat spheres, solve the problems of fat sphere suspension and large granular substance flocculation and sedimentation, improve the suspension stability of the phytin fruit puree, and uniformly distribute the components in the obtained phytin freeze-dried fruit cores, the isomaltitol and the erythritol are matched with each other, so that the viscosity network structure of the pulp can be destroyed, the binding capacity of pulp particles and water is enhanced, the viscosity of the pulp is reduced, and the stability of a pulp system is improved;
3) preparing an anti-aging agent: the anti-aging agent is prepared by uniformly mixing physalis pubescens protoplasm, Chinese rose stem cells, a wolfberry fruit extract and a sea buckthorn extract according to the formula amount, wherein the active ingredients in the anti-aging agent can be mutually gained, and the metabolic network and the cell communication network in the aging process of an organism can be adjusted and controlled through hormones, cytokines, various signal transmission and the like, so that the anti-aging agent has an obvious anti-aging effect, has obvious medicinal health-care functions of resisting inflammation, resisting biological oxidation, reducing blood fat, enhancing the immunity of the organism and the like, is used for drinks and foods, medicaments and cosmetics and can meet the requirements of anti-aging people.
Example 2:
the application of the iris angulata in anti-aging is to prepare iris angulata protoplasm into an anti-aging agent, and the anti-aging agent is used in drinks and foods, medicaments and cosmetics.
The pleurotus citrinopileatus protoplasm anti-aging agent comprises the following components in parts by weight: physalis pubescens fruit puree.
The preparation method of the pleurotus citrinopileatus primary pulp anti-aging agent comprises the following steps:
1) inactivating enzyme: boiling cleaned iris angulatus fruits in boiling water for 10min according to the material-liquid ratio of 1:1.5, taking out, cooling to room temperature to obtain the iris angulatus fruits with enzyme inactivated for later use;
2) pulping: adding isomaltulose alcohol accounting for 0.025 percent of the weight of the annulated flavedo iris fruits and erythritol accounting for 0.015 percent of the weight of the flavedo iris fruits into the enzymatically inactivated flavedo iris fruits, grinding by using a colloid mill with the emulsification fineness of 2-50 mu m, adding mannitol, homogenizing at the temperature of 45 ℃ and under the pressure of 25MPa to obtain flavedo fruit puree, filtering, and adjusting the solid content concentration of a filtrate to be 0.15mg/mL to obtain the flavedo puree anti-aging agent.
Example 3:
the application of the iris angulata in anti-aging is that iris angulata protoplasm is used together with other raw materials or auxiliary materials to prepare the iris angulata anti-aging agent which is used as an anti-aging agent for drinks and foods, medicaments, medicines and cosmetics.
The pleurotus citrinopileatus protoplasm anti-aging agent comprises the following components in parts by weight: 3 parts of physalis pubescens fruit primary pulp, 0.3 part of mannitol, 0.2 part of Chinese rose stem cells, 0.5 part of wolfberry extract and 0.5 part of sea buckthorn extract. The mannitol contains 1.4% of L-mannitol.
The preparation method of the pleurotus citrinopileatus primary pulp anti-aging agent comprises the following steps:
1) inactivating enzyme: boiling cleaned iris angulatus fruits in boiling water for 10min according to the material-liquid ratio of 1:1.5, taking out, cooling to room temperature to obtain the iris angulatus fruits with enzyme inactivated for later use;
2) pulping: adding isomaltulose alcohol accounting for 0.025 percent of the weight of the annulated flavedo iris fruits and erythritol accounting for 0.015 percent of the weight of the flavedo iris fruits into the enzymatically inactivated flavedo iris fruits, grinding by using a colloid mill with the emulsification fineness of 2-50 mu m, adding mannitol, homogenizing at the temperature of 45 ℃ and the pressure of 25MPa to obtain flavedo fruit primary pulp, filtering, and adjusting the solid content concentration of a filtrate to be 0.15mg/mL to obtain the flavedo primary pulp;
3) preparing an anti-aging agent: uniformly mixing physalis pubescens protoplasm, Chinese rose stem cells, a medlar extract and a sea buckthorn extract according to the formula amount to obtain the anti-aging agent.
Example 4:
the application of the iris angulatus in anti-aging is to directly prepare the iris angulatus fruits into an anti-aging agent for drinks and foods.
The anti-aging agent for the cyprocodiolus angulatus fruits comprises the following components in parts by weight: physalis pubescens fruit.
The preparation method of the anti-aging agent for the cyprocolic angulatus fruits comprises the following steps:
step 1: boiling cleaned iris diaphragm fruits in boiling water for 10min according to the material-liquid ratio of 1:1.5, taking out the boiled fruits, cooling to room temperature to obtain the enzyme-inactivated iris diaphragm fruits for later use, wherein the step can destroy the activities of pectinase and oxidase in the iris diaphragm fruits, inhibit enzymatic browning and degradation of pectin substances, prevent phenolic substances from being oxidized into quinone substances under aerobic conditions, further form melanin and melanoid, and have the function of color protection;
step 2: peeling the quamoclit quanikoe fruits, spreading the quamoclit quanikoe fruits in a freezing tray, pre-freezing for 5 hours at the temperature of minus 50 ℃, vacuumizing until the vacuum degree is 65Pa, heating to 20 ℃ at the temperature heating rate of 5 ℃/h, and drying for 5 hours to obtain the physalis alkekengi fruit anti-aging agent. The anti-aging agent for the physalis alkekengi fruits obtained by freezing and vacuum drying in the step has low water content, can keep nutritional components such as cyprotes iris color, fruit fragrance, vitamin C and the like, inhibits the growth of microorganisms and the action of enzymes, and protects easily-oxidizable substances.
Example 5:
the application of the processed iris angulatus in anti-aging is to directly prepare the processed iris angulatus into an anti-aging agent, and the anti-aging agent is used in drinks and foods.
The anti-aging agent comprises the following components in parts by weight: processed iris tectorum.
The preparation method of the anti-aging agent comprises the following steps:
1) inactivating enzyme: boiling cleaned iris angulatus fruits in boiling water for 10min according to the material-liquid ratio of 1:1.5, taking out, cooling to room temperature to obtain the iris angulatus fruits with enzyme inactivated for later use;
2) pulping: adding isomaltulose alcohol accounting for 0.025 percent of the weight of the annulated flavedo iris fruits and erythritol accounting for 0.015 percent of the weight of the flavedo iris fruits into the enzymatically inactivated flavedo iris fruits, grinding by using a colloid mill with the emulsification fineness of 2-50 mu m, adding mannitol, homogenizing at the temperature of 45 ℃ and the pressure of 25MPa to obtain flavedo fruit puree, filtering, placing the filtrate in a freezing disc, and then placing in a vacuum freezing dryer with the vacuum degree of 1.2mbar and the temperature of-50 ℃ for vacuum freezing and drying to obtain the flavedo puree freeze-dried powder anti-aging agent.
Example 6:
testing the anti-aging performance of physalis pubescens:
the test group dosing solutions were: test group a was the anti-aging agent of example 2, test group B was 7-fold diluted, test group C was 9-fold diluted, and test group D was 11-fold diluted, respectively, with the anti-aging agent of example 2; the blank group dosing solution was: and (4) distilled water.
Zebra fish SA-beta-gal staining experiment:
the anti-aging agent in example 2 is diluted by distilled water according to multiple times, and zebra fish experimental animal sample breeding, each group administration and SA-beta-gal staining experiments are carried out.
Testing the anti-aging performance of physalis pubescens: after the zebra fish in the test group or the blank group is dyed, an image is captured and collected by a microscope, all the images uniformly adopt the same shooting parameters including body position, magnification factor, light intensity, absorbance, exposure setting (each sample is respectively exposed for 5ms, 15ms and 30ms, three pictures are shot), and the like, the collected image of the zebra fish SA-beta-gal dyeing effect is shown in figure 1, and microscopic imaging shows that after the test group is respectively treated by anti-aging agents with different concentrations, compared with the blank control group, the positive rate of the zebra fish SA-beta-gal dyeing is visually reduced.
To ensure comparability, lateral fish volume area values (S) and integrated stain optical density values (IOD) were then obtained separately using Image analysis soft Image Pro Plus, and the ratio IOD/S calculated as shown in table 1.
TABLE 1 IOD/S results of SA-beta-gal staining of zebrafish treated with different concentrations of anti-aging agent
Figure 397832DEST_PATH_IMAGE001
As shown in Table 1, the test group showed a low positive rate of SA-. beta. -gal staining compared with the blank group, and the difference was statistically significant (P < 0.05). The anti-aging agent can reduce the staining positive rate of SA-beta-gal staining of the zebra fish under a proper proportion concentration, and can effectively intervene the aging of embryonic developmental cells of the zebra fish and delay the aging process of the zebra fish, thereby proving that the flavous iris has anti-aging effect.
Conventional operations in the operation steps of the present invention are well known to those skilled in the art and will not be described herein.
The embodiments described above are intended to illustrate the technical solutions of the present invention in detail, and it should be understood that the above-mentioned embodiments are only specific embodiments of the present invention, and are not intended to limit the present invention, and any modification, supplement or similar substitution made within the scope of the principles of the present invention should be included in the protection scope of the present invention.

Claims (3)

1. The application of the cyprodinil slab in preparing an anti-aging product is characterized in that: preparing the iris diaphragm protoplasm or the processed iris diaphragm into an anti-aging agent used as an anti-aging agent for drinks and foods;
the preparation method of the cypress quamoclit protoplasm comprises the following steps: 1) inactivating enzyme: boiling cleaned iris angulatus fruits in boiling water for 5-15min according to the material-liquid ratio of 1:1-2, taking out, cooling to room temperature to obtain the enzyme inactivated iris angulatus fruits for later use; 2) pulping: adding isomaltulose alcohol accounting for 0.023-0.028% of the weight of the Amurelit iris fruits and erythritol accounting for 0.013-0.016% of the weight of the Amurelit iris fruits into the enzyme inactivated Amurelit iris fruits, grinding by using a colloid mill with the emulsification fineness of 2-50 mu m, adding mannitol, homogenizing at the temperature of 40-50 ℃ and the pressure of 20-30MPa to obtain a physalis alkekengi fruit primary pulp, filtering, and adjusting the solid content of a filtrate to be 0.125-0.25mg/mL to obtain the physalis alkekengi primary pulp;
the preparation method of the processed iris diaphragm comprises the following steps: and filtering the iris diaphragm protoplasm, and carrying out vacuum freeze drying on the filtrate to obtain the processed iris diaphragm.
2. Use of iris diaphragm according to claim 1 in the preparation of an anti-ageing product, characterised in that: the application is to use the pholiota angulata anti-aging agent in medicines and medicaments.
3. Use of iris diaphragm according to claim 1 in the preparation of an anti-ageing product, characterised in that: the application is to use the pholiota angulata anti-aging agent in cosmetics.
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