CN101990433B - 提高Atoh1表达的化合物 - Google Patents
提高Atoh1表达的化合物 Download PDFInfo
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- CN101990433B CN101990433B CN200980112358.0A CN200980112358A CN101990433B CN 101990433 B CN101990433 B CN 101990433B CN 200980112358 A CN200980112358 A CN 200980112358A CN 101990433 B CN101990433 B CN 101990433B
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- 0 CCC(C(C)C1C2)=C(C)*C1=CC2c1ccc(*)cc1 Chemical compound CCC(C(C)C1C2)=C(C)*C1=CC2c1ccc(*)cc1 0.000 description 2
- XNYPCDIWVSCQDN-UHFFFAOYSA-N CC(C)(C)c(cc1)ccc1C(SC1C(C)=O)=CC1N Chemical compound CC(C)(C)c(cc1)ccc1C(SC1C(C)=O)=CC1N XNYPCDIWVSCQDN-UHFFFAOYSA-N 0.000 description 1
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2703208P | 2008-02-07 | 2008-02-07 | |
| US61/027,032 | 2008-02-07 | ||
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| WO2009100438A2 (en) | 2009-08-13 |
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| CA2714370C (en) | 2017-05-02 |
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| AU2009212135B2 (en) | 2014-08-21 |
| US9433610B2 (en) | 2016-09-06 |
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| HK1155652A1 (en) | 2012-05-25 |
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| JP5749829B2 (ja) | 2015-07-15 |
| EP2732819A2 (en) | 2014-05-21 |
| EP2254572B1 (en) | 2013-10-16 |
| CN101990433A (zh) | 2011-03-23 |
| US20090232780A1 (en) | 2009-09-17 |
| US8188131B2 (en) | 2012-05-29 |
| US20150157607A1 (en) | 2015-06-11 |
| US11160808B2 (en) | 2021-11-02 |
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| US10406163B2 (en) | 2019-09-10 |
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| EP2254572A2 (en) | 2010-12-01 |
| US20120328580A1 (en) | 2012-12-27 |
| AU2009212135A1 (en) | 2009-08-13 |
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