CN101970679B - 氨基转移酶和氧化还原酶核酸和多肽和使用方法 - Google Patents

氨基转移酶和氧化还原酶核酸和多肽和使用方法 Download PDF

Info

Publication number
CN101970679B
CN101970679B CN200880127576.7A CN200880127576A CN101970679B CN 101970679 B CN101970679 B CN 101970679B CN 200880127576 A CN200880127576 A CN 200880127576A CN 101970679 B CN101970679 B CN 101970679B
Authority
CN
China
Prior art keywords
seq
dat
monatin
polypeptide
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200880127576.7A
Other languages
English (en)
Chinese (zh)
Other versions
CN101970679A (zh
Inventor
M·L.·德苏扎
P·M.·希克斯
S·R.·科尔曼
J·M.·拉普拉萨
J·M.·伦多尔夫
S·C.·麦克法伦
E·马拉斯科
牛伟
F·A.·桑切斯-列拉
C·索尔海德
D·P.·魏纳
P·卢京比尔
A·布埃诺
J·昆卡
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cargill Inc
Original Assignee
Cargill Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cargill Inc filed Critical Cargill Inc
Publication of CN101970679A publication Critical patent/CN101970679A/zh
Application granted granted Critical
Publication of CN101970679B publication Critical patent/CN101970679B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN200880127576.7A 2008-01-03 2008-12-31 氨基转移酶和氧化还原酶核酸和多肽和使用方法 Expired - Fee Related CN101970679B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1881408P 2008-01-03 2008-01-03
US61/018,814 2008-01-03
PCT/US2008/014137 WO2009088482A1 (en) 2008-01-03 2008-12-31 Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using

Publications (2)

Publication Number Publication Date
CN101970679A CN101970679A (zh) 2011-02-09
CN101970679B true CN101970679B (zh) 2015-04-22

Family

ID=40853332

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880127576.7A Expired - Fee Related CN101970679B (zh) 2008-01-03 2008-12-31 氨基转移酶和氧化还原酶核酸和多肽和使用方法

Country Status (8)

Country Link
US (1) US8785162B2 (https=)
EP (1) EP2225390A4 (https=)
JP (2) JP5683962B2 (https=)
CN (1) CN101970679B (https=)
AU (1) AU2008347048B2 (https=)
BR (1) BRPI0822219A2 (https=)
CA (1) CA2726928A1 (https=)
WO (1) WO2009088482A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US7572607B2 (en) * 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
WO2005014839A2 (en) * 2003-08-01 2005-02-17 Cargill, Incorporated Monatin tabletop sweetener compositions and methods of making same
WO2005016022A1 (en) * 2003-08-14 2005-02-24 Cargill, Incorporated Chewing gum compositions comprising monatin and methods of making same
WO2005020721A1 (en) * 2003-08-25 2005-03-10 Cargill, Incorporated Beverage compositions comprising monatin and methods of making same
EP1678313B1 (en) * 2003-10-21 2011-02-16 Cargill, Incorporated Production of monatin and monatin precursors
US8153405B2 (en) * 2005-04-20 2012-04-10 Cargill, Incorporated Products and methods for in vivo secretion of monatin
US8158389B2 (en) * 2005-04-20 2012-04-17 Cargill, Incorporated Products and methods for in vivo secretion of monatin
US8076108B2 (en) 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
MX2008011477A (es) * 2006-03-07 2008-09-23 Cargill Inc Aldolasas, acidos nucleicos que las codifican y metodos para hacerlas y usarlas.
US20090198072A1 (en) * 2006-05-24 2009-08-06 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions
US10332562B2 (en) * 2007-04-17 2019-06-25 Sirius-Beta Corporation System and method for space-time annotation-capable media scrubbing
US8367847B2 (en) * 2007-10-01 2013-02-05 Cargill, Incorporated Production of monatin enantiomers
US8003361B2 (en) * 2007-10-01 2011-08-23 Cargill Incorporated Production of monatin enantiomers
US8076107B2 (en) * 2007-10-01 2011-12-13 Cargill, Incorporated Production of monatin stereoisomers
CN104651381A (zh) 2008-01-03 2015-05-27 巴斯夫酶有限责任公司 转移酶和氧化还原酶、编码它们的核酸以及其制备和应用方法
US9029113B2 (en) * 2011-03-11 2015-05-12 Kaneka Corporation Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same
EP2704736A4 (en) 2011-03-30 2016-07-20 Univ Texas METHOD AND COMPOSITIONS FOR TARGETING ADIPOSE CELLS IN MAMMALS
US9617573B2 (en) * 2013-02-28 2017-04-11 Codexis, Inc. Engineered transaminase polypeptides for industrial biocatalysis
US11191555B2 (en) 2017-05-12 2021-12-07 Covidien Lp Retrieval of material from vessel lumens
CN119264211A (zh) 2018-08-27 2025-01-07 瑞泽恩制药公司 拉曼光谱在下游纯化中的应用
WO2020185971A1 (en) 2019-03-11 2020-09-17 Aldevron, Llc Growing bacterial host cells in gas-permeable low-density polyethylene bags to produce plasmid dna or recombinant molecules
KR20240067118A (ko) * 2021-09-29 2024-05-16 아이오니스 파마수티컬즈, 인코포레이티드 접합된 올리고뉴클레오타이드 및 이의 용도
CN114317629B (zh) * 2021-12-31 2024-08-27 山西大学 一种转氨酶连续化反应制备手性胺的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007133183A2 (en) * 2006-04-26 2007-11-22 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099848A (en) * 1997-11-18 2000-08-08 The Trustees Of The University Of Pennsylvania Immunogenic compositions comprising DAL/DAT double-mutant, auxotrophic, attenuated strains of Listeria and their methods of use
US7572607B2 (en) * 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
PL208481B1 (pl) * 2002-04-23 2011-05-31 Cargill Sposób wytwarzania monatyny
WO2004085624A2 (en) * 2003-03-24 2004-10-07 Diversa Corporation Transaminases, deaminases and aminomutases and compositions and methods for enzymatic detoxification
WO2005020721A1 (en) * 2003-08-25 2005-03-10 Cargill, Incorporated Beverage compositions comprising monatin and methods of making same
US8076108B2 (en) 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
WO2007140195A2 (en) 2006-05-24 2007-12-06 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007133183A2 (en) * 2006-04-26 2007-11-22 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Also Published As

Publication number Publication date
CN101970679A (zh) 2011-02-09
EP2225390A1 (en) 2010-09-08
JP2011508602A (ja) 2011-03-17
JP2015091231A (ja) 2015-05-14
US8785162B2 (en) 2014-07-22
WO2009088482A1 (en) 2009-07-16
US20110020882A1 (en) 2011-01-27
AU2008347048B2 (en) 2014-06-05
BRPI0822219A2 (pt) 2014-11-04
EP2225390A4 (en) 2012-05-09
CA2726928A1 (en) 2009-07-16
AU2008347048A1 (en) 2009-07-16
JP5683962B2 (ja) 2015-03-11

Similar Documents

Publication Publication Date Title
CN101970679B (zh) 氨基转移酶和氧化还原酶核酸和多肽和使用方法
EP2089529B1 (en) Production of stereoisomers of monatin via d-tryptophan
US7582455B2 (en) Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
CN112105734A (zh) 生产色胺的方法
US20110045547A1 (en) Isomerases and epimerases and methods of using
JP2005525100A (ja) アラニン２，３−アミノムターゼ
CN101365787B (zh) 用于生产莫纳甜的立体异构体和其前体的多肽和生物合成途径
CN108463555A (zh) 生产苯甲醛的方法
US20250304926A1 (en) Engineered cells for production of indole-derivatives
KR20120068872A (ko) 모나틴의 제조 방법
CN114555779A (zh) 基因重组微生物和二胺化合物的制造方法
Liu et al. The 138th residue of acetohydroxyacid synthase in Corynebacterium glutamicum is important for the substrate binding specificity
US10202627B2 (en) Method for producing trehangelin
CN101052707B (zh) 生产l-氨基酸的方法
Ferrer et al. L-serine biosensor-controlled fermentative production of l-tryptophan derivatives by Corynebacterium glutamicum. Biology. 2022; 11: 744
US20100047861A1 (en) Process for producing useful substance
WO2009088442A2 (en) Isomerases and epimerases and methods of using
JPWO2008126785A1 (ja) 有用物質の製造法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150422

Termination date: 20191231

CF01 Termination of patent right due to non-payment of annual fee