CN101970679B - 氨基转移酶和氧化还原酶核酸和多肽和使用方法 - Google Patents

氨基转移酶和氧化还原酶核酸和多肽和使用方法 Download PDF

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Publication number
CN101970679B
CN101970679B CN200880127576.7A CN200880127576A CN101970679B CN 101970679 B CN101970679 B CN 101970679B CN 200880127576 A CN200880127576 A CN 200880127576A CN 101970679 B CN101970679 B CN 101970679B
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seq
dat
monatin
polypeptide
sequence
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Expired - Fee Related
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CN200880127576.7A
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English (en)
Chinese (zh)
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CN101970679A (zh
Inventor
M·L.·德苏扎
P·M.·希克斯
S·R.·科尔曼
J·M.·拉普拉萨
J·M.·伦多尔夫
S·C.·麦克法伦
E·马拉斯科
牛伟
F·A.·桑切斯-列拉
C·索尔海德
D·P.·魏纳
P·卢京比尔
A·布埃诺
J·昆卡
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Cargill Inc
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Cargill Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN200880127576.7A 2008-01-03 2008-12-31 氨基转移酶和氧化还原酶核酸和多肽和使用方法 Expired - Fee Related CN101970679B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1881408P 2008-01-03 2008-01-03
US61/018,814 2008-01-03
PCT/US2008/014137 WO2009088482A1 (en) 2008-01-03 2008-12-31 Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using

Publications (2)

Publication Number Publication Date
CN101970679A CN101970679A (zh) 2011-02-09
CN101970679B true CN101970679B (zh) 2015-04-22

Family

ID=40853332

Family Applications (1)

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CN200880127576.7A Expired - Fee Related CN101970679B (zh) 2008-01-03 2008-12-31 氨基转移酶和氧化还原酶核酸和多肽和使用方法

Country Status (8)

Country Link
US (1) US8785162B2 (https=)
EP (1) EP2225390A4 (https=)
JP (2) JP5683962B2 (https=)
CN (1) CN101970679B (https=)
AU (1) AU2008347048B2 (https=)
BR (1) BRPI0822219A2 (https=)
CA (1) CA2726928A1 (https=)
WO (1) WO2009088482A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US7572607B2 (en) * 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
EP2090173A1 (en) * 2003-08-01 2009-08-19 Cargill, Incorporated Monatin tabletop sweetener compositions and methods of making same
ES2285521T3 (es) * 2003-08-14 2007-11-16 Cargill, Incorporated Composiciones de goma de mascar que comprenden monatina y procedimientos para la preparacion de las mismas.
AU2004268594A1 (en) * 2003-08-25 2005-03-10 Cargill, Incorporated Beverage compositions comprising monatin and methods of making same
US8206955B2 (en) * 2003-10-21 2012-06-26 Cargill, Incorporated Production of monatin and monatin precursors
US8158389B2 (en) * 2005-04-20 2012-04-17 Cargill, Incorporated Products and methods for in vivo secretion of monatin
RU2007142666A (ru) * 2005-04-20 2009-05-27 Карджилл, Инкорпорейтед (Us) Продукты и способы для секреции монатина in vivo
US8076108B2 (en) * 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
MX2008011477A (es) 2006-03-07 2008-09-23 Cargill Inc Aldolasas, acidos nucleicos que las codifican y metodos para hacerlas y usarlas.
US20090198072A1 (en) * 2006-05-24 2009-08-06 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions
US10332562B2 (en) * 2007-04-17 2019-06-25 Sirius-Beta Corporation System and method for space-time annotation-capable media scrubbing
US8003361B2 (en) * 2007-10-01 2011-08-23 Cargill Incorporated Production of monatin enantiomers
US8076107B2 (en) * 2007-10-01 2011-12-13 Cargill, Incorporated Production of monatin stereoisomers
US8367847B2 (en) * 2007-10-01 2013-02-05 Cargill, Incorporated Production of monatin enantiomers
CA2710683A1 (en) 2008-01-03 2009-07-16 Verenium Corporation Transferases and oxidoreductases, nucleic acids encoding them and methods for making and using them
EP2684953B1 (en) * 2011-03-11 2017-06-28 Kaneka Corporation Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same
MX2013011294A (es) 2011-03-30 2014-10-06 Univ Texas Metodos y composiciones para dirigir celulas adiposas en mamiferos.
DK2961844T3 (da) * 2013-02-28 2019-01-02 Codexis Inc Modificerede transaminasepolypeptider til industriel biokatalyse
US11191555B2 (en) 2017-05-12 2021-12-07 Covidien Lp Retrieval of material from vessel lumens
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
WO2020185971A1 (en) 2019-03-11 2020-09-17 Aldevron, Llc Growing bacterial host cells in gas-permeable low-density polyethylene bags to produce plasmid dna or recombinant molecules
WO2023056388A1 (en) * 2021-09-29 2023-04-06 Ionis Pharmaceuticals, Inc. Conjugated oligonucleotides and uses thereof
CN114317629B (zh) * 2021-12-31 2024-08-27 山西大学 一种转氨酶连续化反应制备手性胺的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007133183A2 (en) * 2006-04-26 2007-11-22 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099848A (en) * 1997-11-18 2000-08-08 The Trustees Of The University Of Pennsylvania Immunogenic compositions comprising DAL/DAT double-mutant, auxotrophic, attenuated strains of Listeria and their methods of use
US7572607B2 (en) * 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
WO2003091396A2 (en) * 2002-04-23 2003-11-06 Cargill, Incorporated Polypeptides and biosynthetic pathways
WO2004085624A2 (en) * 2003-03-24 2004-10-07 Diversa Corporation Transaminases, deaminases and aminomutases and compositions and methods for enzymatic detoxification
AU2004268594A1 (en) * 2003-08-25 2005-03-10 Cargill, Incorporated Beverage compositions comprising monatin and methods of making same
US8076108B2 (en) 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US7888081B2 (en) 2006-05-24 2011-02-15 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007133183A2 (en) * 2006-04-26 2007-11-22 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Also Published As

Publication number Publication date
EP2225390A1 (en) 2010-09-08
EP2225390A4 (en) 2012-05-09
WO2009088482A1 (en) 2009-07-16
AU2008347048A1 (en) 2009-07-16
AU2008347048B2 (en) 2014-06-05
CN101970679A (zh) 2011-02-09
JP5683962B2 (ja) 2015-03-11
JP2015091231A (ja) 2015-05-14
BRPI0822219A2 (pt) 2014-11-04
US8785162B2 (en) 2014-07-22
JP2011508602A (ja) 2011-03-17
US20110020882A1 (en) 2011-01-27
CA2726928A1 (en) 2009-07-16

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